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| 1 | Tri-Co Robot: a Chinese robotic research initiative for enhanced robot interaction capabilities显示文摘Since the invention of the first industrial robot in 1959, the missions of robots have evolved from basic mechanical transfer or assistance to a diverse range of tasks through close interactions with environment, their human counterparts and robot peers. Through adaptation to uncertain and dynamic environments. | Han Ding Xuejun Yang Nanning Zheng Ming Li Yinan Lai Hao Wu | 2018 | National Science Review2018，5，6： | 24 |
| 2 | Agriculture Green Development: a model for China and the world显示文摘Realizing sustainable development has become a global priority.This holds,in particular,for agriculture.Recently,the United Nations launched the Sustainable Development Goals(SDGs),and the Nineteenth National People’s Congress has delivered a national strategy for sustainable development in China—realizing green development.The overall objective of Agriculture Green Development(AGD)is to coordinate'green'with'development'to realize the transformation of current agriculture with high resource consumption and high environmental costs into a green agriculture and countryside with high productivity,high resource use efficiency and low environmental impact.This is a formidable task,requiring joint efforts of government,farmers,industry,educators and researchers.The innovative concept for AGD will focus on reconstructing the whole crop-animal production and food production-consumption system,with the emphasis on high thresholds for environmental standards and food quality as well as enhanced human well-being.This paper addresses the significance,challenges,framework,pathways and potential solutions for realizing AGD in China,and highlights the potential changes that will lead to a more sustainable agriculture in the future.Proposals include interdisciplinary innovations,whole food chain improvement and regional solutions.The implementation of AGD in China will provide important implications for the countries in developmental transition,and contribute to global sustainable development. | Jianbo SHEN Qichao ZHU Xiaoqiang JIAO Hao YING Hongliang WANG Xin WEN Wen XU Tingyu LI Wenfeng CONG Xuejun LIU Yong HOU Zhenling CUI Oene OENEMA William JDAVIES Fusuo ZHANG | 2020 | Frontiers of Agricultural Science and Engineering2020，7，1： | 18 |
| 3 | Using the EMD Method to Determine Fault Criterion for Medium-low Pressure Gas Regulators显示文摘By extracting the outlet pressure data of gas regulators,this paper uses the EMD toolbox of the MATLAB software,which can perform data decomposition and the Hilbert-Huang Transform to find the rules with fault data.Eventually,the medium-low pressure gas regulator fault criterion can be established. | HAO Xuejun LIU Qiang YANG Guobin DU Yi | 2015 | Journal of Thermal Science2015，24，6： | 11 |
| 4 | Division of Matrix- and Fracture-Type Shale Oils in the Jiyang Depression and Their Differences显示文摘This study discussed the division of matrix- and fracture-type shale oils in the Jiyang Depression, and proposed the concept of fracture development coefficient. The fracture development coefficient is defined as the ratio of fault throw to the distance between a shale oil well and the nearest fault. Based on CO_2 content, state of water, oil production and logging response of shale oil formations, the classification of shale oils was established, i.e., a fracture-type shale oil well has a fracture development coefficient greater than 0.2, while a matrix-type one has a fracture development coefficient less than 0.2. Furthermore, the key control factors of matrix- and fracture-type shale oil enrichment were analyzed using typical anatomical and statistical