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| 1 | SHRIMP U-Pb zircon dating for lamprophyre from Liaodong Peninsula: Constraints on the initial time of Mesozoic lithosphere thinning beneath eastern China显示文摘It is undebated fact that the lithospheric mantle beneath eastern China was considerably thinned during the Mesozoic time. However, it has no adequate evidence for the exact timing when the lithosphere thinning started. The Liaodong Peninsula is located in the eastern segment of the North China Craton and is one of the important domains to explore the event of lithosphere thinning. SHRIMP U-Pb zircon dating and geochemical study were carried out for the lamprophyre dike swarm that intruded into the magnesite ore-beds in the Dashiqiao Formation of Paleoproterozoic Liaohe Group at the Huaziyu magnesite ore district, Liaodong Peninsula. The results indicate that these lampro- phyre dikes were intruded in late Jurassic (155±4 Ma) and show some geochemical characteristics of potassic magmas. It is now accepted that the lithosphere thinning took place in the late Mesozoic, and the peak thinning stage occurred in early Cretaceous (130―120 Ma). Considering the potassic mafic magmatism marking the onset of the lithospheric thin- ning, we therefore suggest that the studied late Jurassic potassic lamprophyre dike swarm could imply that the late Jurassic is the time that lithosphere thinning started. | JIANG Yaohui JIANG Shaoyong ZHAO Kuidong NI Pei LING Hongfei LIU Dunyi | 2005 | Chinese Science Bulletin2005，50，22： | 22 |
| 2 | Numerical Prediction and Performance Experiment in a Deep-well Centrifugal Pump with Different Impeller Outlet Width显示文摘The existing research of the deep-well centrifugal pump mainly focuses on reduce the manufacturing cost and improve the pump performance,and how to combine above two aspects together is the most difficult and important topic.In this study,the performances of the deep-well centrifugal pump with four different impeller outlet widths are studied by the numerical,theoretical and experimental methods in this paper.Two stages deep-well centrifugal pump equipped with different impellers are simulated employing the commercial CFD software to solve the Navier-Stokes equations for three-dimensional incompressible steady flow.The sensitivity analyses of the grid size and turbulence model have been performed to improve numerical accuracy.The flow field distributions are acquired and compared under the design operating conditions,including the static pressure,turbulence kinetic energy and velocity.The prototype is manufactured and tested to certify the numerical predicted performance.The numerical results of pump performance are higher than the test results,but their change trends have an acceptable agreement with each other.The performance results indicted that the oversize impeller outlet width leads to poor pump performances and increasing shaft power.Changing the performance of deep-well centrifugal pump by alter impeller outlet width is practicable and convenient,which is worth popularizing in the engineering application.The proposed research enhances the theoretical basis of pump design to improve the performance and reduce the manufacturing cost of deep-well centrifugal pump. | SHI Weidong ZHOU Ling LU Weigang PEI Bing LANG Tao | 2013 | Chinese Journal of Mechanical Engineering2013，26，1： | 20 |
| 3 | Multimorbidity patterns and association with mortality in 0.5 million Chinese adults显示文摘Background:Few studies have assessed the relationship between multimorbidity patterns and mortality risk in the Chinese population.We aimed to identify multimorbidity patterns and examined the associations of multimorbidity patterns and the number of chronic diseases with the risk of mortality among Chinese middle-aged and older adults.Methods:We used data from the China Kadoorie Biobank and included 512,723 participants aged 30 to 79 years.Multimorbidity was defined as the presence of two or more of