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| 1 | Incidence and mortality of stomach cancer in China,2014显示文摘Objective: In this study,we aimed to estimate the updated incidence and mortality rate of stomach cancer based on the cancer registration data in 2014,collected by the National Central Cancer Registry of China(NCCRC).Methods: In 2017,339 registries' data were qualified based on the criteria of data quality control of the NCCRC.Cases of stomach cancer were retrieved from the national database.We estimated numbers of stomach cancer cases and deaths in China using age-specific rates and corresponding national population stratified by area,sex,agegroup(0,1–4,5–9,10–14,…,85+).Chinese standard population in 2000 and Segi's world population were applied for age-standardized incidence and mortality rates.Results: In 2014,410,400 new stomach cancer cases and 293,800 cancer-associated deaths were estimated to have occurred in China.The crude incidence rate of stomach cancer was 30.00/100,000,age-standardized incidence rates by Chinese standard population(ASIRC) and by world standard population(ASIRW) were 19.62/100,000 and19.51/100,000,respectively.The crude mortality rate of stomach cancer was 21.48/100,000,age-standardized mortality rates by Chinese(ASMRC) and by world standard population(ASMRW) were 13.44/100,000 and13.30/100,000,respectively.Incidence and mortality rates in rural areas were both higher than that in urban areas.Stomach cancer has a strong relationship with gender and age.The disease has occurred more frequently among men than women with a male to female ratio of 2.4 for ASIRC.After age group of 40-44 years,incidence rates are substantially higher in men than in women,same pattern was seen for age-specific mortality rates.Conclusions: There is still a heavy burden of stomach cancer in China.The incidence and mortality patterns of stomach cancer show substantial gender and regional disparities.Great effort is needed to provide more accessible health services,sufficient financial resources,and adequate cancer-care infrastructure for the Chinese population,especially for people living in rural areas. | Lei Yang Rongshou Zheng Ning Wang Yannan Yuan Shuo Liu Huichao Li Siwei Zhang Hongmei Zeng Wanqing Chen | 2018 | Chinese Journal of Cancer Research2018，30，3： | 114 |
| 2 | Zircon SHRIMP Dating for the Weiya Pluton, Eastern Tianshan: Its Geological Implications显示文摘The timing of the emplacement of the Weiya pluton remains controversial due to the absence of systematic and precise dating. This paper reports zircon SHRIMP U-Pb dating of different lithologic phases in the Weiya pluton, and discusses the genesis and tectonic environment. The ages of gabbro, quartz syenite, diorite porphyrite and fine-grained granite are 236?6 Ma, 246?6 Ma, 233?8 Ma and 237?8 Ma, respectively. All these phases were formed in early-middle Indosinian (Triassic) in a post-orogenic environment. In addition to underplating, intraplating of mantle-derived magmas is also a substantial mechanism for magma generation and vertical accretion of the continental crust. Granitoid rocks are important products of vertical continental accretion as underplating evolves gradually to intraplating. The existence of post-orogenic Indosinian granites shows that the middle Tianshan orogenic belt underwent an important tectonic conversion from the Paleo-Asian ocean subduction-collision system to the Paleo-Tethys ocean regime. | ZHANG Zunzhong GU Lianxing WU Changzhi LI Weiqiang XI Aihua WANG Shuo | 2005 | Acta Geologica Sinica(English Edition)2005，79，4： | 53 |
| 3 | Gastric cancer: Epidemiology, risk factors and prevention strategies显示文摘Gastric cancer(GC) is a global health problem, with more than 1 million people newly diagnosed with GC worldwide each year. GC is more prevalent in less developed countries than in more developed countries. About half of all GC cases worldwide occur in East Asia, notably China. Globally, overall incidence rates of GC are declining, which is potentially attributed to a decrease in Helicobacter pylori(H. pylori) infection and the use of refrigeration to preserve foods rather than salt. GC is a multifactorial disease, and its occurrence and development were impacted by environmental and genetic factors. H. pylori infection is the primary risk factor for GC, especially for non-cardia. The prognosis of GC is poor due to stages at the first diagnosis. The 5-year survival rate is less than 10% when patients are diagnosed at an advanced stage, but the rate is as high as 85% if patients are detected at an earlier stage. Endoscopic screening can potentially prevent GC by early diagnosis and early treatment and has been widely adopted in screening programs in East Asian countries, such as Japan and Korea. This review summarizes updated epidemiological aspects, risk factors, and prevention strategies of GC in recent years to help researchers determine the most effective intervention strategies for reducing risk of GC. | Lei Yang Xiangji Ying Shuo Liu Guoqing Lyu Zekuan Xu Xi Zhang Huichao Li Qingyu Li Ning Wang Jiafu Ji | 2020 | Chinese Journal of Cancer Research2020，32，6： | 52 |
