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| 1 | Latest Progress of the Chinese Meteorological Satellite Program and Core Data Processing Technologies显示文摘In this paper,the latest progress,major achievements and future plans of Chinese meteorological satellites and the core data processing techniques are discussed.First,the latest three FengYun(FY)meteorological satellites(FY-2H,FY-3D,and FY-4A)and their primary objectives are introduced Second,the core image navigation techniques and accuracies of the FY meteorological satellites are elaborated,including the latest geostationary(FY-2/4)and polar-orbit(FY-3)satellites.Third,the radiometric calibration techniques and accuracies of reflective solar bands,thermal infrared bands,and passive microwave bands for FY meteorological satellites are discussed.It also illustrates the latest progress of real-time calibration with the onboard calibration system and validation with different methods,including the vicarious China radiance calibration site calibration,pseudo invariant calibration site calibration,deep convective clouds calibration,and lunar calibration.Fourth,recent progress of meteorological satellite data assimilation applications and quantitative science produce are summarized at length.The main progress is in meteorological satellite data assimilation by using microwave and hyper-spectral infrared sensors in global and regional numerical weather prediction models.Lastly,the latest progress in radiative transfer,absorption and scattering calculations for satellite remote sensing is summarized,and some important research using a new radiative transfer model are illustrated. | Peng ZHANG Qifeng LU Xiuqing HU Songyan GU Lei YANG Min MIN Lin CHEN Na XU Ling Sun Wenguang BAI Gang MA Di XIAN | 2019 | Advances in Atmospheric Sciences2019，36，9： | 26 |
| 2 | Primary closure versus T-tube drainage in laparoscopic common bile duct exploration: a meta-analysis of randomized clinical trials显示文摘 | Xiangsong Wu Yong Yang Ping Dong Jun Gu Jianhua Lu Maolan Li Jiasheng Mu Wenguang Wu Jiahua Yang Lin Zhang Qichen Ding Yingbin Liu | 2012 | Langenbeck’s Archives of Surgery2012，，6： | 4 |
| 3 | A SNX10/V-ATPase pathway regulates ciliogenesis in vitro and in vivo显示文摘排序 nexins (SNX )phosphoinositide 有约束力的蛋白质在在 vitro 排序各种各样的膜蛋白质被含有,但是在里面他们的 vivo 功能仍然保持大部分未知。我们以前报导 SNX10 是 SNX 家庭基因的一个独特成员因为它在房间举办 vacuolation 活动。我们在这研究由 loss-of-function 试金调查 SNX10 的生物功能并且证明 SNX10 在有教养的房间为主要的睫的形成被要求。在 zebrafish, SNX10 为内脏的机关的左右的 patterning 在 Kupffer 的泡和必需品涉及 ciliogenesis。机械学地, SNX10 与复杂的 V-ATPase 交往并且指向它到 ciliogenesis 被开始的中心体。象 SNX10 一样, V-ATPase 在 vitro 并且在 vivo 调整 ciliogenesis 并且对 SNX10 那么 synergistically 做。我们进一步发现 SNX10 和 V-ATPase 调整 Rab8a 的睫的 trafficking,它是睫的膜扩展的一个批评管理者。这些结果识别为 ciliogenesis 是关键的一条 SNX10/V-ATPase-regulated 小囊的 trafficking 小径,并且表明通过在各种各样的机关的睫形成的规定, SNX10/V-ATPase 在早胚胎的开发期间起一个必要作用。 | Yanqun Chen Bin Wu Liangliang Xu Huapeng Li Jianhong Xia Wenguang Yin Zhuo Li Dawei Shi Song Li Shuo Lin Xiaodong Shu Duanqing Pei | 2012 | Cell Research2012，22，2： | 4 |
| 4 | Study on cellular internalization of poly(vinyldiaminotriazine)-based hydrogen bonding type non-viral transgene vector显示文摘Previously we successfully prepared poly(vinyldiaminotriazine)(PVDT)-based non-viral vectors which complexed plasmid DNA via hydrogen bonding with adenine-thymine base pairs. In this report, surface charges and complex sizes of this system were further examined. The results showed that PVDT-based polymer could cover surface charges of DNA resulting in slightly negative or neutral complexes. It was also found that the complex sizes were governed by two events: the aggregation induced by the insta-bility of