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| 1 | A novel bioremediation strategy for petroleum hydrocarbon pollutants using salt tolerant Corynebacterium variabile HRJ4 and biochar显示文摘The present work aimed to develop a novel strategy to bioremediate the petroleum hydrocarbon contaminants in the environment.Salt tolerant bacterium was isolated from Dagang oilfield,China and identified as Corynebacterium variabile HRJ4 based on 16 S r RNA gene sequence analysis.The bacterium had a high salt tolerant capability and biochar was developed as carrier for the bacterium.The bacteria with biochar were most effective in degradation of n-alkanes(C16,C18,C19,C26,C28) and polycyclic aromatic hydrocarbons(NAP,PYR) mixture.The result demonstrated that immobilization of C.variabile HRJ4 with biochar showed higher degradation of total petroleum hydrocarbons(THPs) up to 78.9%after 7-day of incubation as compared to the free leaving bacteria.The approach of this study will be helpful in clean-up of petroleum-contamination in the environments through bioremediation process using eco-friendly and cost effective materials like biochar. | Hairong Zhang Jingchun Tang Lin Wang Juncheng Liu Ranjit Gajanan Gurav Kejing Sun | 2016 | Journal of Environmental Sciences2016，28，9： | 25 |
| 2 | Current situation and trend of marine data buoy and monitoring network technology of China显示文摘Marine data buoy can provide a long-term, continuous, real-time, reliable data of ocean observation in a variety of complex marine environment. It is one of the most reliable, most effective and important means of ocean monitoring technology. In this paper, the classification, main theory and technology system of marine data buoy are summarized. The typical technological breakthrough of the development of marine data buoy in recent years is summarized. The composition and application of marine monitoring network in China was introduced, and the gap between the technology of China's marine data buoy and the international advanced countries is compared.Combined on the situation and demand of China's current situation and needs, the development trend of marine data buoy and buoy monitoring network are expected. | WANG Juncheng WANG Zhongqiu WANG Yiming LIU Shixuan LI Yunzhou | 2016 | Acta Oceanologica Sinica2016，35，2： | 11 |
| 3 | A comparative study on the levels of serum cytokines and cortisol among post-traumatic stress disorder patients of Li and Han ethnicities in Hainan显示文摘 | Chen Tao Guo Min Gao Yunsuo Chen Feng Guo Juncheng Liu Tao Wu Duoyu Jiang Xianglin | 2014 | Chinese Medical Journal2014，，15： | 8 |
| 4 | Genetic Polymorphisms in the Precursor MicroRNA Flanking Region and Non-Small Cell Lung Cancer Survival显示文摘 | Hu, Zhibin Shu, Yongqian Chen, Yijiang Chen, Jiaping Dong, Jing Liu, Yao Pan, Shiyang Xu, Lin Xu, Jing Wang, Yi Dai , Juncheng Ma, Hongxia Jin, Guangfu Shen,Hongbing | 2011 | 南京医科大学学报(自然科学版)2011，31，6： | 8 |
| 5 | Prognostic assessment of apoptotic gene polymorphisms in non-small cell lung cancer in Chinese显示文摘Apoptosis plays a key role in inhibiting tumor growth, progression and resistance to anti-tumor therapy. We hypothesized that genetic variants in apoptotic genes may affect the prognosis of lung cancer. To test this hypothesis, we selected 38 potentially functional single nucleotide polymorphisms (SNPs) from 12 genes (BAX, BCL2, BID, CASP3, CASP6, CASP7, CASP8, CASP9, CASP10, FAS, FASLG and MCL1) involved in apoptosis to assess their prognostic significance in lung cancer in a Chinese case cohort with 568 non-small cell lung cancer (NSCLC) patients. Thirty-five SNPs passing quality control underwent association analyses, 11 of which were shown to be significantly associated with NSCLC survival (P<0.05). After