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| 1 | Distant eQTLs and Non-coding Sequences Play Critical Roles in Regulating Gene Expression and Quantitative Trait Variation in Maize显示文摘 | Haijun Liu Xin Luo Luyao Niu Yingjie Xiao Lu Chen Jie Liu Xiaqing Wang Minliang Jin Wenqiang Li Qinghua Zhang Jianbing Yan | 2017 | Molecular Plant2017，10，3： | 13 |
| 2 | Hepatitis C virus core protein triggers expansion and activation of CD4+CD25+ regulatory T cells in chronic hepatitis C patients显示文摘 | Naicui Zhai Xiumei Chi Tianyang Li Hongxiao Song Haijun Li Xia Jin Ian Nicholas Crispe Lishan Su Junqi Niu Zhengkun Tu | 2015 | Cellular & Molecular Immunology2015，12，6： | 10 |
| 3 | A new method for computing the uniaxial modulus of articular cartilages using modified inhomogeneous triphasic model显示文摘在结构和关节的软骨的织物作文的微妙的变化能导致它的退化,是众所周知的。现在的纸基于 Narmoneva 等建议的不同类的 triphasic 模型与四个参数提出一个修改分层的不同类的 triphasic 模型。合并一个 piecewise 试穿优化标准,新模型被用来获得单轴的模量哈,并且基于测量超声的胀大种类数据为关节的软骨预言胀大的模式。结果证明新方法能被用来比不同类的 triphasic 模型在单轴的模量上向更多的精确评价提供三个参数和同类的模式,并且有效地预言堕落关节的软骨的高度不一致的分发的胀大的种类。这研究能为探索提供增补信息机械并且软骨的材料性质,并且因此对骨关节炎相关的疾病的诊断有用。关键词关节的软骨 - Triphasic 模型 - 不同类 - 渗透的压力 - Unaxial 模块工程被中国的国家自然科学基础支持(10772018, 30872720 ) 。 | Haijun Niu Qing Wang Yongping Zheng Yubo Fan | 2010 | Acta Mechanica Sinica2010，26，1： | 7 |
| 4 | Relationship between triphasic mechanical properties of articular cartilage and osteoarthritic grade显示文摘The purpose of this study was to explore the triphasic mechanical properties of osteoarthritic cartilage with different pathological grades.First,samples of cartilage from rabbits with different stages of osteoarthritis (OA) were graded.Following this,the cartilage was strained by a swelling experiment,and changes were measured using a high-frequency ultrasound system.The result,together with fixed charge density and water volume fraction of cartilage samples,was used to estimate the uniaxial modulus of the cartilage tissue,based on a triphasic model.For the control cartilage samples,the uniaxial elastic modulus on the cartilage surface was lower than those in the middle and deep layers.With an increase in the OA grade,the uniaxial elastic modulus of the surface,middle and deep layers decreased.A significant difference was found in the surface elastic modulus of different OA grades (P<0.01),while no significant differences were identified for OA cartilages of Grades 1 and 2 in the middle and deep layers (P<0.01).Compared with Grades 1 and 2,there was a significant reduction in the elastic modulus in the middle and deep layers of Grade 3 OA cartilage (P<0.05).Overall,this study may provide a new quantitative method to evaluate the severity of OA using the mechanical properties of cartilage tissue. | NIU HaiJun LIU ChengRui LIAng WANG Qing WANG YueXiang LI DeYu FAN YuBo | 2012 | Science China(Life Sciences)2012，55，5： | 3 |
| 5 | Ultrasound speed and attenuation in progressive trypsin digested articular cartilage显示文摘Subtle changes of articular cartilage(AC) can lead to tissue degeneration and even osteoarthritis(OA).The early degeneration of AC is closely related to a change in proteoglycans(PG) content.The observation of PG is therefore an appropriate way of studying OA and evaluating the degree of AC degeneration.In this study,20 cartilage-bone samples were prepared from normal porcine femoral condyle cartilage and 10 samples were digested over 2 h using 0.25% trypsin solution.The dynamic process of PG-digestion was explored using a conventional A-mode ultrasound(US) experimental system with a 10 MHz center frequency.Quantitative acoustic parameters were calculated from ultrasonic radio-frequency echo signals and included US speed(USS),US amplitude attenuation coefficient(UAA) and broadband US attenuation coefficient(BUA).The experimental results showed that the conventional A-mode ultrasound is valuable for tracking the degree of PG-digestion.Histology also confirmed the validity of the ultrasound observations.For every AC sample,the degree of PG-digestion within a given time was different and was affected by individual differences.After two hours of degeneration,USS showed a mean decrease of 0.4%(P<0.05).UAA was significantly lower after a two-hour PG depletion period(from(2.45±0.23) to(2.28±0.41) dB mm?1).BUA showed no significant differences during this process.In conclusion,conventional ultrasound can provide useful information about trypsin-induced progressive PG depletion in AC and can reflect variations of PG content via the quantitative acoustic parameters USS and UAA.The results of this study may be used to identify an indirect indicator of cartilage matrix integrity and OA disease progression. | NIU HaiJun LI LiFeng SUN Feng YAN Yan WANG YueXiang LI DeYu FAN YuBo | 2011 | Science China(Life Sciences)2011，54，11： | 3 |
