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| 1 | 自发性脑出血治疗指南美国心脏协会/美国卒中协会对医疗卫生专业人员发布的指南显示文摘目的本指南旨在为急性自发性脑出血的诊断和治疗提供最新的综合性推荐意见。方法通过Medline进行规范的文献检索,利用证据表合并资料。撰写委员会成员通过远程电信会议讨论根据资料得出的推荐意见。采用美国心脏协会卒中委员会的证据分级方案对推荐意见进行分级。由6位同行评议专家以及卒中委员会科学声明监督委员会和卒中委员会领导委员会成员对指南的草案进行发表前审阅。预期本指南在3年内完全更新。结果本文为脑出血患者的医疗诊治提供了循证指南。重点包括诊断、止血、血压管理、院内管理和护理、预防内科合并症、外科治疗、转归预测、康复、预防复发以及将来需要考虑的问题。结论脑出血是一种严重的疾病,早期积极救治可影响其转归。本指南为脑出血患者的目标导向治疗提供了一个框架。 | Lewis B. Morgenstem J. Claude Hemphill Ⅲ Craig Anderson Kyra Becker Joseph P. Broderick E. Sander Connolly Jr Steven M. Greenberg James N. Huang R. Loch Macdonald Steven R. Messe Pamela H. Mitchell Magdy Selim Rafael J. Tamargo 王玉洁(译) 王健(译) 刘相玉(译) 谢丽丽(译) | 2010 | 国际脑血管病杂志2010,,8: | 259 |
| 2 | Updated Analysis of SWOG-Directed Intergroup Study 0116: A Phase III Trial of Adjuvant Radiochemotherapy Versus Observation After Curative Gastric Cancer Resection显示文摘 | Stephen R. Smalley Jacqueline K. Benedetti Daniel G. Haller Scott A. Hundahl Norman C. Estes Jaffer A. Ajani Leonard L. Gunderson Bryan Goldman James A. Martenson J. Milburn Jessup Grant N. Stemmermann Charles D. Blanke John S. Macdonald | 2012 | Journal of Clinical Oncology2012,,19: | 13 |
| 3 | Guidelines for the Management of Spontaneous Intracerebral Hemorrhage: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association显示文摘 | Lewis B. Morgenstern J. Claude Hemphill Craig Anderson Kyra Becker Joseph P. Broderick E. Sander Connolly Steven M. Greenberg James N. Huang R. Loch Macdonald Steven R. Messé Pamela H. Mitchell Magdy Selim Rafael J. Tamargo | 2010 | Stroke2010,,9: | 10 |
| 4 | 青少年运动缺乏症(EDD)研究的10大问题显示文摘运动缺乏症(EDD)是一种儿科疾病,特点是中高强度体力活动(MVPA)下降,低于目前的推荐量,也与积极的健康结果不一致。目前,大多数儿童和青少年符合EDD的诊断标准,因为他们没有达到日常MVPA的最低要求。本文的目的是强调10个与青少年EDD有关的重要研究问题。需要进行重要的研究来更好地定义EDD的临床表现,包括评估体力活动行为以确定开始出现EDD的年龄或发育阶段;包括运动技巧和体能的运动起源(kinesiogenesis)的检测;以及对影响青少年MVPA的生活方式因素的评估。关于治疗EDD的干预措施和政策的研究问题,包括评估对卫生保健从业者进行运动医学重要性的教育和训练;确定在临床上识别和治疗EDD青少年的方法的有效性;开发敏感的、特效的、经济的方法以诊断青少年EDD;以及定制方法以促进本病诊疗的医疗保险赔付。如果未来研究不能优化EDD青少年的识别、治疗和管理方案,具有重大影响的生物医学、心理、经济和政治的新的卫生保健问题将会不断出现。 | Avery D. Faigenbam Thomas M. Best James MacDonald Gregory D. Myer Andrea Stracciolini | 2015 | 北京体育大学学报2015,38,11: | 8 |
| 5 | The current status of nitrogen fertiliser use efficiency and future research directions for the Australian cotton industry显示文摘Fifty years of sustained investment in research and development has left the Australian cotton industry well placed to manage nitrogen(N) fertiliser. The average production in the Australian cotton industry today is greater than two tonnes of lint per hectare due to improved plant genetics and crop management. However, this average yield is well below the yield that would be expected from the amount of N fertiliser used. It is clear from the recent studies that across all growing regions, conversion of fertiliser N into lint is not uniformly occurring at application rates greater than 200-240 kg·hm^(-2) of N. This indicates that factors other than N availability are limiting yield, and that the observed nitrogen fertiliser use efficiency(NFUE) values may be caused by subsoil constraints such as sodicity and compaction. There is a need to investigate the impact of subsoil constraints on yield and NFUE.Gains in NFUE will be made through improved N fertiliser application timing, better targeting the amount of fertiliser applied for the expected yield, and improved soil N management. There is also a need