Cox stepwise regression analyses, 3 SNPs were independently associated with the outcome of NSCLC (BID rs8190315: P=0.003; CASP9 rs4645981: P=0.007 and FAS rs1800682: P=0.016). A favorable survival of NSCLC was significantly associated with the genotypes of BID rs8190315 AG/GG (adjusted HR=0.65, 95% CI: 0.49-0.88), CASP9 rs4645981 AA (HR=0.22, 95% CI: 0.07-0.69) and FAS rs1800682 GG (adjusted HR=0.67, 95% CI: 0.46-0.97). Time-dependent receptor operation curve (ROC) analysis revealed that the area under curve (AUC) at year 5 was significantly increased from 0.762 to 0.819 after adding the risk score of these 3 SNPs to the clinical risk score. The remaining 32 SNPs were not significantly associated with NSCLC prognosis after adjustment for these 3 SNPs. These findings indicate that BID rs8190315, CASP9 rs4645981 and FAS rs1800682 polymorphisms in the apoptotic pathway may be involved in the prognosis of NSCLC in the Chinese population. | Songyu Cao Cheng Wang Xinen Huang Juncheng Dai Lingmin Hu Yao Liu Jiaping Chen Hongxia Ma Guangfu Jin Zhibin Hu Lin Xu Hongbing Shen | 2013 | The Journal of Biomedical Research2013，27，3： | 6 |
| 6 | Proteomic identification of new diagnostic biomarkers of early-stage cutaneousmycosis fungoides显示文摘Dear editor,Mycosis fungoides(MF),the most common subtype of cutaneous T cell lymphoma,is a rare disease[1,2].Patients with early-stageMF have a 5-year overall survival between 88%and 100%[3].In patients with advanced MF,the skin may present with tumors and erythroderma,and the median survival of patients with lymph node and visceral metastasis is 13 months[4].Therefore,it is important to achieve an early diagnosis to improve prognosis[5]. | Ling Leng Zhaorui Liu Jie Ma Shiyu Zhang Yukun Wang Luye Lv Yunping Zhu Dunqin Gao Yujie Wang Juncheng Wang Yuehua Liu Jie Liu | 2022 | Cancer Communications2022，42，6： | 4 |
| 7 | Serum semaphorin 4C as a diagnostic biomarker in breast cancer:A multicenter retrospective study显示文摘Background:To date,there is no approved blood-based biomarker for breast cancer detection.Herein,we aimed to assess semaphorin 4C(SEMA4C),a pivotal protein involved in breast cancer progression,as a serum diagnostic biomarker.Methods:We included 6,213 consecutive inpatients from Tongji Hospital,Qilu Hospital,and Hubei Cancer Hospital.Training cohort and two validation cohorts were introduced for diagnostic exploration and validation.A pan-cancer cohort was used to independently explore the diagnostic potential of SEMA4C among solid tumors.Breast cancer patients who underwent mass excision prior to modified radical mastectomy were also analyzed.We hypothesized that increased pretreatment serum SEMA4C levels,measured using optimized in-house enzymelinked immunosorbent assay kits,could detect breast cancer.The endpoints were diagnostic performance,including area under the receiver operating characteristic curve(AUC),sensitivity,and specificity.Post-surgery pathological diagnosis was the reference standard and breast cancer staging followed the TNM classification.There was no restriction on disease stage for eligibilities.Results:We included 2667 inpatients with breast lesions,2378 patients with other solid tumors,and 1168 healthy participants.Specifically,118 patients with breast cancer were diagnosed with stage 0(5.71%),620 with stage I(30.00%),966 with stage II(46.73%),217 with stage III(10.50%),and 8 with stage IV(0.39%).Patients with breast cancer had significantly higher serum SEMA4C levels than benign breast tumor patients and normal controls(P<0.001).Elevated serum SEMA4C levels had AUC of 0.920(95%confidence interval[CI]:0.900–0.941)and 0.932(95%CI:0.911–0.953)for breast cancer detection in the two validation cohorts.The AUCs for detecting early-stage