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| 1 | The dynamics of the piglet gut microbiome during the weaning transition in association with health and nutrition显示文摘Background: Understanding the composition of the microbial community and its functional capacity during weaning is important for pig production as bacteria play important roles in the pig's health and growth performance. However,limited information is available regarding the composition and function of the gut microbiome of piglets in early-life.Therefore, we performed 16 S rRNA gene and whole metagenome shotgun sequencing of DNA from fecal samples from healthy piglets during weaning to measure microbiome shifts, and to identify the potential contribution of the early-life microbiota in shaping piglet health with a focus on microbial stress responses, carbohydrate and amino acid metabolism.Results: The analysis of 16 S rR NA genes and whole metagenome shotgun sequencing revealed significant compositional and functional differences between the fecal microbiome in nursing and weaned piglets. The fecal microbiome of the nursing piglets showed higher relative abundance of bacteria in the genus Bacteroides with abundant gene families related to the utilization of lactose and galactose. Prevotel a and Lactobacil us were enriched in weaned piglets with an enrichment for the gene families associated with carbohydrate and amino acid metabolism. In addition, an analysis of the functional capacity of the fecal microbiome showed higher abundances of genes associated with heat shock and oxidative stress in the metagenome of weaned piglets compared to nursing piglets.Conclusions: Overal, our data show that microbial shifts and changes in functional capacities of the piglet fecal microbiome resulted in potential reductions in the effects of stress, including dietary changes that occur during weaning.These results provide us with new insights into the piglet gut microbiome that contributes to the growth of the animal. | Robin B.Guevarra Sang Hyun Hong Jin Ho Cho Bo-Ra Kim Jiwon Shin Jun Hyung Lee Bit Na Kang Young Hwa Kim Suphot Wattanaphansak Richard E.Isaacson Minho Song Hyeun Bum Kim | 2018 | Journal of Animal Science and Biotechnology2018，9，4： | 16 |
| 2 | Dynamic visual selective attention model显示文摘 | Sang-Woo Ban Inwon Lee Minho Lee | 2007 | Neurocomputing2007，，4： | 1 |
| 3 | Policy- Based Management for Self-Managing Wireless Sensor Networks 显示文摘 | Si-Ho CHA Jong-Eon LEE Minho JO HeeYong YOUN Seokjoong KANG Kuk-Hyun CHO | 2007 | IEICE TRANSACTIONS on Communications2007，，11： | 1 |
| 4 | Fluorescence Quenching Caused by Aggregation of Water-Soluble CdSe Quantum Dots显示文摘 | Noh Minho Kim Taehoon Lee Hosub | 2010 | Colloids and Surfaces2010，359，1： | 1 |
| 5 | A Novel Small Molecule Facilitates the Reprogramming of Human Somatic Cells into a Pluripotent State and Supports the Maintenance of an Undifferentiated State of Human Pluripotent Stem Cells显示文摘 | Jungwoon Lee Yan Xia Mi‐Young Son Guanghai Jin Binna Seol Min‐Jeong Kim Myung Jin Son Misol Do Minho Lee Dongsup Kim Kyeong Lee Yee Sook Cho | 2012 | Angew Chem Int Ed2012，，50： | 1 |
| 6 | Audio Fingerprinting Based on Normalized Spectral Subband Moments显示文摘 | Jin Seo Jin Minho Lee Sunil | 2006 | IEEE Signal Process- ing2006，13，4： | 1 |
| 7 | Simultaneous registration of multiple views with markers显示文摘 | Tae-wan Kim Yeong-hwa Seo Sang-chul Lee Zhouwang Yang Minho Chang | 2008 | Computer-Aided Design2008，，4： | 1 |
| 8 | Dual specificity phosphatase 6 as a predictor of invasiveness in papillary thyroid cancer显示文摘 | Jung Uee Lee Songmei Huang Min Hee Lee Seong Eun Lee Min Jeong Ryu Soung Jung Kim Yong Kyung Kim Seul Young Kim Kyong Hye Joung Jin Man Kim Minho Shong Young Suk Jo | 2012 | European Journal of Endocrinology2012，，1： | 1 |
