|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The efficacy and safety of endovascular recanalization of occluded large cerebral arteries during the subacute phase of cerebral infarction:a case series report显示文摘background Intravenous tissue plasminogen activator with or without mechanical thrombectomy during the acute phase are approved therapies for ischaemic stroke.Due to the short treatment time window(<6 hours)and often treatment failure,these patients would still have an intracranial arterial occlusion(IAO).It is unclear whether these patients can benefit from subsequent interventional recanalizationof their occluded artery in the subacute phase.In this retrospective study,we have examined the efficacy and safety in patients who have received either percutaneous transluminal angioplasty(PTA)or percutaneous transluminal angioplasty and stenting(PTAS)for IAO in the subacute phase of their stroke.Methods Patients with subacute symptomatic ischaemic stroke caused by IAO were assessed to identify the responsible artery and low perfusion areas by CT angiography,MR angiography or digital subtraction angiography.In eligible patients,a PTA or PTAS was performed to reopen the occluded artery.Regular antithrombotic therapy,use of statins,control of risk factors and rehabilitation therapy were prescribed after the procedure.All patients had regular follow-up up to 12 months.results PTA or PTAS was performed in 16 patients with cerebral infarction caused by IAO in the subacute phase.After the procedure,12 cases were recanalized,two were partially recanalized and two failed to open.One patient with left C6 segment occlusion of the carotid artery had a central retinal artery embolism after PTAS.The perioperative adverse events were 6.25%.At 3 months,the distribution of modified Rankin scale scores was 0(seven cases),1(three cases),2(five cases)and 3(one case).conclusion Selective PTA or PTAS could be performed in ischaemic stroke patients with a small infarct size and large area of hypoperfusion from an occluded large cerebral artery after the acute phase.It may improve neurological dysfunction and reduce the incidence of disability. | Kangning Chen Xianhua Hou Zhenhua Zhou Guangjian Li Qu Liu Li Gui Jun Hu Shugui Shi | 2017 | Stroke & Vascular Neurology2017，2，3： | 41 |
| 2 | Stenting for symptomatic intracranial arterial stenosis in China:1-year outcome of a multicentre registry study显示文摘background and purpose A multicentre prospective registry study of individually tailored stenting for a patient with symptomatic intracranial atherosclerotic stenosis(ICAS)combined with poor collaterals in China showed that the short-term safety and efficacy of stenting was acceptable.However,it remained uncertain whether the low event rate could be of a long term.We reported the 1-year outcome of this registry study to evaluate the long-term efficacy of individually tailored stenting for patients with severe symptomatic ICAS combined with poor collaterals.Methods Patients with symptomatic ICAS caused by 70%-99% stenosis located at the intracranial internal carotid,middle cerebral,intracranial vertebral or basilar arteries combined with poor collaterals were enrolled.Balloon-mounted stent or balloon plus self-expanding stent were selected based on the ease of vascular access and lesion morphology determined by the operators.The primary outcome was the rate of 30-day stroke,transient ischaemic attack and death,and 12-month ischaemic stroke within the same vascular territory,haemorrhagic stroke and vascular death after stenting.results From September 2013 to January 2015,300 patients(ages 58.3±9.78 years)were recruited.Among them,159 patients were treated with balloon-mounted stent and 141 with balloon plus self-expanding stent.During the 1-year follow-up,25 patients had a primary end point event.The probability of primary outcome at 1 year was 8.1%(95% CI 5.3% to 11.7%).In 76 patients with digital subtraction angiography follow-up,27.6%(21/76)had re-stenosis≥50% and 18.4%(14/76)had re-stenosis≥70%.No baseline characteristic was associated with the primary outcome.Conclusion The event rate remains low over 1 year of individually tailored stenting for patients with severe symptomatic ICAS combined with poor collaterals.Further randomised trial of comparing individually tailored stenting with best medical therapy is needed. | Ning Ma Yong Zhang Jie Shuai Changchun Jiang Qiyi Zhu Kangning Chen Li Liu Baomin Li Xiangqun Shi Lianbo Gao Yajie Liu Feng Wang Yongli Li Tieyan Liu Hongbo Zheng Dapeng Mo Feng Gao Yilong Wang Yongjun Wang Lei Feng Zhongrong Miao | 2018 | Stroke & Vascular Neurology2018，3，3： | 29 |