methods. For matrix-type shale oil enrichment, these factors are lithofacies, total organic carbon(TOC), shale porosity and abnormal pressure; for fracture-type shale oil enrichment, they are lithofacies, extent of fracture development, and abnormal pressure. This study also first described the differences between matrix- and fracture-type shale oils. The results provide reference for the exploration of terrestrial faulted basins in eastern China. | NING Fangxing WANG Xuejun HAO Xuefeng ZHU Deyan ZHU Deshun | 2015 | Acta Geologica Sinica(English Edition)2015，89，6： | 7 |
| 5 | First light of the 1.8-m solar telescope–CLST显示文摘Large-aperture solar telescopes play an important role in solar observations and research,and require high temporal and spatial resolution[1].To solve some fundamental problems such as the solar dynamo,coronal heating,and the triggering of major solar eruptions,the spatial resolution for solar-atmosphere observation should reach at least 0.1 arcsec[2]. | ChangHui Rao NaiTing Gu XueJun Rao Cheng Li LanQiang Zhang JinLong Huang Lin Kong Ming Zhang YunTao Cheng Yi Pu Hua Bao YouMing Guo YangYi Liu JinSheng Yang LiBo Zhong ChangJun Wang Kai Fang XiaoJun Zhang DongHong Chen Cheng Wang XinLong Fan ZhiWu Yan KeLe Chen XiYa Wei Lei Zhu Hong Liu YongJian Wan Hao Xian WenLi Ma | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，10： | 6 |
| 6 | Atmospheric deposition of inorganic nitrogen in a semi-arid grassland of Inner Mongolia, China显示文摘Due to increasing global demand for crop production and energy use, more and more reactive nitrogen(Nr) has been generated and emitted to the environment. As a result, global atmospheric nitrogen(N) deposition has tripled since the industrial revolution and the ecological environment and human health have been harmed. In this study, we measured dry and wet/bulk N deposition from July 2013 to December 2015 in a semi-arid grassland of Duolun County, Inner Mongolia, China. The samples of dry and wet/bulk N deposition were collected monthly with a DELTA(DEnuder for Long Term Atmospheric sampling) system and with Gradko passive samplers and a precipitation gauge. The measured results show that the annual mean concentrations of NH_3, NO_2, HNO_3, particulate NH_4^+(pNH_4^+) and particulate NO_3^-(pNO_3^-) in atmosphere were 2.33, 1.90, 0.18, 1.42 and 0.42 μg N/m3, respectively, and that the annual mean volume-weighted concentrations of NH_4^+-N and NO_3^--N in precipitation were 2.71 and 1.99 mg N/L, respectively. The concentrations of Nr components(including NH_3, NO_2, HNO_3, p NH_4^+, pNO_3^-, NH_4^+-N and NO_3^--N) exhibited different seasonal variations. Specifically, NO_2 and HNO_3 exhibited higher concentrations in autumn than in summer, while the other Nr components(NH_3, pNH_4^+, pNO_3^-, NH_4^+-N and NO_3^--N) showed the highest values in summer. Based on measured concentrations of Nr components and their deposition velocities estimated using the GEOS-Chem global atmospheric chemical transport model, the calculated annual mean dry deposition fluxes were 3.17, 1.13, 0.63, 0.91 and 0.36 kg N/(hm^2·a) for NH_3, NO_2, HNO_3, p NH_4^+ and pNO_3^-, respectively, and the calculated annual mean wet/bulk deposition fluxes were 5.37 and 3.15 kg N/(hm^2·a) for NH_4^+-N and NO_3^--N, respectively. The estimated annual N deposition(including dry N deposition and wet/bulk N deposition) reached 14.7 kg N/(hm^2·a) in grassland of Duolun County, approaching to the upper limit of the N critical load(10–15 kg N/(hm^2·a)). Dry and wet/bulk deposition fluxes of all Nr components(with an exception of HNO_3) showed similar seasonal variations with the maximum deposition flux in summer and the minimum in winter. Reduced Nr components(e.g., gaseous NH_3 and p NH_4^+ in