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| 1 | China Argo project:progress in China Argo ocean observations and data applications显示文摘This paper reviews the current achievements of the China Argo project. It considers aspects of both the construction of the Argo observing array, float technology, and the quality control and sharing of its data. The developments of associated data products and data applications for use in the fields of ocean, atmosphere, and climate research are discussed, particularly those related to tropical cyclones(typhoons), ocean circulation,mesoscale eddies, turbulence, oceanic heat/salt storage and transportation, water masses, and operational oceanic/atmospheric/climatic forecasts and predictions. Finally, the challenges and opportunities involved in the long-term maintenance and sustained development of the China Argo ocean observation network are outlined.Discussion also focuses on the necessity for increasing the number of floats in the Indian Ocean and for expanding the regional Argo observation network in the South China Sea, together with the importance of promoting the use of Argo data by the maritime countries of Southeast Asia and India. | LIU Zenghong WU Xiaofen XU Jianping LI Hong LU Shaolei SUN Chaohui CAO Minjie | 2017 | Acta Oceanologica Sinica2017，36，6： | 10 |
| 2 | Distributed Clustering Algorithm for Energy Efficiency and Load-Balance in Large-Scale Multi-Agent Systems显示文摘在大规模多代理人系统改进精力效率和负担平衡,一个大规模分布式的簇算法被建议。起初,描述代理人的空间分发的一个参数被设计估计散布一个代理人的能力的信息。而且,比赛决定机制被建议在大规模 multiagent 系统处理比赛问题。因此,建议算法能平衡负担,局部地调整系统网络并且动态地,减少系统精力消费。最后,模拟被介绍表明建议算法的优势。 | LU Shaolei FANG Hao WEI Yue | 2018 | Journal of Systems Science & Complexity2018，31，1： | 3 |
| 3 | Influence of ENSO Events on Tropical Cyclone Activity over the Western North Pacific显示文摘Based on an analysis of 51-year (1965 2015) data, the influence of El Ni o Southern Oscillation (ENSO) events on tropical cyclone (TC) activity is examined over the western North Pacific (WNP). The total number of TCs formed in the entire WNP reduces by about 3.4 TCs per year in La Ni a years, whereas TCs have an equivalent genesis number between El Ni o years and climatology. During El Ni o years, the frequency of TC formation increases remarkably in the southeast quadrant (140 E 180 , 0 17 N) and decreases in the northwest quadrant (120 140 E, 17 30 N). During La Ni a years, TCs tend to form in the northwest and southwest quadrants (120 140 E, 0 17 N) quadrants. TCs tend to become long-lived in the peak season (from July to Septem- ber) of El Ni o years and during strong El Ni o events. TC genesis shows a southeastward positive shift in terms of lifetime and intensity during El Ni o years, thus more super TCs (winds ≥ 58.64 m s 1) are formed in the southeast quadrant. Further analysis using the genesis potential index (GPI) indicates that the interannual variations in the TC genesis and track are significantly influenced by a combination of large-scale dynamic and thermodynamic conditions. | LIU Zenghong CHEN Xingrong SUN Chaohui CAO Minjie WU Xiaofen LU Shaolei | 2019 | Journal of Ocean University of China2019，18，4： | 1 |
| 4 | Robust hydrogel sensors for unsupervised learning enabled sign-to-verbal translation显示文摘Highly stretchable and robust strain sensors are rapidly emerging as promising candidates for a diverse of wearable electronics.The main challenge for the practical application of wearable electronics is the energy consumption and device aging.Energy consumption mainly depends on the conductivity of the sensor,and it is a key factor in determining device aging.Here,we design a liq-uid metal(LM)-embedded hydrogel as a sensing material to overcome the bar-rier of energy consumption and device aging of wearable electronics.The sensing material simultaneously exhibits high conductivity(up to 22 S m�1),low elastic modulus(23 kPa),and ultrahigh stretchability(1500%)with excel-lent robustness(consistent performance against 12000 mechanical cycling).A motion monitoring system is composed of intrinsically soft LM-embedded hydrogel as sensing material,a microcontroller,signal-processing circuits,Bluetooth transceiver,and self-organizing map developed software for the visu-alization of multi-dimensional data.This system integrating multiple functions including signal conditioning,processing,and wireless transmission achieves monitor hand gesture as well as sign-to-verbal translation.This approach provides an ideal strategy for deaf-mute communicating with normal people and broadens the application of wearable electronics. | Hude Ma Haiyang Qin Xiao Xiao Na Liu Shaolei Wang Junye Li Sophia Shen Shuqi Dai Mengmeng Sun Peiyi Li Xiaofang Pan Mingjun Huang Baoyang Lu Jun Chen Lidong Wu | 2023 | InfoMat2023，5，7： | 1 |
