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| 1 | MEKK1, MKK1/MKK2 and MPK4 function together in a mitogen-activated protein kinase cascade to regulate innate immunity in plants显示文摘激活 Mitogen 的蛋白质 kinase (MAPK ) 串联在调整植物起重要作用天生的有免疫力的回答。在到为有组成的防卫回答的异种的搜索的一幅基因屏幕,我们识别了展出房间死亡和组成的防卫回答的 mpk4 和 mekk1 的多重等位基因。双分子的荧光互补(BiFC ) 分析证明 MPK4 和 MEKK1 与 MKK1 和 MKK2 交往,二密切相关的 MAPK kinases。mkk1 和 mkk2 单身者异种植物没有明显的变异的显型。测试 MKK1 和 MKK2 是否冗余地工作, mkk1 mkk2 两倍异种被产生。mkk1 mkk2 两倍变异的植物在幼苗舞台和幼苗致命性显型死是温度依赖者。类似于 mpk4 和 mekk1 异种,两倍变异的幼苗积累的 mkk1 mkk2 H2O2 高级,显示自发的房间死亡,联系的组成地快速的致病(PR ) 基因和展览病原体抵抗。另外,由 flg22 的 MPK4 的激活在 mkk1 mkk2 被损害两倍异种,在地图 kinase 串联和 MPK4 和 MEKK1 建议那 MKK1 和 MKK2 功能否定地在植物调整天生的有免疫力的回答。 | Minghui Gao Jinman Liu Dongling Bi Zhibin Zhang Fang Cheng2, Sanfeng Chen Yuelin Zhang | 2008 | Cell Research2008，18，12： | 37 |
| 2 | Climate and litter C/N ratio constrain soil organic carbon accumulation显示文摘Soil organic carbon(SOC) plays critical roles in stabilizing atmospheric CO2 concentration, but the mechanistic controls on the amount and distribution of SOC on global scales are not well understood. In turn, this has hampered the ability to model global C budgets and to find measures to mitigate climate change. Here, based on the data from a large field survey campaign with 2600 plots across China’s forest ecosystems and a global collection of published data from forested land, we find that a low litter carbon-to-nitrogen ratio(C/N) and high wetness index(P/PET, precipitation-to-potentialevapotranspiration ratio) are the two factors that promote SOC accumulation, with only minor contributions of litter quantity and soil texture. The field survey data demonstrated that high plant diversity decreased litter C/N and thus indirectly promoted SOC accumulation by increasing the litter quality. We conclude that any changes in plant-community composition, plant-species richness and environmental factors that can reduce the litter C/N ratio, or climatic changes that increase wetness index, may promote SOC accumulation. The study provides a guideline for modeling the carbon cycle of various ecosystem scales and formulates the principle for land-based actions for mitigating the rising atmospheric CO2 concentration. | Guoyi Zhou Shan Xu Philippe Ciais Stefano Manzoni Jingyun Fang Guirui Yu Xuli Tang Ping Zhou Wantong Wang Junhua Yan Gengxu Wang Keping Ma Shenggong Li Sheng Du Shijie Han Youxin Ma Deqiang Zhang Juxiu Liu Shizhong Liu Guowei Chu Qianmei Zhang Yuelin Li Wenjuan Huang Hai Ren Xiankai Lu Xiuzhi Chen | 2019 | National Science Review2019，6，4： | 21 |
| 3 | Authentic compound-free strategy for simultaneous determination of primary coumarins in Peucedani Radix using offline high performance liquid chromatography–nuclear magnetic resonance spectroscopy–tandem mass spectrometry显示文摘Herein, a strategy is proposed for the simultaneous determination of primary coumarins in Peucedani Radix(Chinese name: Qianhu). The methodology consists of three consecutive steps: 1) Semi-preparative LC in combination with a home-made automated fraction collection module to fragment the universal metabolome standard into ten fractions(Frs. I–X); 2) LC–accurate MS/MS and quantitative1 H NMR spectroscopy conducted in parallel to acquire the qualitative and quantitative data of each fraction; 3) Robust identification and quantification of components by use of LC coupled to multiple reaction monitoring. In this final step, the most significant fractions(Frs. III–X) were pooled to serve as the pseudo-mixed standard solution. Meticulous online parameter optimization was performed to obtain the optimal parameters, including ion transitions and collision energies. Concerns were particularly paid onto pursuing the parameters being capable of monitoring regiospecific isomers, notably praeruptorin E vs. 3′-isovaleryl-4′-angeloylkhellactone. The quantitative performance of the method was validated according to diverse assays. Eleven primary coumarins(1–11) were unambiguously identified and absolutely quantified, even though no external reference compound was used. Above all, the integrated strategy not only provides a feasible pipeline for the quality assessment of Peucedani Radix, but more importantly, shows the potential for authentic compound-free quantitative evaluation of traditional Chinese medicines. | Yao Liu Qingqing Song Wenjing Liu Peng Li Jun Li Yunfang Zhao Liang Zhang Pengfei Tu Yitao Wang Yuelin Song | 2018 | Acta Pharmaceutica Sinica B2018，8，4： | 6 |