| 3 | Endovascular therapy for Acute ischemic Stroke Trial (EAST): study protocol for a prospective, multicentre control trial in China显示文摘Background and purpose:5 recent trials have shown the benefit of endovascular treatment for acute ischaemic stroke(AIS)due to large vessel occlusion of the anterior circulation.This study aims to evaluate the safety and efficacy of Solitaire thrombectomy in patients with moderate-to-severe stroke in the Chinese population,which has a high prevalence of intracranial atherosclerosis.Methods and analysis:This multicentre prospective control study will involve 17 stroke centres in China,and plans to recruit 150 patients in the intervention group,and 150 patients in the medical group,in which patients meet enrolment criteria but refuse intervention.Patients with AIS due to large vessel occlusion indicated for treatment with Solitaire stent retriever within 12 hours of symptom onset,and who meet the inclusion and exclusion criteria,will be enrolled in this study.The primary efficacy endpoint is functional independence as defined by a modified Rankin Scale(mRS)score≤2 at 90 days or by functional improvement as defined by mRS,using shift analysis.The procedural efficacy endpoint is arterial recanalisation of the occluded target vessel measured by a modified Thrombolysis in Cerebral Infarction(mTICI)score equal or superior to 2b right following the use of the study device.The primary safety endpoint is symptomatic intracranial haemorrhage(sICH)within 24±3 hours postprocedure.Ethics and dissemination:The protocol was approved by the Ethics Committee at the coordinating centre and by the local Institutional Review Board of each participating centre.Trial registration number:NCT02350283. | Zhongrong Miao Xiaochuan Huo Feng Gao Xiaoling Liao Chunjuan Wang Ya Peng Yibin Cao Shengli Chen Meng Zhang Changchun Jiang Xiaoxiang Peng Cunfeng Song Liping Wei Qiyi Zhu Zaiyu Guo Li Liu Hang Lin Hua Yang Wei Wu Hui Liang Anding Xu Kangning Chen Xingquan Zhao Yuesong Pan Hao Li Liping Liu Yilong Wang Yongjun Wang EAST investigators | 2016 | Stroke & Vascular Neurology2016，1，2： | 8 |
| 4 | Optimal operation strategy for distributed battery aggregator providing energy and ancillary services显示文摘The high penetration of distributed renewable energy raises a higher concern for the safe and economic operation of the smart grid. Distributed batteries equipped in demand-side can not only contribute to the reliability and security of the grid, but also make profits by participating in the electricity market, especially when distributed batteries are combined and operated by an aggregator.Considering the well-operated mechanism of performance based regulation(PBR) in the U.S. electricity market, it becomes increasingly lucrative for batteries to participate not only in energy markets for energy arbitrage, but also in ancillary service markets to provide regulation and peakload shaving services. In this study, distributed batteries are operated and coordinated by the aggregator, which simultaneously submits offers to the energy and the ancillary service markets as an individual entity. An optimaldecision model is formulated for the aggregator to determine the operation and bidding strategy for the distributed batteries by considering the characteristics of batteries,including the terms of capacity, efficiency and degradation cost. Finally, a numerical case is conducted to evaluate the benefits of the decision model. | Kangning LIU Qixin CHEN Chongqing KANG Wei SU Guobin ZHONG | 2018 | Journal of Modern Power Systems and Clean Energy2018，6，4： | 7 |
