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| 1 | Endoscopic removal of gastric ectopic pancreas:An initial experience with endoscopic submucosal dissection显示文摘AIM:To evaluate the therapeutic usefulness and safety of endoscopic resection in patients with gastric ectopic pancreas.METHODS:A total of eight patients with ectopic pancreas were included.All of them underwent endoscopic ultrasonography before endoscopic resection.Endo-scopic resection was performed by two methods:endo-scopic mucosal resection(EMR)by the injection-and-cut technique or endoscopic mucosal dissection(ESD).RESULTS:We planned to perform EMR in all eight cases but EMR was successful in only four cases.In the other four cases,saline spread into surrounding normal tissues and the lesions becameattened,which made it impossible to remove them by EMR.Inthose four cases,we performed ESD and removed the lesions without any complications.CONCLUSION:If conventional EMR is difficult to remove gastric ectopic pancreas,ESD is a feasible alternative method for successful removal. | Dong Yup Ryu Gwang Ha Kim Do Youn Park Bong Eun Lee Jae Hoon Cheong Dong Uk Kim Hyun Young Woo Jeong Heo Geun Am Song | 2010 | World Journal of Gastroenterology2010，16，36： | 24 |
| 2 | Multimodal imaging evaluation in staging of rectal cancer显示文摘Rectal cancer is a common cancer and a major cause of mortality in Western countries.Accurate staging is essential for determining the optimal treatment strategies and planning appropriate surgical procedures to control rectal cancer.Endorectal ultrasonography(EUS)is suitable for assessing the extent of tumor invasion,particularly in early-stage or superficial rectal cancer cases.In advanced cases with distant metastases,computed tomography(CT)is the primary approach used to evaluate the disease.Magnetic resonance imaging(MRI)is often used to assess preoperative staging and the circumferential resection margin involvement,which assists in evaluating a patient’s risk of recurrence and their optimal therapeutic strategy.Positron emission tomography(PET)-CT may be useful in detecting occult synchronous tumors or metastases at the time of initial presentation.Restaging after neoadjuvant chemoradiotherapy(CRT)remains a challenge with all modalities because it is difficult to reliably differentiate between the tumor mass and other radiation-induced changes in the images.EUS does not appear to have a useful role in post-therapeutic response assessments.Although CT is most commonly used to evaluate treatment responses,its utility for identifying and following-up metastatic lesions is limited.Preoperative high-resolution MRI in combination with diffusion-weighted imaging,and/or PET-CT could provide valuable prognostic information for rectal cancer patients with locally advanced disease receiving preoperative CRT.Based on these results,we conclude that a combination of multimodal imaging methods should be used to precisely assess the restaging of rectal cancer following CRT. | Suk Hee Heo Jin Woong Kim Sang Soo Shin Yong Yeon Jeong Heoung-Keun Kang | 2014 | World Journal of Gastroenterology2014，20，15： | 16 |