| 6 | Effect of microstructure evolution and crystal structure on thermal properties for plasma-sprayed RE_(2)SiO_(5)(RE=Gd,Y,Er)environmental barrier coatings显示文摘In this work,the microstructure evolution,thermal expansion,thermal conductivity,and thermal shock resistance properties of the plasma-sprayed Xl-Gd_(2)SiO_(5),X2-Y_(2)SiO_(5),and X2-Er_(2)SiO_(5)coatings were evaluated and compared by experimental measurement and theoretical exploration.Results showed that significant microstructure evolution such as crystallization of amorphous phase,grain growth,and defects reduction was observed in the RE_(2)SiO_(5)coatings after thermal aging at 1400℃.The Xl-Gd_(2)SiO_(5)coating exhibited higher CTE values than the X2-Y_(2)SiO_(5)and X2-Er_(2)SiO_(5)coatings,which was related to their crystal structure.The thermal conductivity of thermal-aged RE_(2)SiO_(5)coating was much higher than that of the as-sprayed RE_(2)SiO_(5)coating,and thermal conductivity was determined not only by crystal structure but also mainly by the microstructure of the coatings.The X2-Y_(2)SiO_(5)and X2-Er_(2)SiO_(5)coatings with lower thermal mismatch stre s ses presented much better thermal shock resistance than the X1-Gd_(2)SiO_(5)coating. | Xin Zhong Tao Zhu Yaran Niu Haijun Zhou Le Zhang Xiangyu Zhang Qilian Li Xuebin Zheng | 2021 | Journal of Materials Science & Technology2021，，26： | 1 |
| 7 | Enhancement of the efficiency of dye-sensitized solar cell with muki-wall car- bon nanotubes/polythiophene composite counter electrodes prepared by electrodeposition显示文摘 | Luo Jun Niu Haijun Wu Wenjun | 2012 | Solid State Sci2012，14，1： | 1 |
| 8 | The use of lipid-coated nanodiamond to improve bioavailability and efficacy of sorafenib in resisting metastasis of gastric cancer显示文摘 | Zhiwen Zhang Baohua Niu Jian Chen Xinyu He Xiaoyue Bao Jianhua Zhu Haijun Yu Yaping Li | 2014 | Biomaterials2014，，15： | 1 |
| 9 | Positive Effects of Biochar on the Degraded Forest Soil and Tree Growth in China:A Systematic Review显示文摘Soil degradation threatens the forest sustainable productivity,particularly in afforestation system.Biochar derived from agroforestry waste or biomass can potentially improve the degraded forest soil and promote the tree growth.To expand the application of biochar for forestry productivity improvement,we here reviewed the effects and the underlying mechanisms of biochar on the degraded forest soil and tree growth.Totally 96 studies that conducted from pot to field investigations in China were summarized.The result suggested that biochar generally exerted positive effects on restoration of degraded forest soil such as that with compaction,acidification or soil erosion,which are mainly manifested by improving soil porosity,increasing pH,enhancing erosion resistance and mitigating greenhouse gas emissions.Furthermore,biochar incorporation promoted the growth of tested trees in most cases,which effect was mainly attributing to directly supplying nutrients,improving soil physio-chemical properties,enhancing the root’s nutrient absorption capacity,and enlarging the living space.In summary,current studies demonstrate that biochar has a unique potential for improving degraded forest soils and promoting tree growth.However,investigations on the underlying mechanisms and the long-term effects should be strengthened. | Jingkang Zhang Shiyuan Zhang Changhao Niu Jiang Jiang Haijun Sun | 2022 | Phyton-International Journal of Experimental Botany2022，91，8： | 1 |
| 10 | Exponential Stability and Periodic Solutions of FCNNs with Variable Coefficients and Time-varying Delays显示文摘 | Shuyun Niu Haijun Jiang Zhidong Teng | 2008 | Neurocomputing2008，，71： | 1 |
