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| 1 | Enhancing plant-microbe associated bioremediation of phenanthrene and pyrene contaminated soil by SDBS-Tween 80 mixed surfactants显示文摘The use of surfactants to enhance plant-microbe associated dissipation in soils contaminated with polycyclic aromatic hydrocarbons(PAHs) is a promising bioremediation technology. This comparative study was conducted on the effects of plant-microbe treatment on the removal of phenanthrene and pyrene from contaminated soil, in the presence of low concentration single anionic, nonionic and anionic-nonionic mixed surfactants. Sodium dodecyl benzene sulfonate(SDBS) and Tween 80 were chosen as representative anionic and nonionic surfactants, respectively. We found that mixed surfactants with concentrations less than 150 mg/kg were more effective in promoting plant-microbe associated bioremediation than the same amount of single surfactants. Only about(m/m) of mixed surfactants was needed to remove the same amount of phenanthrene and pyrene from either the planted or unplanted soils, when compared to Tween 80. Mixed surfactants(< 150 mg/kg) better enhanced the degradation efficiency of phenanthrene and pyrene via microbe or plant-microbe routes in the soils. In the concentration range of 60–150 mg/kg, both ryegrass roots and shoots could accumulate 2–3 times the phenanthrene and pyrene with mixed surfactants than with Tween 80. These results may be explained by the lower sorption loss and reduced interfacial tension of mixed surfactants relative to Tween 80, which enhanced the bioavailability of PAHs in soil and the microbial degradation efficiency. The higher remediation efficiency of low dosage SDBS-Tween 80 mixed surfactants thus advanced the technology of surfactant-enhanced plant-microbe associated bioremediation. | Hewei Ni Wenjun Zhou Lizhong Zhu | 2014 | Journal of Environmental Sciences2014，26，5： | 17 |
| 2 | 实数编码的遗传算法及其在逆变器馈电交流电机中的应用显示文摘实数编码的遗传算法及其在逆变器馈电交流电机中的应用@王秀峰￥南开大学计算机与系统科学系@LuisACabrera@MalikEElbuluk@HeWei遗传算法,神经网络实数编码的遗传算法及其在逆变器馈电交流电机中的应用王秀峰(南开大学计算机与系统科学系天... | 王秀峰 LuisACabrera MalikEElbuluk HeWei | 1998 | 自动化学报1998，24，2： | 6 |
| 3 | The optimized preparation of HA/L-TiO2/D-TiO2 composite coating on porous titanium and its effect on the behavior osteoblasts显示文摘Various surface bioactivation technology has been confirmed to improve the osteogenic ability of porous titanium(pTi)implants effectively.In this study,a three-layered composite coating,i.e.outer layer of hydroxyapatite(HA),middle layer of loose titanium dioxide(L-TiO2)and inner layer of dense TiO2(D-TiO2),was fabricated on pTi by a combined processing procedure of pickling,alkali heat(AH),anodic oxidation(AO),electrochemical deposition(ED)and hydrothermal treatment(HT).After soaking in simulated body fluid for 48 h,the surface of the AHAOEDHT-treated pTi was completely covered by a homogeneous apatite layer.Using MC3T3-E1 pro-osteoblasts as cell model,the cell culture revealed that both the pTi without surface treatment and the AHAOEDHT sample could support the attachment,growth and proliferation of the cells.Compared to the pTi sample,the AHAOEDHT one induced higher expressions of osteogenesis-related genes in the cells,including alkaline phosphatase,Type I collagen,osteopontin,osteoclast inhibitor,osteocalcin and zinc finger structure transcription factor.As thus,besides the good corrosion resistance,the HA/L-TiO2/D-TiO2-coated pTi had good osteogenic activity,showing good potential in practical application for bone defect repair. | Xi Fu Xingyu Zhou Pin Liu Hewei Chen Zhanwen Xiao Bo Yuan Xiao Yang Xiangdong Zhu Kai Zhang Xingdong Zhang | 2020 | Regenerative Biomaterials2020，7，5： | 5 |
| 4 | Construction of a metabolomics profile of arsenic trioxide effect in gastric carcinoma cell line SGC7901显示文摘砷三氧化物(ATO ) 为对待尖锐 promyelocytic 白血病是高度有效的。它也为治疗稳固的肿瘤保持诺言,包括胃的癌。然而,到稳固的肿瘤的 ATO 的有效性的分子的机制仍然糟糕被理解。在这研究,我们 chosed 是的胃的癌一个例子并且试着通过 metabolomics 揭示 antitumor 机制。胃的癌房间线 SGC7901 为 6, 12,和 24 h 与 ATO 被对待。全球代谢物侧面被 metabolomics 分析用气体监视层析(GC )/mass spectrometry (MS ) 和液体层析 /MS/MS。281 的一个总数证明代谢物可靠地被检测。生物信息学分析证明那 glycerophospholipid 合成,一个碳合成,和谷胱甘肽合成戏剧性地被影响。被影响了的另外的细胞的功能 / 小径包括了煽动性的反应,菸碱腺嘌 dinucleotide (NAD +), 和 polyamine 生合成小径。在有以前的 transcriptomics 和 proteomics 数据的联合,从这研究的 metabolomics 数据能为 ATO 处理的特定的 antitumor 机制的理解用作珍贵资源。 | Ziqing Chen Hainan Zhang Lina Yang Hewei Jiang Shujuan Guo Yang Li Shengce Tao | 2016 | Acta Biochimica et Biophysica Sinica2016，48，5： | 5 |