breast cancer(n=366)and ductal carcinoma in situ(n=85)were 0.931(95%CI:0.916–0.946)and 0.879(95%CI:0.832–0.925),respectively.Serum SEMA4C levels significantly decreased after surgery,and the reduction was more striking after modified radical mastectomy,compared with mass excision(P<0.001).The positive rate of enhanced serum SEMA4C levels was 84.77%for breast cancer and below 20.75%for the other 14 solid tumors.Conclusions:Serum SEMA4C demonstrated promising potential as a candidate biomarker for breast cancer diagnosis.However,validation in prospective settings and by other study groups is warranted. | Ya Wang Long Qiao Jie Yang Xiong Li Yaqi Duan Jiahao Liu Shaoqi Chen Huayi Li Dan Liu Tian Fang Jingjing Ma Xiaoting Li Fei Ye Junxiang Wan Juncheng Wei Qin Xu Ensong Guo Ping Jin Mingfu Wu Lin Zhang Yun Xia Yaqun Wu Jun Shao Yaojun Feng Qing Zhang Zongyuan Yang Gang Chen Qinghua Zhang Xingrui Li Shixuan Wang Junbo Hu Xiaoyun Wang Mona P.Tan Kazuaki Takabe Beihua Kong Qifeng Yang Ding Ma Qinglei Gao | 2021 | Cancer Communications2021，41，12： | 3 |
| 8 | Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma显示文摘Although genome-wide association studies have identified more than eighty genetic variants associated with non-small cell lung cancer(NSCLC)risk,biological mechanisms of these variants remain largely unknown.By integrating a large-scale genotype data of 15581 lung adenocarcinoma(AD)cases,8350 squamous cell carcinoma(SqCC)cases,and 27355 controls,as well as multiple transcriptome and epigenomic databases,we conducted histology-specific meta-analyses and functional annotations of both reported and novel susceptibility variants.We identified 3064 credible risk variants for NSCLC,which were overrepresented in enhancer-like and promoter-like histone modification peaks as well as DNase I hypersensitive sites.Transcription factor enrichment analysis revealed that USF1 was AD-specific while CREB1 was SqCC-specific.Functional annotation and genebased analysis implicated 894 target genes,including 274 specifics for AD and 123 for SqCC,which were overrepresented in somatic driver genes(ER=1.95,P=0.005).Pathway enrichment analysis and Gene-Set Enrichment Analysis revealed that AD genes were primarily involved in immune-related pathways,while SqCC genes were homologous recombination deficiency related.Our results illustrate the molecular basis of both wellstudied and new susceptibility loci of NSCLC,providing not only novel insights into the genetic heterogeneity between AD and SqCC but also a set of plausible gene targets for post-GWAS functional experiments. | Na Qin Yuancheng Li Cheng Wang Meng Zhu Juncheng Dai Tongtong Hong Demetrius Albanes Stephen Lam Adonina Tardon Chu Chen Gary Goodman Stig EBojesen Maria Teresa Landi Mattias Johansson Angela Risch H-Erich Wichmann Heike Bickeboller Gadi Rennert Susanne Arnold Paul Brennan John KField Sanjay Shete Loic Le Marchand Olle Melander Hans Brunnstrom Geoffrey Liu Rayjean JHung Angeline Andrew Lambertus AKiemeney Shan Zienolddiny Kjell Grankvist Mikael Johansson Neil Caporaso Penella Woll Philip Lazarus Matthew BSchabath Melinda CAldrich Victoria LStevens Guangfu Jin David CChristiani Zhibin Hu Christopher IAmos Hongxia Ma Hongbing Shen | 2021 | Frontiers of Medicine2021，15，2： | 3 |
| 9 | Highly green fluorescent Nb2C MXene quantum dots for Cu2+ion sensing and cell imaging显示文摘Niobium carbide MXene quantum dots(Nb2 C MQDs)derived from 2 D Nb2 CTx(MXene)are the rising-star material recently.Herein,a sulfur and nitrogen co-doped Nb2 C MQDs(S,N-MQDs)were synthesized through a hydrothermal method.The obtained Nb2 C MQDs have excellent green fluorescence with a quantum yield(QY)of 17.25%.In addition,they exhibited excitatio n-dependent photoluminescence,antiphotobleaching and dispersion stability.They emit light at 520 nm when excited at 390 nm.The Nb2 C MQDs could be successfully applied to copper ion detection with detection limit of 2μmol/L and Caco-2 cells imaging. | Xiang Yan Junfei Ma Kaixuan Yu Jiapeng Li Lei Yang Jjiaqi Liu Juncheng Wang Lulu Cai | 2020 | Chinese Chemical Letters2020，31，12： | 3 |
