|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Organic Field-effect Transistors Based on Tetrathiafulvalene Derivatives显示文摘1 Restults Tetrathiafulvalene (TTF) and its derivatives have been extensively investigated in the field of organic conductors and superconductors since 1973. Recently, their application in organic field-effect transistors (OFETs) has attracted considerable attention. So far, on the one hand, the fabrication techniques of the TTF-based FETs have been primarily limited to high vacuum evaporation, which is a relatively expensive process. On the other hand, low FET performances, such as the low on/off ratio... | Yunqi Liu, Xike Gao, Ying Wang, Wenfeng Qiu, Weiping Wu, Hengjun Zhang, Gui Yu, Daoben Zhu(Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China) | 2007 | 复旦学报(自然科学版)2007，46，5： | 1 |
| 2 | Arsenite induces HIF-1α and VEGF through PI3K, Akt and reactive oxygen species in DU145 human prostate carcinoma cells显示文摘 | Ning Gao Liqin Shen Zhuo Zhang Stephen S. Leonard Hengjun He Xue-Guang Zhang Xianglin Shi Bing-Hua Jiang | 2004 | Molecular and Cellular Biochemistry (-)2004，，1： | 1 |
| 3 | Identification and impact of hepatitis B virus DNA and antigens in pancreatic cancer tissues and adjacent non-cancerous tissues显示文摘 | Yan Jin Hengjun Gao Hao Chen Jian Wang Min Chen Guohua Li Liwei Wang Jianren Gu Hong Tu | 2013 | Cancer Letters2013，，2： | 1 |
| 4 | Oligomicroarray-based primary study of gene expression profile changes in Barrett’s esophagus显示文摘Objective: To analyze the differential expression genes (DEGs) between Barrett’s esophagus (BE) and normal esophagus mucosa and explore the target genes related to the development and progression of BE. Methods: The total RNAs of matched BE and normal esophagus mucosa of BE patients were isolated using one step Trizol method. Matched RNAs were qualified using 10 g/L agarose gel electrophoresis. cRNAs were synthesized, fluorescence labeled and purified after total RNAs were purified. The RNAs of BE and normal esophagus mucosa were hybridized with Agilent oligomicroarray (30 968 probes). The fluorescence intensity features were detected by Agilent scanner and quantified by feature extraction software. Results: (1) The total RNA, reverse transcription product and fluorescence labeled cRNA were all of high quality; (2) There were 142 up-regulated genes and 284 down-regulated genes among 2-fold DEGs. Conclusion: Microarray-based studies are feasible in endoscopically obtained tissues. Many BE-associated genes are screened by the high-throughput gene chip. The development and progression of BE is a complicated process involving multiple genes and multiple procedures, and functional study of these genes may help to identify the key genes or pathways involved in the pathogenesis and development of BE. | Wang Xingwei Sun Yonggang Xu Mei Fang Dianchun Gao Hengjun Xu Jiangtao | 2008 | Journal of Medical Colleges of PLA(China)2008，23，5： | 0 |
| 5 | Benchmark for establishment of organoids from gastrointestinal epithelium and cancer based on available consumables and reagents显示文摘Gastrointestinal cancers are a public health problem that threatens the lives of human being. A good experimental model is a powerful tool to promote the uncovering pathogenesis and establish novel treatment methods. High-quality biomedical research requires experimental models to recapitulate the physiological and pathological states of their parental tissues as much as possible. Organoids are such experimental models. Organoids refer to small organlike cellular clusters formed by the expansion and passaging of living tissues in 3D culture medium in vitro.Organoids are highly similar to the original tissues in terms of cellular composition, cell functions, and genomic profiling. Organoids have many advantages, such as short preparation cycles, long-term storage based on cryopreservation, and reusability. In recent years, researchers carried out the establishment of organoids from gastrointestinal mucosa and cancer tissues, and accumulated valuable experiences. In order to promote effective usage and further development of organoid-related technologies in the research of gastrointestinal diseases, this study proposes a benchmark based on utilization of available experimental consumables and reagents, which are involved in the key steps such as collection and pretreatment of biospecimen, organoid construction, organoid cryopreservation and recovery, growth status evaluation, and organoid quality control. We believe that the standard for the construction and preservation of organoids derived from human gastrointestinal epithelium and cancer tissues can provide an important reference for the majority of scientific researchers. | Ruixin Yang Zhen Xiang Ranlin Yan Wingyan Kwan Lu Zang Zhenggang Zhu Yao Qi Yanping Xu Xiaoyan Zhang Hengjun Gao Yingyan Yu | 2023 | Chinese Journal of Cancer Research2023，35，6： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员