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| 1 | 多频海底声学原位测试系统研制和试用显示文摘海底沉积物的声学特性(最重要的是声速和声衰减)以及它们与物理(包括土力学)特性之间的关系是沉积物声学中两个重要的研究项目.介绍了新研制的实时监控多频海底声学原位测试系统.该系统可测量浅表层沉积物的声速.探测频率为8,10,12,15kHz,可根据实际情况选择发射波形、接收增益和采样长度,采样率为0.5~2.0MHz,工作水深为300m.系统具有倾斜传感器、8通道扩充等功能.用该系统在杭州湾测得了四种频率的沉积物原位声速. | 陶春辉 金肖兵 金翔龙 周建平 张金辉 顾春华 何拥华 WIL KENS R H FU Shung-sheng | 2006 | 海洋学报2006,28,2: | 23 |
| 2 | Effects of adacolumn selective leukocytapheresis on plasma cytokines during active disease in patients with active ulcerative colitis显示文摘瞄准:调查在临床的活动索引的 ulcerative (UC )( 蔡) 和 IL-1ra, IL-10, IL-6 和 IL-18 的传播层次之间的关系。方法:IL-1ra, IL-10, IL-6 和 IL-18 的血层次与活跃 UC 在 31 个病人被测量,吝啬的蔡是 11.1,从 5-25 ;并且是的 12 个健康个人控制。病人们与 Adacolumn 被给粒细胞和单核白血球 adsorptive 词首字母的脱落(GMA ) 。忍受 FcgammaR 并且补充受体的白细胞被吸附到列 leucocytapheresis 搬运人。每个病人能在 8 wk 上收到多达 11 个 GMA 会议。结果:我们发现了在蔡和 IL-10 之间的强壮的关联(r = 0.827, P <
0.001 ) , IL-6 (r = 0.785, P <
0.001 ) 并且 IL-18 (r = 0.791, P <
0.001 ) 。IL-1ra 没与蔡一起被相关。后面的 GMA 治疗, 31 个病人中的 24 个完成了宽恕,所有 4 cytokines 的层次掉在健康控制里到层次。进一步, IL-1ra 和 IL-10 的血层次在从遵守了搬运人的白细胞建议版本的 60 min 在列流出和流入增加了。 | Hiroyuki Hanai Takayuki Iida Masami Yamada Yoshihiko Sato Ken Takeuchi Tatsuo Tanaka Kenji Kondo Masataka Kikuyama Yasuhiko Maruyama Yasushi Iwaoka Akiko Nakamura Kazuhisa Hirayama Abby R Saniabadi Fumitoshi Watanabe | 2006 | World Journal of Gastroenterology2006,12,21: | 8 |
| 3 | Dual destructive and protective roles of adaptive immunity in neurodegenerative disorders显示文摘Inappropriate T cell responses in the central nervous system(CNS)affect the pathogenesis of a broad range of neuroinflammatory and neurodegenerative disorders that include,but are not limited to,multiple sclerosis,amyotrophic lateral sclerosis,Alzheimer’s disease and Parkinson’s disease.On the one hand immune responses can exacerbate neurotoxic responses;while on the other hand,they can lead to neuroprotective outcomes.The temporal and spatial mechanisms by which these immune responses occur and are regulated in the setting of active disease have gained significant recent attention.Spatially,immune responses that affect neurodegeneration may occur within or outside the CNS.Migration of antigen-specific CD4+T cells from the periphery to the CNS and consequent immune cell interactions with resident glial cells affect neuroinflammation and neuronal survival.The destructive or protective mechanisms of these interactions are linked to the relative numerical and functional dominance of effector or regulatory T cells.Temporally,immune responses at disease onset or during progression may exhibit a differential balance of immune responses in the periphery and within the CNS.Immune responses with predominate T cell subtypes may differentially manifest migratory,regulatory and effector functions when triggered by endogenous misfolded and aggregated proteins and cell-specific stimuli.The final result is altered glial and neuronal behaviors that influence the disease course.Thus,discovery of neurodestructive and neuroprotective immune mechanisms will permit potential new therapeutic pathways that affect neuronal survival and slow disease progression. | Kristi M Anderson Katherine E Olson Katherine A Estes Ken Flanagan Howard E Gendelman R Lee Mosley | 2014 | Translational Neurodegeneration2014,3,1: | 8 |
| 4 | Characteristics of Missed or Interval Colorectal Cancer and Patient Survival: A Population-Based Study显示文摘 | N. Jewel Samadder Karen Curtin Thérèse M.F. Tuohy Lisa Pappas Ken Boucher Dawn Provenzale Kerry G. Rowe Geraldine P. Mineau Ken Smith Richard Pimentel Anne C. Kirchhoff Randall W. Burt | 2014 | Gastroenterology2014,,4: | 2 |