atmosphere and NH_4^+-N in precipitation) dominated the total N deposition at the sampling site(accounted for 64% of the total N deposition), suggesting that the deposited atmospheric Nr mainly originated from agricultural activities. Considering the projected future increases in crop and livestock production in Inner Mongolia, the ecological and human risks to the negative effects of increased N deposition could be increased if no mitigation measures are taken. | ZHANG Yibo XU Wen WEN Zhang WANG Dandan HAO Tianxiang TANG Aohan LIU Xuejun | 2017 | Journal of Arid Land2017，9，6： | 5 |
| 7 | Application of a Support Vector Machine Algorithm to the Safety Precaution Technique of Medium-low Pressure Gas Regulators显示文摘In the gas pipeline system, safe operation of a gas regulator determines the stability of the fuel gas supply, and the medium-low pressure gas regulator of the safety precaution system is not perfect at the present stage in the Beijing Gas Group; therefore, safety precaution technique optimization has important social and economic significance. In this paper, according to the running status of the medium-low pressure gas regulator in the SCADA system, a new method for gas regulator safety precaution based on the support vector machine(SVM) is presented. This method takes the gas regulator outlet pressure data as input variables of the SVM model, the fault categories and degree as output variables, which will effectively enhance the precaution accuracy as well as save significant manpower and material resources. | HAO Xuejun AN Xaioran WU BO HE Shaoping | 2018 | Journal of Thermal Science2018，27，1： | 5 |
| 8 | Phase Ⅱ open-label study of recombinant circularly permuted TRAIL as a single-agent treatment for relapsed or refractory multiple myeloma显示文摘Background: Despite the recent development of new therapies, multiple myeloma(MM) remains an incurable disease. Thus, new, efective treatments are urgently needed, particularly for relapsed or refractory MM(RRMM). In an earlier phase I study, a novel form of recombinant human Apo2L/tumor necrosis factor-related apoptosis-inducing ligand(TRAIL) that is currently in clinical development for the treatment of hematologic malignancies, i.e., circularly permuted TRAIL(CPT), was well tolerated at a dose of 2.5 mg/kg per day and showed promising preliminary activity in patients with RRMM. This phase II, open-label, multicenter study further investigated the eicacy and safety of 2.5-mg/kg per day CPT as single-agent therapy for patients with RRMM.Methods: Patients with RRMM were treated once daily with CPT(2.5 mg/kg, intravenously) for 14 consecutive days for each 21-day cycle. Clinical response and toxicity were assessed after each treatment cycle.Results: Twenty-seven patients received CPT. Using the European Group for Blood and Marrow Transplantation criteria, we calculated the overall response rate of 33.3% with 1 near-complete response(n CR) and 8 partial responses(PRs). The clinical beneit rate(48.1%) included 1 nCR, 8 PRs, and 4 minimal responses. The most common treatmentrelated adverse events(TRAEs) were fever, aspartate aminotransferase elevation, alanine aminotransferase elevation, leucopenia, rash, neutropenia, and thrombocytopenia. We graded toxicity using the Common Toxicity Criteria for Adverse Events, version 3.0, and determined that 37.0% of patients had at least 1 grade 3–4 TRAE.Conclusions: CPT as a single agent can elicit a response in patients with RRMM and is well tolerated. Further clinical investigation is warranted. | Yun Leng Lugui Qiu Jian Hou Yaozhong Zhao Xuejun Zhang Shifang Yang Hao Xi Zhongxia Huang Ling Pan Wenming Chen | 2016 | Chinese Journal of Cancer2016，35，12： | 4 |
