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| 1 | Vehicular volatile organic compounds losses due to refueling and diurnal process in China: 2010–2050显示文摘Volatile organic compounds(VOCs) are crucial to control air pollution in major Chinese cities since VOCs are the dominant factor influencing ambient ozone level, and also an important precursor of secondary organic aerosols. Vehicular evaporative emissions have become a major and growing source of VOC emissions in China. This study consists of lab tests, technology evaluation, emissions modeling, policy projections and cost-benefit analysis to draw a roadmap for China for controlling vehicular evaporative emissions. The analysis suggests that evaporative VOC emissions from China's light-duty gasoline vehicles were approximately 185,000 ton in 2010 and would peak at 1,200,000 ton in 2040 without control. The current control strategy implemented in China, as shown in business as usual(BAU) scenario, will barely reduce the long-term growth in emissions. Even if Stage II gasoline station vapor control policies were extended national wide(BAU + extended Stage II), there would still be over 400,000 ton fuel loss in 2050. In contrast, the implementation of on-board refueling vapor recovery(ORVR) on new cars could reduce 97.5% of evaporative VOCs by 2050(BAU + ORVR/BAU + delayed ORVR). According to the results, a combined Stage II and ORVR program is a comprehensive solution that provides both short-term and long-term benefits. The net cost to achieve the optimal total evaporative VOC control is approximately 62 billion CNY in 2025 and 149 billion CNY in 2050. | Xiaofan Yang Huan Liu Hongyang Cui Hanyang Man Mingliang Fu Jiming Hao Kebin He | 2015 | Journal of Environmental Sciences2015，27，7： | 19 |
| 2 | High-Efficiency Reduction of Rice Amylose Content via CRISPR/Cas9-Mediated Base Editing显示文摘Rice is a staple food for more than half of the human population.It has been estimated that by 2030,rice production must increase by 40%to meet the growing demand(Khush,2005).In addition,with the improvement of people's living standards,the demand for elite rice with better eating and cooking quality(ECQ)is increasing.ECQ is determined by several factors,including amylose content(AC),gel consistency(GC),gelatinization temperature(GT)and viscosity,where AC is the predominant factor(Juliano,1998). | Li He Li Xiufeng Xu Yang Liu Hualong He Mingliang Tian Xiaojie Wang Zhenyu Wu Xiuju Bu Qingyun Yang Jie | 2020 | Rice science2020，27，6： | 7 |
| 3 | Role of Wnt and Notch signaling in regulating hair cell regeneration in the cochlea显示文摘在内耳的感觉毛细胞为健全识别负责。因为这些房间不能再生,在成年哺乳动物的毛细胞的损坏引起永久听觉缺陷。由对比,因为各种各样的发信号的小径的活跃参予,新生的哺乳动物拥有有限再生能力,包括 Wnt 并且槽口发信号。Wnt 和槽口小径高度复杂、保存表明控制为感觉毛细胞的形成必要的多重细胞的事件的小径。两个都发信号的小径允许支持房间在新生的蜗改革毛细胞的居民。在这方面, Wnt 并且槽口发信号在毛细胞新生获得了增加的研究注意。这评论在内耳的听觉的部分介绍 Wnt 和槽口发信号小径的当前的理解并且讨论与毛细胞命运限定词 Atoh1 控制这些小径在哺乳动物的蜗调整毛细胞新生的可能性。 | Muhammad Waqas Shasha Zhang Zuhong He Mingliang Tang Renjie Chai | 2016 | Frontiers of Medicine2016，10，3： | 7 |
| 4 | OsMKKK70 regulates grain size and leaf angle in rice through the OsMKK4-OsMAPK6-OsWRKY53 signaling pathway显示文摘Grain size and leaf angle are key agronomic traits that determine final yields in rice.However,the underlying molecular mechanisms are not well understood.Here we demonstrate that the Oryza sativa Mitogen Activated Protein Kinase Kinase Kinase OsMKKK70 regulates grain size and leaf angle in rice.Overexpressing OsMKKK70 caused plants to produce longer seeds.The osmkkk62/70 double mutant and the osmkkk55/62/70 triple mutant displayed significantly smaller seeds and a more erect leaf angle compared to the wild type,indicating that OsMKKK70 functions redundantly with its homologs Os MKKK62 and Os MKKK55.Biochemical analysis demonstrated that OsMKKK70 is an active kinase and that OsMKKK70 interacts with Os MKK4 and promotes Os MAPK6 phosphorylation.In addition,the osmkkk62/70 double mutant showed reduced sensitivity to Brassinosteroids(BRs).Finally,overexpressing constitutively active Os MKK4,Os MAPK6,and Os WRKY53 can partially complement the smaller seed size,erect leaf,and BR hyposensitivity of the osmkkk62/70 double mutant.Taken together,these findings suggest that OsMKKK70 might regulate grain size and leaf angle in rice by activating Os MAPK6 and that OsMKKK70,Os MKK4,Os MAPK6,and Os WRKY53 function in a common signaling pathway that controls grain shape and leaf angle. | Zhiqi Liu Enyang Mei Xiaojie Tian Mingliang He Jiaqi Tang Min Xu Jiali Liu Lu Song Xiufeng Li Zhenyu Wang Qingjie Guan Qijiang Xu Qingyun Bu | 2021 | Journal of Integrative Plant Biology2021，63，12： | 6 |