the 15 chronic diseases collected by self-report or physical examination at baseline.Multimorbidity patterns were identified using hierarchical cluster analysis.Cox regression was used to estimate the associations of multimorbidity patterns and the number of chronic diseases with all-cause and cause-specific mortality.Results:Overall,15.8%of participants had multimorbidity.The prevalence of multimorbidity increased with age and was higher in urban than rural participants.Four multimorbidity patterns were identified,including cardiometabolic multimorbidity(diabetes,coronary heart disease,stroke,and hypertension),respiratory multimorbidity(tuberculosis,asthma,and chronic obstructive pulmonary disease),gastrointestinal and hepatorenal multimorbidity(gallstone disease,chronic kidney disease,cirrhosis,peptic ulcer,and cancer),and mental and arthritis multimorbidity(neurasthenia,psychiatric disorder,and rheumatoid arthritis).During a median of 10.8 years of follow-up,49,371 deaths occurred.Compared with participants without multimorbidity,cardiometabolic multimorbidity(hazard ratios[HR]=2.20,95%confidence intervals[CI]:2.14-2.26)and respiratory multimorbidity(HR=2.13,95%CI:1.97-2.31)demonstrated relatively higher risks of mortality,followed by gastrointestinal and hepatorenal multimorbidity(HR=1.33,95%CI:1.22-1.46).The mortality risk increased by 36%(HR=1.36,95%CI:1.35-1.37)with every additional disease.Conclusion:Cardiometabolic multimorbidity and respiratory multimorbidity posed the highest threat on mortality risk and deserved particular attention in Chinese adults. | Junning Fan Zhijia Sun Canqing Yu Yu Guo Pei Pei Ling Yang Yiping Chen Huaidong Du Dianjianyi Sun Yuanjie Pang Jun Zhang Simon Gilbert Daniel Avery Junshi Chen Zhengming Chen Jun Lyu Liming Li On Behalf of the China Kadoorie Biobank Collaborative Group | 2022 | Chinese Medical Journal2022，，6： | 17 |
| 4 | X-ray image characteristics and related measurements in the ankles of 118 adult patients with Kashin-Beck disease显示文摘 | Zeng Yi Zhou Zongke Shen Bin Yang Jing Kang Pengde Zhou Xuan Zou Ling Pei Fuxing | 2014 | Chinese Medical Journal2014，，13： | 13 |
| 5 | Long-term Efficacy of Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease: A 5-year Follow-up Study in China显示文摘 | Lu-Lu Jiang Jin-Long Liu Xiao-Li Fu Wen-Biao Xian Jing Gu Yan-Mei Liu Jing Ye Jie Chen Hao Qian Shao-Hua Xu Zhong Pei Ling Chen | 2015 | Chinese Medical Journal2015，，18： | 13 |
| 6 | Effects of acupuncturing Tsusanli (S_T36) on expression of nitric oxide synthase in hypothalamus and adrenal gland in rats with cold stress ulcer显示文摘AIM: To study the protective effect of acupuncturing Tsusanli (ST36) on cold stress ulcer, and the expression of nitric oxide synthase (NOS) in hypothalamus and adrenal gland.METHODS: Ulcer index in rats and RT-PCR were used to study the protective effect of acupuncture on cold stress ulcer, and the expression of NOS in hypothalamus and adrenal gland. Images were analyzed with semi-quantitative method.RESULTS: The ulcer index significantly decreased in rats with stress ulcer. Plasma cortisol concentration was up regulated during cold stress, which could be depressed by pre-acupuncture. The expression of NOS1 in hypothalamus increased after acupuncture. The increased expression of NO$2 was related with stress ulcer, which could be decreased by acupuncture. The expression of NOS3 in hypothalamus was similar to NOS2, but the effect of acupuncture was limited. The expression of NOS2 and NOS3 in adrenal gland increased after cold stress, only the expression of NOS1 could be repressed with acupuncture. There was no NOS2 expression in adrenal gland in rats with stress ulcer.CONCLUSION: The protective effect of acupuncturing Tsusanli (Sr36) on the expression of NOS in hypothalamus and adrenal gland can be achieved. | Jin-Ping Sun Hai-Tao Pei Xiang-Lan Jin Ling Yin Qing-Hua Tian Shu-Jun Tian | 2005 | World Journal of Gastroenterology2005，11，32： | 10 |
