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| 1 | Long-term result of endoscopic Histoacryl (N-butyl-2-cyanoacrylate)injection for treatment of gastric varices显示文摘AIM:To evaluate the long-term efficacy and safety of endoscopic obliteration with Histoacryl for treatment of gastric variceal bleeding and prophylaxis.METHODS:Between January 1994 and March 2010 at SoonChunHyang University Hospital,a total of 127 patients with gastric varices received Histoacryl injections endoscopically.One hundred patients underwent endoscopic Histoacryl injections because of variceal bleeding,the other 27 patients received such injections as a prophylactic procedure.RESULTS:According to Sarin classification,56 patients were GOV1,61 patients were GOV2 and 10 patients were IGV.Most of the varices were large(F2 or F3,111 patients).The average volume of Histoacryl per each session was 1.7±1.3 cc and mean number of sessions was 1.3±0.6.(1 session-98 patients,2 sessions-25 patients,≥3 sessions-4 patients).Twenty-seven patients with high risk of bleeding(large or fundal or RCS+or Child C) received Histoacryl injection as a primary prophylactic procedure.In these patients,hepatitis B virus was the major etiology of cirrhosis,25 patients showed GOV1 or 2(92.6%)and F2 or F3 accounted for 88.9%(n=24).The rate of initial hemostasis was 98.4%and recurrent bleeding within one year occurred in 18.1%of patients.Successful hemostasis during episodes of rebleeding was achieved in 73.9%of cases.Median survival was 50 mo (95%CI 30.5-69.5).Major complications occurred in 4 patients(3.1%).The rebleeding rate in patients with hepatocellular carcinoma or GOV2 was higher than in those with other conditions.None of the 27 subjects who were treated prophylactically experienced treatment-related complications.Cumulative survival rates of the 127 patients at 6 mo,1,3,and 5 years were 92.1%,84.2%,64.2%,and 45.3%,respectively.The 6 mo cumulative survival rate of the 27 patients treated prophylactically was 75%.CONCLUSION:Histoacryl injection therapy is an effective treatment for gastric varices and also an effective prophylactic treatment of gastric varices which carry high risk of bleeding. | Eun Jung Kang Soung Won Jeong Jae Young Jang Joo Young Cho Sae Hwan Lee Hyun Gun Kim Sang Gyune Kim Young Seok Kim Young Koog Cheon Young Deok Cho Hong Soo Kim Boo Sung Kim | 2011 | World Journal of Gastroenterology2011，17，11： | 41 |
| 2 | Small sphincterotomy combined with endoscopic papillary large balloon dilation versus sphincterotomy显示文摘AIM:To compare small sphincterotomy combined with endoscopic papillary large balloon dilation(SES+ ELBD)and endoscopic sphincterotomy(EST)for large bile duct stones. METHODS:We compared prospectively SES+ELBD (group A,n=27)with conventional EST(group B, n=28)for the treatment of large bile duct stones(≥ 15 mm).When the stone could not be removed with a normal basket,mechanical lithotripsy was performed. We compared the rates of complete stone removal with one session and application of mechanical lithotripsy. RESULTS:No significant differences were observed in the mean largest stone size(A:20.8 mm,B:21.3 mm), bile duct diameter(A:21.4 mm,B:20.5 mm),number of stones(A:2.2,B:2.3),or procedure time(A:18 min, B:19 min)between the two groups.The rates of complete stone removal with one session was 85%in group A and 86%in group B(P=0.473).Mechanical lithotripsy was required for stone removal in nine of 27 patients(33%)in group A and nine of 28 patients (32%,P=0.527)in group B.CONCLUSION:SES+ELBD did not show significant benefits compared to conventional EST,especially for the removal of large(≥15 mm)bile duct stones. | Hyun Gun Kim Young Koog Cheon Young Deok Cho Jong Ho Moon Do Hyun Park Tae Hoon Lee Hyun Jong Choi Sang-Heum Park Joon Seong Lee Moon Sung Lee | 2009 | World Journal of Gastroenterology2009，15，34： | 34 |