| 5 | Mosaic representations of videosequences based on slice image analysis显示文摘 | FENG SHAOLEI LU HANQING MA SONGDE | 2002 | Pattern Recognition Letters2002，23，： | 1 |
| 6 | Correlation of ALOX15 expression with eosinophilic or reflux esophagitis in a cohort of pediatric patients with esophageal eosinophilia显示文摘 | Andres Matoso Danisha Allen Michael Herzlinger Jason Ferreira Sonja Chen Shaolei Lu Valeria Fabre Renee Monahan Dongfang Yang Lelia Noble Shamlal Mangray Murray B. Resnick | 2014 | Human Pathology2014，，： | 1 |
| 7 | The metabolite, alpha-ketoglutarate inhibits non-alcoholic fatty liver disease progression by targeting lipid metabolism显示文摘Background:Non-alcoholic liver disease is of increased concern and contributing to economic burdens not only in developing countries but in developed countries as well.Identifying the biomarker of early diagnosis and early intervention approaches for non-alcoholic liver disease is unmet and required further investigation.Although the alpha-ketoglutarate(a-KG)is recently proposed to be a potential biomarker in differentiating patients with obesity from those with non-alcoholic liver disease,how a-ketoglutatate is involved in the fatty liver progression is not clear.Methods:A high-fat diet(HFD)feeding animal model,liver functional assays,and molecular approaches were adopted to clarify the impact of a-KG in fatty liver progression.Results:In the current study,it was found that dietary a-KG would inhibit weight gain in male and female mice fed with a normal chew or HFD.HFD feeding caused fatty liver in male mice,but a-KG treatment could substantially inhibit hepatic steatosis progression.Biochemical studies revealed the possible linkage of a-KG protective functions to lipid metabolism.Further analysis identified the important role of peroxisome proliferator-activated receptors in beneficial a-KG-mediated effects on fatty liver progression.Conclusions:The current study demonstrates the therapeutic potential of a-KG and how it may be used,via dietary supplementation,as a preventive intervention for non-alcoholic liver disease in obese patients. | Katsuya Nagaoka Joud Mulla Kevin Cao Zhixiang Cheng Dan Liu William Mueller Amalia Bay Grace Hildebrand Shaolei Lu Chiung-Kuei Huang | 2020 | Liver Research2020，4，2： | 0 |
| 8 | Molecular profiling reveals potential targets in cholangiocarcinoma显示文摘BACKGROUND Cholangiocarcinoma(CCA)is a devastating malignancy and has a very poor prognosis if tumors spread outside the liver.Understanding the molecular mechanisms underlying the CCA progression will likely yield therapeutic approaches toward treating this deadly disease.AIM To determine the molecular pathogenesis in CCA progression.METHODS In silico analysis,in vitro cell culture,CCA transgenic animals,histological,and molecular assays were adopted to determine the molecular pathogenesis.RESULTS The transcriptomic data of human CCA samples were retrieved from The Cancer Genome Atlas(TGCA,CHOL),European Bioinformatics Institute(EBI,GAD-00001001076),and Gene Expression Omnibus(GEO,GSE107943)databases.Using Gene set enrichment analysis,the cell cycle and Notch related pathways were demonstrated to be significantly activated in CCA in TCGA and GEO datasets.We,through differentially expressed genes,found several cell cycle and notch associated genes were significantly up-regulated in cancer tissues when compared with the non-cancerous control samples.The associated genes,via quantitative real-time PCR and western blotting assays,were further examined in normal human cholangiocytes,CCA cell lines,mouse normal bile ducts,and mouse CCA tumors established by specifically depleting P53 and expressing KrasG12D mutation in the liver.Consistently,we validated that the cell cycle and Notch pathways are up-regulated in CCA cell lines and mouse CCA tumors.Interestingly,targeting cell cycle and notch pathways using small molecules also exhibited significant beneficial effects in