| 7 | Clinical features and long-term prognosis of patients with anomalous origin of the left coronary artery from the pulmonary artery显示文摘从肺的动脉(ALCAPA ) 的左冠的动脉的背景异常起源是一个稀罕的先天的心异例。我们试图与 ALCAPA.Methods 说明临床的特征和病人的长期的预后 23 个病人( 13 男性和 10 女性,年龄从 2.5 个月 到 65 年)在北京 Anzhen 作为 ALCAPA 鉴别到2009年6月的从1984年4月的医院被划分成二个组,基于发作的年龄:组 1 (12 个月, n=16 ) 并且组 2 (12 个月, n=7 ) 56 削尖的 .Results 在组 1 的百分之三个病人作为 endocardial fibroelastosis (9/16 ) 被误诊, 18.8% 是扩大了心肌症(3/16 ) 和 6.3% 同样心肌的梗塞(1/16 ) 。在组 2 的病人通常作为冠的心疾病,心肌炎,或专利 ductus arteriosus 被诊断。在组 1 揭示反常 Q 的 Electrocardiography 处于领先与 T 波浪倒置飘动我, avL, V4-V6,特别在铅 avL (深、宽的 Q 波浪) ;但是在组 2 的没有特定的表明。在组 1 的病人的一个更高的百分比在胸拍上有心脏扩大症(86.7% 对 33.3% , P=0.031 ) 当肺的动脉伸出在组 2 是更普通的时(26.7% 对 83.3% , P=0.046 ) 。更低的左室的喷射部分(LVEF ) 在比在组 2 的组 1 是在场的((48.5 ? 桴 ? 慢吗? | ZHENG Jian-yong HAN Ling DING Wen-hong JIN Mei ZHANG Gui-zhen XIAO Yan-yan LUO Yi CHENG Pei MENG Xu ZHAO Qu-ming | 2010 | Chinese Medical Journal2010，，20： | 10 |
| 8 | A novel anticancer property of Lycium barbarum polysaccharide in triggering ferroptosis of breast cancer cells显示文摘Breast cancer is one of the most malignant tumors and is associated with high mortality rates among women.Lycium barbarum polysaccharide(LBP)is an extract from the fruits of the traditional Chinese herb,L.barbarum.LBP is a promising anticancer drug,due to its high activity and low toxicity.Although it has anticancer properties,its mechanisms of action have not been fully established.Ferroptosis,which is a novel anticancer strategy,is a cell death mechanism that relies on iron-dependent lipid reactive oxygen species(ROS)accumulation.In this study,human breast cancer cells(Michigan Cancer Foundation-7(MCF-7)and MD Anderson-Metastatic Breast-231(MDA-MB-231))were treated with LBP.LBP inhibited their viability and proliferation in association with high levels of ferroptosis.Therefore,we aimed to ascertain whether LBP reduced cell viability through ferroptosis.We found that the structure and function of mitochondria,lipid peroxidation,and expression of solute carrier family 7 member 11(SLC7 A11,also known as x CT,the light-chain subunit of cystine/glutamate antiporter system X_(c)^(-))and glutathione peroxidase 4(GPX4)were altered by LBP.Moreover,the ferroptosis inhibitor,Ferrostatin-1(Fer-1),rescued LBP-induced ferroptosis-associated events including reduced cell viability and glutathione(GSH)production,accumulation of intracellular free divalent iron ions and malondialdehyde(MDA),and down-regulation of the expression of x CT and GPX4.Erastin(x CT inhibitor)and RSL3(GPX4 inhibitor)inhibited the expression of x CT and GPX4,respectively,which was lower after the co-treatment of LBP with Erastin and RSL3.These results suggest that LBP effectively prevents breast cancer cell proliferation and promotes ferroptosis via the x CT/GPX4 pathway.Therefore,LBP exhibits novel anticancer properties by triggering ferroptosis,and may be a potential therapeutic option for breast cancer. | Xing DU Jingjing ZHANG Ling LIU Bo XU Hang HAN Wenjie DAI Xiuying PEI Xufeng FU Shaozhang HOU | 2022 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2022，23，4： | 10 |
| 9 | Hypoxia increases adipogenesis and affects adipocytokine production in orbital fibroblasts-a possible explanation of the link between smoking and Graves' ophthalmopathy显示文摘AIM:To assess the effects of hypoxia on human orbital fibroblasts(OF)on adipogenesis and adipocytokine production.METHODS:Human OF were derived from tissues obtained from patients with Graves'ophthalmopathy(GO)and from patients without known thyroid diseases undergoing blepharoplasty.The OF were cultured separately under normoxic and hypoxic conditions.Comparisons of adipocytokine concentrations using multiplex ELISA and lipid accumulation in the cells using Oil Red O staining were subsequently performed.RESULTS:There was increased adipogenesis in OF from GO subject when exposed to hypoxic culture conditions.This was not observed in OF from normal controls.Hypoxia led to an increase in leptin and a decrease in MCP-1 secretion in OF cultures.CONCLUSION:Hypoxia induces adipogenesis in OF and may represent a mechanism by which smoking contributes to deterioration of GO.We also found novel changes to leptin and MCP-1 production in OF cultures exposed to hypoxia suggesting important roles of these cytokines in the disease process. | Chiaw Ling Chng Oi Fah Lai Charmaine Sze-Min Chew Yu Pei Peh Stephanie Man-Chung Fook-Chong Lay Leng Seah Daphne Hsu-Chin Khoo | 2014 | International Journal of Ophthalmology(English edition)2014，7，3： | 10 |
