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| 1 | Portal vein thrombosis in liver cirrhosis显示文摘Portal vein thrombosis(PVT) is considered to be a frequent complication of liver cirrhosis. However, unlike PVT in patients without cirrhosis, very few data are available on the natural history and management of PVT in cirrhosis, despite its association with potentially life-threatening conditions, such as gastroesophageal bleeding and acute intestinal ischemia. Moreover, no consensus regarding PVT in cirrhosis exists. Suggested causes of PVT in cirrhosis include reduced portal blood flow velocity, multiple congenital or acquired thrombophilic factors, inherited or acquired conditions, and derangement of liver architecture. However, the understanding of PVT in cirrhosis is incomplete. In addition, information on the management of PVT in cirrhosis is inadequate. The aims of this review are to:(1) assemble data on the physiopathological mechanism, clinical findings, diagnosis and management of PVT in cirrhosis;(2) describe the principal factors most frequently involved in PVT development; and(3) summarize the recent knowledge concerning diagnostic and therapeutic procedures. | Nao Kinjo Hirofumi Kawanaka Tomohiko Akahoshi Yoshi-hiro Matsumoto Masahiro Kamori Yoshihiro Nagao Naotaka Hashimoto Hideo Uehara Morimasa Tomikawa Ken Shirabe Yoshihiko Maehara | 2014 | World Journal of Hepatology2014,6,2: | 38 |
| 2 | Hepatitis B:Who should be treated?-managing patients with chronic hepatitis B during the immune-tolerant and immunoactive phases显示文摘New hepatitis B virus(HBV)infections are decreasing owing to improved antiviral therapy and increased HBV vaccination worldwide;however,the number of HBV infections remains a major cause of liver carcinogenesis.HBV triggers cytotoxic immunity to eliminate HBV-infected cells.Therefore,the HBV pathophysiology changes in persistently infected individuals depending on host immune responses and HBV DNA proliferation state.To prevent liver cirrhosis and carcinogenesis caused by HBV,it is important to treat HBV infection at an early stage.Active treatment is recommended for the immunoactive hepatitis B surface-antigen-positive and-negative phase,but not during the immune-inactive phase or immune-tolerant phase;instead,follow-up is recommended.However,these patients should be monitored through regular blood tests to accurately diagnose the immune-inactive or-tolerant phases.The treatment regimen should be determined based on the age,sex,family history of liver cancer,and liver fibrosis status of patients.Early treatment is often recommended due to various problems during the immune-tolerant phase.This review compares the four major international practice guidelines,including those from the Japanese Society of Hepatology,and discusses strategies for chronic hepatitis B treatment during the immune-tolerant,immune-inactive,and resolved phases.Finally,recommended hepatitis B antiviral therapy and follow-up protocols are discussed. | Miwa Kawanaka Ken Nishino Hirofumi Kawamoto Ken Haruma | 2021 | World Journal of Gastroenterology2021,27,43: | 5 |
| 3 | Present status of fast ignition realization experiment and inertial fusion energy development显示文摘 | H. Azechi K. Mima S. Shiraga S. Fujioka H. Nagatomo T. Johzaki T. Jitsuno M. Key R. Kodama M. Koga K. Kondo J. Kawanaka N. Miyanaga M. Murakami K. Nagai M. Nakai H. Nakamura T. Nakamura T. Nakazato Y. Nakao K. Nishihara H. Nishimura T. Norimatsu P. Norrey | 2013 | Nuclear Fusion2013,,10: | 3 |