| 5 | A complex structure of arrestin-2 bound to a G protein-coupled receptor显示文摘Arrestins comprise a family of signal regulators of G-protein-coupled receptors(GPCRs),which include arrestins 1 to 4.While arrestins 1 and 4 are visual arrestins dedicated to rhodopsin,arrestins 2 and 3(Arr2 and Arr3)areβ-arrestins known to regulate many nonvisual GPCRs.The dynamic and promiscuous coupling of Arr2 to nonvisual GPCRs has posed technical challenges to tackle the basis of arrestin binding to GPCRs.Here we report the structure of Arr2 in complex with neurotensin receptor 1(NTSR1),which reveals an overall assembly that is strikingly different from the visual arrestin–rhodopsin complex by a 90°rotation of Arr2 relative to the receptor.In this new configuration,intracellular loop 3(ICL3)and transmembrane helix 6(TM6)of the receptor are oriented toward the N-terminal domain of the arrestin,making it possible for GPCRs that lack the C-terminal tail to couple Arr2 through their ICL3.Molecular dynamics simulation and crosslinking data further support the assembly of the Arr2‒NTSR1 complex.Sequence analysis and homology modeling suggest that the Arr2‒NTSR1 complex structure may provide an alternative template for modeling arrestin–GPCR interactions. | Wanchao Yin Zhihai Li Mingliang Jin Yu-Ling Yin Parker Wde Waal Kuntal Pal Yanting Yin Xiang Gao Yuanzheng He Jing Gao Xiaoxi Wang Yan Zhang Hu Zhou Karsten Melcher Yi Jiang Yao Cong X.Edward Zhou Xuekui Yu H.Eric Xu | 2019 | Cell Research2019，29，12： | 4 |
| 6 | Oryza sativa mediator subunit OsMED25 interacts with OsBZR1 to regulate brassinosteroid signaling and plant architecture in rice显示文摘Brassinosteroids(BRs)are plant-specific steroid hormones which regulate plant growth,development,and adaptation.Transcriptional regulation plays key roles in plant hormone signaling.A mediator can serve as a bridge between gene-specific transcription factors and the RNA polymerase machinery,functioning as an essential component in regulating the transcriptional process.However,whether a mediator is involved in BR signaling is unknown.Here,we discovered that Oryza sativa mediator subunit 25(Os MED25)is an important regulator of rice BR signaling.Phenotypic analyses showed that the Os MED25-RNAi and osmed25 mutant presented erect leaves,as observed in BR-deficient mutants.In addition,the Os MED25-RNAi and osmed25 mutant exhibited decreased BR sensitivity.Genetic analysis indicated that Os MED25-RNAi could suppress the enhanced BR signaling phenotype of Osbzr1-D.Further biochemical analysis showed that Os MED25 interacts with Os BZR1 in vivo,and Os MED25 is enriched on the promoter of Os BZR1 target genes.RNA sequencing analysis indicated that Os MED25 affects the expression of approximately 45%of Os BZR1-regulated genes and mainly functions as a corepressor of Os BZR1.Together,these findings revealed that Os MED25 regulates rice BR signaling by interacting with Os BZR1 and modulating the expression of Os BZR1 target genes,thus expanding our understanding of the roles of mediators in plant hormone signaling. | Yuekun Ren Xiaojie Tian Shuyu Li Enyang Mei Mingliang He Jiaqi Tang Min Xu Xiufeng Li Zhenyu Wang Chuanyou Li Qingyun Bu | 2020 | Journal of Integrative Plant Biology2020，62，6： | 3 |
