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3篇 您的检索式:作者名="Gerald Bangura"
    题名 作者 年代 出处 被引量
1中塞友好生物安全实验室埃博拉病毒核酸检测质量控制体系的建立显示文摘详细地阐述了中塞友好生物安全实验室实施埃博拉病毒核酸检测整个质量控制的过程,全面地展示固定P3实验室第一批检测队在埃博拉病毒病实验室检测中表现出的科学、严谨、准确与高效,为实验室检测工作提供参考和依据。首先描述了质控体系要点,包括了组织和人员管理、质量管理文件体系、仪器设备、检测试剂和耗材、审核、实验室空间和功能、实验室维护与安全保障等各个方面的质控要点。其次,从埃博拉病毒核酸检测前、检测中到检测后过程,分述了质控在埃博拉病毒检测整个流程的各个环节中的应用。技术精良的专业检测队伍和实行人性化管理是援非抗埃成功的基石;做好生物安全防护是有效质控和完成检测任务的前提;配备专业的后勤保障确实非常必要;中塞友好生物安全实验室的建立对于中塞友谊具有划时代的意义,该实验室将成为塞拉利昂今后最为重要的埃博拉病毒实验室检测基地。王芹 张勇 聂凯 王环宇 杜海军 宋敬东 肖康 雷雯雯 郭建强 隗合江 蔡琨 王衍海 吴江 Gerald Bangura Idrissa Laybohr Kamara 梁米芳 武桂珍 董小平 2016病毒学报2016,32,2:5
2Serological Investigation of Laboratory-Confirmed and Suspected Ebola Virus Disease Patients During the Late Phase of the Ebola Outbreak in Sierra Leone显示文摘This study aimed to investigate the serological characteristics of Ebola virus(EBOV) infection during the late phase of the Ebola outbreak in Sierra Leone. In total, 877 blood samples from 694 suspected Ebola virus disease(EVD) cases assessed from March to December 2015, were analyzed via real-time reverse transcription polymerase chain reaction(RT-PCR) for viral RNA and enzyme-linked immunosorbent assay(ELISA) and Luminex to detect antibodies against EBOV. Viral load and EBOV-specific IgM/IgG titers displayed a declining trend during March to December 2015. Viral RNA load decreased rapidly at earlier stages after disease onset, while EBOV-specific IgM and IgG still persisted in 58.1%(18/31) and 93.5%(29/31) of the confirmed EVD patients and in 3.8%(25/663) and 17.8%(118/663) of the RNA-negative suspected patients in the later phase, respectively. Dynamic analysis of longitudinally collected samples from eight EVD patients revealed typically reversed trends of declining viral load and increasing IgM and/or IgG titers in response to the EBOV infection.The present results indicate that certain populations of Sierra Leone developed immunity to an EBOV infection in the late phase of the outbreak, providing novel insights into the risk assessment of EBOV infections among human populations.Yang Liu YuLan Sun Wei Wu AQian Li XianDa Yang Shuo Zhang Chuan Li QiuDong Su ShaoJian Cai DaPeng Sun HaiYang Hu Zhe Zhang XiuXu Yang Idrissa Kamara Sheku Koroma Gerald Bangura Alie Tia Abdul Kamara Matt Lebby Brima Kargbo Jiandong Li Shiwen Wang XiaoPing Dong YueLong Shu WenBo Xu George F. Gao GuiZhen Wu DeXin Li William J. Liu MiFang Liang 2018Virologica Sinica2018,33,4:2
3Detection and Analysis of Ebola Virus in Sierra Leone-China Friendship Biosafety Laboratory from March 11 to April 20, 2015显示文摘Ebola virus disease reemerged in Western Africa in 2014.Chinese Center for Disease Control and Prevention dispatched the first Ebola virus(EBOV)detection team to run newly established Sierra Leone-China Friendship Biological Safety Laboratory.The aims of study were to understand epidemiology,clinical manifestations and survival time of EBOV in patient’s blood.A total of 913specimens were tested between March 11 andWANG Qin ZHANG Yong WANG Huan Yu DU Hai Jun NIE Kai SONG Jing Dong XIAO Kang LEI Wen Wen GUO Jian Qiang WEI He Jiang CAI Kun WANG Yan Hai WU Jiang Gerald BANGURA Idrissa Laybohr KAMARA DONG Xiao Ping 2016Biomedical and Environmental Sciences2016,29,6:2
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