| 5 | The spatial distribution and factors affecting karst cave development in Guizhou Province显示文摘这研究越过贵州省检验 4960 个洞的分发特征,当探查在洞之间的关系时空间模式和地理元素。这研究基于 hydrogeological 和贵州的地志的地图。ArcGIS 软件被用来处理洞的邻近的索引,空间分析,和联合分析高度和经度,以及岩石性质,岩性学,排水和几乎 5000 个洞的构造分割。基于贵州洞的点模式分析,邻近的索引是 0.53,并且 Tyson 多角形验证的变化的系数到达了 72.469% 。这个数字反映洞的聚类的分发模式。越过全部省,洞被划分成四个集中的区域和一个微弱地影响的区域。四个集中的区域是 Zunyi-Tongren, Bijie, Qianxinan-Liupanshui,和 Guiyang- Anshun-Qinan。一个微弱地影响的地区是 Qiandongnan。大多数在他们之中专注是 Guiyang-Anshun-Qiannan 区域,它盖住 24.67% 全部的省区域,并且说明 36.63% 全部的省洞。在贵州的洞分发在西方的部分作为稠密被描绘并且在东方部分稀少。在这个学习背景下面,形成,包括的岩性学,结构,气候,水文学,和高度的自然元素,和他们洞开发的分发,数字,和空间模式上的效果被分析。 | ZHOU Zhongfa ZHANG Shaoyun XIONG Kangning LI Bo TIAN Zhonghui CHEN Quan YAN Lihui XlAO Shizhen | 2017 | Journal of Geographical Sciences2017，27，8： | 4 |
| 6 | Multi-sensor image registration by combining local self-similarity matching and mutual information显示文摘Automatic multi-sensor image registration is a challenging task in remote sensing.Conventional image registration algorithms may not be applicable when common underlying visual features are not distinct.In this paper,we propose a novel image registration approach that integrates local self-similarity (LSS)and mutual information (MI)for multi-sensor images with rigid/non- rigid radiometric and geometric distortions.LSS is a well- performing descriptor that captures common,local internal layout features for multi-sensor images,whereas MI focuses on global intensity relationships.First,potential control points are identified by using the Harris algorithm and screened based on the self-similarity of their local surrounding internal layouts.Second,a Bayesian prob- abilistic model for matching the ensemble of the LSS features is introduced.Third,a particle swarm optimization (PSO)algorithm is adopted to optimize the point and region correspondences for maximum self-similarity and MI and,ultimately,a robust mapping function.The proposed approach is compared with several conventional image registration algorithms that are based on the sum of squared differences (SSD),scale-invariant feature trans- forms (SIFT),and speeded-up robust features (SURF) through the experimental registration of pairs of Landsat TM,SPOT,and RADARSAT SAR images.The results demonstrate that the proposed approach is efficient and accurate. | Xiaoping LIU Shuli CHEN Li ZHUO Jun LI Kangning HUANG | 2018 | Frontiers of Earth Science2018，12，4： | 4 |
| 7 | Layered MoS2@graphene functionalized with nitrogen-doped graphene quantum dots as an enhanced electrochemical hydrogen evolution catalyst显示文摘A novel three-dimensional (3D) layered MoS2@graphene functionalized with nitrogen-doped graphene quantum dots (MoS2@N-GQDs-GR) composites as an enhanced electrochemical hydrogen evolution catalyst. The few layered MoS2 nanoflowers supported on N-GQDs-GR surface were elaborately fabricated by one-pot hydrothermal method, which MoS2 and N-GQDs-GR exist in a bonding manner of Mo-N. In addition, due to the layered MoS2 sheet edge exposes more hydrogen evolution active sites and N-GQDs-GR have high conductivity, the composites exhibit prominent electrocatalytic activity with a low overpotential 99 mV, a small Tafel slope 49.3 mV/dec. Therefore, that the current work will develop HER catalysts may replace Pt. | Tong Guo Lina Wang Sen Sun Yan Wang Xiaoling Chen Kangning Zhang Dongxia Zhang Zhonghua Xue Xibin Zhou | 2019 | Chinese Chemical Letters2019，30，6： | 3 |
| 8 | Blue LED-pumped intense short-wave infrared luminescence based on Cr^(3+)-Yb^(3+)-co-doped phosphors显示文摘The growing demand for spectroscopy applications in the areas of agriculture,retail and healthcare has led to extensive research on infrared light sources.The ability of phosphors to absorb blue light from commercial LED and convert the excitation energy into long-wavelength infrared luminescence is crucial for the design of cost-effective and high-performance phosphor-converted infrared LEDs.However,the lack of ideal blue-pumped short-wave infrared(SWIR)phosphors with an emission peak longer than 900 nm greatly limits