neutral particles, and more compact complexes produced by PVDT-based polymers. In the study of cellular uptake, chlorpromazine and filipin Ⅲ were used to inhibit clathrin- and caveolae-me- diated endocytosis, respectively. We found that PVDT-based systems were transported into cells via a non-clathrin, non-caveolae mediated endocytosis. This special process was studied by temperature inhibition and kinetics assays. It was revealed that such a pathway was characterized by (i) a more en-ergy dependent process and (ii) a much slow transfection-effective internalization. | YE GuiXiang CAO ZhiQiang LIN Lin CHEN DaYong LIU WenGuang | 2008 | Chinese Science Bulletin2008，53，15： | 3 |
| 5 | Protective electrode/electrolyte interphases for high energy lithium-ion batteries with p-toluenesulfonyl fluoride electrolyte additive显示文摘High energy density lithium-ion batteries using Ni-rich cathode(such as LiNi0.6Co0.2Mn0.2O2) suffer from severe capacity decay.P-toluenesulfonyl fluoride(pTSF) has been investigated as a novel film-forming electrolyte additive to enhance the cycling performances of graphite/LiNi0.6Co0.2Mn0.2O2 pouch cell.In comparison with the baseline electrolyte,a small dose of pTSF can significantly improve the cyclic stability of the cell.Theoretical calculations together with experimental results indicate that pTSF would be oxidized and reduced to construct protective interphase film on the surfaces of LiNi0.6Co0.2Mn0.2O2 cathode and graphite anode,respectively.These S-containing surface films derived from pTSF effectively mitigate the decomposition of electrolyte,reduce the interphasial impedance,as well as prevent the dissolution of transition metal ions from Ni-rich cathode upon cycling at high voltage.This finding is beneficial for the practical application of high energy density graphite/LiNi0.6Co0.2Mn0.2O2 cells. | Yanxia Che Xiuyi Lin Lidan Xing Xiongcong Guan Rude Guo Guangyuan Lan Qinfeng Zheng Wenguang Zhang Weishan Li | 2021 | Journal of Energy Chemistry2021，30，1： | 3 |
| 6 | Role of polymorphisms of the IGF2 and IGFBP3 genes and risk of gastric carcinoma in China显示文摘 | Gu Jun Li Maolan Dong Ping Lu Jianhua Tan Zhujun Wu Xiangsong Mu Jiasheng Zhang Lin Wu Wenguang Ding Qichen Yang Jiahua Cao Yang Ding Qian Weng Hao Liu Yingbin | 2014 | Chinese Medical Journal2014，，3： | 2 |
| 7 | Effect of Temperature on Gene Expression in the Pearl Oyster Pinctada fucata显示文摘In this study, we examined the effect of elevated temperature on the expression patterns of genes, i.e., nacrein, irr, n16, n19, and hsp70 in the pearl oyster Pinctada fucata. The experiment was carried out at 4 temperatures, i.e., 20℃(ambient, control), 24, 28℃, and 32℃. The expression levels of target genes in P. fucata were assayed at 0, 6, 24, 48, and 96 h via real-time polymerase chain reaction. Results showed that the expression levels of nacrein and irr had no significant variations among different time points below 28℃, but significantly increased over time at 32℃. The expression levels of n16 and n19 did not change markedly at 20℃. The former increased significantly at 6 h and 24 h while the latter substantially decreased during 6–96 h at 24, 28 and 32℃. Among different temperatures, the level of n16 was significantly lower at 20℃ than at other temperatures during 6–96 h, and the level of n19 significantly varied among different temperatures at 48 h and 96 h. The expression level of hsp70 was significantly higher at 32℃ than at 20, 24 and 28℃ at 24 h. These results demonstrated that elevated temperature impacted the physiological processes of P. fucata and potentially influenced its adaptability to thermal stress. | LIU Wenguang HUANG Xie LIN Jianshi HE Maoxian | 2014 | Journal of Ocean University of China2014，13，3： | 2 |