to improve the ability and confidence of growers to estimate the contribution of soil N mineralisation to the crop N budget. Many Australian studies including data that could theoretically be collated in a meta-analysis suggest relative NFUE values as a function of irrigation technique; however, with the extensive list of uncontrolled variables and few studies using non-furrow irrigation, this would be a poor substitute for a single field-based study directly measuring their efficacies. In irrigated cotton, a re-examination of optimal NFUE is due because of the availability of new varieties and the potential management and long-term soil resilience implications of the continued removal of mineralised soil N suggested by high NFUE values. NFUE critical limits still need to be derived for dryland systems. | MACDONALD Ben C.T. LATIMER James O. SCHWENKE Graeme D. NACHIMUTHU Gunasekhar BAIRD Jonathan C. | 2018 | Journal of Cotton Research2018,1,3: | 5 |
| 6 | Comparison of cytokine and phosphoprotein profiles in idiopathic and Crohn’s disease-related perianal fistula显示文摘BACKGROUND Perianal fistulae are either primary(idiopathic)or secondary[commonly associated with Crohn’s disease,(CD)].It is assumed,although not proven,that the pathophysiology differs.AIM To systematically compare the clinical phenotypes,cytokine and phosphoprotein profiles of idiopathic and CD-related perianal fistulae.METHODS Sixty-one patients undergoing surgery for perianal fistula were prospectively recruited(48 idiopathic,13 CD)into a cohort study.Clinical data,including the Perineal Disease Activity Index(PDAI)and EQ-5D-5L were collected.Biopsies of the fistula tract,granulation tissue,internal opening mucosa and rectal mucosa were obtained at surgery.Concentrations of 30 cytokines and 39 phosphoproteins were measured in each biopsy using a magnetic bead multiplexing instrument and a chemiluminescent antibody array respectively.Over 12000 clinical and 23500 laboratory measurements were made.RESULTS The PDAI was significantly higher(indicating more active disease)in the CD group with a mean difference of 2.40(95%CI:0.52-4.28,P=0.01).Complex pathoanatomy was more prevalent in the CD group,namely more multiple fistulae,supralevator extensions,collections and rectal thickening.The IL-12p70 concentration at the internal opening specimen site was significantly higher(median difference 19.7 pg/mL,99%CI:0.2-40.4,P=0.008)and the IL-1RA/IL-1βratio was significantly lower in the CD group at the internal opening specimen site(median difference 15.0,99%CI=0.4-50.5,P=0.008).However in the remaining 27 cytokines and all 39 of the phosphoproteins across the four biopsy sites,no significant differences were found between the groups.CONCLUSION CD-related perianal fistulae are more clinically severe and anatomically complex than idiopathic perianal fistulae.However,overall there are no major differences in cytokine and phosphoprotein profiles. | James B Haddow Omar Musbahi Thomas T MacDonald Charles H Knowles | 2019 | World Journal of Gastrointestinal Pathophysiology2019,10,4: | 2 |
| 7 | 高分辨率能谱测井——识别复杂矿物(二)显示文摘中子诱发俘获能谱测井仪能够测量井下岩石中特定元素的含量。岩石物理师可根据这些测量数据得出矿物、岩性和地层骨架等性质。早期能谱测井仪的能谱灵敏度不足以获取总有机碳数据,而总有机碳是认识非常规资源远景区的重要测量数据。一种新的测井仪器可提供总碳测量,据此可确定有机碳含量。该仪器在识别复杂岩性方面有着前所未有的精度。 | Manuel Aboud Rob Badry Jim Grau Susan Herron FaridHamichi Jack Horkowitz James Hemingway Robin MacDonald Pablo Saldungaray Don Stachiw Northern Cross Christian Stoller Princeston Junction Richard E.Williams | 2015 | 国外测井技术2015,0,1: | 2 |
