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| 1 | Consensus on the application of negative pressure wound therapy of diabetic foot wounds显示文摘Because China is becoming an aging society,the incidence of diabetes and diabetic foot have been increasing.Diabetic foot has become one of the main health-related killers due to its high disability and mortality rates.Negative pressure wound therapy(NPWT)is one of the most effective techniques for the treatment of diabetic foot wounds and great progress,both in terms of research and its clinical application,has been made in the last 20 years of its development.However,due to the complex pathogenesis and management of diabetic foot,irregular application of NPWT often leads to complications,such as infection,bleeding and necrosis,that seriously affect its treatment outcomes.In 2020,under the leadership of Burns,Trauma and Tissue Repair Committee of the Cross-Straits Medicine Exchange Association,the writing group for‘Consensus on the application of negative pressure wound therapy of diabetic foot wounds’was established with the participation of scholars from the specialized areas of burns,endocrinology,vascular surgery,orthopedics and wound repair.Drawing on evidence-based practice suggested by the latest clinical research,this consensus proposes the best clinical practice guidelines for the application and prognostic evaluation of NPWT for diabetic foot.The consensus aims to support the formation of standardized treatment schemes that clinicians can refer to when treating cases of diabetic foot. | Shizhao Ji Xiaobin Liu Jie Huang Junmin Bao Zhaohong Chen Chunmao Han Daifeng Hao Jingsong Hong Dahai Hu Yufeng Jiang Shang Ju Hongye Li Zongyu Li Guangping Liang Yan Liu Gaoxing Luo Guozhong Lv Xingwu Ran Zhongmin Shi Juyu Tang Aiping Wang Guangyi Wang Jiangning Wang Xin Wang Bing Wen Jun Wu Hailin Xu Maojin Xu Xiaofei Ye Liangxi Yuan Yi Zhang Shichu Xiao Zhaofan Xia | 2021 | Burns & Trauma2021，9，1： | 17 |
| 2 | Analysis of the CDR3 Length Repertoire and the Diversity of TCRα Chain in Human Peripheral Blood T Lymphocytes显示文摘Analysis of complementarity determining region 3 (CDR3) length of T lymphocyte receptors (TCRs) by immunoscope spectratyping technique has been used successfully to investigate the diversity of TCR in autoimmune diseases and infection diseases. In this study, we investigated the patterns of CDR3 length distribution for all 32 TCR AV gene families in human peripheral blood lymphocytes of four normal volunteers by the immunoscope spectratyping technique. It was found that PCR products exhibited an obscure band on 1.5% agarose gel electrophoresis. Each TCR AV family exhibited more than 8 bands on 6% sequencing gel electrophoresis. The CDR3 spectratyping of all TCR AV families showed a standard Gaussian distribution with different CDR3 length, and the expression frequency of CDR3 was similar among the gene families. Most of CDR3 in TCR AV family recombine in frame. However, some of the CDR3 showed out-of frame gene rearrangement. Additionally, we found that in some of TCR AV families there were 18 amino acid discrepancies between the longest CDR3 and shortest CDR3. These results may be helpful to further study the recombination mechanism of human TCR genes, the TCR CDR3 gene repertoire, and the repertoire drift in health people and disease state. | Xinsheng Yao Ying Diao Wanbang Sun Junmin Luo Ming Qin Xianying Tang | 2007 | Cellular & Molecular Immunology2007，4，3： | 10 |