| 10 | Allele-aware chromosome-level genome assembly of Artemisia annua reveals the correlation between ADS expansion and artemisinin yield显示文摘Artemisia annua is the major natural source of artemisinin,an anti-malarial medicine commonly used worldwide.Here,we present chromosome-level haploid maps for two A.annua strains with different artemisinin contents to explore the relationships between genomic organization and artemisinin production.High-fidelity sequencing,optical mapping,and chromatin conformation capture sequencing were used to assemble the heterogeneous and repetitive genome and resolve the haplotypes of A.annua.Approximately 5o,ooo genes were annotated for each haplotype genome,and a triplication event that occurred approximately 58.12million years ago was examined for the first time in this species.A total of 3,903,467-5,193,414 variants(SNPs,indels,and structural variants)were identified in the 1.5-Gb genome during pairwise comparison between haplotypes,consistent with the high heterozygosity of this species.Genomic analyses revealed a correlation between artemisinin concents and the copy number of amorpha-4,11-dienes ynthasegenes.This correlation was further confirmed by resequencing of 36A.annua samples with varied artemisinin contents.Circular consensus sequencing of transcripts facilitated the detection of paralog expression.Collectively,our study provides chromosome-level allele-aware genome assemblies for two A.annua strains and new insights into the biosynthesis of artemisinin and its regulation,which will contribute to conquering malaria worldwide. | Baosheng Liao Xiaofeng Shen Li Xiang Shuai Guo Shiyu Chen Ying Meng Yu Liang Dandan Ding Junqi Bai Dong Zhang Tomasz Czechowski Yi Li Hui Yao Tingyu Mai Caroline Howard Chao Sun Haitao Liu Jiushi Liu Jin Pei Jihai Gao Jigang Wang Xiaohui Qiu Zhihai Huang Hongyi Li Ling Yuan Jianhe Wei lan Graham Jiang Xu Boli Zhang Shilin Chen | 2022 | Molecular Plant2022，15，8： | 9 |
| 11 | Analysis of Health Service Utilization and its Influencing Factors among Patients with Pneumoconiosis in China显示文摘Pneumoconiosis,an interstitial lung disease that occurs from breathing in certain kinds of damaging dust particles,is a major occupational disease in China.Patients diagnosed with occupational pneumoconiosis can avail of free medical treatment,whereas patients without a diagnosis of occupational diseases cannot not claim free medical treatment in most provinces from the government before 2019.This study aimed to analyze the priority of medical facility selection and its influencing factors among patients with pneumoconiosis. | WANG Huan Qiang JIA Jun Lin JIANG Zhao Qiang JIN Qi LI Dong Xia LING Rui Jie LI Ying CUI Ping CHEN Gang ZHAO Hong Yu LI Yan WEN Ke LYU Xiang Pei LOU Jian Lin LI Tao | 2021 | Biomedical and Environmental Sciences2021，34，1： | 9 |
| 12 | Efficacy and safety of Xinglouchengqi decoction for acute ischemic stroke with constipation:study protocol for a randomized con-trolled trial显示文摘OBJECTIVE: To investigate the efficacy and safety of Xinglouchengqi(XLCQ) decoction in treatment of acute ischemic stroke with constipation.METHODS: In this prospective, multicenter, assessor-blinded, randomized controlled trial, 360 eligible participants will be randomized to the XLCQ group or the control group. Participants in the XLCQ group will receive XLCQ decoction, while those in the control group will undergo clysis therapy using glycerin enemas