| 10 | Role of surface warming in the northward shift of tropical cyclone tracks over the South China Sea in November显示文摘Tropical cyclones(TCs) formed in the Northwest Pacific Ocean(NWP) can cross the South China Sea(SCS)sometimes. It is found that the TC tracks in the SCS in November are shifted to the north after 1980 compared with those before 1980. Both data analyses and numerical simulations show that the surface warming in the SCS may contribute to this more northward shift. The warming produces a cyclonic atmosphere circulation anomaly in the northwestern SCS and an associated southerly in the central SCS steering the TCs to the north. | SUN Jia WANG Guihua ZUO Juncheng LING Zheng LIU Dahai | 2017 | Acta Oceanologica Sinica2017，36，5： | 2 |
| 11 | Ultrabroadband and multiband infrared/terahertz photodetectors with high sensitivity显示文摘Broadband response is pursued in both infrared(IR)and terahertz(THz)detection technologies,which find their applications in both terrestrial and astronomical realms.Herein,we report an ultrabroadband and multiband IR/THz detector based on blocked-impurity-band detecting principle.The detectors are prepared by implanting phosphorus into germanium(Ge:P),where photoresponses with a P impurity band,a self-interstitial defect band,and a vacancy-P(V-P)pair defect band are realized simultaneously.The response spectra of the detectors show ultrabroad and dual response bands in a range of 3-28μm(IR band)and 40-165μm(THz band),respectively.Additionally,a tiny mid-IR(MIR)band within 3-4.2μm is embedded in the IR band.The THz band arises from the P impurity band,whereas the IR and the MIR bands are ascribed to the two defect bands.At150 m V and 4.5 K,the peak detectivities of the three bands are obtained as 2.9×10^(12) Jones(at 3.9μm),6.8×10^(12) Jones(at 16.3μm),and 9.9×10^(12) Jones(at 116.5μm),respectively.The impressive coverage andsensitivity of the detectors are promising for applications in IR and THz detection technologies. | JIAQI ZHU HE ZHU MENGJUAN LIU YAO WANG HANLUN XU NASIR ALI HUIYONG DENG ZHIYONG TAN JUNCHENG CAO NING DAI HUIZHEN WU | 2021 | Photonics Research2021，9，11： | 2 |
| 12 | Association of assisted reproductive technology, germline de novo mutations and congenital heart defects in a prospective birth cohort study显示文摘Emerging evidence suggests that children conceived through assisted reproductive technology(ART)have a higher risk of congenital heart defects(CHDs)even when there is no family history.De novo mutation(DNM)is a well-known cause of sporadic congenital diseases;however,whether ART procedures increase the number of germline DNM(gDNM)has not yet been well studied.Here,we performed whole-genome sequencing of 1137 individuals from 160 families conceived through ART and 205 families conceived spontaneously.Children conceived via ART carried 4.59 more gDNMs than children conceived spontaneously,including 332 paternal and 1.26 maternal DNMs,after correcting for parental age at conception,cigarette smoking,alcohol drinking,and exercise behaviors.Paternal DNMs in offspring conceived via ART are characterized by C>T substitutions at CpG sites,which potentially affect protein-coding genes and are significantly associated with the increased risk of CHD.In addition,the accumulation of non-coding functional mutations was independently associated with CHD and 87.9% of the mutations were originated