| 3 | Selenium deficiency induces spleen pathological changes in pigs by decreasing selenoprotein expression,evoking oxidative stress,and activating inflammation and apoptosis显示文摘Background:The immune system is one aspect of health that is affected by dietary selenium(Se)levels and selenoprotein expression.Spleen is an important immune organ of the body,which is directly involved in cellular immunity.However,there are limited reports on Se levels and spleen health.Therefore,this study established a Se-deficient pig model to investigate the mechanism of Se deficiency-induced splenic pathogenesis.Methods:Twenty-four pure line castrated male Yorkshire pigs(45 days old,12.50±1.32 kg,12 full-sibling pairs)were divided into two equal groups and fed Se-deficient diet(0.007 mg Se/kg)or Se-adequate diet(0.3 mg Se/kg)for 16 weeks.At the end of the trial,blood and spleen were collected to assay for erythroid parameters,the osmotic fragility of erythrocytes,the spleen index,histology,terminal deoxynucleotidyl transferase nick-end labeling(TUNEL)staining,Se concentrations,the selenogenome,redox status,and signaling related inflammation and apoptosis.Results:Dietary Se deficiency decreased the erythroid parameters and increased the number of osmotically fragile erythrocytes(P<0.05).The spleen index did not change,but hematoxylin and eosin and TUNEL staining indicated that the white pulp decreased,the red pulp increased,and splenocyte apoptosis occurred in the Se deficient group.Se deficiency decreased the Se concentration and selenoprotein expression in the spleen(P<0.05),blocked the glutathione and thioredoxin antioxidant systems,and led to redox imbalance.Se deficiency activated the NF-κB and HIF-1αtranscription factors,thus increasing pro-inflammatory cytokines(IL-1β,IL-6,IL-8,IL-17,and TNF-α),decreasing anti-inflammatory cytokines(IL-10,IL-13,and TGF-β)and increasing expression of the downstream genes COX-2 and iNOS(P<0.05),which in turn induced inflammation.In addition,Se-deficiency induced apoptosis through the mitochondrial pathway,upregulated apoptotic genes(Caspase3,Caspase8,and Bak),and downregulated antiapoptotic genes(Bcl-2)(P<0.05)at the mRNA level,thus verifying the results of TUNEL staining.Conclusions:These results indicated that Se deficiency induces spleen injury through the regulation of selenoproteins,oxidative stress,inflammation and apoptosis. | Shuang Li Wenjuan Sun Kai Zhang Jiawei Zhu Xueting Jia Xiaoqing Guo Qingyu Zhao Chaohua Tang Jingdong Yin Junmin Zhang | 2021 | Journal of Animal Science and Biotechnology2021，12，4： | 4 |
| 4 | Preparation of N-Doped Bi_2WO_6 Microspheres for Efficient Visible Light-Induced Photocatalysis显示文摘The N-doped bismuth tungstate(Bi_2WO_6) photocatalysts with high visible light activity were prepared by the hydrothermal method using urea as a nitrogen source.The as-prepared N-doped Bi_2WO_6 samples were characterized by X-ray diffraction,scanning electron microscopy,specific surface area,photocurrent analysis,and UV-Vis diffuse reflectrance spectroscopy.The photocatalytic activity was evaluated by photocatalytic degradation of rhodamine B(RhB)solution under visible light irradiation.The photocatalytic mechanisms were analyzed by active species trapping experiments which revealed that the holes were the main active species of N-doped Bi_2WO_6 products in aqueous solution under visible light irradiation,rather than OH and O_2^-.With the assistance of H_2O_2,the photocatalytic activity for degradation of RhB could be further improved because H_2O_2 reacted with conduction band electrons to generate more hydroxyl radicals. | Bolin Tang Guohua Jiang Zhen Wei Xia Li Xiaohong Wang Tengteng Jiang Wenxing Chen Junmin Wan | 2014 | Acta Metallurgica Sinica(English Letters)2014，27，1： | 4 |
| 5 | Structural elucidation of a neutral fucogalactan from the mycelium of coprinus comatus 显示文摘 | FAN Junmin ZHANG Jingsong TANG Qingjiu | 2006 | Carbohydr Res2006，341，9： | 1 |
| 6 | Molecular cloning and characterization of chemokinc-like factor 1 ( CKLF1 ), a novel human eytnkine with unique structure and potential ehenaotaetie activity显示文摘 | Han Wenling Lou Yaxin Tang Junmin | 2001 | Biochem J2001，357，： | 1 |