| 9 | Escherichia coli challenge and one type of smectite alter intestinal barrier of pigs显示文摘An experiment was conducted to determine how an E. coli challenge and dietary clays affect the intestinal barrier of pigs. Two groups of 32 pigs(initial BW: 6.9 土 1.0 kg) were distributed in a 2 x 4 factorial arrangement of a randomized complete block design(2 challenge treatments: sham or ￡ coli, and 4 dietary treatments: control, 0.3%smectite A, 0.3% smectite B and 0.3% zeolite), with 8 replicates total. Diarrhea score, growth performance, goblet cell size and number, bacterial translocation from intestinal lumen to lymph nodes, intestinal morphology, and relative amounts of sulfo and sialo mucins were measured. The ￡ coli challenge reduced performance, increased goblet cell size and number in the ileum, increased bacterial translocation from the intestinal lumen to the lymph nodes, and increased ileal crypt depth. One of the clays(smectite A) tended to increase goblet cell size in ileum,which may indicate enhanced protection. In conclusion, ￡ coli infection degrades intestinal barrier integrity but smectite A may enhance it. | Juliana Abranches Soares Almeida Yanhong Liu Minho Song Jeong Jae Lee H Rex Gaskins Carol Wolfgang Maddox Orlando Osuna James Eugene Pettigrew | 2014 | Journal of Animal Science and Biotechnology2014，5，2： | 1 |
| 10 | Devel-oping a Common Health Information Exchange Platformto Implement a Nationwide Health Information Networkin South Korea 显示文摘 | Minho Lee Eunyoung Heo Heesook Lim | 2015 | Healthc Inform Res2015，21，1： | 1 |
| 11 | Intracellular Amyloid-β Accumulation in Calcium-Binding Protein-Deficient Neurons Leads to Amyloid-β Plaque Formation in Animal Model of Alzheimer’s Disease显示文摘 | Minho Moon Hyun-Seok Hong Dong Woo Nam Sung Hoon Baik Hyundong Song Sun-Young Kook Yong Soo Kim Jeewoo Lee Inhee Mook-Jung | 2011 | Journal of Alzheimer’s Disease2011，，3： | 1 |
| 12 | A hierarchical positive and negative emotion understanding system based on integrated analysis of visual and brain signals 显示文摘 | Zhang Qing Lee Minho | 2010 | Neurocomputing2010，73，： | 1 |
| 13 | Global sliding-mode control improved design for a brushless DC motor显示文摘 | Hyeung Sik Choi Yong Heon Park Minho Lee | 2001 | IEEE Control System Magazine2001，21，3： | 1 |
| 14 | Development of large acceptance multi-purpose spectrometer in Korea for symmetry energy显示文摘The Rare Isotope Accelerator complex for ONline experiments(RAON) is a new radioactive ion beam accelerator facility under construction in Korea. The large acceptance multi-purpose spectrometer(LAMPS) is one of the experimental devices for nuclear physics at RAON. It focuses on the nuclear symmetry energy at supra-saturation densities. The LAMPS Collaboration has developed and constructed various detector elements, including a time projection chamber(TPC) and a forward neutron detector array. From the positron beam test, the drift velocity of the secondary electrons in the TPC is 5:3±0:2 cm/ls with P10 gas mixture, and the position resolution for pads with dimensions of 4×15 mm^2 is in the range of$ 0.6–0.8 mm, depending on the beam position. From the neutron beam test, the energy resolution of the prototype neutron detector module is determined to be 3.4%, and theposition resolution is estimated to be better than 5.28 cm.At present, the construction of the LAMPS neutron detector system is in progress. | Byungsik Hong Jung Keun Ahn Gyeonghwan Bak Jamin Jo Minho Kim Eun Joo Kim Young Jin Kim Young Jun Kim Minjung Kweon Hanseul Lee Hyo Sang Lee Jong-Won Lee Jung Woo Lee Kyong Sei Lee Byul Moon Dong Ho Moon Benard Mulilo Jaebeom Park Min Sang Ryu Hyunha Shim LAMPS Collaboration | 2018 | Nuclear Science and Techniques2018，29，12： | 1 |