| 4 | Splicing of Receptor-Like Kinase-Encoding SNC4 and CERK1 is Regulated by Two Conserved Splicing Factors that Are Required for Plant Immunity显示文摘植物免疫者受体属于像受体的 kinase (RLK ) 家庭在微生物引起的病原体的识别和下游的防卫回答的激活起重要作用。Arabidopsis 变异的 snc4-1D 在 RLK SNC4 包含一个 gain-of-function 变化(NPR1-1 的 SUPPRESSOR, CONSTITUTIVE4 ) ,它导致防卫回答的组成的激活。snc4-1D 的 suppressor 异种的分析鉴别二保存了拼接的因素, SUA (ABI3-5 的 SUPPRESSOR ) 和 RSN2 (为 SNC4-1D 2 要求了) ,那在 snc4-1D 为组成的防卫回答被要求。在 sua 和 rsn2 异种,拼接的 SNC4 被改变, SNC4 抄本的数量被减少。进一步的分析证明 SUA 和 RSN2 也为 CERK1 (几丁质 ELICITOR 受体 KINASE1 ) 的合适的拼接被要求,它编码为几丁质作为受体工作的另一 RLK。在 sua 和 rsn2 异种,由几丁质的反应的氧种类的正式就职被减少并且非病原的细菌 Pseudomonas syringae pv。西红柿 DC3000hrcC 比在野类型的植物成长到更高的 titers。我们的学习建议拼接的 pre-mRNA 在植物免疫的规定起重要作用由 RLK SNC4 和 CERK1 调停了。 | Zhibin Zhang Yanan Liu Pingtao Ding Yan Li Qing Kong Yuelin Zhang | 2014 | Molecular Plant2014，7，12： | 5 |
| 5 | Separation and Manipulation of Rare-earth Oxide Particles by Dielectrophoresis显示文摘A challenge in chemical engineering is the separation and purification of rare-earth elements and their compounds. We report the design and manufacture of a dielectrophoresis(DEP) microchip of microelectrode arrays. This microchip device is constructed in order to use DEP to capture micro-particles of rare-earth oxides in petro-leum. Dielectrophoretic behavior of micro-particles of rare-earth oxides in oil media is explored. The dielectropho-retic effects of particles under different conditions are investigated. It is showed that the prepared microchip is suit-able for use in the investigation of dielectrophoretic responses of the rare-earth oxides in oil media. The factors such as frequency,particle size and valence of rare-earth metal are discussed. When the frequency is fixed,the transla-tion voltage decreases as particle size increases. Lower frequencies are more effective for manipulation of inorganic particles in oil media. Particles of the same rare-earth oxide with different size,as well as particles of different rare-earth oxides,are captured in different regions of the field by regulating DEP conditions. This may be a new method for separation and purification of particles of different rare-earth oxides,as well as classification of particles with different size. | CHEN Huiying LIU Yan ZHANG Heteng YU Le ZHU Yuelin LI Di | 2010 | Chinese Journal of Chemical Engineering2010，18，6： | 4 |
| 6 | Characteristics and Genetic Mechanisms of Overpressure in the Depressions of Bohai Bay Basin, China显示文摘The distribution and genetic mechanisms of abnormal pressures in the Bohai Bay Basin were systematically analyzed. Abnormal pressures are widely developed in the Bohai Bay Basin,primarily in the Paleogene E_(2s_4),E_(2s_3),E_(s_1),and Ed formations. From the onshore area of the Bohai Bay Basin to the center of the Bozhong area,the top depth of the overpressured zone in each depression increases gradually,the overpressured strata in each depression gradually move to younger formations,and the pressure structure successively alters from single-bottom- overpressure to doublebottom-overpressure and finally to double-top-overpressure. The distribution of overpressured area is consistent with the sedimentary migration controlled by the tectonic evolution of the Bohai Bay Basin,which is closely related to the hydrocarbon-generation capability of active source rocks. The overpressured strata are consistent with the source-rock intervals in each depression; the top of the overpressured zone is synchronous with the hydrocarbon generation threshold in each depression; the hydrocarbon generation capability is positively correlated with the overpressure magnitude in each formation. Undercompaction was the main mechanism of overpressure for depressions with fluid pressure coefficients less than 1.2,whereas hydrocarbon generation was the main mechanism for depressions with fluid pressure coefficients greater than 1.5. | LIU Hua JING Chen JIANG Youlu SONG Guoqi YU Qianqian FENG Yuelin | 2016 | Acta Geologica Sinica(English Edition)2016，90，6： | 4 |