or oral administration of lactulose solution. Both groups will undergo a treatment period of(5 ± 2) d and a 1-month follow-up.The primary outcome measure will be the Constipation Scale score. The secondary outcome measures will include scores on the National Institutes of Health Stroke Scale, the Traditional Chinese Medicine(TCM) Stroke Scale, the Diagnostic Scale for TCM Syndromes of Ischemic Stroke and TCM Scale for Syndrome of Phlegm-heat and Fu-organ Excess.Therapeutic mechanism outcomes and safety outcomes will also be assessed. Assessments will be conducted at baseline, at the end of the treatment period, and at the follow-up. Moreover, daily visits will be scheduled to grade the status of constipation during the treatment period.DISCUSSION: The results of this study will provide scientific and objective data with which to assess the efficacy and safety of XLCQ decoction for patients with acute ischemic stroke and constipation. | Chen Pei Zhang Yong Ling Lili Chen Xing Ren Yi Jiang Lan Wu Shuang Wang Wenting Wang Yuguang Zou Yihuai | 2017 | Journal of Traditional Chinese Medicine2017，37，6： | 7 |
| 13 | Evaluation of entropy for monitoring the depth of anesthesia :ompared with bispectral index: a multicenter clinical trial显示文摘 | GAO Jian-dong ZHAO Yu-jie XU Chen-shi ZHAO Jing HUANG Yu-guang WANG Tian-long PEI Ling WANG Jian YAO Li-nong DING Qian TAN Zhi-ming ZHU Zhi-rong YUE Yun | 2012 | Chinese Medical Journal2012，，8： | 7 |
| 14 | Mobile Web Augmented Reality in 5G and Beyond:Challenges, Opportunities, and Future Directions显示文摘The popularity of wearable devices and smartphones has fueled the development of Mobile Augmented Reality(MAR),which provides immersive experiences over the real world using techniques,such as computer vision and deep learning.However,the hardware-specific MAR is costly and heavy,and the App-based MAR requires an additional download and installation and it also lacks cross-platform ability.These limitations hamper the pervasive promotion of MAR.This paper argues that mobile Web AR(MWAR)holds the potential to become a practical and pervasive solution that can effectively scale to millions of end-users because MWAR can be developed as a lightweight,cross-platform,and low-cost solution for end-to-end delivery of MAR.The main challenges for making MWAR a reality lie in the low efficiency for dense computing in Web browsers,a large delay for real-time interactions over mobile networks,and the lack of standardization.The good news is that the newly emerging 5G and Beyond 5G(B5G)cellular networks can mitigate these issues to some extent via techniques such as network slicing,device-to-device communication,and mobile edge computing.In this paper,we first give an overview of the challenges and opportunities of MWAR in the 5G era.Then we describe our design and development of a generic service-oriented framework(called MWAR5)to provide a scalable,flexible,and easy to deploy MWAR solution.We evaluate the performance of our MWAR5 system in an actually deployed 5G trial network under the collaborative configurations,which shows encouraging results.Moreover,we also share the experiences and insights from our development and deployment,including some exciting future directions of MWAR over 5G and B5G networks. | Xiuquan Qiao Pei Ren Guoshun Nan Ling Liu Schahram Dustdar Junliang Chen | 2019 | China Communications2019，16，9： | 7 |
| 15 | High Levels of Hepatitis B Surface Antigen Increase Risk of Hepatocellular Carcinoma in Patients With Low HBV Load显示文摘 | Tai–Chung Tseng Chun–Jen Liu Hung–Chih Yang Tung–Hung Su Chia–Chi Wang Chi–Ling Chen Stephanie Fang–Tzu Kuo Chen–Hua Liu Pei–Jer Chen Ding–Shinn Chen Jia–Horng Kao | 2012 | Gastroenterology2012，，5： | 6 |