| 15 | 大尺寸集成多重触摸功能LCD显示文摘52in红外液晶显示模块图像传感器集成了多重触摸功能,可以探测普通基板周围的触摸。方法是通过放置一些红外图像传感器来探测触摸。触摸算法中用到三角剖分、图像处理技术以及模式识别。同时通过红外图像传感器、红外光源和LCD基板计算出触摸点位置。另外,触摸数量和触摸面积用于实现多重触摸功能。多重触摸LCD也可以探测人的手势。在这里,地图寻找程序使用了触摸和手势识别。结果是多重触摸LCD显示出它的有效性,可以用来替代传统的人机界面设备(如鼠标、键盘)。 | Sang Hyuck Bae Byung Chun Yu Sangrae Lee Hyung Uk Jang Jongseong Choi Minho Sohn InHo Ahn InByeong Kang InJae Chung 赵立晴(译) | 2009 | 现代显示2009，，4： | 0 |
| 16 | Surface Characteristics of Mussel-inspired Polydopamine Coating on Titanium Substrates显示文摘Mussel adhesive proteins are non-toxic, biodegradable and have low immunogenic qualities that make them highly attractive for medical purposes compared with man-made materials. 3,4-DOPA, which is a dopamine precursor, is a critical element for achieving mussel-like adhesive properties. In present study, polydopamine was coated onto the titanium surfaces by dipping in a 2 mg/mL dopamine solution in 10 mM TrisHCl buffer at pH 8.5. EDX element analysis and Raman spectroscopic analysis of the surface were conducted to verify the formation of polydopamine. The surface characteristics of polydopamine-coated titanium plates were observed by SEM and AFM. Hydrophilicity and corrosion-resistance were also evaluated by static contact angle measurements and potentiodynamic polarization corrosion tests. The absorption intensity for pH-induced polymerization rapidly increased for the initial four hours and thereafter smoothly increased. EDX element analyses revealed that the content of carbon and oxygen increased and the content of titanium decreased after the coating process. In the Raman spectra, polydopamine resulted in two new peaks at approximately 1 370 and 1 570 cm-1resulting from the stretching and deformation of catechol. Microstructural features revealed that nanometer-sized bright granules were randomly distributed after coating, and these nanoparticles grew with increased coating time. The Ra values of polydopamine-coated titanium plates were showed to increase with coating time. Compared to the pure titanium curve, the inflection point of polydopamine-coated titanium was located at a higher corrosion potential and lower corrosion current density. Findings from our research suggested that polydopamine coatings offer a versatile approach for titanium surface modification. | 姜玲 JIN Guangchun KANG Jiyeon YU Lingmin YOON Wookang LIM MyungJin PAR K Ilsong LEE Minho JIN Dongchun | 2014 | Journal of Wuhan University of Technology(Materials Science)2014，29，1： | 0 |
| 17 | Carbon Nanotube Coating on Titanium Substrate Modified with TiO_2 Nanotubes显示文摘A combination of carbon nanotubes (CNTs) and titanium (Ti) modified with TiO2 nanotubes (TiO2 NTs) was fulfilled with the aim of improving bioactivity of Ti implant.First,well-ordered TiO2 NTs were prepared by the electrochemical anodization of Ti in an ethylene glycol electrolyte containing 1 wt% NH4F and 10 wt% H2O at 20 V for 50 min,followed by annealing.Then,the carboxylated CNTs were coated onto the TiO2 NTs using electrophoretic deposition (EPD) technique.The growth of hydroxyapatite (HA) on the samples was investigated by soaking them in simulated body fluid (SBF).The result showed the CNTs-coated Ti with the modification of TiO2 NTs (CNTs-TiO2 NTs) was more efficient to induce HA formation than the CNTs-coated smooth Ti (CNTs-Ti).The vitro cell response was evaluated using osteoblast cells (MC3T3-E1).The good cell proliferation and strong cell adhesion could be obtained on the CNTs-TiO2 NTs.These results indicated that CNT coating on the Ti modified with TiO2 NTs could be potentially useful for the periodontal ligament combination on dental implants. | 白玉 PARK Ilsong BAE Taesung KIM Kyounga WATARI Fumio UO Motohiro LEE Minho | 2011 | Journal of Wuhan University of Technology(Materials Science)2011，26，5： | 0 |