| 7 | C:N:P stoichiometry of Ericaceae species in shrubland biomes across Southern China:influences of climate,soil and species identity显示文摘Aims Carbon(C),nitrogen(N)and phosphorus(P)stoichiometry strongly affect functions and nutrient cycling within ecosystems.However,the related researches in shrubs were very limited.In this study,we aimed to inves-tigate leaf stoichiometry and its driving factors in shrubs,and whether stoichiometry significantly differs among closely related species.Methods We analyzed leaf C,N and P concentrations and their ratios in 32 species of Ericaceae from 161 sites across southern China.We examined the relationships of leaf stoichiometry with environmen-tal variables using linear regressions,and quantified the interactive and independent effects of climate,soil and species on foliar stoi-chiometry using general linear models(GLM).Important Findings The foliar C,N and P contents of Ericaceae were 484.66,14.44 and 1.06 mg g−1,respectively.Leaf C,N and P concentrations and their ratios in Ericaceae were significantly related with latitude and altitude,except the N:P insignificantly correlated with latitude.Climate(mean annual temperature and precipitation)and soil properties(soil C,N and P and bulk density)were significantly influenced element stoichiom-etry.The GLM analysis showed that soil exerted a greater direct effect on leaf stoichiometry than climate did,and climate affected leaf traits mainly via indirect ways.Further,soil properties had stronger influ-ences on leaf P than on leaf C and N.Among all independent factors examined,we found species accounted for the largest proportion of the variation in foliar stoichiometry.These results suggest that species can largely influence foliar stoichiometry,even at a lower taxonomic level. | Qiang Zhang Qing Liu Huajun Yin Chunzhang Zhao Lin Zhang Guoying Zhou Chunying Yin Zhijun Lu Gaoming Xiong Yuelin Li Jiaxiang Li Wenting Xu Zhiyao Tang Zongqiang Xie | 2019 | Journal of Plant Ecology2019，12，2： | 4 |
| 8 | Let-7b-5p regulates proliferation and apoptosis in multiple myeloma by targeting IGF1R显示文摘多重骨髓瘤(公里) 全球是从 hematological 恶意的死亡的最普通的原因,并且最近的研究表明了 let-7b-5p 能在 tumorigenesis 起一个禁止的作用。然而,在公里的 let-7b-5p 的角色仍然保持不清楚。这研究的目的是阐明 let-7b-5p 在公里由充当肿瘤 suppressor 的分子的机制。这里,量的即时聚合酶链反应结果证明 let-7b-5p 的表示显著地在公里纸巾和公里房间线(RPMI-8226 和 U266 房间) 被减少。而且, let-7b-5p 的在表示上显著地压制了 RPMI-8226 房间增长并且导致了 S/G2 房间周期拘捕和 apoptosis。酶记者试金结果证明(IGF1R ) 像胰岛素的生长因素受体 1 被 let-7b-5p 否定地在 post-transcriptional 水平调整。在 RPMI-8226 房间的 IGF1R 的 mRNA 和蛋白质层次由 let-7b-5p 是下面调整的。而且, let-7b-5p 禁止者改变的房间显型能被 IGF1R silencing (si-IGF1R ) 救。一起拿,我们的结果证明 let-7b-5p 在公里作为肿瘤 suppressor 工作,建议那 let-7b-5p 可以是为公里的一个潜在的治疗学的目标。 | Honghai Xu Cong Liu Yuelin Zhang Xiong Guo Zongzhi Liu Zhenqun Luo Yanhai Chang Shizhang Liu Zhengming Sun Xiaoqing Wang | 2014 | Acta Biochimica et Biophysica Sinica2014，46，11： | 4 |
| 9 | High-Performance and Hysteresis-Free Perovskite Solar Cells Based on Rare-Earth-Doped SnO_(2) Mesoporous Scaffold显示文摘Tin oxide(SnO_(2)),as electron transport material to substitute titanium oxide(TiO_(2))in perovskite solar cells(PSCs),has aroused wide interests.However,the performance of the PSCs based on SnO_(2) is still hard to compete with the TiO_(2)-based devices.Herein,a novel strategy is designed to enhance the photovoltaic performance and long-term stability of PSCs by integrating rare-earth ions Ln^(3+)(Sc^(3+),Y^(3+),La^(3+))with SnO_(2) nanospheres as mesoporous scaffold.The doping of Ln promotes the formation of dense and large-sized perovskite crystals,which facilitate interfacial contact of electron transport layer/perovskite layer and improve charge transport dynamics.Ln dopant optimizes the energy level of perovskite layer,reduces the charge transport resistance,and mitigates the trap state density.As a result,the optimized mesoporous PSC achieves a champion power conversion efficiency(PCE)of 20.63%without hysteresis,while the undoped PSC obtains an efficiency of 19.01%.The investigation demonstrates that the rare-earth doping is low-cost and effective method to improve the photovoltaic performance of SnO_(2)-based PSCs. | Qiyao Guo Jihuai Wu Yuqian Yang Xuping Liu Zhang Lan Jianming Lin Miaoliang Huang Yuelin Wei Jia Dong Jinbiao Jia Yunfang Huang | 2019 | Research2019，，1： | 3 |