the development of SWIR LEDs using light converter technology.Here we have developed a series of SWIR-emitting materials with high luminescence efficiency and excellent thermal stability by co-doping Cr^(3+)-Yb^(3+) ion pairs into Lu_(0.2)Sc_(0.8)BO_(3) host materials.Benefitting from strong light absorption of Cr^(3+) in the blue waveband and very efficient Cr^(3+)→Yb^(3+) energy transfer,the as-synthesized Lu_(0.2)Sc_(0.8)BO_(3):Cr^(3+),Yb^(3+) phosphor emits intense SWIR light in the 900-1200 nm from Yb^(3+) under excitation with blue light at~460 nm.The optimized phosphor presents an internal quantum yield of 73.6%and the SWIR luminescence intensity at 100℃can still keep 88.4%of the starting value at 25℃.SWIR LED prototype device based on Lu0.2Sc0.8BO3∶Cr^(3+)Yb^(3+) phosphor exhibits exceptional luminescence performance,delivering SWIR radiant power of 18.4 mW with 9.3%of blue-to-SWIR power conversion efficiency and 5.0%of electricity-to-SWIR light energy conversion efficiency at 120 mA driving current.Moreover,under the illumination of high-power SWIR LED,covert information identification and night vision lighting have been realized,demonstrating a very bright prospect for practical applications. | Yan Zhang Shihai Miao Yanjie Liang Chao Liang Dongxun Chen Xihui Shan Kangning Sun Xiao-Jun Wang | 2022 | Light(Science & Applications)2022，11，6： | 3 |
| 9 | Zuogui pills for myelinolysis in a rat model of experimental autoimmune encephalomyelitis显示文摘Zuogui pills have been shown to attenuate the inflammatory reaction in a rat model of experimental autoimmune encephalomyelitis(EAE).The present study attempted to investigate the pathology underlying the influence of Zuogui pills on myelinolysis in EAE rats.Hematoxylin-eosin and Luxol fast blue staining showed that the myelinolysis foci in the cerebrum,cerebellum,brain stem,and the spinal cord of EAE rats were significantly decreased,along with serum myelin basic protein content following treatment with Zuogui pills. | Yongping Fan Kelong Chen Kangning Li Jianping Zhou Yan Shao Hongyan Liu WenjingYang | 2011 | Neural Regeneration Research2011，6，9： | 2 |
| 10 | Flexible bioelectronics for physiological signals sensing and disease treatment显示文摘Flexible bioelectronics,including wearable and implantable electronics,have revolutionized the way of human-machine interaction due to the fact that they can provide natural and seamless interactions with humans and keep stable and durable at strained states.As sensor elements or biomimetic actuators,flexible bioelectronics can dynamically sense and monitor physiological signals,reveal real-time physical health information and provide timely precise stimulations or treatments.Thus,the flexible bioelectronics are playing increasingly important roles in human-health monitoring and disease treatment,which will significantly change the future of healthcare as well as our relationships with electronics.This review summarizes recent major progress in the development of flexible substrates or encapsulation materials,sensors,circuits and energy-autonomous powers toward digital healthcare monitoring,emphasizing its role in biomedical applications in vivo and problems in practical applications.A future perspective into the challenges and opportunities in emerging flexible bioelectronics designs for the next-generation healthcare monitoring systems is also presented. | Guang Yao Chenhui Yin Qian Wang Tianyao Zhang Sihong Chen Chang Lu Kangning Zhao Weina Xu Taisong Pan Min Gao Yuan Lin | 2020 | Journal of Materiomics2020，6，2： | 2 |
| 11 | Effect of IrO2 loading on RuO2-IrO2-TiO2 anodes: A study of microstructure and working life for the chlorine evolution reaction显示文摘 | Zeng Yi Chen Kangning Wu Wei | 2007 | Ceramics International2007，33，6： | 1 |