| 5 | Total body irradiation of donors can alter the course of tolerance and induce acute rejection in a spontaneous tolerance rat liver transplantation model显示文摘Liver transplantation is an established therapy for end-stage liver diseases. Graft rejection occurs unless the recipient receives immunosuppression after transplantation. This study aimed to explore the mechanism of acute rejection of liver allografts in rats pre-treated with total body irradiation to eliminate passenger lymphocytes and to define the role of CD4 + CD25 + regulatory T cells in the induction of immunotolerance in the recipient. Male Lewis rats were used as donors and male DA rats were recipients. Rats were randomly assigned to the following four groups: control group, homogeneity liver transplantation group, idio-immunotolerance group and acute rejection group. After transplantation, the survival time of each group, serum alanine aminotransferase, total bilirubin levels, number of Foxp3 + CD4 + CD25 + regulatory T cells, expression of glucocorticoid-induced tumor necrosis factor receptor on T cell subgroups, histopathology of the hepatic graft and spleen cytotoxic T lymphocyte lytic activity were measured. In the acute rejection group, where donors were preconditioned with total body irradiation before liver transplantation, all recipients died between day 17 and day 21. On day 14, serum alanine aminotransferase increased signifi- cantly to (459.2±76.9) U L -1 , total bilirubin increased to (124.1±33.7) μmol L -1 (P<0.05) and the ratio of Foxp3 + CD4 + CD25 + regulatory T cells decreased significantly to 1.50%±0.50% (P<0.05) compared with the other groups. Analysis of the T cell subpopulations in the acute rejection group varied from the other groups. Histological analysis showed typical changes of acute rejection in the acute rejection group only. Preconditioning of the donors with total body irradiation eliminated passenger lymphocytes of the liver graft, and thus affected the course of tolerance and induced acute rejection after liver transplantation. | ZHANG YeWei ZHAO HeWei BO Lin YANG YinXue LU Xiang SUN JingFeng WEN JianFei HE Xia YIN GuoWen | 2012 | Science China(Life Sciences)2012，55，9： | 4 |
| 6 | Calibration of the simulation parameters of the particulate materials in film mixed materials显示文摘In order to obtain accurate contact parameters of a particulate material in residual film mixture collected by cotton field machine in Xinjiang,the angle of repose test and inclined plane test were carried out.In the tests,the angles of repose of the particulate material with the water content of(6.26±1.5)%and(14.1±2.1)%were measured respectively,as well as the static sliding friction angle between the particulate material and the residual film.At the same time,the EDEM software was used to calibrate the coefficient of restitution,static friction coefficient and dynamic friction coefficient between the material and the film.Then,the second-order response model between contact parameters and the angle of repose and static sliding friction angle was constructed.In addition,the optimal contact parameters between the granular materials and the mulch were obtained by fitting the physical test data.The results indicated that the errors between the physical test results and the numerical simulation results are small.It was proved that the second-order response model could predict the repose angle of granular materials and the static sliding friction angle between granular materials and farmland film.This study could provide theoretical support for the subsequent model construction of the residual film mixture collected by the cotton field machine. | Rongqing Liang Xuegeng Chen Peng Jiang Bingcheng Zhang Hewei Meng Xiangbin Peng Za Kan | 2020 | International Journal of Agricultural and Biological Engineering2020，13，4： | 3 |