| 16 | Hypoxia inducible factor-1alpha mediates protection of DL-3-n-butylphthalide in brain microvascular endothelial cells against oxygen glucose deprivation-induced injury显示文摘Studies have demonstrated that DL-3-n-butylphthalide can significantly alleviate oxygen glucose deprivation-induced injury of human umbilical vein endothelial cells at least partly associated with its enhancement on oxygen glucose deprivation-induced hypoxia inducible factor-1α expression.In this study,we hypothesized that DL-3-n-butylphthalide can protect against oxygen glucose deprivation-induced injury of newborn rat brain microvascular endothelial cells by means of upregulating hypoxia inducible factor-1α expression.MTT assay and Hoechst staining results showed that DL-3-n-butylphthalide protected brain microvascular endothelial cells against oxygen glucose deprivation-induced injury in a dose-dependent manner.Western blot and immunofluorescent staining results further confirmed that the protective effect was related to upregulation of hypoxia inducible factor-1α.Real-time RT-PCR reaction results showed that DL-3-n-butylphthalide reduced apoptosis by inhibiting downregulation of pro-apoptotic gene caspase-3 mRNA expression and upregulation of apoptosis-executive protease bcl-2 mRNA expression;however,DL-3-n-butylphthalide had no protective effects on brain microvascular endothelial cells after knockdown of hypoxia inducible factor-1α by small interfering RNA.These findings suggest that DL-3-n-butylphthalide can protect brain microvascular endothelial cells against oxygen glucose deprivation-induced injury by upregulating bcl-2 expression and downregulating caspase-3 expression though hypoxia inducible factor-1α pathway. | Weihong Yang Ling Li Ruxun Huang Zhong Pei Songjie Liao Jinsheng Zeng | 2012 | Neural Regeneration Research2012，7，12： | 6 |
| 17 | CD147 antibody specifically and effectively inhibits infection and cytokine storm of SARS-CoV-2 and its variants delta,alpha,beta,and gamma显示文摘SARS-CoV-2 mutations contribute to increased viral transmissibility and immune escape,compromising the effectiveness of existing vaccines and neutralizing antibodies.An in-depth investigation on COVID-19 pathogenesis is urgently needed to develop a strategy against SARS-CoV-2 variants.Here,we identified CD147 as a universal receptor for SARS-CoV-2 and its variants.Meanwhile,Meplazeumab,a humanized anti-CD147 antibody,could block cellular entry of SARS-CoV-2 and its variants-alpha,beta,gamma,and delta,with inhibition rates of 68.7,75.7,52.1,52.1,and 62.3%at 60μg/ml,respectively.Furthermore,humanized CD147 transgenic mice were susceptible to SARS-CoV-2 and its two variants,alpha and beta.When infected,these mice developed exudative alveolar pneumonia,featured by immune responses involving alveoli-infiltrated macrophages,neutrophils,and lymphocytes and activation of IL-17 signaling pathway.Mechanistically,we proposed that severe COVID-19-related cytokine storm is induced by a'spike protein-CD147-CyPA signaling axis':Infection of SARS-CoV-2 through CD147 initiated the JAK-STAT pathway,which further induced expression of cyclophilin A(CyPA);CyPA reciprocally bound to CD147 and triggered MAPK pathway.Consequently,the MAPK pathway regulated the expression of cytokines and chemokines,which promoted the development of cytokine storm.Importantly,Meplazumab could effectively inhibit viral entry and inflammation caused by SARS-CoV-2 and its variants.Therefore,our findings provided a new perspective for severe COVID-19-related pathogenesis.Furthermore,the validated universal receptor for SARS-CoV-2 and its variants can be targeted for COVID-19 treatment. | Jiejie Geng Liang Chen Yufeng Yuan Ke Wang Youchun Wang Chuan Qin Guizhen Wu Ruo Chen Zheng Zhang Ding Wei Peng Du Jun Zhang Peng Lin Kui Zhang Yongqiang Deng Ke Xu Jiangning Liu Xiuxuan Sun Ting Guo Xu Yang Jiao Wu Jianli Jiang Ling Li Kun Zhang Zhe Wang Jing Zhang Qingguo Yan Hua Zhu Zhaohui Zheng Jinlin Miao Xianghui Fu Fengfan Yang Xiaochun Chen Hao Tang Yang Zhang Ying Shi Yumeng Zhu Zhuo Pei Fei Huo Xue Liang Yatao Wang Qingyi Wang Wen Xie Yirong Li Mingyan Shi Huijie Bian Ping Zhu Zhi-Nan Chen | 2021 | Signal Transduction and Targeted Therapy2021，6，10： | 6 |