| 8 | Isoflurane Regulates Atypical Type-A γ-Aminobutyric Acid Receptors in Alveolar Type II Epithelial Cells显示文摘 | Yun-Yan Xiang Xuanmao Chen Jingxin Li Shuanglian Wang Gil Faclier John F. MacDonald James C. Hogg Beverley A. Orser Wei-Yang Lu | 2013 | Anesthesiology2013,,5: | 1 |
| 9 | A method for assessment of the freeze-thaw resistance of preformed foam cellular concrete显示文摘 | PAUL J Tikalsky JAMES Pospisil WILLIAM MacDonald | 2004 | Cement and Concrete Research2004,34,5: | 1 |
| 10 | Recombinase polymerase amplification:Emergence as a critical molecular technology for rapid, low-resource diagnostics显示文摘 | James A Macdonald J | 2015 | Expert Rev Mol Diagn2015,,11: | 1 |
| 11 | The effect of atmospheric conditions on the swing of a cricket ball 显示文摘 | JAMES D MACDONALD D C HART J | 2012 | Procedia Engineering2012,34,: | 1 |
| 12 | A phase II study of farnesyl transferase inhibitor R115777 in pancreatic cancer: A Southwest oncology group (SWOG 9924) study显示文摘 | John S. Macdonald Sheryl McCoy Robert P. Whitehead Syma Iqbal James L. Wade Jeffrey K. Giguere James L. Abbruzzese | 2005 | Investigational New Drugs2005,,5: | 1 |
| 13 | Analysis of Anal Droplets of the Western Flower Thrips Frankliniella occidentalis显示文摘 | Kenneth M. MacDonald James G. C. Hamilton Robert Jacobson William D. J. Kirk | 2003 | Journal of Chemical Ecology2003,,10: | 1 |
| 14 | Gemcitabine and Cisplatin for Patients with Metastatic or Recurrent Esophageal Carcinoma: A Southwest Oncology Group Study显示文摘 | Susan G. Urba Kari Chansky Peter J. vanVeldhuizen Robert E. Pluenneke Jacqueline K. Benedetti John S. Macdonald James L. Abbruzzese | 2004 | Investigational New Drugs2004,,1: | 1 |
| 15 | Modeling the Cost of Food Safety Regulation显示文摘 | STEPHAN CRUTCHFIELD | 1996 | American Journal of Agricultural Economics1996,78,4: | 1 |
| 16 | Highly Efficient Organic Light‐Emitting Diode Based on a Hidden Thermally Activated Delayed Fluorescence Channel in a Heptazine Derivative显示文摘 | Jie Li Tetsuya Nakagawa James MacDonald Qisheng Zhang Hiroko Nomura Hiroshi Miyazaki Chihaya Adachi | 2013 | Adv Mater2013,,24: | 1 |
| 17 | Updated Analysis of SWOG-Directed Intergroup Study 0116: A Phase III Trial of Adjuvant Radiochemotherapy Versus Observation After Curative Gastric Cancer Resection显示文摘 | Stephen R. Smalley Jacqueline K. Benedetti Daniel G. Haller Scott A. Hundahl Norman C. Estes Jaffer A. Ajani Leonard L. Gunderson Bryan Goldman James A. Martenson J. Milburn Jessup Grant N. Stemmermann Charles D. Blanke John S. Macdonald | 2012 | Journal of Clinical Oncology2012,,19: | 1 |
| 18 | Suppression of mouse hepatocyte apoptosis by peroxisome proliferators: role of PPARalpha and TNFalpha显示文摘 | Hasmall SC James NH Macdonald N Gonzalez FJ Peters JM Roberts RA | 2000 | Mutat Res2000,448,2: | 1 |
| 19 | Apoptosis and proliferation in nongenotoxic carcinogenesis: species differences and role of PPARalpha显示文摘 | Roberts RA James NH Hasmall SC Holden PR Lambe K Macdonald N | 2000 | Toxicol Lett2000,,: | 1 |
| 20 | Amyloid Formation by Mutant Huntingtin: Threshold, Progressivity and Recruitment of Normal Polyglutamine Proteins显示文摘 | C. Chris Huang Peter W. Faber Francesca Persichetti Vivek Mittal Jean-Paul Vonsattel Marcy E. MacDonald James F. Gusella | 1998 | Somatic Cell and Molecular Genetics1998,,4: | 1 |