from the father.Among ART offspring,infertility of the father was associated with elevated paternal DNMs;usage of both recombinant and urinary follicle-stimulating hormone and high-dosage human chorionic gonadotropin trigger was associated with an increase of maternal DNMs.In sum,the increased gDNMs in offspring conceived by ART were primarily originated from fathers,indicating that ART itself may not be a major reason for the accumulation of gDNMs.Our findings emphasize the importance of evaluating the germline status of the fathers in families with the use of ART. | Cheng Wang Hong Lv Xiufeng Ling Hong Li Feiyang Diao Juncheng Dai Jiangbo Du Ting Chen Qi Xi Yang Zhao Kun Zhou Bo Xu Xiumei Han Xiaoyu Liu Meijuan Peng Congcong Chen Shiyao Tao Lei Huang Cong Liu Mingyang Wen Yangqian Jiang Tao Jiang Chuncheng Lu Wei Wu Di Wu Minjian Chen Yuan Lin Xuejiang Guo Ran Huo Jiayin Liu Hongxia Ma Guangfu Jin Yankai Xia Jiahao Sha Hongbing Shen Zhibin Hu | 2021 | Cell Research2021，31，8： | 2 |
| 13 | Structure and Properties of PLA Composite Enhanced with Biomass Fillers from Herbaceous Plants显示文摘PLA composites containing biomass fillers from the three herbaceous plants such as reed,wheat stalk,and coco-nut fiber with length and diameter at the scale of several millimeters were prepared without using additives.The reinforcement effect on the properties of PLA/biomass filler composites is investigated.The research results show that the PLA/biomass filler composites exhibit good stiffness,flexural strength,and impact toughness.Among the three kinds of biomass fillers,reed reinforced PLA composites show optimal mechanical properties.When filled with 40%–50%reed,the flexural moduli of the composites are over 7000 MPa.Flexural strength retains at the same level of pure PLA.The notch impact strength reaches to 4.50±0.73 kJ/m^(2),which is 2.06 times higher than that of pure PLA.Furthermore,the introduction of biomass fillers increases the crystallization ability of PLA and does not increase the water absorption of the composites.This research demonstrated that PLA composites prepared with biomass fillers from the herbaceous plants(namely herb plastic composites,HPCs)is a material with good comprehensive mechanical properties while retaining the intrinsic particularity of biological sources. | Haining Na Juncheng Huang Hongguang Xu Fei Liu Liangke Xie Baoqing Zhu Jiuchen Wang Jin Zhu | 2023 | Journal of Renewable Materials2023，11，2： | 2 |
| 14 | Modeling Ekman flow during the ACRT process with marked particals 显示文摘 | LIU JUNCHENG JIE WANQI | 1998 | J Cryst Growth1998，183，： | 2 |
| 15 | Spatiotemporal Changes of Vegetation Cover in Response to Climate Change on the Tibetan Plateau显示文摘The Tibetan Plateau is one of the most important ecological barriers in China. Resolving the internal relations and dynamics ruling the association between regional vegetation and climate change is important to understand and protect the regional ecosystems. Based on vegetation, temperature and precipitation data of the Tibetan Plateau from 2001 to 2010, we analyze the spatial and temporal variations of vegetation cover over the past 10 years and discuss the vegetation response to climate change using empirical orthogonal function and singular value decomposition. Our results reveal the following:(1) vegetation cover gradually decreases from the southeast to the northwest of the Tibetan Plateau;(2) vegetation cover has increased on the Tibetan Plateau over the past 10 years, mainly in the central and eastern zones; and(3) a significant positive relationship was suggested between vegetation cover during growing season and the temperature in the entire region and with precipitation in the central and southern zones. | LI Juncheng WANG Jianrong GONG Bin GAN Xiaoli HU Weiwu LIU Weiling | 2014 | Acta Geologica Sinica(English Edition)2014，88，3： | 2 |