| 7 | Adsorption of rubidium ion from aqueous solution by surface ion imprinted materials显示文摘A new type of rubidium ion-imprinted polymer has been synthesized by the surface-imprinting technique using methacrylic acid as the functional monomer,the rubidium ion as the template,methanol as the solvent,and silica as a carrier.Ethylene glycol dimethacrylate and 2,2-azobisisobutyronitrile were used as acrosslinker and an initiator,respectively.In addition,based on the macrocyclic effect of crown ethers,the 18-crown-6 ligand was introduced as a ligand to fix the template ions better.Scanning electron microscopy,zeta-potential analysis,Fourier transform infrared spectroscopy,thermogravimetric analysis,and X-ray photoelectron spectroscopy were performed to characterize the ion-imprinted polymer.The effects of the preparation and adsorption conditions on the adsorption performance of the rubidium ion-imprinted polymer were investigated.The results indicated that the rubidium ion-imprinted polymer has high selectivity and faster kinetics than other adsorbents,with an equilibrium adsorption capacity of 200.19 mg·g^(-1)at 298 K within 25 min.The sorption isotherm was well described by the Freundlich isotherm model,while the adsorption kinetics fitted the pseudo-second-order kinetic model.Consecutive adsorption-desorption experiments showed that the ion-imprinted polymer had good chemical stability and reusability. | Zhongqi Ren Jie Wang Hewei Zhang Fan Zhang Shichao Tian Zhiyong Zhou | 2023 | Chinese Journal of Chemical Engineering2023，54，2： | 3 |
| 8 | Evaluation on the corrosion resistance, antibacterial property and osteogenic activity of biodegradable Mg-Ca and Mg-Ca-Zn-Ag alloys显示文摘The rapid degradation of magnesium(Mg)-based implants in physiological environment limits its clinical applications, and alloying treatment is an effective way to regulate the degradation rate of Mg-based materials. In the present study, three Mg alloys, including Mg-0.8Ca(denoted as ZQ), Mg-0.8Ca-5Zn-1.5Ag(denoted as ZQ71) and Mg-0.8Ca-5Zn-2.5Ag(denoted as ZQ63), were fabricated by alloying with calcium(Ca), zinc(Zn) and silver(Ag). The results obtained from electrochemical corrosion tests and in vitro degradation evaluation demonstrated that the three Mg alloys exhibited distinct corrosion resistance, and ZQ71 exhibited the lowest degradation rate in vitro among them. After addition of Zn and Ag, the antibacterial potential of Mg alloys was also enhanced. The in vitro cell experiments showed that all the three Mg alloys had good biocompatibility. After implantation in a rat femoral defect, ZQ71 showed significantly higher osteogenic activity and bone substitution rate than ZQ63 and ZQ, due to its higher corrosion resistance as well as the stimulatory effects of the released metallic ions. In addition, the average daily degradation rate of each Mg alloy in vivo was significantly higher than that in vitro, as could be due to the implantation site located in the highly vascularized trabecular region. Importantly, the correlations between the in vitro and in vivo degradation parameters of the Mg alloys were systematically analyzed to find out the potential predictors of the in vivo degradation performance of the materials. The current work not only evaluated the clinical potential of the three biodegradable Mg alloys as bone grafts but also provided a feasible approach for predicting the in vivo degradation behavior of biodegradable materials. | Hewei Chen Bo Yuan Rui Zhao Xiao Yang Zhanwen Xiao Antoniac Aurora Bita Ana Iulia Xiangdong Zhu Antoniac Vasile Iulian Xingdong Zhang | 2022 | Journal of Magnesium and Alloys2022，10，12： | 3 |