| 4 | Impact of Antithrombin III Concentrates on Portal Vein Thrombosis After Splenectomy in Patients With Liver Cirrhosis and Hypersplenism显示文摘 | Hirofumi Kawanaka Tomohiko Akahoshi Nao Kinjo Kozou Konishi Daisuke Yoshida Go Anegawa Shohei Yamaguchi Hideo Uehara Naotaka Hashimoto Norifumi Tsutsumi Morimasa Tomikawa Yoshihiko Maehara | 2010 | Annals of Surgery2010,,1: | 2 |
| 5 | Treatment of nonalcoholic steatohepatitis with vitamins E and C: a pilot study显示文摘 | Miwa Kawanaka Mitsuhiko Suehiro Gotaro Yamada Jun Nakamura Keisuke Hino Ken Nishino Junji Yodoi Hajime Nakamura Hirofumi Kawamoto Takahito Oka Noriyo Urata Daisuke Goto | 2013 | 2013 (defa)2013,,: | 2 |
| 6 | Characteristics of Patients With Nonalcoholic Steatohepatitis Who Develop Hepatocellular Carcinoma显示文摘 | Kohichiroh Yasui Etsuko Hashimoto Yasuji Komorizono Kazuhiko Koike Shigeki Arii Yasuharu Imai Toshihide Shima Yoshihiro Kanbara Toshiji Saibara Takahiro Mori Sumio Kawata Hirofumi Uto Shiro Takami Yoshio Sumida Toshinari Takamura Miwa Kawanaka Takeshi Oka | 2011 | Clinical Gastroenterology and Hepatology2011,,5: | 2 |
| 7 | Gene therapy for gastric ulcers with single local injection of naked DNA encoding VEGF and angiopoietin-1 显示文摘 | Jones MK Kawanaka H Baatar D | 2001 | Gastroenterology2001,121,5: | 1 |
| 8 | Impact of antithrombin Ⅲ concentrates on portal vein thrombosis after splenectomy in patients with liver cirrhosis and hypersplenism显示文摘 | Kawanaka H Akahoshi T Kinjo N | 2010 | Ann Surg2010,251,1: | 1 |
| 9 | Effects of high-intensity swimming training on GLUT-4 and glucose transport activity in rat skeletal muscle显示文摘 | Terada S Yakozeki T Kawanaka K | 2001 | J Appl Physiol2001,90,6: | 1 |
| 10 | Effect of Laparo-scopic Splenectomy on Portal Hypertensive Gastropathy inCirrhotic Patients with Portal Hypertension显示文摘 | Anegawa G Kawanaka H Uehara H | 2009 | J Gastroen-terol Hepatol2009,24,9: | 1 |
| 11 | Risk factors for radiation pneumonitis caused by whole breast irradiation following breast-conserving surgery显示文摘 | Kubo A Osaki K Kawanaka T | 2009 | Med Invest2009,56,34: | 1 |
| 12 | Radar imaging of underground pipes by automated estimation of velocity distribution versus depth显示文摘 | Hideki Hayakawa Akira Kawanaka | 1998 | Journal of Applied Geophysics1998,40,: | 1 |
| 13 | yon Hippel Lindau tumor suppressor and HIF-1 alpha: New targets of NSAIDs inhibition of hypnxia-induced angiogenesis 显示文摘 | Jones MK Szabo IL Kawanaka H Husain SS Tarnawski AS | 2002 | FASEB J2002,16,2: | 1 |
| 14 | Abnormality of the hepatic vein waveforms in cirrhotic patients with portal hypertension and its prognostic implications 显示文摘 | Kawanaka H Kinjo N Anegawa G | 2008 | J Gastroenterol Hepatol2008,23,7: | 1 |
| 15 | Branched-chain amino acid-containing dipeptide from whey protein hydrolysates,stimulate glucose uptake rate in L6 myotubes and isolated skeletal muscles显示文摘 | Morifuji M Koga J Kawanaka K | | 0,,1: | 1 |
| 16 | 显示文摘 | Kakeshita T Shimizu K Kawanaka R | 1982 | J Matls Sci1982,17,: | 1 |
| 17 | Risk factors for portalvenous thrombosis after splenectomy in patients with cirriiosis andportal hypertension显示文摘 | Kinjo N Kawanaka H Akahoshi T | 2010 | Br J Surg2010,97,6: | 1 |
| 18 | Post-exercise carbohydrate plus whey protein hydrolysates supplementation increase skeletal muscle glycogen level in rats显示文摘 | Morifuji M Kanda A Kawanaka K | | 0,,4: | 1 |
| 19 | Risk factors for radiation pneumonitis caused by whole breast irradiation following breastconserving surgery显示文摘 | Kubo A Osaki K Kawanaka T | | 0,,3: | 1 |
| 20 | Technical stan- danlization of laparoscopic splenectomy harmonized with hand-assisted laparoscopic surgery for patients with liver cirrhosis and hypersplenism显示文摘 | Kawanaka H Akahoshi T Kinjo N | 2009 | J Hepatobiliary Pancreat Surg2009,16,6: | 1 |