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| 1 | Potential use of serum HBV RNA in antiviral therapy for chronic hepatitis B in the era of nucleos(t)ide analogs显示文摘 | Fengmin Lu Jie Wang Xiangmei Chen Dongping Xu Ningshao Xia | 2017 | Frontiers of Medicine2017，11，4： | 28 |
| 2 | A Xanthomonas oryzae pv. oryzae effector, Xop R, associates with receptor-like cytoplasmic kinases and suppresses PAMP-triggered stomatal closure显示文摘Receptor-like kinases(RLKs) play important roles in plant immunity signaling; thus, many are hijacked by pathogen effectors to promote successful pathogenesis. Xanthomonas oryzae pv. oryzae(Xoo) is the causal agent of rice leaf blight disease. The strain PXO99 A has 18 non-TAL(transcription activation-like) effectors; however, their mechanisms of action and host target proteins remain largely unknown. Although the effector XopR from the Xoo strain MAFF311018 was shown to suppress PAMP-triggered immune responses in Arabidopsis, its target has not yet been identified. Here, we show that PXO99 A XopR interacts with BIK1 at the plasma membrane. BIK1 is a receptor-like cytoplasmic kinase(RLCK) belonging to the RLK family of proteins and mediates PAMP-triggered stomatal immunity. In turn, BIK1 phosphorylates XopR. Furthermore, XopR suppresses PAMP-triggered stomatal closure in transgenic Arabidopsis expressing XopR. In addition, XopR is able to associate with RLCKs other than BIK1. These results suggest that XopR likely suppresses plant immunity by targeting BIK1 and other RLCKs. | Shuangfeng Wang Jianhang Sun Fenggui Fan Zhaoyun Tan Yanmin Zou Dongping Lu | 2016 | Science China(Life Sciences)2016，59，9： | 6 |
| 3 | Complementation of Wild-Type and Drug-Resistant Hepatitis B Virus Genomes to Maintain Viral Replication and Rescue Virion Production under Nucleos(t)ide Analogs显示文摘As the open reading frames of hepatitis B virus(HBV)genomes are overlapping,resistance mutations(MTs)in HBV polymerase may result in stop codon MTs in hepatitis B surface proteins,which are usually detected as a mixed population with wild-type(WT)HBV.The question was raised how the coexistence of nucleos(t)ide analogs(NAs)resistance MTs and WT sequences affects HBV replication.In the present study,HBV genomes with frequently detected reverse transcriptase(RT)/surface truncation MTs,rtA181T/sW172^*,rtV191I/sW182^*and rtM204I/sW196^*,were phenotypically characterized alone or together with their WT counterparts in different ratios by transient transfection in the absence or presence of Nas.In the absence of Nas,RT/surface truncation MTs impaired the expression and secretion of HBV surface proteins,and had a dose-dependent negative effect on WT HBV virion secretion.However,in the presence of Nas,coexistence of MTs with WT maintained viral replication,and the presence of WT was able to rescue the production of MT HBV virions.Our findings reveal that complementation of WT and MT HBV genomes is highly effective under drug treatment. | Chunchen Wu Baolin Li Xiaoyong Zhang Kaitao Zhao Yingshan Chen Yifei Yuan Yan Liu Rongjuan Chen Dongping Xu Xinwen Chen Mengji Lu | 2019 | Virologica Sinica2019，34，4： | 4 |
| 4 | A revised species population estimate for the Bar-headed Goose(Anser indicus)显示文摘Background: The Bar-headed Goose(Anser indicus) is a species that relies heavily on the plateau wetlands of Asia and whose population was thought to be declining. Over the past decade, south-central Tibet, one of the most important wintering grounds, supported large numbers of Bar-headed Geese, but the population had not been regularly monitored in this area.Methods: We surveyed wintering Bar-headed Geese along the Yarlung Zangbo, Lhasa and Nyang Qu rivers, the three major river valleys and their tributaries in south-central Tibet in January 2014 and recorded their location, flock size and habitat utilization. Based on these data and the latest wintering counts elsewhere, we revised the population estimate for this species.Results: We recorded more than 67,000 Bar-headed Geese in south-central Tibet during January 2014. By geographic area, the geese were most abundant in the Lhasa River valley(38.5%) and the Nyang Qu River valley(31.0%), and by administrative division in Lhunzhub(27.2%) and Shigatse(26.7%). Bar-headed Geese were most often observed feeding in winter wheat fields and ploughed fields, resting on