| 3 | Colonic J-pouch anal anastomosis after ultralow anterior resection with upper sphincter excision for low-lying rectal cancer显示文摘AIM: There is some evidence of functional superiority of colonic J-pouch over straight coloanal anastomosis (CAA)in ultralow anterior resection (ULAR) or intersphincteric resection. On the assumption that colonic J-pouch anal anastomosis is superior to straight CAA in ULAR with upper sphincter excision (USE: excision of the upper part of the internal sphincter) for low-lying rectal cancer, we compare functional outcome of colonic J-pouch vs the straight CAA.METHODS: Fifty patients of one hundred and thirty-three rectal cancer patients in whom lower margin of the tumors were located between 3 and 5 cm from the anal verge received ULAR including USE from September 1998 to January 2002. Patients were randomized for reconstruction using either a straight (n = 26) or a colonic J-pouch anastomosis (n = 24) with a temporary diverting-loop ileostomy. All patients were followed-up prospectively by a standardized questionnaire [Fecal Inco-ntinence Severity Index (FISI) scores and Fecal Incontinence Quality of Life (FIQL) scales].RESULTS: We found that, compared to straight anastomosis patients, the frequency of defecation was significantly lower in J-pouch anastomosis patients for 10 mo afterileostomy takedown. The FISI scores and FIQL scales were significantly better in J-pouch patients than in straight patients at both 3 and 12 mo after ileostomy takedown.Furthermore, we found that FISI scores highly correlated with FIQL scales.CONCLUSION: This study indicates that colonic J-pouch anal anastomosis decreases the severity of fecal incontinence and improves the quality of life for 10 mo after ileostomy takedown in patients undergoing ULAR with USE forlow-lying rectal cancer. | Jae-Gahb Park Min Ro Lee Seok-Byung Lim Chang Won Hong Sang Nam Yoon Sung-Bum Kang Seung Chul Heo Seung-Yong Jeong Kyu Joo Park | 2005 | World Journal of Gastroenterology2005，11，17： | 15 |
| 4 | Is it possible to differentiate gastric GISTs from gastric leiomyomas by EUS?显示文摘AIM: To evaluate the ultrasonog raphy (EUS) features of gastric gastrointestinal stromal tumors (GISTs) as compared with gastric leiomyomas and then to determine the EUS features that could predict malignant GISTs.METHODS: We evaluated the endoscopic EUS features in 53 patients with gastric mesenchymal tumors conf irmed by histopathologic diagnosis. The GISTs were classif ied into benign and malignant groups according to the histological risk classif ication.RESULTS: Immunohistochemical analyses demon-strated 7 leiomyomas and 46 GISTs. Inhomogenicity, hyperechogenic spots, a marginal halo and higher echogenicity as compared with the surrounding muscle layer appeared more frequently in the GISTs than in the leiomyomas (P < 0.05). The presence of at least two of these four features had a sensitivity of 89.1% and a specifi city of 85.7% for predicting GISTs. Except for tumor size and irregularity of the border, most of the EUS features were not helpful for predicting the malignant potential of GISTs. On multivariate analysis, only the maximal diameter of the GISTs was an independent predictor. The optimal size for predicting malignant GISTs was 35 mm. The sensitivity and specificity using this value were 92.3% and 78.8%, respectively.CONCLUSION: EUS may help to differentiate gastric GISTs from gastric leiomyomas. Once GISTs are suspected, surgery should be considered if the size is greater than 3.5 cm. | Gwang Ha Kim Do Youn Park Suk Kim Dae Hwan Kim Dong Heon Kim Cheol Woong Choi Jeong Heo Geun Am Song | 2009 | World Journal of Gastroenterology2009，15，27： | 12 |