| 16 | Critical Transient Processes of Enhancement-mode GaN HEMTs in High-efficiency and High-reliability Applications显示文摘Wide-bandgap devices,such as silicon-carbide metal-oxide-semiconductor field-effect transistors(MOSFETs)and gallium-nitride high electron mobility transistors(HEMTs),exhibit an excellent figure of merits compared to conventional silicon devices.Challenges of applying such fast switches include accurate extraction and optimization of parasitics especially when 6high-efficiency operation,all of which require the comprehensive understanding of such switch especially its interaction with peripheral circuits.Particularly for the enhancement-mode GaN HEMTs without the intrinsic body diode,when reverse conducting,its high voltage drop causes a high dead-time loss,which has rarely a concern in silicon devices.This paper focuses on 650V/30~60A enhancement-mode GaN HEMTs provided by GaN Systems,analytically models its switching behaviors,summarizes the impact of parasitics and dead time,and applies it in two DC/DC converters.Systematic design rules are generated not only for soft switching but also for hard switching applications. | Lucas(Juncheng)Lu Guanliang Liu Kevin(Hua)Bai | 2017 | CES Transactions on Electrical Machines and Systems2017，1，3： | 2 |
| 17 | Patterns of Clay Minerals Transformation in Clay Gouge, with Examples from Revers Fault Rocks in Devonina Niqiuhe Formation in The Dayangshu Basin显示文摘The role of authigenic clay growth in clay gouge is increasingly recognized as a key to understanding the mechanics of berittle faulting and fault zone processes,including creep and seismogenesis,and providing new insights into the ongoing debate about the frictional strength of brittle fault(Haines and van der Pluijm,2012).However,neither the conditions nor the processes | MENG Jie LI Benxian ZHANG Juncheng LIU Xiaoyang | 2017 | Acta Geologica Sinica(English Edition)2017，91，S1： | 2 |
| 18 | Numerical Simulation of the Convection during ACRT显示文摘 | LIU Juncheng JIE Wanqi ZHOU Yaohe | 1997 | Progress in Natural Science1997，7，： | 1 |
| 19 | Standardization of tritiated water by the CIEMAT/NIST and TDCR methods显示文摘The activity of tritiated water has been standardized by two liquid scintillation counting methods:The CIEMAT/NIST method with the54Mn-standard efficiency tracing and the triple-to-double coincidence ratio(TDCR)method.The samples were prepared with Ultima Gold TM AB liquid scintillation cocktail in low-potassium glass vials.In the application of the CIEMAT/NIST method,the computer program EMILIA was used to calculate the efficiency of3H and54Mn according to the KL1L2L3M atomic rearrangement model.And the detection efficiency of the TDCR counter was calculated using TDCR07 code,which makes it possible to allow for the potential asymmetry between the three photomultiplier tubes.The influence of stopping power and k B factor is discussed in the paper.When a power approach is adopted for the stopping power for electrons below 1ke V and k B is chosen to be 0.0075 cm/Me V,the relative deviation will be only 0.3%between the two methods. | WU YongLe LIU HaoRan LIANG JunCheng LIU JiaCheng XIONG WenJun YUE HuiGuo LIU SenLin YANG YuanDi YUAN DaQing | 2015 | Science China(Technological Sciences)2015，58，3： | 1 |
| 20 | Genetic variants at chromosome 9p21, 10p15 and 10q22 and breast cancer susceptibility in a Chinese population显示文摘 | Jiaping Chen Yue Jiang Xiaoan Liu Zhenzhen Qin Juncheng Dai Guangfu Jin Hongxia Ma Shui Wang Xinru Wang Zhibin Hu Hongbing Shen | 2012 | Breast Cancer Research and Treatment2012，，2： | 1 |
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