| 3 | Electroacupuncture on PC6 Prevents Opioid-Induced Nausea and Vomiting after Laparoscopic Surgery显示文摘Objective:To investigate the treatment time dependence of electroacupuncture(EA) on Neiguan (PC6) for preventing postoperative nausea and vomiting(PONV).Methods:One hundred and seventy-eight patients,who had received intravenous patient-controlled analgesia(PCA) with Fentanyl,were assigned randomly to three groups using random numbers:a pre-operative EA group(PrEA),a post-operative EA group(PoEA),and a non-acupuncture control group(NC).An anesthetist evaluated the incidence and severity of nausea and vomiting for 48 h after surgery blindly.The main outcomes were severity and freguency of PONV,which were measured with a self-reported questionnaire and a confirmation from the anesthetist.The data were analyzed with ANOVA and Z-test.Results:The incidence of nausea and vomiting was significantly lower in the PrEA group than the NC group during 48 h after surgery(P<0.01,P<0.05).The incidence of vomiting was also significantly lower in the PrEA group than the PoEA group(P<0.05).The PoEA subjects evidenced no significant differences compared with the NC subjects in terms of the incidence of nausea and vomiting(P<0.05).The severity of nausea was significantly lower in the PrEA group than in the NC and PoEA groups(P<0.05).Conclusions:EA on PC6 is effective in the prevention of PONV,and pre-operative acupuncture is more effective than post-operative acupuncture. | Siwoo Lee Myeong Soo Lee Deok Hwa Choi Su Kyung Lee | 2013 | Chinese Journal of Integrative Medicine2013，19，4： | 32 |
| 4 | Photodynamic therapy prolongs metal stent patency in patients with unresectable hilar cholangiocarcinoma显示文摘AIM:To evaluate the effect of photodynamic therapy (PDT) on metal stent patency in patients with unresectable hilar cholangiocarcinoma (CC). METHODS:This was a retrospective analysis of patients with hilar CC referred to our institution from December, 1999 to January, 2011. Out of 232 patients, thirty-three patients with unresectable hilar CC were treated. Eighteen patients in the PDT group were treated with uncovered metal stents after one session of PDT. Fifteen patients in the control group were treated with metal stents alone. Porfimer sodium (2 mg/kg) was administered intravenously to PDT patients. Fortyeight hours later, PDT was administered using a diffusing fiber that was advanced across the tumor by either endoscopic retrograde cholangiopancreatography or percutaneous cholangiography. After performance of PDT, uncovered metal stents were inserted to ensure adequate decompression and bile drainage. Patient survival rates and cumulative stent patency were calculated using Kaplan-Meier analysis with the log-rank test. RESULTS:The PDT and control patients were comparable with respect to age, gender, health status, pretreatment bilirubin, and hilar CC stage. When compared to control, the PDT group was associated with significantly prolonged stent patency (median 244 ± 66 and 177 ± 45 d, respectively, P = 0.002) and longer patient survival (median 356 ± 213 and 230 ± 73 d, respectively, P = 0.006). Early complication rates were similar between the groups (PDT group 17%, control group 13%) and all patients were treated conservatively. Stent malfunctions occurred in 14 PDT patients (78%) and 12 control patients (80%). Of these 26 patients, twenty-two were treated endoscopically and four were treated with external drainage. CONCLUSION:Metal stenting after one session of PDT may be safe with acceptable complication rates. The PDT group was associated with a significantly longer stent patency than the control group in patients with unresectable hilar CC. | Tae Yoon Lee Young Koog Cheon Chan Sup Shim Young Deok Cho | 2012 | World Journal of Gastroenterology2012，18，39： | 28 |