| 5 | Sex-specific differences in white matter microvascular integrity after ischaemic stroke显示文摘background and purpose Functional outcomes after ischaemic stroke are worse in women,despite adjusting for differences in comorbidities and treatment approaches.White matter microvascular integrity represents one risk factor for poor long-term functional outcomes after ischaemic stroke.The aim of the study is to characterise sex-specific differences in microvascular integrity in individuals with acute ischaemic stroke.Methods A retrospective analysis of subjects with acute ischaemic stroke and brain MRI with diffusion-weighted(DWI)and dynamic-susceptibility contrast-enhanced(DSC)perfusion-weighted imaging obtained within 9 hours of last known well was performed.In the hemisphere contralateral to the acute infarct,normal-appearing white matter(NAWM)microvascular integrity was measured using the K_(2) coefficient and apparent diffusion coefficient(ADC)values.Regression analyses for predictors of K_(2) coefficient,DWI volume and good outcome(90-day modified Rankin scale(mRS)score<2)were performed.results 105 men and 79 women met inclusion criteria for analysis.Despite no difference in age,women had increased NAWM K_(2) coefficient(1027.4 vs 692.7×10^(-6)/s;p=0.006).In women,atrial fibrillation(β=583.6;p=0.04)and increasing NAWM ADC(β=4.4;p=0.02)were associated with increased NAWM K_(2) coefficient.In multivariable regression analysis,the K_(2) coefficient was an independent predictor of DWI volume in women(β=0.007;p=0.01)but not men.Conclusions In women with acute ischaemic stroke,increased NAWM K_(2) coefficient is associated with increased infarct volume and chronic white matter structural integrity.Prospective studies investigating sex-specific differences in white matter microvascular integrity are needed. | Mark R Etherton Ona Wu Pedro Cougo Svetlana Lorenzano Hua Li Lisa Cloonan Mark J R J Bouts Arne Lauer Ken Arai Eng H Lo Steve K Feske Karen L Furie Natalia S Rost | 2019 | Stroke & Vascular Neurology2019,4,4: | 2 |
| 6 | Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study显示文摘 | Julia Granerod Helen E Ambrose Nicholas WS Davies Jonathan P Clewley Amanda L Walsh Dilys Morgan Richard Cunningham Mark Zuckerman Ken J Mutton Tom Solomon Katherine N Ward Michael PT Lunn Sarosh R Irani Angela Vincent David WG Brown Natasha S Crowcroft | 2010 | The Lancet Infectious Diseases2010,,12: | 2 |
| 7 | Convective heat transfer to water containing bubbles:enhancement not dependent on thermocapillarity 显示文摘 | KENNING D B R KAO Y S | 1972 | Int J Heat Mass Transfer1972,15,: | 2 |
| 8 | Different roles for human lung den- dritic cell subsets in pulmonary immune defense mechanisms 显示文摘 | Ingel K D Ken R B Tania M | 2006 | Am J Respir Cell Mol Biol2006,35,4: | 1 |
| 9 | Glutamine protects against doxorubicin-induced cardiotoxicity显示文摘 | Cao Y Kenned R Klimberg VS | 1999 | J Surg Res1999,85,2: | 1 |
| 10 | Variability of inorganic and organic phosphorus turnover rates in the coastal ocean显示文摘 | CLAUDIA R Benitez - Nelson KEN 0 Buesseler | 1999 | Nature1999,398,: | 1 |
| 11 | Flavonoid gene expression and UV photoprotection in transgenic and mutant Petunia leaves 显示文摘 | Ken G Rayan Ewald E Swinny Kenneth R Markham | 2002 | Phytochemistry2002,59,: | 1 |
| 12 | Quantitative Contrast-EnhancedUltrasound Parameters inCrohn Disease: Their Role inDisease Activity DeterminationWith U1trasound显示文摘 | Mede11in-Kowalewski A Wi 1 kens R Wilson A | 2016 | AJR Am JRoentgenol2016,206,1: | 1 |
| 13 | Characterizing high-speed oscilloscopes显示文摘 | Ken R Steve D John K | 1990 | IEEE Spectrum1990,,: | 1 |
| 14 | Multivariate morphometric analysis of the Apis cerana of China 显示文摘 | TAN Ken HEPBUM H R RADLOFF S E | 2008 | Apidologie2008,39,3: | 1 |
| 15 | Individual Characterization of Broadband Sampling Oscilloscopes with a 'Nose-to-Nose' Calibration Procedure显示文摘 | Jan V Ken R | 1994 | IEEE Transaction on Instrumentation and Measurement1994,43,2: | 1 |
| 16 | The mid-Cretaceous super plume, carbon dioxide, and global warming 显示文摘 | Ken Caldeira Michael R Rampino | 1991 | Geophysical Research Letters1991,18,6: | 1 |
| 17 | Isokinetic testing of shoulder strength: normal values显示文摘 | Frank MIJ Jason HC Ken R | 1985 | Arch Phys Med Rehabil1985,66,: | 1 |
| 18 | Freeman,Cystoventricular Shunting of Intracranial Arachnoid Cysts显示文摘 | Lori A Bride M Ken R | 2003 | Pediatr neurosurg2003,39,6: | 1 |
| 19 | Two-Phase Pressure Drop of Water During Flow Boiling in a Vertical Narrow Chan nel显示文摘 | Wen D S Kenning D B R | 2004 | Experimental Thermal and Fluid Science2004,28,: | 1 |
| 20 | 显示文摘 | Scott R S Ken B A Kathleen A C | 2002 | Applied Catalysis2002,231,: | 1 |