| 18 | 增强核心肌群训练的家用划船机设计显示文摘现在,家庭锻炼变得比以往更加普遍,“健身狂”探索更实用的选择。虽然,哑铃和举重杆较容易获得,但为特定的身体调理方案购买硬核机器也是必要的。机器外观如何?是否适合现代室内空间?都是值得深思的问题。划船是一项可以锻炼肩部、背部、二头肌和三头肌,以及核心肌群的重要运动。因此利用划船机锻炼比其它任何单一肌肉锻炼机器更具优势。由于室内空间非常有限,因而小巧、轻便的划船机就是较好的健身器材选择。Minho Lee设计的Beam划船机就是其中之一。 | Minho Lee | 2022 | 工业设计2022，，4： | 0 |
| 19 | Cell-type continuous electromagnetic radiation system generating millimeter waves for active denial system applications显示文摘The cell-type continuous electromagnetic radiation system is a demonstration device capable of generating high-power millimeter electromagnetic waves of a specific wavelength and observing their effects on living organisms.It irradiates a biological sample placed in a 30×30×50 cm^(3)cell with electromagnetic waves in the 3.15-mm-wavelength region(with an output of≥1 W)and analyzes the temperature change of the sample.A vacuum electronic device-based coupled-cavity backward-wave oscillator converts the electron energy of the electron beam into radiofrequency(RF)energy and radiates it to the target through an antenna,increasing the temperature through the absorption of RF energy in the skin.The system causes pain and ultimately reduces combat power.A cell-type continuous electromagnetic radiation system consisting of four parts—an electromagnetic-wave generator,a highvoltage power supply,a test cell,and a system controller—generates an RF signal of≥1 W in a continuous waveform at a 95-GHz center frequency,as well as a chemical solution with a dielectric constant similar to that of the skin of a living organism.An increase of 5°C lasting approximately 10 s was confirmed through an experiment. | Sun-Hong Min Ohjoon Kwon Matlabjon Sattorov Seontae Kim In-Keun Baek Seunghyuk Park Ranjan Kumar Barik Anirban Bera Dongpyo Hong Seonmyeong Kim Bong Hwan Hong Chawon Park Sukhwal Ma Minho Kim Kyo Chul Lee Yong Jin Lee Han Byul Kwon Young Joon Yoo Sang Yoon Park Gun-Sik Park | 2022 | Defence Technology(防务技术)2022，18，10： | 0 |
| 20 | Gram-negative bacteria and their lipopolysaccharides in Alzheimer’s disease:pathologic roles and therapeutic implications显示文摘Alzheimer's disease(AD)is the most serious age-related neurodegenerative disease and causes destructive and irreversible cognitive decline.Failures in the development of therapeutics targeting amyloid-β(Aβ)and tau;principal proteins inducing pathology in AD,suggest a paradigm shift towards the development of new therapeutic targets.The gram-negative bacteria and lipopolysaccharides(LPS)are attractive new targets for AD treatment.Surprisingly,an altered distribution of gram-negative bacteria and their LPS has been reported in AD patients.Moreover,gram-negative bacteria and their LPS have been shown to affect a variety of AD-related pathologies,such as Aβ homeostasis,tau pathology,neuroinflammation,and neurodegeneration.Moreover,therapeutic approaches targeting gram-negative bacteria or gram-negative bacterial molecules have significantly alleviated AD-related pathology and cognitive dysfunction.Despite multiple evidence showing that the gram-negative bacteria and their LPS play a crucial role in AD pathogenesis,the pathogenic mechanisms of gram-negative bacteria and their LPS have not been clarified.Here,we summarize the roles and pathomechanisms of gram-negative bacteria and LPS in AD.Furthermore,we discuss the possibility of using gram-negative bacteria and gram-negative bacterial molecules as novel therapeutic targets and new pathological characteristics for AD. | Hyeon soo Kim Sujin Kim Soo Jung Shin Yong Ho Park Yunkwon Nam Chae won Kim Kang won Lee Sung-Min Kim In Duk Jung Hyun Duk Yang Yeong-Min Park Minho Moon | 2021 | Translational Neurodegeneration2021，10，4： | 0 |
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