| 7 | NUPR1 promotes the proliferation and metastasis of oral squamous cell carcinoma cells by activating TFE3-dependent autophagy显示文摘Oral squamous cell carcinoma(OSCC)is the most common type of oral malignancy,and metastasis accounts for the poor prognosis of OSCC.Autophagy is considered to facilitate OSCC development by mitigating various cellular stresses;nevertheless,the mechanisms of autophagy in OSCC cell proliferation and metastasis remain unknown.In our study,high-sensitivity label-free quantitative proteomics analysis revealed nuclear protein 1(NUPR1)as the most significantly upregulated protein in formalin-fixed paraffin-embedded tumour samples derived from OSCC patients with or without lymphatic metastasis. | Tengfei Fan Xiaoning Wang Sheng Zhang Ping Deng Yi Jiang Yidan Liang Sheng Jie Qing Wang Chuwen Li Guocai Tian Zhen Zhang Zhenhu Ren Bo Li Yanrong Chen Zhijing He Yan Luo Mingliang Chen Hanjiang Wu Zhengping Yu Huifeng Pi Zhou Zhou Zhiyuan Zhang | 2022 | Signal Transduction and Targeted Therapy2022，7，5： | 2 |
| 8 | Corrosion Behavior of Anodic Oxidized TiO_2 Film in Seawater显示文摘TiO2 films were formed on metallic titanium substrates by the anodic oxidation method in H2SO4 solution under the 80V D.C..Phase component and microstructure were characterized by X-ray diffraction (XRD) and scanning electron microscopy (SEM).Water contact angles on titanium oxide film surface were measured under both dark and sunlight illumination conditions.Corrosion tests were carried out in seawater under different illumination conditions by electrochemistry impedance spectrum (EIS) and polarization curves.The result showed that the TiO2 film prepared by the anodic oxidation method was anatase with a uniform structure and without obvious pores or cracks on its surface.The average water contact angle of the film was 116.4? in dark, in contrast to an angle of 42.7? under the UV illumination for 2 hours, which demonstrates good hydrophobic property.The anti-corrosion behavior of the TiO2 film was declining with the extended immersion time.Under dark conditions, however, the hydrophobic TiO2 film retarded the water infiltrating into the substrate.The impedance changed slowly and the corrosion current density was 2 orders of magnitude lower than that with the film illuminated by sunlight.All of those mentioned above indicate that the TiO2 film possesses much better performance under dark condition, and it can be applied as an engineering material under dark seawater environment. | WANG Min WANG Wei HE Benlin SUN Mingliang YIN Yansheng LIU Lan ZOU Wuyuan XU Xuefei | 2010 | Journal of Ocean University of China2010，9，4： | 2 |
| 9 | Plasmonic coupling-enhanced in situ photothermal nanoreactor with shape selective catalysis for C–C coupling reaction显示文摘Carbon-carbon(C–C)coupling reactions represent one of the most powerful tools for the synthesis of complex natural products,bioactive molecules developed as drugs and agrochemicals.In this work,a multifunctional nanoreactor for C–C coupling reaction was successfully fabricated via encapsulating the core-shell Cu@Ni nanocubes into ZIF-8(Cu@Ni@ZIF-8).In this nanoreactor,Ni shell of the core-shell Cu@Ni nanocubes was the catalytical active center,and Cu core was in situ heating source for the catalyst by absorbing the visible light.Moreover,benefiting from the plasmonic resonance effect between Cu@Ni nanocubes encapsulated in ZIF-8,the absorption range of nanoreactor was widened and the utilization rate of visible light was enhanced.Most importantly,the microporous structure of ZIF-8 provided shape-selective of reactant.This composite was used for the highly shape-selective and stable photocatalysed C–C coupling reaction of boric acid under visible light irradiation.After five cycles,the nanoreactor still remained high catalytical activity.This Cu@Ni@ZIF-8 nanoreactor opens a way for photocatalytic C–C coupling reactions with shape-selectivity. | Zhenxing Li Yixuan Gong Xin Zhang Yangyang Wen Jiasai Yao Mingliang Hu Miao He Jiahao Liu Rui Li Fuqiang Wang Chuanxin Zhang | 2020 | Nano Research2020，13，10： | 2 |