| 11 | The Tianlai Cylinder Pathfinder array: System functions and basic performance analysis显示文摘The Tianlai Cylinder Pathfinder is a radio interferometer array designed to test techniques for 21 cm intensity mapping in the post-reionization Universe,with the ultimate aim of mapping the large scale structure and measuring cosmological parameters such as the dark energy equation of state.Each of its three parallel cylinder reflectors is oriented in the north-south direction,and the array has a large field of view.As the Earth rotates,the northern sky is observed by drift scanning.The array is located in Hongliuxia,a radio-quiet site in Xinjiang,and saw its first light in September 2016.In this first data analysis paper for the Tianlai cylinder array,we discuss the sub-system qualification tests,and present basic system performance obtained from preliminary analysis of the commissioning observations during 2016-2018.We show typical interferometric visibility data,from which we derive the actual beam profile in the east-west direction and the frequency band-pass response.We describe also the calibration process to determine the complex gains for the array elements,either using bright astronomical point sources,or an artificial on site calibrator source,and discuss the instrument response stability,crucial for transit interferometry.Based on this analysis,we find a system temperature of about 90 K,and we also estimate the sensitivity of the array. | JiXia Li ShiFan Zuo FengQuan Wu YouGang Wang JuYong Zhang ShiJie Sun YiDong Xu ZiJie Yu Reza Ansari YiChao Li Albert Stebbins Peter Timbie YanPing Cong JingChao Geng Jie Hao QiZhi Huang JianBin Li Rui Li DongHao Liu YingFeng Liu Tao Liu John PMarriner ChenHui Niu Ue-Li Pen Jeffery BPeterson HuLi Shi Lin Shu YaFang Song HaiJun Tian GuiSong Wang QunXiong Wang RongLi Wang WeiXia Wang Xin Wang KaiFeng Yu Jiao Zhang BoQin Zhu JiaLu Zhu XueLei Chen | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，12： | 0 |
| 12 | A mutli-scale spatial-temporal convolutional neural network with contrastive learning for motor imagery EEG classification显示文摘Motor imagery(MI)based Brain-computer interfaces(BCIs)have a wide range of applications in the stroke rehabilitation field.However,due to the low signal-to-noise ratio and high cross-subject variation of the electroencephalogram(EEG)signals generated by motor imagery,the classification performance of the existing methods still needs to be improved to meet the need of real practice.To overcome this problem,we propose a multi-scale spatial-temporal convolutional neural network called MSCNet.We introduce the contrastive learning into a multi-temporal convolution scale backbone to further improve the robustness and discrimination of embedding vectors.Experimental results of binary classification show that MSCNet outperforms the state-of-theart methods,achieving accuracy improvement of 6.04%,3.98%,and 8.15%on BCIC IV 2a,SMR-BCI,and OpenBMI datasets in subject-dependent manner,respectively.The results show that the contrastive learning method can significantly improve the classification accuracy of motor imagery EEG signals,which provides an important reference for the design of motor imagery classification algorithms. | Ruoqi Zhao Yuwen Wang Xiangxin Cheng Wanlin Zhu Xia Meng Haijun Niu Jian Cheng Tao Liu | 2023 | Medicine in Novel Technology and Devices2023，，1： | 0 |
| 13 | Study of third-order nonlinear susceptibility of polySchiff base containing triphenylamine显示文摘PolySchiff base containing triphenylamine has been synthesized by polycondensation and character-ized by FT-IR,NMR,UV-visible spectrometer. Measurements of the third-order optical nonlinear sus-ceptibility χ(3) by Z-scan technique have shown that the large nonlinearity is dominated by the two-photon absorption in PSB. The sign and size of real part Reχ(3) ,nonlinear refractive index n2 have been measured with the condition of 532 nm,8 ns-duration pulses to be -1.23×10-10 esu,-3.06×10-12 esu;nonlinear absorption index β and size of image part Imχ(3) to be 3.63×10-10 m/W,1.15×10-11 esu,respec-tively,so the third-order nonlinear susceptibility χ(3) is 1.19×10-11 esu. The value is larger than other polymers reported. PSB is self-focusing material and has potential application in nonlinear optic field. | NIU HaiJun WANG Wen HUANG YuDong ZHANG YunDong ZHANG YunJun BAI XuDuo LIU Yuan | 2007 | Science China Chemistry2007，50，2： | 0 |