| 7 | Ultrasmall Fe<sub>3</sub>O<sub>4</sub> Nanoparticle/MoS<sub>2</sub> Nanosheet Composites with Superior Performances for Lithium Ion Batteries显示文摘 | Yu Chen Bohang Song Xiaosheng Tang Li Lu Junmin Xue | 2014 | Small2014，，8： | 1 |
| 8 | Adaptive Synchronization of Nonlinearly Parameterized Complex Dynamical Networks with Unknown Time-Varying Parameters显示文摘 | Wang Tengfei Li Junmin Tang Shu | 2012 | Mathematical Problems in Engineering2012，2012，59： | 1 |
| 9 | Molecular cloning and characterization of chemokine-like factor 1(CKLF1), a novel human cytokine with unique structure and potential chemotatic activity显示文摘 | Wenling HAN Yaxin LOU Junmin TANG | 2001 | Biochem J2001，357，1： | 1 |
| 10 | Molecular cloning and characterization of chemokine-like factor 1 ( CKLF1 ), a novel human cytokine with unique structure and potential chemotactic activity 显示文摘 | Han Wenling Lou Yaxin Tang Junmin | 2001 | Biochemistry2001，57，1： | 1 |
| 11 | Molecular cloning and characterization of chemokine-like factor 1 (CKLF1), a novel human cytokine with unique structure and potential chemotactic activity显示文摘 | Wenling Han Yaxin Lou Junmin Tang | 2001 | Biochem J2001，357，： | 1 |
| 12 | Molecular clonging and characterization of chemokine-like factor 1 (CKLF-1), a novel human cytokine with unique structure and potential chemotactic activity显示文摘 | Wenling Han Yanxin Lou Junmin Tang | 2001 | Biochem J2001，357，： | 1 |
| 13 | Molecular cloning and characterization of chemokine-like factorl ( CKLF ), a novel human cytekine with unique structure and potential chemotactic activity显示文摘 | Han Wenling Lou Yaxin Tang Junmin | 2001 | Biochem J2001，357，4： | 1 |
| 14 | Molecular clonging and characterization of chemokine, like factor 1( CKLF - 1 ), a novel human cytokine with unique structure and potential chemotactic activity显示文摘 | Wenling Hart Yanxin Lou Junmin Tang | 2001 | Biochem J2001，357，： | 1 |
| 15 | Structural elucidation of a neutral fucogalactan from the mycelium of Coprinus comatus显示文摘 | Fan Junmin Zhang Jingsong Tang Qingjiu Liu Yanfang Zhang Anqiang Pan Yingjie | 2006 | Carbohydrate Research2006，341，9： | 1 |
| 16 | A novel CyclinE/CyclinA-CDK Inhibitor targets p27 Kip1 degradation, cell cycle progression and cell survival: Implications in cancer therapy显示文摘 | Lu Dai Yuqing Liu Junyang Liu Xiaoming Wen ZhengShuang Xu Zhuo Wang Hong Sun Shoubin Tang Anita R. Maguire Junmin Quan Hui Zhang Tao Ye | 2013 | Cancer Letters2013，，1： | 1 |
| 17 | A novel CyclinE/CyclinA-CDK Inhibitor targets p27 Kip1 degradation, cell cycle progression and cell survival: Implications in cancer therapy显示文摘 | Lu Dai Yuqing Liu Junyang Liu Xiaoming Wen ZhengShuang Xu Zhuo Wang Hong Sun Shoubin Tang Anita R. Maguire Junmin Quan Hui Zhang Tao Ye | 2013 | Cancer Letters2013，，1： | 1 |
| 18 | A novel CyclinE/CyclinA-CDK Inhibitor targets p27 Kip1 degradation, cell cycle progression and cell survival: Implications in cancer therapy显示文摘 | Lu Dai Yuqing Liu Junyang Liu Xiaoming Wen ZhengShuang Xu Zhuo Wang Hong Sun Shoubin Tang Anita R. Maguire Junmin Quan Hui Zhang Tao Ye | 2013 | Cancer Letters2013，，1： | 1 |
| 19 | Random coverings of the circle with i.i.d.centers显示文摘Consider the random intervals In(ω):=(ωn-ln/2,ωn+ln/2)(mod 1) with their centers ωn being i.i.d.but not necessary uniformly distributed on the circle T = R /Z and with their lengths decreasing to zero.Using the dimension theory in dynamical systems,we give conditions on which the circle is finitely or infinitely often covered by intervals In(ω)}n≥1. | TANG JunMin | 2012 | Science China Mathematics2012，55，6： | 1 |
| 20 | Molecular cloning and characterization of chemokine-like factor 1 (CKLF1),a novel human cytokine with unique structure and potential chemotactic activity显示文摘 | Han Wenling Lou Yaxin Tang Junmin | 2001 | Biochem J2001，357，： | 1 |
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