| 10 | bZIP71 delays flowering by suppressing Ehd1 expression in rice显示文摘Flowering time is a fundamental factor determining the global distribution and final yield of rice(Oryza sativa).Although diverse flowering time genes have been reported in this crop,the transcriptional regulation of its key flowering genes are poorly understood.Here,we report that a basic leucine zipper transcription factor,bZIP71,functions as a flowering repressor.The overexpression of bZIP71 delays flowering,while the bzip71 mutant flowers early in both long-day and short-day conditions.A genetic analysis showed that the regulation of flowering by bZIP71 might be independent of Heading date 2(Hd2),Hd4,and Hd5.Importantly,bZIP71 directly associates with the Early heading date 1(Ehd1)promoter and represses its transcription,and genetically the function of bZIP71 is impaired in the ehd1 mutant.Moreover,bZIP71 interacts with major components of polycomb repressive complex 2(PRC2),SET domain group protein 711(SDG711),and Fertilization independent endosperm 2(FIE2),through which bZIP71 regulates the H3K27me3 level of Ehd1.Taken together,we present a transcriptional regulatory mechanism in which bZIP71 enhances the H3K27me3 level of Ehd1 and transcriptionally represses its expression,which not only offers a novel insight into a flowering pathway,but also provides a valuable putative target for the genetic engineering and breeding of elite rice cultivars. | Xiufeng Li Xiaojie Tian Mingliang He Xinxin Liu Zhiyong Li Jiaqi Tang Enyang Mei Min Xu Yingxiang Liu Zhenyu Wang Qingjie Guan Wei Meng Jun Fang Jian Zhang Qingyun Bu | 2022 | Journal of Integrative Plant Biology2022，64，7： | 2 |
| 11 | Pharmacological inhibition of SRC-1 phase separation suppresses YAP oncogenic transcription activity显示文摘Dear Editor,Yes-associated protein(YAP)is a transcriptional coactivator that plays an essential role in promoting cell proliferation,development and stem cell fate.1 Aberrant YAP activation is prevalent in diverse types of human solid cancers. | Guangya Zhu Jingjinq Xie Zhenzhen Fu Mingliang Wang Qichen Zhang Hao He Zijun Chen Xin Guo Jidong Zhu | 2021 | Cell Research2021，31，9： | 2 |
| 12 | Mesoporous silica stabilized MOF nanoreactor for highly selective semi-hydrogenation of phenylacetylene via synergistic effect of Pd and Ru single site显示文摘Selective semi-hydrogenation of phenylacetylene to styrene is a crucial step in the polystyrene industry.Although Pd-based catalysts are widely used in this reaction due to their excellent hydrogenation activity,the selectivity for styrene remains a great challenge.Herein,we designed a mesoporous silica stabilized Pd-Ru@ZIF-8(MS Pd-Ru@ZIF-8)nanoreactor with novel Pd and Ru single site synergistic catalytical system for semi-hydrogenation of phenylacetylene.The nanoreactor exhibited a superior performance,achieving 98%conversion of phenylacetylene and 96%selectivity to styrene.Turnover frequency(TOF)of nanoreactor was up to as high as 2,188 h^(−1),which was 25 times and 5 times more than the single metal species catalysts,mesoporous silica stabilized Pd@ZIF-8 nanoreactor(MS Pd@ZIF-8),and mesoporous silica stabilized Ru@ZIF-8 nanoreactor(MS Ru@ZIF-8).This catalytic activity was attributed to the synergistic effect of Pd and Ru single site anchored strongly into the framework of ZIF-8,which reduced the desorption energy of styrene and increased the hydrogenation energy barrier of styrene.Importantly,since the ordered mesoporous silica was introduced into the nanoreactor shell to stabilize ZIF-8,MS Pd-Ru@ZIF-8 showed excellent reusability and stability.After the five cycles,the catalytical activity and selectivity still remained.This work provides insights for a synergistic catalytic system based on single-site active sites for selective hydrogenation reactions. | Zhenxing Li Mingliang Hu Jiahao Liu Weiwei Wang Yanjie Li Wenbin Fan Yixuan Gong Jiasai Yao Ping Wang Miao He Yongle Li | 2022 | Nano Research2022，15，3： | 2 |
| 13 | Non isothermal Crystallization Kinetics of Polypropylene/Montmorillonite Nanocomposites显示文摘 | Weibing Xu Mingliang Ge Pingsheng He | 2002 | J Polym Sci Part B Polym Phys2002，40，5： | 1 |