| 9 | Research on Online Safety Precaution Technology of a High-medium Pressure Gas Regulator显示文摘In view of some of the characteristics of a high-medium pressure gas regulator, such as small fault samples, many fault types and complex fault features etc, in order to improve the accuracy of fault precaution in this paper, a fault diagnosis method based on the combination of the improved wavelet packet and pressure harmonic distortion rate is proposed. On the basis of the harmonic distortion rate of the outlet pressure and the energy value of each frequency band obtained by improved wavelet packet decomposition, the rules for fault data were summarized. Finally, a safety precaution model of the high-medium pressure gas regulator is established. | HAO Xuejun LIU Xuhai LI Xiaxi ZHAO Xin | 2017 | Journal of Thermal Science2017，26，3： | 2 |
| 10 | A NEW APPROACH TO HOLISTIC NITROGEN MANAGEMENT IN CHINA显示文摘Since the 1980s,the widespread use of N fertilizer has not only resulted in a strong increase in agricultural productivity but also caused a number of environmental problems,induced by excess reactive N emissions.A range of approaches to improve N management for increased agricultural production together with reduced environmental impacts has been proposed.The 4R principles(right product,right amount,right time and right place)for N fertilizer application have been essential for improving crop productivity and N use efficiency while reducing N losses.For example,site-specific N management(as part of 4R practice)reduced N fertilizer use by 32%and increased yield by 5%in China.However,it has not been enough to overcome the challenge of producing more food with reduced impact on the environment and health.This paper proposes a new framework of food-chainnitrogen-management(FCNM).This involves good N management including the recycling of organic manures,optimized crop and animal production and improved human diets,with the aim of maximizing resource use efficiency and minimizing environmental emissions.FCNM could meet future challenges for food demand,resource sustainability and environmental safety,key issues for green agricultural transformation in China and other countries. | Xuejun LIU Zhenling CUI Tianxiang HAO Lixing YUAN Ying ZHANG Baojing GU Wen XU Hao YING Weifeng ZHANG Tingyu LI Xiaoyuan YAN Keith GOULDING David KANTER Robert HOWARTH Carly STEVENS Jagdish LADHA Qianqian LI Lei LIU Wim DE VRIES Fusuo ZHANG | 2022 | Frontiers of Agricultural Science and Engineering2022，9，3： | 2 |
| 11 | Geometrydependent lighting显示文摘 | Chang Ha Lee Xuejun Hao Amitabh Varshney | | 0，，02： | 1 |
| 12 | Subungual exostosis of the finger in an 8-year-old girl显示文摘Introduction:Subungual exostosis(SE)is a relatively uncommon benign bone tumor that occurs in the distal phalanges of the toes or fingers.Case presentation:An 8-year-old girl presented for treatment of an acquired mass on the distal right index finger.The patient was preoperatively diagnosed with a benign bone tumor.Surgical resection of the distal right index finger mass was performed under general anesthesia,and histological examination of the resected tissue supported a diagnosis of SE of the right index finger.The surgical outcome was good,with no surgical site infection.Throughout 15 months of follow-up,the patient was asymptomatic with no recurrence.Conclusion:Surgical resection of a mass on the distal right index finger resulted in absence of recurrence during 15 months of follow-up.SE is a benign and uncommon lesion that is infrequently encountered by physicians.This infrequent occurrence may result in delays in diagnosis and treatment.Complete excision of the lesion and careful separation from underlying nail bed structures results in total resolution of the lesion,while providing the lowest risk of recurrence. | Hao Li Xinyu Qi Xuejun Zhang | 2020 | Pediatric Investigation2020，4，4： | 1 |