| 5 | Self-expandable metallic stents for palliation of patients with malignant gastric outlet obstruction caused by stomach cancer显示文摘AIM: To ascertain clinical outcome and complications of self-expandable metal stents for endoscopic palliation of patients with malignant obstruction of the gastrointestinal (GI) tract. METHODS: A retrospective review was performed throughout August 2000 to June 2005 of 53 patients with gastric outlet obstruction caused by stomach cancer. All patients had symptomatic obstruction including nausea, vomiting, and decreased oral intake. All received self-expandable metallic stents. RESULTS: Stent implantation was successful in all 53 (100%) patients. Relief of obstructive symptoms was achieved in 43 (81.1%) patients. No immediate stent-related complications were noted. Seventeen patients had recurrent obstruction (tumor ingrowth in 14 patients, tumor overgrowth in 1 patient, and partial distal stent migration in 2 patients). The mean survival was 145 d. Median stent patency time was 187 d. CONCLUSION: Endoscopic placement of self-expandable metallic stents is a safe and effective treatment for the palliation of patients with inoperable malignant gastric outlet obstruction caused by stomach cancer. | Tae Oh Kim Dae Hwan Kang Gwang Ha Kim Jeong Heo Geun Am Song Mong Cho Dong Heon Kim Mun Sup Sim | 2007 | World Journal of Gastroenterology2007，13，6： | 11 |
| 6 | Scalable synthesis of nanoporous silicon microparticles for highly cyclable lithium-ion batteries显示文摘Nanoporous silicon is a promising anode material for high energy density batteries due to its high cycling stability and high tap density compared to other nanostructured anode materials.However,the high cost of synthesis and low yield of nanoporous silicon limit its practical application.Here,we develop a scalable,low-cost top-down process of controlled oxidation of Mg2Si in the air,followed by HCl removal of MgO to generate nanoporous silicon without the use of HF.By controlling the synthesis conditions,the oxygen content,grain size and yield of the porous silicon are simultaneously optimized from commercial standpoints.In situ environmental transmission electron microscopy reveals the reaction mechanism;the Mg2Si microparticle reacts with O2 to form MgO and Si,while preventing SiO2 formation.Owing to the low oxygen content and microscale secondary structure,the nanoporous silicon delivers a higher initial reversible capacity and initial Coulombic efficiency compared to commercial Si nanoparticles(3,033 mAh/g vs.2,418 mAh/g,84.3%vs.73.1%).Synthesis is highly scalable,and a yield of 90.4%is achieved for the porous Si nanostructure with the capability to make an excess of 10 g per batch.Our synthetic nanoporous silicon is promising for practical applications in next generation lithium-ion batteries. | Jiangyan Wang William Huang Yong Seok Kim You Kyeong Jeong Sang Cheol Kim Jeffrey Heo Hiang Kwee Lee Bofei Liu Jaehou Nah Yi Cui | 2020 | Nano Research2020，13，6： | 9 |
| 7 | Associated factors for a hyperechogenic pancreas on endoscopic ultrasound显示文摘AIM: To identify the associated risk factors for hyperechogenic pancreas (HP) which may be observed on endoscopic ultrasound (EUS) and to assess the relationship between HP and obesity. METHODS: From January 2007 to December 2007, we prospectively enrolled 524 consecutive adults who were scheduled to undergo EUS. Patients with a history of pancreatic disease or with hepatobiliary or advanced gastrointestinal cancer were excluded. Finally,284 patients were included