| 9 | Operation power consumption and verification tests of a trenching device for orchards in Xinjiang based on discrete element显示文摘According to the agronomic requirements of orchard planting pattern and fertilization in Xinjiang,the soil particle models and a soil-trenching device interaction model were established by using discrete element simulation software in order to find out the law of influence of structure parameters and working parameters on the operation power consumption of a segmented cutting trenching device;moreover,its cutting process was simulated according to the response surface test design.According to the results of research on the influence of forward speed,cutter disk speed and cutter disk combination on the operation power consumption of the segmented cutting trenching device,the law of their influence on the operation power consumption in descending order is forward speed,cutter disk combination,cutter disk speed.According to the response surface test result,the following influential factor parameter combination has been obtained:forward speed 815 m/h,cutter disk speed 112 r/min,cutter disk combination A(cut angle 150°,bent angle 60°and working width 133 mm),cutter disk combination B(cut angle 180°,bent angle 90°and working width 166 mm),and trenching operation power consumption-optimization results were verified through field tests.According to the verification,the results showed a high accuracy of the simulation,with a relative error mean of 3.18%between the theoretical value and the field test value.This study can provide a reference for the energy-saving design of orchard trenching devices. | Chen Ma Jiangtao Qi Za Kan Shaojie Chen Hewei Meng | 2021 | International Journal of Agricultural and Biological Engineering2021，14，1： | 3 |
| 10 | Magmatic Evolution and Mineralization Process of the Super-Large Shihuiyao Rb–Nb–Ta Deposit,Southern Great Xing'an Range,China显示文摘Objective Rare metal ore reserves are an important strategic resource,and their metallogenic mechanism and mineralization studies have also been received widespread international attention.The Shihuiyao super-large Rb-Nb-Ta deposit from the Southern Great Xing’an Range,NE China is the world’s largest Rb deposit,whose | ZHOU Zhenhua CHE Hewei MA Xinghua GAO Xu | 2016 | Acta Geologica Sinica(English Edition)2016，90，6： | 2 |
| 11 | Blue emitting CsPbBr3 perovskite quantum dot inks obtained from sustained release tablets显示文摘Blue emitting perovskite ink obtained from cesium lead halide quantum dots bearing chlorine(CsPbClxBr3-x,0 | Hewei Yang Yaqing Feng Zhiyu Tu Kuo Su Xiaozhi Fan Bingjie Liu Zhiping Shi Yuzhe Zhang Chenyang Zhao Bao Zhan | 2019 | Nano Research2019，12，12： | 2 |
| 12 | Construction of a magnesium hydroxide/graphene oxide/hydroxyapatite composite coating on Mg-Ca-Zn-Ag alloy to inhibit bacterial infection and promote bone regeneration显示文摘The improved corrosion resistance, osteogenic activity, and antibacterial ability are the key factors for promoting the large-scale clinical application of magnesium (Mg)-based implants. In the present study, a novel nanocomposite coating composed of inner magnesium hydroxide, middle graphene oxide, and outer hydroxyapatite (Mg(OH)_(2)/GO/HA) is constructed on the surface of Mg-0.8Ca-5Zn-1.5Ag by a combined strategy of hydrothermal treatment, electrophoretic deposition, and electrochemical deposition. The results of material characterization and electrochemical corrosion test showed that all the three coatings have high bonding strength, hydrophilicity and corrosion resistance. In vitro studies show that Mg(OH)2 indeed improves the antibacterial activity of the substrate. The next GO and GO/HA coating procedures both promote the osteogenic differentiation of MC3T3-E1 cells and show no harm to the antibacterial activity of Mg(OH)2 coating, but the latter exhibits the best promoting effect. In vivo studies demonstrate that the Mg alloy with the composite coating not only ameliorates osteolysis induced by bacterial invasion but also promotes bone regeneration under both normal and infected conditions. The current study provides a promising surface modification strategy for developing multifunctional Mg-based implants with good corrosion resistance, antibacterial ability and osteogenic activity to enlarge their biomedical applications. | Bo Yuan Hewei Chen Rui Zhao Xuangeng Deng Guo Chen Xiao Yang Zhanwen Xiao Antoniac Aurora Bita Ana Iulia Kai Zhang Xiangdong Zhu Antoniac Vasile Iulian Shen Hai Xingdong Zhang | 2022 | Bioactive Materials2022，7，12： | 2 |