| 5 | Double guidewire technique vs transpancreatic precut sphincterotomy in difficult biliary cannulation显示文摘AIM:To compare the outcomes between doubleguidewire technique(DGT) and transpancreatic precut sphincterotomy(TPS) in patients with difficult biliary cannulation.METHODS:This was a prospective,randomized study conducted in single tertiary referral hospital in Korea.Between January 2005 and September 2010.A total of 71 patients,who bile duct cannulation was not possible and selective pancreatic duct cannulation was achieved,were randomized into DGT(n = 34) and TPS(n = 37) groups.DGT or TPS was done for selective biliary cannulation.We measured the technical success rates of biliary cannulation,median cannulation time,and procedure related complications.RESULTS:The distribution of patients after randomization was balanced,and both groups were comparable in baseline characteristics,except the higher percentage of endoscopic nasobiliary drainage in the DGT group(55.9% vs 13.5%,P < 0.001).Successful cannulation rate and mean cannulation times in DGT and TPS groups were 91.2% vs 91.9% and 14.1 ± 13.2 min vs 15.4 ± 17.9 min,P = 0.732,respectively.There was no significant difference between the two groups.The overall incidence of post-endoscopic retrograde cholangiopancreatography(ERCP) pancreatitis was 38.2% vs 10.8%,P < 0.011 in the DGT group and the TPS group;post-procedure pancreatitis was significantly higher in the DGT group.But the overall incidence of post-ERCP hyperamylasemia was no significant difference between the two groups;DGT group vs TPS group:14.7% vs 16.2%,P < 1.0.CONCLUSION:When free bile duct cannulation was difficult and selective pancreatic duct cannulation was achieved,DGT and TPS facilitated biliary cannulation and showed similar success rates.However,post-procedure pancreatitis was significantly higher in the DGT group. | Young Wook Yoo Sang-Woo Cha Woong Cheul Lee Sae Hee Kim Anna Kim Young Deok Cho | 2013 | World Journal of Gastroenterology2013，19，1： | 25 |
| 6 | Comparative study of chitosan/fibroin–hydroxyapatite and collagen membranes for guided bone regeneration in rat calvarial defects: micro-computed tomography analysis显示文摘This study aimed to utilize micro-computed tomography(micro-CT)analysis to compare new bone formation in rat calvarial defects using chitosan/fibroin–hydroxyapatite(CFB–HAP)or collagen(Bio-Gide)membranes.Fifty-four(54)rats were studied.A circular bony defect(8 mm diameter)was formed in the centre of the calvaria using a trephine bur.The CFB–HAP membrane was prepared by thermally induced phase separation.In the experimental group(n518),the CFB–HAP membrane was used to cover the bony defect,and in the control group(n518),a resorbable collagen membrane(Bio-Gide)was used.In the negative control group(n518),no membrane was used.In each group,six animals were euthanized at 2,4 and 8 weeks after surgery.The specimens were then analysed using micro-CT.There were significant differences in bone volume(BV)and bone mineral density(BMD)(P,0.05)between the negative control group and the membrane groups.However,there were no significant differences between the CFB–HAP group and the collagen group.We concluded that the CFB–HAP membrane has significant potential as a guided bone regeneration(GBR)membrane. | Jae Min Song Sang Hun Shin Yong Deok Kim Jae Yeol Lee Young Jae Baek Sang Yong Yoon Hong Sung Kim | 2014 | International Journal of Oral Science2014，6，2： | 15 |