in the analyses. We further analyzed the risk of HP according to the categories of visceral adipose tissue (VAT) and subcutaneous adipose tissue in 132 patients who underwent abdominal computed tomography scans. RESULTS: On univariate analysis, age older than 60 years, obesity (body mass index > 25 kg/m 2 ), fatty liver, diabetes mellitus, hypertension and hypercholesterolemia were identified as risk factors associated with HP (P < 0.05). On multivariate analysis, fatty liver [P = 0.008, odds ratio (OR) = 2.219], male gender (P = 0.013, OR = 2.636), age older than 60 years (P = 0.001, OR = 2.874) and hypertension (P = 0.044, OR = 2.037) were significantly associated with HP. In the subgroup analysis, VAT was a statistically significant risk factor for HP (P = 0.010, OR = 5.665, lowest quartile vs highest quartile). CONCLUSION: HP observed on EUS was associated with fatty liver, male gender, age older than 60 years, hypertension and VAT. | Cheol Woong Choi Gwang Ha Kim Dae Hwan Kang Hyung Wook Kim Dong Uk Kim Jeong Heo Geun Am Song Do Youn Park Suk Kim | 2010 | World Journal of Gastroenterology2010，16，34： | 8 |
| 8 | Controlled Ag-driven superior rate-capability of Li4Ti5O12 anodes for lithium rechargeable batteries显示文摘形态学和 Li4Ti5O12 阳极的电子结构被知道在锂决定它的电、电气化学的性质可充电的电池。Ag-Li4Ti5O12 nanofibers 讲道理地被设计了并且由一种 electrospinning 技术综合了满足要求一个维(1D ) 形态学和优异电的电导率。此处,我们发现了 1D Ag-Li4Ti5O12 nanofibers 表演与赤裸的 Li4Ti5O12 nanofibers 相比提高了特定的能力,率能力,和骑车的稳定性,由于 Ag nanoparticles (< 5 nm ) ,它主要在在 Li4Ti5O12 主要粒子之间的接口被散布。这结构的形态学由便于费用转移动力学比赤裸的 Li4Ti5O12 nanofibers 产生 20% 更高的率能力。我们的调查结果提供一个有效方法为锂改进 Li4Ti5O12 阳极的电气化学的表演可充电的电池。 | Jae-Geun Kim Dongqi Shi Min-Sik Park Goojin Jeong Yoon-Uk Heo Minsu Seo Young-Jun Kim Jung Ho Kim Shi Xue Dou | 2013 | Nano Research2013，6，5： | 7 |
| 9 | Adult intussusception caused by cystic lymphangioma of the colon:A rare case report显示文摘我们经历了结肠的 cys- tic 淋巴管瘤在为血粪的主诉进入我们的医院的 32 岁女性引起的摄取的一个盒子。在 colonoscopic 考试,有有光滑的粘膜表面的梗的膀胱的质量在下降冒号被注意。腹的 ultrasonography 和计算断层摄影术作为一个领先的点与一个多有细胞的囊性瘤揭示了左冒号摄取。突现的手术被动。在组织病理学说的考试上,膀胱的联盟者扩大了含纤维的氏族内皮细胞层和 septated 衬里的空格一是在场的。病理学的诊断是冒号的膀胱的淋巴管瘤。尽管摄取由于在一个成年人的淋巴管瘤是稀罕的,它应该它是可能的诊断的被考虑。 | Tae Oh Kim Jung Hyun Lee Gwang Ha Kim Jeong Heo Dae Hwan Kang Geun Am Song Mong Cho | 2006 | World Journal of Gastroenterology2006，12，13： | 6 |
| 10 | Sodium propionate exerts anticancer effect in mice bearing breast cancer cell xenograft by regulating JAK2/STAT3/ROS/p38 MAPK signaling显示文摘Propionate is a short-chain fatty acid(SCFA)mainly produced from carbohydrates by gut microbiota.Sodium propionate(SP)has shown to suppress the invasion in G protein-coupled receptor 41(GPR41)and GPR43-overexpressing breast cancer cells.In this study we investigated the effects of SP on the proliferation,apoptosis,autophagy,and antioxidant production of breast cancer cells.We showed that SP(5−20 mM)dose-dependently inhibited proliferation and induced apoptosis in breast cancer cell lines JIMT-1(ER-negative and HER2-expressing)and MCF7(ER-positive type),and this effect was not affected by PTX,thus not mediated by the GPR41 or GPR43 SCFA receptors.Meanwhile,we demonstrated that SP treatment increased autophagic and antioxidant activity in JIMT-1 and MCF7 breast cancer cells,which might be a compensatory mechanism to overcome SP-induced apoptosis,but were not sufficient to overcome SP-mediated suppression of proliferation and induction of apoptosis.We revealed that the anticancer effect of SP was mediated by inhibiting