| 4 | Anisotropic coding metamaterials and their powerful manipulation of differently polarized terahertz waves显示文摘Metamaterials based on effective media can be used to produce a number of unusual physical properties(for example,negative refraction and invisibility cloaking)because they can be tailored with effective medium parameters that do not occur in nature.Recently,the use of coding metamaterials has been suggested for the control of electromagnetic waves through the design of coding sequences using digital elements‘0’and‘1,'which possess opposite phase responses.Here we propose the concept of an anisotropic coding metamaterial in which the coding behaviors in different directions are dependent on the polarization status of the electromagnetic waves.We experimentally demonstrate an ultrathin and flexible polarization-controlled anisotropic coding metasurface that functions in the terahertz regime using specially designed coding elements.By encoding the elements with elaborately designed coding sequences(both 1-bit and 2-bit sequences),the x-and y-polarized waves can be anomalously reflected or independently diffused in three dimensions.The simulated far-field scattering patterns and near-field distributions are presented to illustrate the dual-functional performance of the encoded metasurface,and the results are consistent with the measured results.We further demonstrate the ability of the anisotropic coding metasurfaces to generate a beam splitter and realize simultaneous anomalous reflections and polarization conversions,thus providing powerful control of differently polarized electromagnetic waves.The proposed method enables versatile beam behaviors under orthogonal polarizations using a single metasurface and has the potential for use in the development of interesting terahertz devices. | Shuo Liu Tie Jun Cui Quan Xu Di Bao Liangliang Du Xiang Wan Wen Xuan Tang Chunmei Ouyang Xiao Yang Zhou Hao Yuan Hui Feng Ma Wei Xiang Jiang Jiaguang Han Weili Zhang Qiang Cheng | 2016 | Light(Science & Applications)2016，5，1： | 36 |
| 5 | Exotic origin of the Chinese continental shelf: new insights into the tectonic evolution of the western Pacific and eastern China since the Mesozoic显示文摘The effect of paleo-Pacific subduction on the geological evolution of the western Pacific and continental China is likely complex. Nevertheless, our analysis of the distribution of Mesozoic granitoids in the eastern continental China in space and time has led us to an interesting conclusion: The basement of the continental shelf beneath East and South China Seas may actually be of exotic origin geologically unrelated to the continental lithosphere of eastern China. By accepting the notion that the Jurassic–Cretaceous granitoids in the region are genetically associated with western Pacific subduction and the concept that subduction may cease to continue only if the trench is being jammed, then the termination of the granitoidmagmatism throughout the vast region at *88 ± 2 Ma manifests the likelihood of ‘‘sudden'', or shortly beforehand(*100 Ma), trench jam of the Mesozoic western Pacific subduction. Trench jam happens if the incoming‘‘plate'' or portion of the plate contains a sizeable mass that is too buoyant to subduct. The best candidate for such a buoyant and unsubductable mass is either an oceanic plateau or a micro-continent. We hypothesize that the basement of the Chinese continental shelf represents such an exotic, buoyant and unsubductable mass, rather than seaward extension of the continental lithosphere of eastern China. The locus of the jammed trench(i.e., the suture) is predictably located on the shelf in the vicinity of, and parallel to, the arc-curved coastal line of the southeast continental China. It is not straightforward to locate the locus in the northern section of the East China Sea shelf because of the more recent(\20 Ma) tectonic re-organization associated with the opening of the Sea of Japan. We predict that the trench jam at *100 Ma led to the re-orientation of the Pacific plate motion in the course of NNW direction as inferred from the age-progressive Emperor Seamount Chain of Hawaiian hotspot origin(its oldest unsubdued Meiji and Detroit seamounts are *82 Ma),making the boundary between the Pacific plate and the newly accreted plate of eastern Asia a transform