| 14 | Boosting the Photocatalytic Activity of WO3 by Highly Dispersed CoWO4 or CuWO4显示文摘WO3 photocatalyst decorated with highly dispersed CoWO4 or CuWO4 nanoparticles(CoWO4/WO3 or CuWO4/WO3) was successfully synthesized using an in-situ impregnation method followed by solid-state reaction. The structure, morphology, photophysical property, and photocatalytic degradation mechanism of the CoWO4/WO3 or CuWO4/WO3 samples were investigated by XRD, SEM, TEM, EDS, HR-TEM, UV-vis DRS, SPV, and active trapping techniques. The XRD, SEM, and TEM results have revealed that CoWO4 or CuWO4 are highly dispersed on the WO3 surface, when the loading amount of CoWO4 or CuWO4 is small. However, obvious agglomeration is observed for the CoWO4 or CuWO4 particles, when the loading amount of CoWO4 or CuWO4 was increased. The visible-light photocatalytic degradation of RhB shows that all CoWO4/WO3 or CuWO4/WO3 samples exhibit superior photocatalytic performance as compared to pure WO3. This is mainly attributed to the formation of type II heterojunction between WO3 and CoWO4 or CuWO4, which can promote the photogenerated electrons and holes separation and transfer. Moreover, it is found that 0.2% CoWO4/WO3 or 0.2% CuWO4/WO3, in which MWO4 nanoparticles are uniformly dispersed on the surface of WO3, can achieve the most excellent photocatalytic activity among CoWO4/WO3 or CuWO4/WO3 samples, respectively. As compared with WO3, an enhancement about 9.1 times or 6.8 times in photocatalytic activity is observed on 0.2% CoWO4/WO3 or 0.2% CuWO4/WO3, respectively. Furthermore, the active species trapping experiment demonstrates that ·OH, h+, and ·O-2 generated during the photocatalytic process are all the reactive species in photocatalytic degradation of Rhodamine B(RhB) on CoWO4/WO3 or CuWO4/WO3. This study presents a strategy to design superior photocatalyst for organic compound degradation. | He Fang Kang Mingliang Song Chundong Yang Xia Zhang Jing | 2019 | China Petroleum Processing & Petrochemical Technology2019，21，4： | 1 |
| 15 | Single-molecule imaging reveals the stoichiometry change of epidermal growth factor receptor during transactivation by β_2-adrenergic receptor显示文摘Stimulation of G protein-coupled receptors(GPCRs) can lead to the transactivation of the epidermal growth factor receptors(EGFR). The cross-communication between the two signaling pathways regulates several important physiological or pathological processes. However, the molecule mechanism underlying EGFR transactivation remains poorly understood. Here, we aim to study the GPCR-mediated EGFR transactivation process using the single-molecule fluorescence imaging and tracking approach.We found that although EGFR existed as monomers at the plasma membrane of resting cells, they became dimers and thus diffused slower following the activation of β2-adrenergic receptor(β2-AR) by isoproterenol(ISO). We further proved thatβ2-AR-mediated changes of EGFR in stoichiometry and dynamics were mediated by Src kinase. Thus, the observations obtained via the single-molecule imaging and tracking methods shed new insights into the molecular mechanism of EGFR transactivation at single molecule level. | Mingliang Zhang Kangmin He Jimin Wu Nan Li Jinghe Yuan Wei Zhou Zi Ye Zijian Li Han Xiao Zhizhen Lv Youyi Zhang Xiaohong Fang | 2017 | Science China Chemistry2017，60，10： | 1 |
| 16 | Genome-wide identification and expression analysis of NtbHLH gene family in tobacco(Nicotiana tabacum)and the role of NtbHLH86 in drought adaptation显示文摘The bHLH transcription factors play pivotal roles in plant growth and development,production of secondary metabolites and responses to various environmental stresses.Although the bHLH genes have been well studied in model plant species,a comprehensive investigation of the bHLH genes is required for tobacco with newly obtained high-quality genome.In the present study,a total of 309 NtbHLH genes were identified and can be divided into 23 subfamilies.The conserved amino acids