| 14 | Tolerance and acceptance of hepatic venous pressure gradient measurement in cirrhosis(CHESS1904):An international multicenter study显示文摘Aim:To determine the tolerance and acceptance of hepatic venous pressure gradient(HVPG)measurements in patients with liver cirrhosis.Methods:This prospective international multicenter study included 271 patients with cirrhosis who were scheduled to undergo HVPG measurement between October 2019 and June 2020.Data related to the tolerance and acceptance of HVPG measurements were collected using descriptive questionnaires.Results:HVPG measurements were technically successful in all 271 patients,with 141(52.0%)undergoing HVPG measurement alone.The complication rate was 0.4%.Postoperative pain was significantly lower than preoperative expected pain(p<0.001)and intraoperative pain(p<0.001),and intraoperative pain was also significantly lower than preoperative expected pain(p=0.036).No,mild,moderate,severe,and intolerable discomfort scores were reported by 36.9%,44.6%,11.1%,6.3%,and 0.4%of these patients,respectively,during HVPG measurement and by 54.6%32.5%,11.4%,1.5%,and 0%,respectively,after HVPG measurement.Of these patients,39.5%had little understanding and 10%had no understanding of the value of HVPG measurement,with 35.1%and 4.1%regarding HVPG measurements as being of little or no help,respectively.Most patients reported that they would definitely(15.5%),probably(46.9%),or possibly(29.9%)choose to undergo additional HVPG measurements again,and 62.7%regarded the cost of the procedure as acceptable.Conclusion:HVPG measurement was safe and well‐tolerated in patients with cirrhosis,but patient education and communication are warranted to improve the acceptance of this procedure. | Jun‐Hui Sun He Zhao Haijun Zhang Lei Li NecatiÖrmeci Zi‐Niu Yu Xun Li Shuangxi Li Xujun Yang Huaping Wei Xiaoliang Zhu Zhengcong Zhang Yajin Wang Zhongwei Zhao Jianting Mao Qiaohong Wu Xiaole Sun Huiling Xiang Kefeng Jia Chao Yang Wei Wu Xiuqing Lin Haixin Yao Changzeng Zuo Jitao Wang Bo Zhang Chunqing Zhang Xiaoling Wu Guangchuan Wang Shengjuan Yao Ruihang Wang Li Zhou Hui Huan Qingli Tu Xue Pu Feng Zhang Qin Yin Linpeng Zhang Ying Guo Jian Wang Kohei Kotani Sawako Uchida‐Kobayashi Norifumi Kawada He Zhu Li Li Wei Wang Guo Zhang Lei Yu Xudong Cui Qingliang Zhu Hailong Zhang Xiaoli Hu Rafael OXimenes Adriano Gonçalves de Araújo Giulliano Gardenghi Yubao Zheng Zebin Wu Mingsheng Huang Xiaoyong Chen Jun Wu Feng Xie Yang Bo Shengjuan Hu Linke Ma Xiao Li Xiaolong Qi | 2022 | Portal Hypertension & Cirrhosis2022，1，1： | 0 |
| 15 | Preliminary animal studies on observation of injured spinal cord with intraoperative ultrasound backscatter microscopy显示文摘Many studies have shown that strategies of nerve regeneration and cell-based transplantation are valid based on animal models of spinal cord injury (SCI).To apply these strategies and bridge spinal cord defects,the identification and precise localization of lesions during spinal cord surgery is necessary.The aim of the present experiment was to evaluate the capabilities of ultrasound backscatter microscopy (UBM) in identifying morphologic changes after SCI.After laminectomy,high-resolution ultrasound images of the spinal cord were obtained in one normal and seven spinal cord-injured adult Wistar rats using a UBM system with a 55-MHz center frequency scanner.Comparison between histoanatomic and UBM images was also performed.The results showed that UBM can identify cysts after the experimental SCI is removed in adult rats.In addition,the glial scar formed in secondary injury showed obvious hyperechoic speckle in the UBM image and correlated with the histoanatomic image.UBM has obvious clinical value in nerve regeneration and cell-based transplantation strategies in injured spinal cords. | HaiJun Niu LiFeng Li Kai Liao XiaoGuang Li YuBo Fan | 2012 | Chinese Science Bulletin2012，57，18： | 0 |
| 16 | Therapy Response of Chinese Herbal Medicine in Advanced Liver Cancer: A Retrospective Observational Clinical Trial显示文摘 | Guangmei Lv Liling Zhu Haijun Wan Ping Li Jing Zhang Ruoqu Wei Chongfeng Niu ShengnaiZheng Yongling Gong | 2016 | Journal of Pharmacy and Pharmacology2016，4，3： | 0 |
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