| 13 | Simulation Analysis of Factors Influencing Chiller EER显示文摘This study constructed a mathematic model of a variable frequency centrifugal chiller using Simulink software. By running the simulation, it was discovered that when the other factors are constant, the EER(Energy Efficiency Ratio) of the chiller increases with decreases in the temperature of the cooling water and increases in the temperature of the chilled water. The effect of changes in the cooling water temperature on the EER of the chiller is stronger than that of changes in the chilled water temperature. In addition, as the chiller load decreases, the EER increases until reaching a maximum, after which it decreases. Furthermore, the EER of chillers working under a constant flow rate is slightly higher than that of those working under varying flow rates. | HAO Xuejun WANG Tong | 2014 | Journal of Thermal Science2014，23，3： | 1 |
| 14 | Functional characterization of a special thermophilic multifunctional amylase OPMA-N and its N-terminal domain显示文摘编码特殊 thermophilic 的基因多功能的淀粉酶 OPMA-N 从杆菌 sp 被克隆。ZW2531-1。OPMA-N 与典型淀粉酶相比有一个另外的 124 残余 N 终端领域并且与一张 -pleated 表和随机的卷结构形成一个相对独立的领域。这里,我们在 OPMA-N 的功能和性质上报导了不平常的底层和 OPMA-N 的产品特性和另外的 N 终端领域(1124 aa ) 的影响。OPMA-N (12.82 U/mg ) 和它的 N 终端截断域的 OPMA-N (12.55 U/mg ) 仅仅降级了包括麦芽糖, maltotriose, isomaltotriose,和 isomaltotetraose 生产 oligosaccharides,然而并非生产葡萄糖的淀粉。因此, N 终端领域没决定它被它的 C 终端 -pleated 表结构可能调整的底层和产品特性。然而, OPMA-N 的 N 终端领域似乎调制它的催化特征,导致更多的 isomaltotriose 和更少的麦芽糖的生产,并且自从 OPMA-N 从 40 ~ 80 在一个温度范围比 OPMA-N 显示出更高的活动,它似乎贡献 OPMA-N 的 | Fan Li Xuejun Zhu Yanfei Li Hao Cao Yingjiu Zhang | 2011 | Acta Biochimica et Biophysica Sinica2011，43，4： | 1 |
| 15 | Characterization of secondary organic aerosol particles using aerosol laser time-of-flight mass spectrometer coupled with FCM clustering algorithm显示文摘 | Mingqiang Huang Liqing Hao Xiaoyong Guo Changjin Hu Xuejun Gu Weixiong Zhao Zhenya Wang Li Fang Weijun Zhang | 2013 | Atmospheric Environment2013，，： | 1 |
| 16 | Etoposide,dexamethasone,and pegaspargase with sandwiched radiotherapy in early-stage natural killer/T-cell lymphoma:A randomized phase III study显示文摘Methotrexate,etoposide,dexamethasone,and pegaspargase(MESA)with sandwiched radiotherapy is known to be effective for early-stage extranodal natural killer/T-cell lymphoma,nasal type(NKTCL).We explored the efficacy and safety of reduced-intensity,non-intravenous etoposide,dexamethasone,and pegaspargase(ESA)with sandwiched radiotherapy.This multicenter,randomized,phase III trial enrolled patients aged between 14 and 70 years with newly diagnosed early-stage nasal NKTCL from 27 centers in China.Patients were randomly assigned(1:1)to receive ESA(pegaspargase 2,500 IU/m^(2)intramuscularly on day 1,etoposide 200 mg orally,and dexamethasone 40 mg orally on days 2–4)or MESA(methotrexate 1 g/m^(2)intravenously on day 1,etoposide 200 mg orally,and dexamethasone 40 mg orally on days 2–4,and pegaspargase 2,500 IU/m^(2)intramuscularly on day 5)regimen(four cycles),combined with sandwiched radiotherapy. | Huijuan Zhong Shu Cheng Xi Zhang Bing Xu Jiayi Chen Xufeng Jiang Jie Xiong Yu Hu Guohui Cui Juying Wei Wenbin Qian Xiaobing Huang Ming Hou Feng Yan Xin Wang Yongping Song Jianda Hu Yuanhua Liu Xuejun Ma Fei Li Chongyang Wu Junmin Chen Li Yu Ou Bai Jingyan Xu Zunmin Zhu Li Liu Xin Zhou Li Huang Yin Tong Ting Niu Depei Wu Hao Zhang Chaofu Wang Binshen Ouyang Hongmei Yi Qi Song Gang Cai Biao Li Jia Liu Zhifeng Li Rong Xiao Luqun Wang Yujie Jiang Yanyan Liu Xiaoyun Zheng Pengpeng Xu Hengye Huang Li Wang Saijuan Chen Weili Zhao | 2023 | The Innovation2023，4，3： | 0 |