| 7 | Endoscopic ultrasonography does not differentiate neoplastic from non-neoplastic small gallbladder polyps显示文摘AIM:To assess the ability of endoscopic ultrasonography(EUS) to differentiate neoplastic from non-neoplastic polypoid lesions of the gallbladder(PLGs) .METHODS:The uses of EUS and transabdominal ultrasonography(US) were retrospectively analyzed in 94 surgical cases of gallbladder polyps less than 20 mm in diameter.RESULTS:The prevalence of neoplastic lesions with a diameter of 5-10 mm was 17.2%(10/58) ;11-15 mm,15.4%(4/26) ,and 16-20 mm,50%(5/10) .The overall diagnostic accuracies of EUS and US for small PLGs were 80.9% and 63.9%(P < 0.05) ,respectively.EUS correctly distinguished 12(63.2%) of 19 neoplastic PLGs but was less accurate for polyps less than 1.0 cm(4/10,40%) than for polyps greater than 1.0 cm(8/9,88.9%) (P = 0.02) .CONCLUSION:Although EUS was more accurate than US,its accuracy for differentiating neoplastic from non-neoplastic PLGs less than 1.0 cm was low.Thus,EUS alone is not suffi cient for determining a treatment strategy for PLGs of less than 1.0 cm. | Young Koog Cheon Won Young Cho Tae Hee Lee Young Deok Cho Jong Ho Moon Joon Seong Lee Chan Sup Shim | 2009 | World Journal of Gastroenterology2009，15，19： | 12 |
| 8 | Diagnostic value for extrahepatic metastases of hepatocellular carcinoma in positron emission tomography/computed tomography scan显示文摘AIM: To evaluated the value of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) scan in diagnosis of hepatocellular carcinoma (HCC) and extrahepatic metastases. METHODS: A total of 138 patients with HCC who had both conventional imaging modalities and 18F-FDG PET/CT scan done between November 2006 and March 2011 were enrolled. Diagnostic value of each imaging modality for detection of extrahepatic metastases was evaluated. Clinical factors and tumor characteristics including PET imaging were analyzed as indicative factors for metastases by univariate and multivariate methods. RESULTS: The accuracy of chest CT was significantly superior compared with the accuracy of PET imaging for detecting lung metastases. The detection rate of metastatic pulmonary nodule ≥ 1 cm was 12/13 (92.3%), when < 1 cm was 2/10 (20%) in PET imaging. The accuracy of PET imaging was significantly superior compared with the accuracy of bone scan for detecting bone metastases. In multivariate analy- sis, increased tumor size (≥ 5 cm) (P = 0.042) and increased average standardized uptake value (SUV) uptake (P = 0.028) were predictive factors for extrahepatic metastases. Isometabolic HCC in PET imaging was inversely correlated in multivariate analysis (P = 0.035). According to the receiver operating characteristic curve, the optimal cutoff of average SUV to predict extrahepatic metastases was 3.4. CONCLUSION: 18F-FDG PET/CT scan is invaluable for detection of lung metastases larger than 1 cm and bone metastases. Primary HCC having larger than 5 cm and increased average SUV uptake more than 3.4 should be considered for extrahepatic metastases. | Ji Eun Lee Jae Young Jang Soung Won Jeong Sae Hwan Lee Sang Gyune Kim Sang-Woo Cha Young Seok Kim Young Deok Cho Hong Soo Kim Boo Sung Kim So Young Jin Deuk Lin Choi | 2012 | World Journal of Gastroenterology2012，18，23： | 10 |
| 9 | Endocrine Regulation of Energy Metabolism by the Skeleton显示文摘 | Na Kyung Lee Hideaki Sowa Eiichi Hinoi Mathieu Ferron Jong Deok Ahn Cyrille Confavreux Romain Dacquin Patrick J. Mee Marc D. McKee Dae Young Jung Zhiyou Zhang Jason K. Kim Franck Mauvais-Jarvis Patricia Ducy Gerard Karsenty | 2007 | Cell2007，，3： | 5 |
| 10 | Long-term treatment issues with chromite ore processing residue (COPR): Cr 6+ reduction and heave显示文摘 | Deok Hyun Moon Mahmoud Wazne Dimitris Dermatas Christos Christodoulatos Adriana M. Sanchez Dennis G. Grubb Maria Chrysochoou Min Gyu Kim | 2007 | Journal of Hazardous Materials2007，，3： | 2 |