controlling tumor malignancy.More importantly,we demonstrated that several cell cycle and Notch associated genes are significantly associated with poor overall survival and disease-free survival using the Log-Rank test.CONCLUSION In summary,our study comprehensively analyzed the gene expression pattern of CCA samples using publicly available datasets and identified the cell cycle and Notch pathways are potential therapeutic targets in this deadly disease. | Dan Liu Yang Shi Hongze Chen Muhammad Azhar Nisar Nicholas Jabara Noah Langwinski Sophia Mattson Katsuya Nagaoka Xuewei Bai Shaolei Lu Chiung-Kuei Huang | 2023 | World Journal of Gastroenterology2023，29，25： | 0 |
| 9 | Inhibition mechanism of air nanobubbles on brass corrosion in circulating cooling water systems显示文摘Air nanobubbles(A-NBs)were used to inhibit the brass corrosion in circulating cooling water for the first time in the study.The results of mass loss method and electrochemical method showed that A-NBs had the obvious corrosion inhibition effect.The inhibition rate reached 52%at 35℃.The impedance and surface characterization results of corrosion samples indicated that the corrosion inhibition mechanisms of A-NBs mainly included adsorption of corrosion ions,promoting the formation of the passivation film on metal surface and the formation of the bubble layer and scale film on metal surface.A-NBs are potential excellent corrosion inhibitors. | Yuling Zhang Shaolei Lu Delie Li Haiyang Duan Congwen Duan Jinghong Zhang Songtao Liu | 2023 | Chinese Journal of Chemical Engineering2023，62，10： | 0 |
| 10 | Twenty years of ocean observations with China Argo显示文摘The international Argo program,a global observational array of nearly 4000 autonomous profiling floats initiated in the late 1990s,which measures the water temperature and salinity of the upper 2000 m of the global ocean,has revolutionized oceanography.It has been recognized one of the most successful ocean observation systems in the world.Today,the proposed decade action“OneArgo”for building an integrated global,full-depth,and multidisciplinary ocean observing array for beyond 2020 has been endorsed.In the past two decades since 2002,with more than 500 Argo deployments and 80 operational floats currently,China has become an important partner of the Argo program.Two DACs have been established to process the data reported from all Chinese floats and deliver these data to the GDACs in real time,adhering to the unified quality control procedures proposed by the Argo Data Management Team.Several Argo products have been developed and released,allowing accurate estimations of global ocean warming,sea level change and the hydrological cycle,at interannual to decadal scales.In addition,Deep and BGC-Argo floats have been deployed,and time series observations from these floats have proven to be extremely useful,particularly in the analysis of synoptic-scale to decadal-scale dynamics.The future aim of China Argo is to build and maintain a regional Argo fleet comprising approximately 400 floats in the northwestern Pacific,South China Sea,and Indian Ocean,accounting for 9%of the global fleet,in addition to maintaining 300 Deep Argo floats in the global ocean(25%of the global Deep Argo fleet).A regional BGC-Argo array in the western Pacific also needs to be established and maintained. | Zenghong Liu Xiaogang Xing Zhaohui Chen Shaolei Lu Xiaofen Wu Hong Li Chunling Zhang Lijing Cheng Zhaoqin Li Chaohui Sun Jianping Xu Dake Chen Fei Chai | 2023 | Acta Oceanologica Sinica2023，42，2： | 0 |
| 11 | Corticosteroid-resistant Sweet’s syndrome as the first manifestation of myelodysplastic/myeloproliferative neoplasm-unclassifiable:a case report显示文摘A middle-aged man was diagnosed with myelodysplastic/myeloproliferative neoplasm-unclassifiable(MDS/MPN-U),with severe and extensive corticosteroid-resistant Sweet’s syndrome(SS)as the first manifestation,with evidence of clinical manifestations,pathological description,and laboratory evaluation.The skin lesions continued to spread despite treatment with systemic corticosteroids but were successfully treated with intravenous immunoglobulin(IVIG). | Lina Pan Jingru Zhang Peng Li Chuanli Zhao Shaolei Zang Min Ji Fei Lu Jingjing Ye Chunqing Zhang Chunyan Ji | 2022 | Emergency and Critical Care Medicine2022，2，4： | 0 |
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