| 13 | Effects of Epstein-Barr virus infection on the development of multiple myeloma after liver transplantation显示文摘Reduced cellular immune function in patients after liver transplantation easily results in many types of viral infections,such as Epstein-Barr virus.Epstein-Barr virus is a γ-herpesvirus and is related to many malignant diseases,especially epithelial and lymph tumors.The abnormal interaction of cluster of differentiation 40 with cluster of differentiation 40 ligand and expression of cluster of differentiation 40 ligand are considered closely related to the development of myeloma cells.This study explored the influence and mechanism of Epstein-Barr virus infection on the phenotype and biological behavior of myeloma cells after liver transplantation.Flow cytometry was used to detect coexpression of cluster of differentiation 40 and cluster of differentiation 40 ligand in 10 samples of freshly isolated multiple myeloma cells.Cluster of differentiation 40 and cluster of differentiation 40 ligand were coexpressed in sample Nos.5,8,9,and 10,particularly in sample No.5.Western blot analysis was used to detect the expression of the Epstein-Barr virus antigens latent membrane protein 1 and Epstein-Barr virus nuclear antigen 2 in the multiple myeloma cell line RPMI 8226 infected with Epstein-Barr virus.The antigen expression indicated that Epstein-Barr virus can infect multiple myeloma virus cells in vitro.Reverse transcription-polymerase chain reaction revealed upregulated expression of cluster of differentiation 40 ligand on the infected RPMI 8226 cells,which may be involved in the anti-apoptosis activity of the infected cells.Confocal microscopy showed that pairs of molecules of cluster of differentiation 40,cluster of differentiation 40 ligand,and latent membrane protein 1 were colocalized on the surface of the infected cells.CXC chemokine receptor 4 was upregulated on the RPMI 8226 cells after Epstein-Barr virus infection.The migratory ability of the infected cells improved in the presence of the chemokine stromal cell-derived factor-1α.Anti-apoptosis and migration are known important biological characteristics of malignant cells.Our results indicate the involvement of Epstein-Barr virus in the origin and development of multiple myeloma.The risk of multiple myeloma increases when Epstein-Barr virus infects B cells in the germinal center,which may result in an anti-apoptosis effect of B cells and an improved ability to migrate from the germinal center to peripheral blood. | ZHANG YeWei ZHAO HeWei HE Xia ZHENG SuWen WANG TaiHong YAN DongLiang SUN JingFeng LU Xiang WEN JianFei LAU Wan Yee | 2012 | Science China(Life Sciences)2012，55，8： | 2 |
| 14 | Effect of the pineal gland on 5-hydroxytryptamine and γ-aminobutyric acid secretion in the hippocampus of male rats during the summer and winter显示文摘Objective:The present study aimed to investigate the effect of seasonal variation on neurotransmitter release in the hippocampus of normal rats and rats with pineal excision.Methods:Two time points,the summer and winter solstice,which are the longest and shortest days of the year,respectively,were selected.Male Spraguee Dawley rats that underwent a sham operation without pineal excision were included as a control group.The concentrations of 5-hydroxytryptamine(5-HT)andγ-aminobutyric acid(GABA)were determined by radioimmunoassays and enzyme-linked immunosorbent assays,respectively.Results:In the winter,the 5-HT and GABA levels in normal rats exhibited a significant difference compared with those in the operation group(P<.01).A difference was also noted in GABA levels between the normal group and the sham operation group(P<.05).The concentrations of 5-HT and GABA in the hippocampal tissues of the normal group exhibited a seasonal rhythm consisting of elevation during the summer and reduction during the winter(P<.01),while the GABA levels in the sham operation group exhibited a significant difference,with elevation during the summer and reduction during the winter(P<.01).In the operation group,GABA showed the same trend(P<.01).Conclusion:The seasonal rhythm of neurotransmitter secretion by the hippocampus(5-HT and GABA)consisted of elevation during the summer and reduction during the winter.During the winter,the pineal gland exhibited a reverse regulatory effect on the secretion of 5-HT and GABA in the hippocampus,and it exhibited seasonal selectivity with regard to the regulation of 5-HT. | Ting Li Hailu Wang Hewei Zhang Leilei Liu Peipei Li Shuran Ma | 2020 | Journal of Traditional Chinese Medical Sciences2020，7，3： | 2 |