fault at the location east of the continental shelf of exotic origin. This explains the apparent *40 Myr magmatic gap from *88to *50 Ma prior to present-day western Pacific subduction initiation. We propose that basement penetration drilling on well-chosen sites is needed to test the hypothesis in order to reveal the true nature of the Chinese continental shelf basement. This testing becomes critical and cannot longer be neglected in order to genuinely understand the tectonic evolution of the western Pacific and its effect on the geology of eastern China since the Mesozoic, includingthe cratonic lithosphere thinning, related magmatism/mineralization, and the mechanism of the subsequent South China Sea opening, while also offering novel perspectives on aspects of the plate tectonics theory. We also suggest the importance of future plate tectonic reconstruction of the western Pacific to consider the nature and histories of the Chinese continental shelf of exotic origin as well as the probable transform plate boundary from *100 to*50 Ma. Effort is needed to reveal the true nature and origin of the *88 ± 2 Ma granitic gneisses in Taiwan and the 110–88 Ma granitoids on the Hainan Island. | Yaoling Niu Yi Liu Qiqi Xue Fengli Shao Shuo Chen Meng Duan Pengyuan Guo Hongmei Gong Yan Hu Zhenxing Hu Juanjuan Kong Jiyong Li Jinju Liu Pu Sun Wenli Sun Lei Ye Yuanyuan Xiao Yu Zhang | 2015 | Science Bulletin2015，60，18： | 32 |
| 6 | Effectiveness of acupuncture to treat irritable bowel syndrome: A meta-analysis显示文摘AIM:To evaluate the efficacy of acupuncture for treatment of irritable bowel syndrome(IBS)through metaanalysis of randomized controlled trials.METHODS:We searched MEDLIINE,PubMed,Scopus,Web of Science,and Cochrane Central Register of Controlled Trials from 1966 to February 2013 for doubleblind,placebo-controlled trials investigating the efficacy of acupuncture in the management of IBS.Studies were screened for inclusion based on randomization,controls,and measurable outcomes reported.We used the modified Jadad score for assessing the quality of the articles.STATA 11.0 and Revman 5.0 were used for meta-analysis.Publication bias was assessed by Begg’s and Egger’s tests.RESULTS:Six randomized,placebo-controlled clinical trials met the criteria and were included in the metaanalysis.The modified Jadad score of the articles was>3,and five articles were of high quality.We analyzed the heterogeneity and found that these studies did not cause heterogeneity in our meta-analysis.Begg’s test showed P=0.707 and Egger’s test showed P=0.334.There was no publication bias in our meta-analysis(Begg’s test,P=0.707;Egger’s test,P=0.334).From the forest plot,the diamond was on the right side of the vertical line and did not intersect with the line.The pooled relative risk for clinical improvement with acupuncture was 1.75(95%CI:1.24-2.46,P=0.001).Using the two different systems of STATA 11.0 and Revman 5.0,we confirmed the significant efficacy of acupuncture for treating IBS.CONCLUSION:Acupuncture exhibits clinically and statistically significant control of IBS symptoms. | Guan-Qun Chao Shuo Zhang | 2014 | World Journal of Gastroenterology2014，20，7： | 33 |
| 7 | A Survey of 16 Rare Earth Elements in the Major Foods in China显示文摘Objective The aim of this survey was to inves gate the level of contamina on of the most consumed foods in China with 16 rare earth elements (REEs),and to provide the basic data for establishing and revising food safety standards for REEs.Methods Sixteen REEs in foods were measured by induc vely coupled plasma-mass spectrometry (ICP-MS) in the labs of the Centers for Disease Control and Preven on of four provinces and two municipali es,during 2009-2010.Results 1 231 samples were analyzed and 19 121 concentra on data of 16 REEs were collected.The REEs levels in the inves gated foods varied significantly.The concentra ons of cerium (Ce),dysprosium (Dy),y rium (Y),lanthanum (La),and neodymium (Nd) were rela vely high,while the remaining eleven REEs were at low levels.The mean values of total rare earth element oxides (REOs) in cereals,fresh vegetables,fresh aqua c products,fresh meats and eggs varied from 0.052 mg/kg to 0.337 mg/kg.Conclusion 16 REEs in the major foods were at very low contamina on levels in the inves gated regions. | JIANG Ding Guo YANG Jie ZHANG Shuo YANG Da Jin | 2012 | Biomedical and Environmental Sciences2012，25，3： | 28 |