pastureland and marshes. The approximate number of 67,000 geese recorded in Tibet is more than four times the estimate of 1993 for the same region and exceeds the most recent world population estimate of 52,000–60,000. Based on our work in Tibet and the latest wintering counts available from other areas, we revised the estimated population size of this species to 97,000–118,000.Conclusions: Our result reveals a remarkable increase in the number of Bar-headed Geese wintering in south-central Tibet. This population increase most likely stems from a proliferation of cropland and especially winter wheat fields in south-central Tibet. This habitat improvement may also cause short-stopping of the Bar-headed Goose and thus reduce mortality of the geese that would otherwise undertake a somewhat daunting trans-Himalayan migration. | Dongping Liu Guogang Zhang Fengshan Li Tian Ma Jun Lu Fawen Qian | 2017 | Chinese Birds2017，，1： | 4 |
| 5 | 地铁施工前邻近砌体建筑物的结构安全性分析显示文摘为确保地铁施工期间邻近建筑物的安全使用,在综合考虑邻近建筑物使用现状、相应规范和受力特点的基础上,运用位移反分析和有限元方法对其进行结构安全分析,并据此确定邻近建筑物变形控制指标。在某地铁车站附属结构施工前,应用该方法对2栋邻近砌体结构建筑物的安全性分析表明:当差异沉降小于10mm时,建筑物上部结构和基础底板能够满足正常使用的要求,根据两栋建筑物分别已有6.59和7.01mm的差异沉降现状,给出2栋建筑物沿既有最大倾斜方向的允许新增差异沉降控制值分别为3和2mm。依此标准,建筑物在附属结构施工结束后结构完好,验证了该工前安全性分析方法的合理性。 | Qin, Dongping He, Ping Zhao, Yongzheng Li, Lu | 2012 | 中国铁道科学2012，，4： | 2 |
| 6 | Towards an all-vanadium redox flow battery with higher theoretical volumetric capacities by utilizing the VO^2+/V^3+ couple显示文摘An all-vanadium redox flow battery with V(IV)as the sole parent active species is developed by accessing the VO^(2+)/V^(3+)redox couple.These batteries,referred to as V4RBs,possess a higher theoretical volumetric capacity than traditional VRBs.Copper ions were identified as an effective additive to boost the battery performance. | Wentao Duan Bin Li Dongping Lu Xiaoliang Wei Zimin Nie Vijayakumar Murugesan James P. Kizewski Aaron Hollas David Reed Vincent Sprenkle Wei Wang | 2018 | Journal of Energy Chemistry2018，27，5： | 2 |
| 7 | Population dynamics and habitat use of the Black-necked Crane (Grus nigricollis) in the Yarlung Tsangpo River basin, Tibet, China显示文摘Background:The Black-necked Crane (Grus nigricollis)is an internationally threatened crane living on the plateau, mainly in winter, in the Yarlung Tsangpo River basin in Tibet,western China. In the past five years,some economic development projects have been conducted in this area,posing potential threats to the wintering populations of the cranes and their habitats. Therefore, the current population dynamics of wintering Black-necked Cranes and habitat suitability in the Yarlung Tsangpo River basin were investigated. Methods: Twenty counties were surveyed using the line transect method in December 2017 and January 2018, and we recorded the location,flock size,number of individuals,habitat types and presence of human disturbance in which they occurred.We compared the results from the middle wintering period in this survey with those from 2014. Results: The highest number of cranes recorded was 8291,and the results showed that the cranes were mainly distributed in Lhaze, Namling, Samzhubze, and Lhunzub.A total of 577 and 495 flocks were recorded in the early and middle wintering periods, respectively. In the early wintering period,there were signi ficant differences in the number of individuals across the di fferent habitats,with crop stubble land and plowed land representing more than 30% of the total habitat utilization.In the middle wintering period, there were also signi ficant differences in the number of individuals, and the utilization of crop stubble land represented over 60% of the total. Conclusions: Wintering Black-necked Cranes mainly fed on spilled grains in stubble habitat after harvest. In the middle wintering period, some of the farmlands were plowed and irrigated,which resulted in food shortages in these areas,and the cranes tended to gather in mixed flocks of large size instead of as a single family.There were still considerable regional wintering populations decreases in Quxu,Nedong,and Sakya in 2018 compared with 2014,and these decreases were mainly due to some recently emerging threats,including farmlands being converted into areas of greenhouse cultivation,highway and railway construction, river dredging,the rapid development of the manufacturing and mining industries,and the lack of protection of important wintering sites. | Ru Jia Tian Ma Fengjiang Zhang Guogang Zhang Dongping Liu Jun Lu | 2019 | Avian Research2019，10，3： | 2 |