| 18 | A study on the pathogen species and physiological races of tomato Fusarium wilt in Shanxi,China显示文摘In order to clarify the main pathogens of tomato Fusarium wilt in Shanxi Province, China, morphological identification, elongation factor 1 alpha(EF-1α) sequence analysis, specific primer amplification and pathogenicity tests were applied to study the isolates which were recovered from diseased plants collected from 17 different districts of Shanxi Province. The results were as follows: 1) Through morphological and molecular identification, the following 7 species of Fusarium were identified: F. oxysporum, F. solani, F. verticillioides, F. subglutinans, F. chlamydosporum, F. sporotrichioides, and F. semitectum; 2) 56 isolates of F. oxysporum were identified using specific primer amplification, among which, 29, 5 and 6 isolates were respectively identified as F. oxysporum f. sp. lycopersici physiological race 1, race 2, and race 3; 3) pathogenicity test indicated the significant pathogenicity of F. oxysporum, F. solani, F. verticillioides, and F. subglutinans to tomato plant. Therefore, among these 4 species confirmed as pathogenic to tomato in Shanxi, the highest isolation rate(53.3%) corresponded to F. oxysporum. Three physiological species, race 1, race 2, and race 3 of F. oxysporum f. sp. lycopersici are detected in Shanxi, among which race 1 is the most widespread pathogen and is also considered as the predominant race. | CHANG Yin-dong DU Bin WANG Ling JI Pei XIE Yu-jie LI Xin-feng LI Zhi-gang WANG Jian-ming | 2018 | Journal of Integrative Agriculture2018，17，6： | 6 |
| 19 | Transporter-Mediated Nuclear Entry of Jasmonoyl-lsoleucine Is Essential for Jasmonate Signaling显示文摘到由直接对荷尔蒙集中作出回应的控制基因表示,动物和植物房间利用了可比较的机制在原子核察觉到小分子的荷尔蒙。这些荷尔蒙的原子入口是否活跃地通常被搬运或消极地扩散了,,,要求了,通过原子毛孔建筑群,仍然保持神秘。这里,我们在 Arabidopsis thaliana 识别了并且描绘 jasmonate transporter, AtJAT1/AtABCG16,哪个展览在原子信封和血浆的意外双本地化膜。我们证明 AtJAT1/AtABCG16 由两个都调停控制 jasmonate 植物激素的细胞质、原子的分区 jasmonic 酸(JA ) 和 jasmonoyl 异白氨酸(JA-Ile ) 的原子流入的细胞的流出,并且为维持批评原子 JA-Ile 集中激活 JA 发信号是必要的。这些结果说明小荷尔蒙分子的那个调停运输的原子条目调整原子荷尔蒙的新机制正在发信号。我们的调查结果提供一条大街开发指向小分子的原子入口的药品的代理人。 | Qingqing Li Jian Zheng Shuaizhang Li Guanrong Huang Stephen J. Skilling Lijian Wang Ling Li Mengya Li Lixing Yuan Pei Liu | 2017 | Molecular Plant2017，10，5： | 6 |
| 20 | Wearable CNT/Ti_(3)C_(2)T_(x)MXene/PDMS composite strain sensor with enhanced stability for real-time human healthcare monitoring显示文摘Strain sensors with good stability are vital to the development of wearable healthcare monitoring systems.However,the design of strain sensor with both duration stability and environmental stability is still a challenge.In this work,we propose an ultra-stable and washable strain sensor by embedding a coupled composite film of carbon nanotube(CNT)and Ti_(3)C_(2)T_(x) MXene into polydimethylsiloxane(PDMS)matrix.The composite strain sensor with embedded microstructure and uneven surface makes it conformal to skin,while the CNT/MXene sensing layer exhibits a resistance sensitive to strain.This sensor shows reliable responses at different frequencies and with long-term cycling durability(over 1,000 cycles).Meanwhile,the CNT/MXene/PDMS composite strain sensor provides the advantages of superior anti-interference to temperature change and water washing.The results demonstrate less than 10%resistance changes as the temperature rises from-20 to 80℃or after sonication in water for 120 min,respectively.The composite sensor is applied to monitor human joint motions,such as bending of finger,wrist and elbow.Moreover,the simultaneous monitoring of the electrocardiogram(ECG)signal and joint movement while riding a sports bicycle is demonstrated,enabling the great potential of the as-fabricated sensor in real-time human healthcare monitoring. | Xiaowen Xu Yucheng Chen Pei He Song Wang Kai Ling Longhui Liu Pengfei Lei Xianjun Huang Hu Zhao Jianyun Cao Junliang Yang | 2021 | Nano Research2021，14，8： | 5 |
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