| 17 | microRNA-770 regulates proliferation in glioma through CDK8 mediated signaling pathway显示文摘microRNAs(miRNAs)play crucial roles in tumorigenesis and tumor progression.miR-770 has been reported to be downregulated in several cancers and it affects cancer cell proliferation,apoptosis,metastasis and drug resistance.However,the role and underlying molecular mechanism of miR-770 in human glioma remain unknown.Expressions of miR 770 in glioma tissues and cell lines were measured by quantitative real-time PCR(qRT-PCR)to explore the association of miR-770 expression and clinicopathological characteristics.The expression of CDK8 was detected by qRT-PCR and Western blot in glioma tissues.Target prediction program(RegRNA)and dual-luciferase reporter assay were:conducted to confirm the target gene CDK8 of miR-770.MTT and cell counting assays were used to assess the effect of miR-770 on glioma cell proliferation.The cell cycle distribution and apoptosis were examined by flow cytometry.CDK8 siRNA and overexpression were used to further confirm the function of the target gene. | Zhang Junfeng Xu Hao Shi Lili Zhang Li Zhao Zhaohua Pang Long Chai Xuejun Qi Cunfang Xu Xi | 2021 | 解剖学杂志2021，44，S01： | 0 |
| 18 | An improved inverse PCR protocol for the generation of T-vectors显示文摘 | Xuejun Chen Hao Zhangt Yanfang Zhang Wenyu Cui Chaoliang Long Xiang Jia Hai Wang | 2015 | Acta Biochimica et Biophysica Sinica2015，47，2： | 0 |
| 19 | Effects of Three Drugs on Membrane Metabolism Against Cysticerci cellulosae in vitro显示文摘To investigate the effects and mechanisms of the benzimidazole carbamate and benmidine drugs on Cysticerci cellulosae and choose effective drugs on Cysticerci cellulosae,the membrane metabolism of Cysticerci cellulosae in vitro was tested after three kinds of drugs which were used respectively. The indexes included the contents of lipids,the contents of SA and the changes of the membrane fluidity. The results showed that oxfendazole could inhibit the membrane metabolism of immature and mature Cysticerci cellulosae in vitro,and albendazole only inhibited the mature one,while thibendimidine neither acted on the immature nor mature one. | HAO Yanhong LI Qingzhang GAO Xuejun LIU Yongjie GAO Wenxue | 2009 | Journal of Northeast Agricultural University(English Edition)2009，16，3： | 0 |
| 20 | Activation of NRF2 by celastrol increases antioxidant functions and prevents the progression of osteoarthritis in mice显示文摘Excessive oxidative stress impairs cartilage matrix metabolism balance,significantly contributing to osteoarthritis(OA)development.Celastrol(CSL),a drug derived from Tripterygium wilfordii,has recognized applications in the treatment of cancer and immune system disorders,yet its antioxidative stress mechanisms in OA remain underexplored.This study aimed to substantiate CSL’s chondroprotective effects and unravel its underlying mechanisms.We investigated CSL’s impact on chondrocytes under both normal and inflammatory conditions.In vitro,CSL mitigated interleukin(IL)-1β-induced activation of proteinases and promoted cartilage extracellular matrix(ECM)synthesis.In vivo,intra-articular injection of CSL ameliorated cartilage degeneration and mitigated subchondral bone lesions in OA mice.Mechanistically,it was found that inhibiting nuclear factor erythroid 2-related factor 2(NRF2)abrogated CSL-mediated antioxidative functions and exacerbated the progression of OA.This study is the first to elucidate the role of CSL in the treatment of OA through the activation of NRF2,offering a novel therapeutic avenue for arthritis therapy. | LIU Mingming GUO Jiatian ZHAO Jing LI Hongye FENG Xiaoxiao LIU Haojun ZHANG Hao JIA Xuejun WEI Rushuai LI Fang CHEN Chong HOU Mingzhuang LV Nanning XU Haiyan | 2024 | Chinese Journal of Natural Medicines2024，22，2： | 0 |
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