| 10 | Stability and diffusion properties of self-interstitial atoms in tungsten:a first-principles investigation显示文摘基于密度功能理论采用一个第一原则的方法,我们系统地在钨(W) 调查自我空隙的原子(SIA ) 的结构,稳定性和散开。The111 哑铃被显示是有 9.43 eV 的形成精力的最稳定的 SIA 缺点配置。所在地的旋转模式罐头被相当软的漂浮机制和一个下坡的飘移散开过程分别地从 110 哑铃描述到 111 哑铃并且从 001 哑铃到 110 哑铃。在跳接近附近的地点的不同 SIA 配置之中, 111 哑铃更更好与 0.004 eV 的一个低得多的精力障碍直接移居到 first-nearest-neighboring 地点。这些结果作为在熔化 Tokamak 面对材料的候选人血浆为 W 提供一本有用参考书。 | CHEN Long LIU YueLin ZHOU HongBo JIN Shuo ZHANG Ying LU GuangHong | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，4： | 2 |
| 11 | Diffusion behaviors of hydrogen isotopes in niobium from first-principles显示文摘We investigate diffusion behaviors of hydrogen(H),deuterium(D),and tritium(T) in bulk niobium(Nb) using first-principles method.The diffusion energy barrier with quantum-correction has been calculated to be 0.12 eV,which is in good agreement with the experimental value of ~0.106 eV.According to diffusion theory presented by Wert and Zener,the diffusion pre-exponential factors of H,D,and T are shown to be 7.74×10-8m 2 s-1,5.47×10-8 m 2 s-1 and 4.48×10-8 m 2 s-1,respectively.These results are also in quantitative agreement with the corresponding experimental values. | LU Wei GAO AnYuan LIU YueLin DAI ZhenHong | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，12： | 2 |
| 12 | Phase-and epidemic region-adjusted estimation of the number of coronavirus disease 2019 cases in China显示文摘The outbreak of the coronavirus disease 2019 in China was first reported in Wuhan in December 2019 and gradually spread to other areas in China.After implementation of prevention and control measures,the estimation of the epidemic trend is needed.A phase-and region-adjusted SEIR model was applied for modeling and predicting the number of cases in Wuhan,Hubei Province and regions outside Hubei Province in China.The estimated number of infections could reach its peak in late February 2020 in Wuhan and Hubei Province,which is 55303–84520 and 83944–129312,respectively,while the epidemic peaks in regions outside Hubei Province in China could appear on February 13,2020 with the estimated 13035–19108 cases.According to the estimation,the outbreak would abate in March and April all over China.Current estimation provided evidence for planned work resumption under stringent prevention and control in China to further support the fight against the epidemic.Nevertheless,there is still possibility of the second outbreak brought by the work resumption and population migration,especially from Hubei Province and high intensity cities outside Hubei Province.Strict prevention and control measures still need to be considered in the regions with high intensity of epidemic and densely-populated cities. | Ruijie Chang Huwen Wang Shuxian Zhang Zezhou Wang Yinqiao Dong Lhakpa Tsamlag Xiaoyue Yu Chen Xu Yuelin Yu Rusi Long Ning-Ning Liu Qiao Chu Ying Wang Gang Xu Tian Shen Suping Wang Xiaobei Deng Jinyan Huang Xinxin Zhang Hui Wang Yong Cai | 2020 | Frontiers of Medicine2020，14，2： | 2 |
| 13 | Structural basis for BIRl-mediated negative regulation of plant immunity显示文摘 | Cuiyan Ma Yanan Liu Bing Bai Zhifu Han Jiao Tang Heqiao Zhang Hoda Yaghmaiean Yuelin Zhang Jijie Chai | 2017 | Cell Research2017，27，12： | 2 |