| 8 | Prognostic factors and recurrence of hepatitis B-related hepatocellular carcinoma after argon-helium cryoablation: a prospective study显示文摘 | Chunping Wang Yinying Lu Yan Chen Yongyi Feng Linjing An Xinzhen Wang Shuhui Su Wenlin Bai Lin Zhou Yongping Yang Dongping Xu | 2009 | Clinical & Experimental Metastasis2009，，7： | 1 |
| 9 | Gene mapping of a new coat mutation in mouse显示文摘Gene mapping of a mouse coat mutation has been investigated. First, 100 10-bp random primers were used to amplify DNA, but the mutation could not be located by this method because there were no correlation between the amplified products and coat phenotypes. Second, by using ldh1 , Car2, Mup1 , Pgb1 , Hbb, Es1O, Es1, Mod1, Gdc1 , Ce2, Es3 as genetic markers, linkage test crosses (two-point test) consisting of intercrossing uncovered BALB/c mice (homozygotes) to CBA/N and C57BL/6 mice with normal hair and backcrossing the heterozygotes of the F1 to the uncovered BALB/c mice were made. It was soon evident that the mutation was linked to Es3 on chromosome 11. Furthermore, three-point test was made by using Es3 and D11 Mit8 (a microsatellite DNA) as genetic markers. The result showed that the mutation was linked to Es3 with the percentage recombination of (7.89 ± 2.19) %, and linked to D11Mit8 with the percentage recombination of (26.30 ± 3.57)%. The percentage recombination between Es3 and D11Mit8 was | Shanru Li Dongping Wang Hong Lan Wenyan Zhang Baosheng Ge Jiqing Li Cuie Wang Yifan Lu Yanyan Shi Runfang Li | 1999 | Chinese Science Bulletin1999，44，13： | 1 |
| 10 | Prognostic factors and recurrence of hepatitis B-related hepatocellular carcinoma after argon-helium cryoablation: a prospective study显示文摘 | Chunping Wang Yinying Lu Yan Chen Yongyi Feng Linjing An Xinzhen Wang Shuhui Su Wenlin Bai Lin Zhou Yongping Yang Dongping Xu | 2009 | Clinical & Experimental Metastasis2009，，7： | 1 |
| 11 | Dielectric Properties and Sintering Characteristics of CaTiO3-(Li1/2Nd1/2)TiO3 Ceramics显示文摘 | Xiangjun Lu Qiang Li Dongping Yang | 2005 | Journal of Electroceramics2005，，1： | 1 |
| 12 | FERONIA receptor kinase pathway suppresses abscisic acid signaling in Arabidopsis by activating ABI2 phosphatase显示文摘 | Feng Yu Lichao Qian Candida Nibau Qiaohong Duan Daniel Kita Kathryn Levasseur Xiaoqian Li Changqing Lu Hui Li Congcong Hou Legong Li Bob B. Buchanan Liangbi Chen Alice Y. Cheung Dongping Li Sheng Luan | 2012 | Proceedings of the National Academy of Sciences2012，，36： | 1 |
| 13 | Direct ubiquiti- nation of pattern recognition receptor FLS2 attenuates plant in- nate immunity显示文摘 | Lu Dongping Lin Wenwei Gao Xiquan | 2011 | Science2011，332，6036： | 1 |
| 14 | Hydrothermal synthesis of LiMn204/C composite as acathode for rechargeable lithium-ion battery with excellent rate capacity显示文摘 | YUE Hongjun HUANG Xingkang LU Dongping | 2009 | Electrochimiea Acta2009，54，23： | 1 |
| 15 | Clinical Features of Severe Tsutsugamushi Disease Complicated with Hemophagocytic Lymphohistiocytosis显示文摘The article discusses a case of severe tsutsugamushi disease complicated with hemophagocytic syndrome in Guangdong Maternal and Child Health Hospital and concludes that blood purification technology has significant therapeutic effect among children with severe HLH complicated with multiple organ dysfunction. | Linglong Lu Hainan Xu Dongping Huang Shumei Peng | 2021 | Proceedings of Anticancer Research2021，5，5： | 0 |
| 16 | Quantification of disaster resilience in civil engineering:A review显示文摘Resistance to unexpected disasters and rapid post-disaster recovery(i.e.,disaster resilience)of cities are extremely necessary owing to the concentrated risk of urbanization.Resilience quantification can adequately reflect the capacity of a city to withstand disasters.Many existing studies have focused on and proposed several frameworks on the quantitative measures of disaster resilience,and the corresponding research objects include different types of disasters(e.g.,earthquake,hurricane,flood,and fire),various domains(e.g.,engineering,social,and economic),and multiple levels(e.g.,city,community,and building).Among these research objects,studies on seismic resilience in civil engineering are relatively comprehensive.Specifically,studies