| 12 | Measurements and correlation of liquid–liquid equilibrium data for the ternary(methyl tert-butyl ketone + o, m, p-benzenediol + water)system at(333.2, 343.2 and 353.2) K显示文摘In this work, liquid–liquid equilibria(LLE) data for the ternary system methyl tert-butyl ketone(MTBK)+ o, m,p-benzenediol + water were investigated at 333.2 K, 343.2 K and 353.2 K under 101.3 kPa. The performance of MTBK to extract o, m, p-benzenediol from wastewaters was estimated by partition coefficients and separation factors. The Hand and Bachman equations were both applied to check the reliability of the experimental LLE data. Furthermore, the Non-Random Two-Liquid(NRTL) and Universal Quasi Chemical(UNIQUAC) models were applied to correlate the measured LLE data. The results showed a good agreement with the determined ternary LLE data with the root-mean-square error(RMSE) values below 0.71%. MTBK was proved to be a promising extracting agent in extracting benzenediols from effluents. | Kangning Xiong Shuai Shen Youchang Wang Yun Chen | 2019 | Chinese Journal of Chemical Engineering2019，27，4： | 1 |
| 13 | Response of soil respiration to environmental and photosynthetic factors in different subalpine forest-cover types in a loess alpine hilly region显示文摘Soil respiration(Rs)is important for transport-ing or fixing carbon dioxide from the atmosphere,and even diminutive variations can profoundly influence the carbon cycle.However,the R_(s) dynamics in a loess alpine hilly region with representative sensitivity to climate change and fragile ecology remains poorly understood.This study investigated the correlation and degree of control between R_(s) and its photosynthetic and environmental factors in five subalpine forest cover types.We examined the correlations between R_(s) and variables temperature(T_(10)) and soil moisture content at 10 cm depth(W_(10)),net photosynthetic rate(P_(n))and soil properties to establish multiple models,and the variables were measured for diurnal and monthly vari-ations from September 2018 to August 2019.The results showed that soil physical factors are not the main drivers of R_(s) dynamics at the diel scale;however,the trend in the monthly variation in R_(s) was consistent with that of T_(10)and P_(n).Further,R_(s) was significantly affected by pH,providing further evidence that coniferous forest leaves contribute to soil acidification,thus reducing R_(s).Significant exponential and linear correlations were established between R_(s) and T_(10)and W_(10),respectively,and R_(s) was positively correlated with P_(n).Accordingly,we established a two-factor model and a three-factor model,and the correlation coefficients(R_(2))was improved to different degrees compared with models based only on T_(10) and W_(10).Moreover,temperature sensitivity(Q_(10))was the highest in the secondary forest and lowest in the Larix principis-rupprechtii forest.Our findings suggest that the control of R_(s) by the environment(moisture and tempera-ture)and photosynthesis,which are interactive or comple-mentary effects,may influence spatial and temporal homeo-stasis in the region and showed that the models appropriately described the dynamic variation in R_(s) and the carbon cycle in different forest covers.In addition,total phosphorus(TP)and total potassium(TK)significantly affected the dynamic changes in R_(s).In summary,interannual and seasonal variations in forest R_(s) at multiple scales and the response forces of related ecophysiological factors,especially the interactive driving effects of soil temperature,soil moisture and photo-synthesis,were clarified,thus representing an important step in predicting the impact of climate change and formulating forest carbon management policies. | Yuanhang Li Sha Lin Qi Chen Xinyao Ma Shuaijun Wang Kangning He | 2022 | Journal of Forestry Research2022，33，2： | 1 |
| 14 | Salt effect on the liquid–liquid equilibrium of the ternary (water + phenol + methyl isobutyl ketone) system: Experimental data and correlation显示文摘The effects of NaCl, KCl and Na_2SO_4 on the liquid–liquid equilibrium(LLE) data for the ternary system, water+ phenol + methyl isobutyl ketone, were determined at 0.101 MPa and 333.15 K and 343.15 K.The nonrandom two-liquid(NRTL) model was used to correlate the experimental data and to yield corresponding binary interaction parameters for these salt containing systems.The Hand and Othmer–Tobias equations were used to confirm the dependability of the determined LLE data in this work.Distribution coefficient and selectivity were used to evaluate the extraction performance of methyl isobutyl ketone with the existence of salt.The magnitude of salt effect on the water + phenol + methyl isobutyl ketone(MIBK) system is in the following order: Na_2SO_4>NaCl>KCl. | Yun Chen Kangning Xiong Shuai Shen Huimin Wang Shaoming Zhou Libo Li | 2019 | Chinese Journal of Chemical Engineering2019，27，1： | 1 |