| 11 | Risk Factors for Progression from Cytomegalovirus Viremia to Cytomegalovirus Disease after Allogeneic Hematopoietic Stem Cell Transplantation显示文摘 | Ji Eun Jang Shin Young Hyun Yun Deok Kim Sul Hee Yoon Doh Yu Hwang Soo Jeong Kim Yuri Kim Jin Seok Kim June-Won Cheong Yoo Hong Min | 2012 | Biology of Blood and Marrow Transplantation2012，，6： | 2 |
| 12 | Presumptive case of sparganosis manifesting as a hepatic mass: A case report and literature review显示文摘A 60-year-old man was admitted due to rectosigmoid colon cancer, and a hepatic mass was incidentally found during the staging work-up. The mass appeared cystic with a thick wall and contained multiple bizarre cord-like structures on ultrasound, computed tomography and magnetic resonance imaging. The differential diagnoses included organizing abscess/hematoma, foreign body granuloma and parasite infestation. Serologic study revealed anti-sparganum antibodies. Over 4-year followup, the patient did not complain of symptoms, and no changes in the characteristics of the liver mass were observed. Hepatic sparganosis is rare; only two cases have been clinically reported, and no detailed radiologic description was available until now. This case report presents a detailed radiologic description of a hepatic mass that could most likely represent hepatic sparganosis. | Gyeong Deok Jo Jae Young Lee Sung-Tae Hong Jung Hoon Kim Joon Koo Han | 2016 | World Journal of Radiology2016，8，10： | 2 |
| 13 | Assessment of calcium polysulfide for the remediation of hexavalent chromium in chromite ore processing residue (COPR)显示文摘 | Mahmoud Wazne Santhi Chandra Jagupilla Deok Hyun Moon Sarath Chandra Jagupilla Christos Christodoulatos Min Gyu Kim | 2007 | Journal of Hazardous Materials2007，，3： | 2 |
| 14 | Evaluation of long-term results and recurrent factors after operative and nonoperative treatment for hepatolithiasis显示文摘 | Young Koog Cheon Young Deok Cho Jong Ho Moon Joon Seong Lee Chan Sup Shim | 2009 | Surgery2009，，5： | 2 |
| 15 | Intraductal balloon-guided direct peroral cholangioscopy with an ultraslim upper endoscope (with videos)显示文摘 | Jong Ho Moon Bong Min Ko Hyun Jong Choi Su Jin Hong Young Koog Cheon Young Deok Cho Joon Seong Lee Moon Sung Lee Chan Sup Shim | 2009 | Gastrointestinal Endoscopy2009，，2： | 2 |
| 16 | Overtube-balloon–assisted direct peroral cholangioscopy by using an ultra-slim upper endoscope (with videos)显示文摘 | Hyun Jong Choi Jong Ho Moon Bong Min Ko Su Jin Hong Hyun Cheol Koo Young Koog Cheon Young Deok Cho Joon Seong Lee Moon Sung Lee Chan Sup Shim | 2009 | Gastrointestinal Endoscopy2009，，4： | 2 |
| 17 | Laparoendoscopic Single-site Surgery in Urology: Worldwide Multi-institutional Analysis of 1076 Cases显示文摘 | Jihad H. Kaouk Riccardo Autorino Fernando J. Kim Deok Hyun Han Seung Wook Lee Sun Yinghao Jeffrey A. Cadeddu Ithaar H. Derweesh Lee Richstone Luca Cindolo Anibal Branco Francesco Greco Mohamad Allaf René Sotelo Evangelos Liatsikos Jens-Uwe Stolzenburg Abh | 2011 | European Urology2011，，5： | 2 |
| 18 | Comparison of Endoscopic Papillary Balloon Dilation and Sphincterotomy in Young Patients with CBD Stones and Gallstones显示文摘 | Yu Ri Seo Jong Ho Moon Hyun Jong Choi Dong Choon Kim Ji Su Ha Tae Hoon Lee Sang-Woo Cha Young Deok Cho Sang-Heum Park Sun-Joo Kim | 2014 | Digestive Diseases and Sciences2014，，5： | 2 |
| 19 | Papillary balloon dilation is not itself a cause of post‐endoscopic retrograde cholangiopancreatography pancreatitis; results of anterograde and retrograde papillary balloon dilation显示文摘 | Yu Ri Seo Jong Ho Moon Hyun Jong Choi Dong Choon Kim Tae Hoon Lee Sang‐Woo Cha Young Deok Cho Sang‐Heum Park Sun‐Joo Kim | 2013 | J Gastroenterol Hepatol2013，，8： | 2 |
| 20 | Immobilization mechanisms of Pb in firing range soils using Apatite II phosphate显示文摘 | Dermatas Dimitris Grubb Dennis G Moon Deok Hyun | 2006 | Chinese Journal Of Geochemistry2006，25，B08： | 2 |
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