JAK2/STAT3 signaling which led to cell-cycle arrest at G_(0)/G_(1) phase,and increasing levels of ROS and phosphorylation of p38 MAPK which induced apoptosis.In nude mice bearing JIMT-1 and MCF7 cells xenograft,administration of SP(20 mg/mL in drinking water)significantly suppressed tumor growth by regulating STAT3 and p38 in tumor tissues.These results suggest that SP suppresses proliferation and induces apoptosis in breast cancer cells by inhibiting STAT3,increasing the ROS level and activating p38.Therefore,SP is a candidate therapeutic agent for breast cancer. | Hyun-Soo Park Joo-Hui Han Jeong Won Park Do-Hyung Lee Keun-Woo Jang Miji Lee Kyung-Sun Heo Chang-Seon Myung | 2021 | Acta Pharmacologica Sinica2021，42，8： | 4 |
| 11 | A Prospective Randomized Controlled Study Comparing Outcomes of Standard Resection and Extended Resection, Including Dissection of the Nerve Plexus and Various Lymph Nodes, in Patients With Pancreatic Head Cancer显示文摘 | Jin-Young Jang Mee Joo Kang Jin Seok Heo Seong Ho Choi Dong Wook Choi Sang Jae Park Sung-Sik Han Dong Sup Yoon Hee Chul Yu Koo Jeong Kang Sang Geol Kim Sun-Whe Kim | 2014 | Annals of Surgery2014，，4： | 2 |
| 12 | Rebampide enema therapy as a treatment for patients with chronic radiation proctitis: initial treatment or when other methods of conservative management have failed显示文摘 | Tae Oh Kim Geun Am Song Sun Mi Lee Gwang Ha Kim Jeong Heo Dae Hwan Kang Mong Cho | 2008 | International Journal of Colorectal Disease2008，，6： | 2 |
| 13 | DJ-1 mediates paraquat-induced dopaminergic neuronal cell death显示文摘 | Hyun Joo Kwon Jun Young Heo Jung Hee Shim Ji Hoon Park Kang Sik Seo Min Jeong Ryu Jeong Su Han Minho Shong Jin H. Son Gi Ryang Kweon | 2011 | Toxicology Letters2011，，： | 2 |
| 14 | Soli- tary Small Hepatic angiosarcoma: Initial and Follow-up Ima- ging findings Korean 显示文摘 | Suk Hee Heo Yong Yeon Jeong Sang Soo Shin | 2007 | Radiol2007，8，： | 1 |
| 15 | Productive high - com- plexity 3D city modeling with point clouds collected from terrestrial LiDAR 显示文摘 | Heo J Jeong S Park H | 2013 | Computers Environment & Urban Systems2013，41，9： | 1 |
| 16 | Transcriptional characterization of wnt pathway during sequential hepatic differentiation of human embryonic stem cells and adipose tissue-derived stem cells显示文摘 | Heo J Ahn EK Jeong HG | 2013 | Biochem Biophys Res Commun2013，434，2： | 1 |
| 17 | Highly valuable chemicals production from catalytic upgrading of radiata pine sawdust-derived pyrolytic vapors over mesoporous MFI zeolites显示文摘 | Park H J Heo H S Jeon J K Kim J Ryoo R Jeong K E Park Y K | | 0，，： | 1 |
| 18 | Transcriptional profiling of ESTs responsive to Rhizobium vitis from ‘Tamnara’ grapevines ( Vitis sp.)显示文摘 | Youn Jung Choi Hae Keun Yun Kyo Sun Park Jeong Ho Noh Youn Young Heo Seung Hui Kim Dae Won Kim Hee Jae Lee | 2010 | Journal of Plant Physiology2010，，13： | 1 |
| 19 | Induction of indoleamine 2,3-dioxygenase expression via heme oxygenase-1-dependant pathway during murine dendritic cell maturation显示文摘 | In Duk Jung Jun Sik Lee Chang-Min Lee Kyung Tae Noh Yeong-Il Jeong Won Sun Park Sung Hak Chun Soo Kyung Jeong Jin Wook Park Kwang Hee Son Deok Rim Heo Min-Goo Lee Yong Kyoo Shin Han Wool Kim Cheol-Heui Yun Yeong-Min Park | 2010 | Biochemical Pharmacology2010，，： | 1 |
| 20 | Imaging of Kimura's disease involving the abdomen显示文摘 | Jeong Y Y Song S K Heo S H | 2006 | AJR Am J Roentgenol2006，187，1： | 1 |
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