| 15 | Are services delivered b community health centers more cost- effective?Evidence from urban China显示文摘 | Jiang Hongli Chen Wen B: Kangning | 2009 | Heal@ Economics2009，，18： | 1 |
| 16 | The effect of the shear flow on directional solidification of SCN-3wt% Salol alloy显示文摘The directional solidification process of SCN-3wt%Salol transparent alloy is investigated in the presence of the shear flow at the liquid-solid interface.It is found that the shear flow induces a stabilizing effect on planar interface.At higher pulling rates,oscillation of the growth pattern together with fluctuation of the growth velocity takes place.With the increase of the pulling rate,the interface growth pattern transits from'planar-cellular'oscillation to'cellular-dendritic'oscillation,and the periodicity increases.The modification of the growth pattern is due to the effect of the shear flow on solute distribution,and the time and history dependent character of interface morphology evolution also plays an important role in the formation of the oscillating growth pattern. | WANG JianYuan CHEN ChangLe WANG KangNing JIN KeXin | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，5： | 1 |
| 17 | Screening proteins that interact with mutant superoxide dismutase 1 from familial amyotrophic lateral sclerosis using a yeast two-hybrid system显示文摘The present study screened a human fetal brain cDNA library to find the proteins that interact with mutant superoxide dismutase 1 (SOD1) using a yeast two-hybrid system. Using BLAST software, 15 real proteins which interacted with mutant SOD1 were obtained, including 8 known proteins (protein tyrosine-phosphatase non-receptor type 2, TBC1D4, protein kinase family, splicing factor, arginine/serine-rich 2, SRC protein tyrosine kinase Fyn, β-sarcoglycan; glycine receptor α2, micro-tubule associated protein/microtubule affinity-regulating kinase 1, ferritin H chain), and 7 unknown proteins. Results demonstrated interaction of mutant SOD1 with microtubule associated pro-tein/microtubule affinity-regulating kinase 1 and β-sarcoglycan. | Guisheng Chen Shugui Shi Lusi Li Kangning Chen Ju HU Zhenhua Zhou Jun WU GaoxingLuo ShunzongYuan Xu Peng | 2011 | Neural Regeneration Research2011，6，26： | 0 |
| 18 | All-perfluoropolymer,nonlinear stability-assisted monolithic surface combines topology-specific superwettability with ultradurability显示文摘Developing versatile and robust surfaces that mimic the skins of living beings to regulate air/liquid/solid matter is critical for many bioinspired applications.Despite notable achievements,such as in the case of developing robust superhydrophobic surfaces,it remains elusive to realize simultaneously topology-specific superwettability and multipronged durability owing to their inherent tradeoff and the lack of a scalable fabrication method.Here,we present a largely unexplored strategy of preparing an all-perfluoropolymer(Teflon),nonlinear stability-assisted monolithic surface for efficient regulating matters. | Wanbo Li Chiu-wing Chan Zeyu Li Sin-Yung Siu Siyu Chen Han Sun Zeyu Liu Yisu Wang Chong Hu Nicola Maria Pugno Richard N.Zare Hongkai Wu Kangning Ren | 2023 | The Innovation2023，4，2： | 0 |
| 19 | 能量匮乏条件下Snf1-Mec1-Atg1通过控制线粒体呼吸作用调控细胞自噬的发生显示文摘文章简介m TOR和AMPK两个信号分子在细胞自噬的发生过程中扮演着非常重要的调控作用。近年来,人们对于m TOR信号分子如何调控细胞自噬的研究比较清楚,但是对于在能量匮乏条件下,AMPK信号分子如何调控细胞自噬的发生尚不清楚。 | Cong Yi Jingjing Tong Puzhong Lu Yizheng Wang Jinxie Zhang Chen Sun Kangning Yuan Renyu Xue Bing Zou Nianzhong Li Shuhua Xiao Chong Dai Yuwei Huang Liling Xu Lin Li She Chen Di Miao Haiteng Deng Hongliang Li 俞立 | 2018 | 科学新闻2018，0，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员