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| 1 | Role of quorum sensing in bacterial infections显示文摘Quorum sensing(QS) is cell communication that is widely used by bacterial pathogens to coordinate the expression of several collective traits, including the production of multiple virulence factors, biofilm formation, and swarming motility once a population threshold is reached. Several lines of evidence indicate that QS enhances virulence of bacterial pathogens in animal models as well as in human infections; however, its relative importance for bacterial pathogenesis is still incomplete. In this review, we discuss the present evidence from in vitro and in vivo experiments in animal models, as well as from clinical studies, that link QS systems with human infections. We focus on two major QS bacterial models, the opportunistic Gram negative bacteria Pseudomonas aeruginosa and the Gram positive Staphylococcus aureus, which are also two of the main agents responsible of nosocomial and wound infections. In addition, QS communication systems in other bacterial, eukaryotic pathogens, and even immune and cancer cells are also reviewed, and finally, the new approaches proposed to combat bacterial infections by the attenuation of their QS communication systems and virulence are also discussed. | Israel Castillo-Juárez Toshinari Maeda Edna Ayerim Mandujano-Tinoco María Tomás Berenice Pérez-Eretza Silvia Julieta García-Contreras Thomas K Wood Rodolfo García-Contreras | 2015 | World Journal of Clinical Cases2015，3，7： | 15 |
| 2 | Development of an Arabic version of the National Eye Institute Visual Function Questionnaire as a tool to study eye diseases patients in Egypt显示文摘AIM:To develop and test an Arabic version of the National Eye Institute Visual Function Questionnaire-25(NEI-VFQ-25).METHODS:NEI-VFQ-25 was translated into Arabic according to WHO translation guidelines. We enrolled adult consenting patients with bilateral chronic eye diseases who presented to 14 hospitals across Egypt from October to December 2012, and documented their clinical findings. Psychometric properties were then tested using STATA.RESULTS:We recruited 379 patients, whose mean age was(54.5±15)y. Of 46.2% were males, 227 had cataract,31 had glaucoma, 23 had retinal detachment, 37 had diabetic retinopathy, and 61 had miscellaneous visual defects. Non-response rate and the floor and ceiling numbers of the Arabic version(ARB-VFQ-25) were calculated. Internal consistency was high in all subscales(except general health), with Cronbach-α ranging from0.702-0.911. Test-retest reliability was high(intraclass correlation coefficient 0.79).CONCLUSION:RB-VFQ-25 isareliableandvalidtool for assessing visual functions of Arabic speaking patients. However, some questions had high non-response rates and should be substituted by available alternatives. Our results support the importance of including self-reported visual functions as part of routine ophthalmologic examination. | Nizar Saleh Abdelfattah Mohamed Amgad Ahmed A Salama Marina E Israel Ghada A Elhawary Ahmed E Radwan Mohamed M Elgayar Tamer M EL Nakhal Islam T Elkhateb Heba A Hashem Doha K Embaby Amira A Elabd Reem K Elwy Magdi S Yacoub Hamdy Salem Mohamed Abdel-Baqy Ahmad Kassem | 2014 | International Journal of Ophthalmology(English edition)2014，7，5： | 8 |
| 3 | Heritability of children's proso- cial behavior and differential susceptibility to parenting by vari- ation in the dopamine receptor D4 gene 显示文摘 | Knafo A Israel S Ebstein RP | 2011 | Dev Psychopathol2011，23，1： | 1 |
| 4 | Individual differences in allocation of funds in the dictator game associated with length of the arginine vasopressin 1areceptor RS3promoter region and correlation between RS3length and hippocampal mRNA显示文摘 | Knafo A Israel S Darvasi A | 2008 | Genes Brain Behav2008，7，3： | 1 |
| 5 | Do the pelvic lymph nodes predict the parametrial status in cervical cancer stages I B-- II A? 显示文摘 | Puente R Guzman S Israel E | 2004 | Int J Gynecol Cancer2004，14，： | 1 |
| 6 | Extracellular polysaccha- rides production by Arthrobacter viscosus显示文摘 | Elena L Israel R Anzeles S M | 2003 | Journal of Food Engineering2003，60，： | 1 |
| 7 | The integrated model:implications for worksite health promotion and occupational health and safety practice显示文摘 | Baker E Israel BA Schurman S | 1996 | Health Educ Q1996，23，2： | 1 |
| 8 | Leptin receptor modulation of adiposity and fertility显示文摘 | Israel D Chua S Jr | 2010 | Trends Endocrinol Metab2010，21，1： | 1 |
| 9 | Extracellular polysaccharides production by A rthrobacter viscosus显示文摘 | Elena L Israel R Anzeles S M | 2003 | Journal of Food Engineering2003，60，： | 1 |
| 10 | Characteristics of insomnia in the Unit- ed States: results of the 1991 National Foundation Survey I显示文摘 | Ancoli - Israel S Roth T | 1999 | Sleep1999，22，2： | 1 |
| 11 | Electrical storm in patients with an implanted defibrillator: a matter of definition显示文摘 | ISRAEL C W BAROLD S S | 2007 | Ann Noninvasive Electrocardiol2007，12，： | 1 |
| 12 | Sleep disordered breathing in community-dwelling elderly显示文摘 | Ancoli- Israel S Kripke DF Klauber MR | 1991 | Sleep1991，14，6： | 1 |
| 13 | Invasive Shigella flexneri activates NF-KB through a lipopolysaccharide-dependent innate intracellular response and leads to IL-8 expression in epithelial cells显示文摘 | Phipott DJ Yamaok S Israel A | 2000 | J Immunol2000，165，： | 1 |
| 14 | Bone morphogenetic protein-2 causes commitmem and differentiation in C3H10T1/2 and 3T3 cells显示文摘 | Wang EA Israel DI Kelly S | 1993 | Growth Factors1993，9，： | 1 |
| 15 | Oxidative stress induces autophagic cell death inde- pendent of apoptosis in transformed and cancer cells 显示文摘 | Chen Y McMillan-Ward E Kong J Israels S J Gibson SB | 2008 | Cell Death Differ2008，15，1： | 1 |
| 16 | ECG to Identify Individuals显示文摘 | Israel S A lrvine J M Cheng A | 2005 | Pattern Recognition2005，38，1： | 1 |
| 17 | PET/CT for atherosclerotic plaque imaging 显示文摘 | Ben-Haim S Israel O | 2006 | QJ Nuel Ned Mol Imaging2006，50，： | 1 |
| 18 | PET/CT for atherosclerotic plaque imaging 显示文摘 | Ben-Haim S Israel O | 2006 | Q J Nucl Med Mol Imaging2006，50，1： | 1 |
| 19 | Individual differences in allocation of funds in the dictator game associated with length of the arginine vasopressin 1areceptor RS3promoter region and correlation between RS3length and hippocampal mRNA显示文摘 | Knafo A Israel S Darvasi A | 2008 | GenesBrain Behav2008，7，3： | 1 |
| 20 | Successful Treatment of Severe Gastrointestinal Bleeding Secondary to Crohn Disease with Recombinant Factor VIIa显示文摘 | Eva Girona Joaquín Borrás-Blasco Venancio Conesa-García Andrés Navarro-Ruiz Javier Solís Mariana Fe García-Sepulcre Israel Oliver-García | 2007 | Southern Medical Journal2007，，6： | 1 |
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