| 15 | The Time-Synchronous Dynamic Programming Approach to the Shortest Path Search in Spoken Dialog System显示文摘Shortest path search has important practical applications and is related to optimization problem.This paper discusses a new algorithm time-synchronous heuristic dynamic programming search, which combined the pruning and global optimization of DP (Dynamic programming) and the partial search of heuristic strategy and found the shortest path in time O(n/k^d) (k, d ≥ 1). Furthermore, the algorithm can be applied to find the K shortest paths between a pair of given nodes or all paths less than a given length within the same steps. Finally this algorithm was applied to the shortest path search on the real map and user could use spoken dialog to query shortcut in realtime, 90% of the system responses are correct. | HEWei YANGSuqiong YUANBaozong LINBiqin | 2004 | Chinese Journal of Electronics2004，13，2： | 1 |
| 16 | Inhibitory effect of Sumu(Lignum Sappan) plus Fuzi(Radix Aconiti Lateralis Praeparata) on a lung carcinoma model显示文摘OBJECTIVE: To investigate the inhibitory effect of Sumu(Lignum Sappan) plus Fuzi(Radix Aconiti Lateralis Praeparata)(SF) on the growth and metastasis of Lewis lung carcinoma.METHODS: A lung carcinoma model was established by subcutaneously inoculating Lewis lung carcinoma cells into C57 BL/6 mice. The mice were randomly divided into four groups of 13 mice(control, low-dose, moderate-dose, and high-dose), and gavaged once-daily for 21 consecutive days. The rates of tumor inhibition, metastasis, and metastasis inhibition were observed. The differential expressions of s P-selectin and vascular endothelial growth factor C(VEGFC) were compared between the treatment groups and the control group.RESULTS: The tumor weights differed significantly between the treatment groups and the control group(P < 0.05). Administration of SF in the moderate-dosage and low-dose groups significantly inhibited the expression of s P-selectin and VEGFC(both P < 0.05), suggesting anti-tumor activity.CONCLUSION: SF can inhibit the growth and metastasis of Lewis lung carcinoma. | Zhang Hewei Ma Shuran Tian Tian Xu Ya Zhao Dandan Wang Tong Hou Chunying Zhang Shujing | 2018 | Journal of Traditional Chinese Medicine2018，38，2： | 1 |
| 17 | 显示文摘 | HeWei(何伟) QiHaibo(齐海波) LinFeng(林峰)etal | 2006 | 电加工与模具2006，1，： | 1 |
| 18 | Towards Responsive Single-Molecule Device显示文摘Single-molecule devices,which are fabricated by the single molecule bridged through electrodes,provide a promising approach to investigate the intrinsic chemical or physical properties of individual molecules.Beyond the studies of single-molecule wires,a large number of responsive single-molecule junctions or devices with unique chemical or physical properties have been designed and fabricated by introducing the external field,which further offers the chance to explore conductive materials at the molecular level.Here,we summarized the latest studies on the behaviors of single-molecule devices based on the photon,thermal,electric,or magnetic responses,and discussed the development of responsive single-molecule devices in prospect. | Yaorong Chen Longfeng Huang Hang Chen Zhixin Chen Hewei Zhang Zongyuan Xiao Wenjing Hong | 2021 | Chinese Journal of Chemistry2021，39，2： | 1 |
| 19 | An Attenuated Highly Pathogenic Chinese PRRS Viral Vaccine Confers Cross Protection to Pigs against Challenge with the Emerging PRRSV NADC30-Like Strain显示文摘A novel PRRSV strain was isolated in China that was genetically similar to the NADC30 strain which is reported to have spread throughout China. The objective of the present study was to evaluate the cross-protective efficacy of the live vaccine TJM-F92 in young pigs against challenge with a NADC30-like strain, HN201605. Twenty-five PRRSV-and antibody-free pigs were randomly divided into the following five groups: Vac/ChA, Unvac/ChA, Vac/ChB, Unvac/ChB and the mock.The pigs in groups