which are essential for their function were predicted for the NtbHLH proteins.Moreover,the NtbHLH genes were conserved during evolution through analyzing the gene structures and conserved motifs.A total of 265 NtbHLH genes were localized in the 24 tobacco chromosomes while the remained 44 NtbHLH genes were mapped to the scaffolds due to the complexity of tobacco genome.Moreover,transcripts of NtbHLH genes were obviously tissue-specific expressed from the gene-chip data from 23 tobacco tissues,and expressions of 20 random selected NtbHLH genes were further confirmed by quantitative real-time PCR,indicating their potential functions in the plant growth and development.Importantly,overexpressed NtbHLH86 gene confers improve drought tolerance in tobacco indicating that it might be involved in the regulation of drought stress.Therefore,our findings here provide a valuable information on the characterization of NtbHLH genes and further investigation of their functions in tobacco. | Ge Bai Da-Hai Yang Peijian Chao Heng Yao MingLiang Fei Yihan Zhang Xuejun Chen Bingguang Xiao Feng Li Zhen-Yu Wang Jun Yang He Xie | 2021 | Plant Diversity2021，43，6： | 1 |
| 17 | Nonisothermal crystallization kinetics of polyoxymethylene/montrnorillonite nanocomposite显示文摘 | Xu Weibing Ge Mingliang He Pingsheng | 2001 | J of applied polymer science2001，28，9： | 1 |
| 18 | A complete assembly of the rice Nipponbare reference genome显示文摘Dear Editor,In 2005,the current commonly used rice reference genome(Oryza sativa ssp.japonica cv.Nipponbare)was initially released by the International Rice Genome Sequencing Project(International Rice Genome Sequencing Project,2005).Thereafter,the reference genome was further updated in 2013 with improved genome assembly(IRGSP-1.0)and gene annotations(MSU7,RAP-DB)(Kawahara et al.,2013;Sakai et al.,2013).In the past 10 years,this reference has been serving as one of the most important genetic resources for subsequent rice functional genomics efforts.As several rice genomes had been assembled into gapless chromosomes with only 2–5 telomeres absent(Li et al.,2021;Song et al.,2021;Zhang et al.,2022),the IRGSP1.0 and its annotations still performed as the most widely used reference.However,limitations of sequencing technology and intricate genomic organization led to an under-representation of complex regions in this reference,leaving a total of 72 major gaps(including 19 telomeres),167 minor gaps,and 779 unknown bases(Kawahara et al.,2013),with an estimated length of3%of the genome unsolved. | Lianguang Shang Wenchuang He Tianyi Wang Yingxue Yang Qiang Xu Xianjia Zhao Longbo Yang Hong Zhang Xiaoxia Li Yang Lv Wu Chen Shuo Cao Xianmeng Wang Bin Zhang Xiangpei Liu Xiaoman Yu Huiying He Hua Wei Yue Leng Chuanlin Shi Mingliang Guo Zhipeng Zhang Bintao Zhang Qiaoling Yuan Hongge Qian Xinglan Cao Yan Cui Qianqian Zhang Xiaofan Dai Congcong Liu Longbiao Guo Yongfeng Zhou Xiaoming Zheng Jue Ruan Zhukuan Cheng Weihua Pan Qian Qian | 2023 | Molecular Plant2023，16，8： | 1 |
| 19 | Nonisothermal crystallization kinetics of polypropylene/montmorillonite nanocomposites 显示文摘 | XU Weibing GE Mingliang HE Pingsheng | 2002 | J Polym Sci Part B: Polym Phys2002，40，5： | 1 |
| 20 | Effect of Maotai liquor on P53 gene in primary hepatocellular carcinoma induced by compound factors in rats显示文摘In China,the morbidity of alcoholic liver diseases (ALD)is increasing,which is the second cause of liver diseases after viral hepatitis.An epidemiological survey of 99 subjects in Kweichow Maotai Distillery who have drunk a lot of Maotai liquor for a long time showed that fatty livers were predominate and the incidence of hepatic fibrosis and cirrhosis was relatively low.1 Now,we carried out an animal experiment to investigate the mutation of P53 gene in liver tissues of primary hepatocellular carcinoma (HCC) induced by compound factors. | Zhao Xueke Cheng Mingliang Mu Mao Liu Junling He Chang Zhang Quan | 2014 | Chinese Medical Journal2014，，2： | 1 |
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