| 8 | Identification of Functional Genetic Variants in Cyclooxygenase-2 and Their Association With Risk of Esophageal Cancer显示文摘 | Xuemei Zhang Xiaoping Miao Wen Tan Baitang Ning Zhihua Liu Yuan Hong Wenguang Song Yongli Guo Xinyu Zhang Yan Shen Boqin Qiang Fred F. Kadlubar Dongxin Lin | 2005 | Gastroenterology2005，，2： | 1 |
| 9 | Identification of Functional Genetic Variants in Cyclooxygenase-2 and Their Association With Risk of Esophageal Cancer显示文摘 | Xuemei Zhang Xiaoping Miao Wen Tan Baitang Ning Zhihua Liu Yuan Hong Wenguang Song Yongli Guo Xinyu Zhang Yan Shen Boqin Qiang Fred F. Kadlubar Dongxin Lin | 2005 | Gastroenterology2005，，2： | 1 |
| 10 | Human reli-ability assessment for medical devices based on failure mode andeffects analysis and fuzzy linguistic theory 显示文摘 | LIN Qinglian WANG Duojin LIN Wenguang | 2014 | Safety Science2014，62，： | 1 |
| 11 | Identification of Functional Genetic Variants in Cyclooxygenase-2 and Their Association With Risk of Esophageal Cancer显示文摘 | Xuemei Zhang Xiaoping Miao Wen Tan Baitang Ning Zhihua Liu Yuan Hong Wenguang Song Yongli Guo Xinyu Zhang Yan Shen Boqin Qiang Fred F. Kadlubar Dongxin Lin | 2005 | Gastroenterology2005，，2： | 1 |
| 12 | A role for p21‐activated kinase 7 in the development of gastric cancer显示文摘 | Jun Gu Keqiang Li Maolan Li Xiangsong Wu Lin Zhang Qichen Ding Wenguang Wu Jiahua Yang Jiasheng Mu Hao Wen Qian Ding Jianhua Lu Yuan Hao Lei Chen Wenjie Zhang Songgang Li Yingbin Liu | 2012 | FEBS J2012，，1： | 1 |
| 13 | Primary closure versus T-tube drainage in laparoscopic common bile duct exploration: a meta-analysis of randomized clinical trials显示文摘 | Xiangsong Wu Yong Yang Ping Dong Jun Gu Jianhua Lu Maolan Li Jiasheng Mu Wenguang Wu Jiahua Yang Lin Zhang Qichen Ding Yingbin Liu | 2012 | Langenbeck’s Archives of Surgery2012，，6： | 1 |
| 14 | Hydrothermal pretreatment of microalgae for production of pyrolytic bio-oil with a low nitrogen content显示文摘 | Zhenyi Du Michael Mohr Xiaochen Ma Yanling Cheng Xiangyang Lin Yuhuan Liu Wenguang Zhou Paul Chen Roger Ruan | 2012 | Bioresource Technology2012，，： | 1 |
| 15 | Ultralow-temperature assisted synthesis of single platinum atoms anchored on carbon nanotubes for efficiently electrocatalytic acidic hydrogen evolution显示文摘Although platinum(Pt) is highly active for hydrogen evolution reaction(HER)[1], it is crucial to explore the effective approach for minimizing the Pt loading amount in the practical application. Herein, one ultralow-temperature solution reduction approach is developed to anchor atomically dispersed Pt atoms on carbon nanotubes(Pt-CNTs), which decelerates the diffusion rate of Pt Cl2-6 ion reached onto the carbon nanotubes and lowers the free energy of Pt atoms in the solution to reduce the probability of the Pt aggregation. The obtained Pt-CNTs exhibits a low overpotential of 41 mV@10 mA cm^(-2) for HER in acidic media. The calculation results revealed that the improvement of the electrocatalytic activity is contributed by the interaction between CNTs and Pt atoms, which descreases the the Pt d band cneter referred to the Fermi level and lowers the Gibbs free energy of H*adsorption. This work may provide one easy and convenient strategy for the large-scale use of Pt catalysts in practical applications. | Wenwu Zhong Wenguang Tu Zongpeng Wang Zhiping Lin Aijiao Xu Xiufang Ye Dongchu Chen Beibei Xiao | 2020 | Journal of Energy Chemistry2020，29，12： | 1 |