on resilience in civil engineering have paid significant attention to the dynamics of engineering facilities and the engineering-related social and economic functions,including city-scale engineering,social,and economic functionalities,and essential functionalities of building,transportation,lifeline,and nonphysical subsystems of a city.Consequently,based on the review of resilience studies carried out in recent years,the framework and specifications for the quantification of disaster resilience of civil engineering systems subjected to earthquakes and other unexpected disasters are elaborated.Methods of disaster resilience assessment of cities and the corresponding subsystems are discussed.Furthermore,several case studies are reviewed,and resilience limit-state analyses of communities and buildings are performed. | Xinzheng Lu Wenjie Liao Dongping Fang Kaiqi Lin Yuan Tian Chi Zhang Zhe Zheng Pengju Zhao | 2020 | Journal of Safety Science and Resilience2020，1，1： | 0 |
| 17 | A steady composite molecular anode Ru1/MWCNTsCOOH/GC for robust catalytic water oxidation显示文摘Development of efficient molecular devices for overall water splitting has always been a hotspot of research to realize clean and sustainable energy conversion. In the case, long-term durability of molecular devices is a crucial factor to determine their practical application. Here, an efficient composite molecular anode was assembled by immobilization of charge-neutral mononuclear Ru1 complex on COOHfunctionalized multiwalled carbon nanotubes(MWCNTs COOH) sticking on a glassy carbon(GC) electrode(Ru1/MWCNTsCOOH/GC). The prepared hybrid anode showed a low onset overpotential of only 380 mV for electrocatalytic water oxidation. Moreover, the anode displayed a steady catalytic current density of1.25 mA/cm^2 for more than 5 h at the overpotential of 580 m V, a high TON of 186000(5 h), a TOF of10.3 s-1 and a faradic efficiency of 96%, indicating the significant efficiency and extremely durability.The excellent durability of the molecular anode should be attributed to the key charge-neutral catalytic intermediates(Ru1 ad) of the catalytic step and the two long flexible carbon chains of the catalyst. | Yan Gao Yu Wei Zhongkai Lu Xuyang Chen Dongping Wang | 2019 | Journal of Energy Chemistry2019，28，8： | 0 |
| 18 | Special issue: City and infrastructure engineering and management显示文摘Urban and infrastructure systems are essential for the sustainable development of cities worldwide because they play a fundamental role in the provision of essential services,such as transport,communication,and health care,to support the basic livelihood of residents. | Weihe HUANG Chunfang LU Dongping FANG | 2021 | Frontiers of Engineering Management2021，8，1： | 0 |
| 19 | Efficacy of intelligent diagnosis with a dynamic uncertain causality graph model for rare disorders of sex development显示文摘Disorders of sex development(DSD)are a group of rare complex clinical syndromes with multiple etiologies.Distinguishing the various causes of DSD is quite difficult in clinical practice,even for senior general physicians because of the similar and atypical clinical manifestations of these conditions.In addition,DSD are difficult to diagnose because most primary doctors receive insufficient training for DSD.Delayed diagnoses and misdiagnoses are common for patients with DSD and lead to poor treatment and prognoses.On the basis of the principles and algorithms of dynamic uncertain causality graph(DUCG),a diagnosis model for DSD was jointly constructed by experts on DSD and engineers of artificial intelligence.“Chaining”inference algorithm and weighted logic operation mechanism were applied to guarantee the accuracy and efficiency of diagnostic reasoning under incomplete situations and uncertain information.Verification was performed using 153 selected clinical cases involving nine common DSD-related diseases and three causes other than DSD as the differential diagnosis.The model had an accuracy of 94.1%,which was significantly higher than that of interns and third-year residents.In conclusion,the DUCG model has broad application prospects as a computer-aided diagnostic tool for DSDrelated diseases. | Dongping Ning Zhan Zhang Kun Qiu Lin Lu Qin Zhang Yan Zhu Renzhi Wang | 2020 | Frontiers of Medicine2020，14，4： | 0 |
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