Vac/ChA and Vac/ChB were inoculated intramuscularly with 1 mL TJM-F92(10^(5.0) TCID_(50)/mL). At28 days post vaccination(0 days post challenge), groups Vac/ChA and Unvac/ChA were inoculated intranasally with 10^(4.5) TCID_(50)/mL PRRSV strain TJ F3(2 mL/pig), while groups Vac/ChB and Unvac/Ch B were inoculated, using the same route, with the same dose of the NADC30-like strain HN201605 F3. Protective effects of the PRRSV strain were observed in all pigs in the Vac/ChA and Vac/ChB groups. Neither high fever nor signs of clinical disease were observed through the experiment in these groups, whereas pigs in Unvac/ChA group exhibited serious clinical symptoms, pathological lesions,and weight loss. In Unvac/ChB group, pigs developed milder clinical symptoms, which demonstrated that the NADC30-like strain HN201605 had moderate pathogenicity. The results suggest that the MLV vaccine strain TJM-F92 is an effective and safe vaccine candidate for use in China. | Hewei Zhang Mingqi Xia Wei Wang Decai Ju Long Cao Bai Wu Xin Wang Ying Wu Ni Song Jiaxin Hu Changxiao Tian Shucheng Zhang Hua Wu | 2018 | Virologica Sinica2018，33，2： | 1 |
| 20 | Wet Chemical Synthesis of Amorphous Nanomaterials with Well-Defined Morphologies显示文摘CONSPECTUS:Amorphous nanomaterials,with unique structural features such as long-range atomic disorder and nanoscale particle or grain sizes,possess some advantageous properties for a number of materials applications.For example,amorphous vanadium oxide exhibits a record-high cycling stability for supercapacitors.Several synthetic strategies have been developed to produce amorphous nanomaterials,such as physical processing-based approaches including cutting,deposition,and spinning,as well as chemical syntheses by solution or solid state reactions.However,despite the rapid development of amorphous nanomaterials,their morphology is still irregular or primarily sphere-like.The limited morphology control is partially attributed to the lack of preferred growth direction for the amorphous materials.It will be interesting to know whether different morphologies of even amorphous nanomaterials can influence their properties as much as their crystalline counterparts.Wet chemical synthesis,which can usually be carried out under relatively facile reaction conditions,has achieved remarkable success for creating crystalline nanomaterials with well-defined shapes,such as one-dimensional(1D)nanowires,two-dimensional(2D)nanosheets,and three-dimensional(3D)complex structures.However,there are two main obstacles for shape control of amorphous nanomaterials using wet chemical strategies.First,it is difficult to form a stable amorphous state under wet chemical conditions.The amorphous state is metastable in solution according to classic nucleation theory,which is prone to phase transformation to form crystalline state.Second,common morphology control mechanisms for nanocrystals are ultimately relying on the intrinsic directionality of the lattices,which unfortunately is not relevant to the isotropic amorphous nanomaterials.In this Account,we describe how shape control of 1D,2D,and 3D amorphous nanomaterials can be achieved in wet chemical synthesis to create well-defined morphologies,which are based on two main strategies:Blocking agents that can stabilize the amorphous state in solution,and morphology-tunable parameters that can induce directional growth.Discussion on the phase transfer blocking mechanisms includes lattice disordering,controlled hydrolysis,rapid reaction,and ionic exchange,and for morphology control through confinement it includes precursor transformation,templated reactions,interfacial etching,and spatial confinement.In addition,we present examples showing how these well-defined morphology leads to desirable properties in applications of mechanics,energy storage,catalysis,and optics,highlighting their structural-properties relationship.Finally,some perspectives are discussed regarding future research opportunities in the area of amorphous nanomaterials. | Hewei Zhao Fengshi Li Shaoxiong Wang Lin Guo | 2021 | Accounts of Materials Research2021，2，9： | 1 |
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