| 14 | Single Cu nanowire assembled by microdroplet dielectrophoresis on ultrahigh tensible microelectrodes显示文摘At present,study on dynamic tensile properties and atomic chain fabrication of single nanowire,for understanding its dynamic tensile properties and unique physical properties of atomic chain to fabricate atom scale devices,is one of frontier research issues in nanoscale science.However,how to assemble single nanowire on a tensible microstructure becomes one of the most difficult problems,which severely restricts the development of this research field.In this paper,after the ultrahigh tensible microelectrode chip is fabricated by MEMS technology,hexamethyldisilazane is utilized to improve hydrophobicity of the chip,and then a microdroplet dielectrophoresis experimental platform and technology is developed to assemble single nanowire on the sensible microelectrode.Experimental results show that accurate and efficient assembly of single Cu nanowire is realized,which contribute greatly to the further research of dynamic tensile properties and atomic chain fabrication.And for guiding the assembly experiments,finite element technology is also utilized to analyze the local microelectro field around the microelectrodes during dieletrophoresis experiments. | Chaolei Huang Hongjiang Zeng Xiaojun Tian Jie Liu Zaili Dong Tie Li Yuelin Wang | 2014 | Chinese Science Bulletin2014，59，5： | 1 |
| 15 | Simultaneous biosorption of cadmium (II) and lead (II) ions by pretreated biomass of Phanerochaete chrysosporium显示文摘 | Qingbiao Li Songtao Wu Gang Liu Xinkai Liao Xu Deng Daohua Sun Yuelin Hu Yili Huang | 2003 | Separation and Purification Technology2003，，1： | 1 |
| 16 | Calcium channels at the center of nucleotide-binding leucine-rich repeat receptor-mediated plant immunity显示文摘Higher plants utilize a variety of immune receptors to recognize pathogens and trigger defense responses.Intracellular nucleotidebinding leucine-rich repeat receptors(NLRs)are widely used for detecting pathogen effectors(Jones et al.,2016;Zhou and Zhang,2020).NLRs are also present in animals,including mammals。 | Shitou Xia Xueru Liu Yuelin Zhang | 2021 | Journal of Genetics and Genomics2021，48，6： | 1 |
| 17 | Trapping and diffusion behaviors of helium at vacancy in iron from first principles显示文摘We investigate the structure,trapping,and diffusion behaviors of helium(He) at vacancy in a Fe single crystal using first-principles simulations.Vacancy with more space can provide the lower electron density region for He binding in comparison with intrinsic Fe,causing He to diffuse into the vacancy inner easily.We provide the quantitative microscopic studies related to the atomic-level thermo-kinetic trapping processes.Moreover,such physical viewpoint can be applied to other vacancy-like defects such as vacancy clusters,void and grain boundaries which can open a space with reduced electron density region to increase He binding in metals and metal alloys. | LIU YueLin SHI WenPu | 2013 | Science China(Physics,Mechanics & Astronomy)2013，56，6： | 1 |
| 18 | Application and Development of Biosensors显示文摘As a new kind of analytical instrument,the principles,types and characters of biosensors were discussed in this paper.A biosensor is usually composed of a recognition element of biological origin and a physicochemical transducer.The biological element is capable of sensing the presence,activity or concentration of a chemical analyse in solution.The sensing takes place either as a binding event or a biocatalytical event.These interactions produce a measurable change in a solution property,in which the transducer is converted into a quantifiable electrical signal.The principles,types and applications of biosensors in environmental inspection,food production,clinical medicine and military defense were reviewed,and the trends in research were predicated.Furthermore,an attempt had been made to describe the future development directions and prospects. | GAO Yuelin LI Jichang HUO Guicheng LIU Libo | 2008 | Journal of Northeast Agricultural University(English Edition)2008，15，2： | 1 |
| 19 | Production and analysis of intergeneric somatic hybrids between Brassica oleracea and Matthiola incana显示文摘 | Xiaoguang Sheng Fan Liu Yuelin Zhu Hong Zhao Li Zhang Bin Chen | 2008 | Plant Cell Tissue and Organ Culture2008，，1： | 1 |
| 20 | Chinese Physics B显示文摘 | Liu Yuelin Gui Lijiang Jin Shuo | 2012 | 21(9):96 1022012，21，96： | 1 |
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