| 16 | SNX17 regulates Notch pathway and pancreas development through the retromer-dependent recycling of Jag1显示文摘Background:Notch is one of the most important signaling pathways involved in cell fate determination.Activation of the Notch pathway requires the binding of a membrane-bound ligand to the Notch receptor in the adjacent cell which induces proteolytic cleavages and the activation of the receptor.A unique feature of the Notch signaling is that processes such as modification,endocytosis or recycling of the ligand have been reported to play critical roles during Notch signaling,however,the underlying molecular mechanism appears context-dependent and often controversial.Results:Here we identified SNX17 as a novel regulator of the Notch pathway.SNX17 is a sorting nexin family protein implicated in vesicular trafficking and we find it is specifically required in the ligand-expressing cells for Notch signaling.Mechanistically,SNX17 regulates the protein level of Jag1a on plasma membrane by binding to Jag1a and facilitating the retromer-dependent recycling of the ligand.In zebrafish,inhibition of this SNX17-mediated Notch signaling pathway results in defects in neurogenesis as well as pancreas development.Conclusions:Our results reveal that SNX17,by acting as a cargo-specific adaptor,promotes the retromer dependent recycling of Jag1a and Notch signaling and this pathway is involved in cell fate determination during zebrafish neurogenesis and pancreas development. | Wenguang Yin Dapeng Liu Nian Liu Liangliang Xu Song Li Shuo Lin Xiaodong Shu Duanqing Pei | 2012 | Cell Regeneration2012，1，1： | 1 |
| 17 | Data-driven Product Functional Confguration:Patent Data and Hypergraph显示文摘The product functional confguration(PFC)is typically used by frms to satisfy the individual requirements of customers and is realized based on market analysis.This study aims to help frms analyze functions and realize functional confgurations using patent data.This study frst proposes a patent-data-driven PFC method based on a hypergraph network.It then constructs a weighted network model to optimize the combination of product function quantity and object from the perspective of big data,as follows:(1)The functional knowledge contained in the patent is extracted.(2)The functional hypergraph is constructed based on the co-occurrence relationship between patents and applicants.(3)The function and patent weight are calculated from the patent applicant’s perspective and patent value.(4)A weight calculation model of the PFC is developed.(5)The weighted frequent subgraph algorithm is used to obtain the optimal function combination list.This method is applied to an innovative design process of a bathroom shower.The results indicate that this method can help frms detach optimal function candidates and develop a multifunctional product. | Wenguang Lin Xiaodong Liu Renbin Xiao | 2022 | Chinese Journal of Mechanical Engineering2022，35，4： | 1 |
| 18 | A role for p21‐activated kinase 7 in the development of gastric cancer显示文摘 | Jun Gu Keqiang Li Maolan Li Xiangsong Wu Lin Zhang Qichen Ding Wenguang Wu Jiahua Yang Jiasheng Mu Hao Wen Qian Ding Jianhua Lu Yuan Hao Lei Chen Wenjie Zhang Songgang Li Yingbin Liu | 2012 | FEBS J2012，，1： | 1 |
| 19 | A role for p21‐activated kinase 7 in the development of gastric cancer显示文摘 | Jun Gu Keqiang Li Maolan Li Xiangsong Wu Lin Zhang Qichen Ding Wenguang Wu Jiahua Yang Jiasheng Mu Hao Wen Qian Ding Jianhua Lu Yuan Hao Lei Chen Wenjie Zhang Songgang Li Yingbin Liu | 2012 | FEBS J2012，，1： | 1 |
| 20 | NLK is a key regulator of proliferation and migration in gallbladder carcinoma cells显示文摘 | Zhujun Tan Maolan Li Wenguang Wu Lin Zhang Qichen Ding Xiangsong Wu Jiasheng Mu Yingbin Liu | 2012 | Molecular and Cellular Biochemistry2012，，1： | 1 |
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