| 8 | PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1-Parkin-mediated mitophagy显示文摘Mitophagy 是为损坏线粒体的特定的消除的选择 autophagy 的一种重要类型。(PINK1 )导致 PTEN 的通常认为的 kinase 蛋白质 1 催化 ubiquitin (Ub ) 的 phosphorylation 在 PINK1-Parkin-mediated mitophagy 的发作起一个关键作用。(PTEN-L ) 磷酸酶和 tensin 相当或相同的事物(PTEN ) 长是 PTEN 的最新识别的 isoform,与到它的 N 终点的 173 氨基酸的增加。这里,我们报导 PTEN-L 是经由它对 phosphorylated ubiquitin 的蛋白质磷酸酶活动的 mitophagy 的一个新奇否定管理者。我们发现 PTEN-L 在外部 mitochondrial 膜(OMM ) 本地化,而 PTEN-L 的删除支持, PTEN-L 的 overexpression 禁止, mitophagy 由各种各样的损坏线粒体的代理人导致了。机械学地, PTEN-L 能够有效地阻止 Parkin mitochondrial translocation,减少 Parkin phosphorylation,维持它的关上的不活跃的符合构造,并且禁止它的 E3 ligase 活动。更重要地, PTEN-L 在 vivo 减少 phosphorylated ubiquitin (pSer65-Ub ) 的水平,并且在 vitro,磷酸酶试金经由它的蛋白质磷酸酶活动证实那 PTEN-L dephosphorylates pSer65-Ub,独立于它的类脂化合物磷酸酶功能。一起拿,我们的调查结果为 ubiquitin 作为蛋白质磷酸酶表明 PTEN-L 的新奇功能,它抵抗在 mitophagy 正式就职和 mitophagy 的最终的抑制导致前馈控制机制的阻塞的调停 PINK1 的 ubiquitin phosphorylation。因此,理解 PTEN-L 的这新奇功能在控制 mitophagy 的分子的难题提供一关键错过片,在包括象 Parkinsons 那样的 neurodegenerative 混乱的许多重要人的疾病的一个批评过程疾病。 | Liming Wang Yik-Lam Cho Yancheng Tang Jigang Wang Jung-Eun Park Yajun Wu Chunxin Wang Yan Tong Ritu Chawla Jianbin Zhang Yin Shi Shuo Deng Guang Lu Yihua Wu Hayden Weng-Siong Tan Pornteera Pawijit Grace Gui-Yin Lim Hui-Ying Chan Jingzi Zhang Lei Fang Hanry Yu Yih-Cherng Liou Mallilankaraman Karthik Boon-Huat Bay Kah-Leong Lim Siu-Kwan Sze Celestial T. Yap Han-Ming Shen | 2018 | Cell Research2018，28，8： | 25 |
| 9 | Air pollution characteristics and their relationship with emissions and meteorology in the Yangtze River Delta region during 2014–2016显示文摘With rapid economic growth and urbanization, the Yangtze River Delta(YRD) region in China has experienced serious air pollution challenges. In this study, we analyzed the air pollution characteristics and their relationship with emissions and meteorology in the YRD region during 2014–2016. In recent years, the concentrations of all air pollutants, except O3,decreased. Spatially, the PM2.5, PM10, SO2, and CO concentrations were higher in the northern YRD region, and NO2 and O3 were higher in the central YRD region. Based on the number of non-attainment days(i.e., days with air quality index greater than 100), PM2.5 was the largest contributor to air pollution in the YRD region, followed by O3, PM10, and NO2.However, particulate matter pollution has declined gradually, while O3 pollution worsened.Meteorological conditions mainly influenced day-to-day variations in pollutant concentrations. PM2.5 concentration was inversely related to wind speed, while O3 concentration was positively correlated with temperature and negatively correlated with relative humidity.The air quality improvement in recent years was mainly attributed to emission reductions.During 2014–2016, PM2.5, PM10, SO2, NOx, CO, NH3, and volatile organic compound(VOC)emissions in the YRD region were reduced by 26.3%, 29.2%, 32.4%, 8.1%, 15.9%, 4.5%, and0.3%, respectively. Regional transport also contributed to the air pollution. During regional haze periods, pollutants from North China and East China aggravated the pollution in the YRD region. Our findings suggest that emission reduction and regional joint prevention and control helped to improve the air quality in the YRD region. | Tao Ma Fengkui Duan Kebin He Yu Qin Dan Tong Guannan Geng Xuyan Liu Hui Li Shuo Yang Siqi Ye Beiyao Xu Qiang Zhang Yongliang Ma | 2019 | Journal of Environmental Sciences2019，31，9： | 26 |
| 10 | Establishment and application of an artificial intelligence diagnosis system for pancreatic cancer with a faster region-based convolutional neural network显示文摘Background:Early diagnosis and accurate staging are important to improve the cure rate and prognosis for pancreatic cancer.This study was performed to develop an automatic and accurate imaging processing technique system,allowing this system to read computed tomography(CT)images correctly and make diagnosis of pancreatic cancer faster.Methods:The establishment of the artificial intelligence(AI)system for pancreatic cancer diagnosis based on sequential contrastenhanced CT images were composed of two processes:training and verification.During training process,our study used all 4385 CT images from 238 pancreatic cancer patients in the database as the training data set.Additionally,we used VGG16,which was pretrained in ImageNet and contained 13 convolutional layers and three fully connected layers,to initialize the feature extraction network.In the verification experiment,we used sequential clinical CT images from 238 pancreatic cancer patients as our experimental data and input these data into the faster region-based convolution network(Faster R-CNN)model that had completed training.Totally,1699 images from 100 pancreatic cancer patients were included for clinical verification.Results:A total of 338 patients with pancreatic cancer were included in the study.The clinical characteristics(sex,age,tumor location,differentiation grade,and tumor-node-metastasis stage)between the two training and verification groups were insignificant.The mean average precision was 0.7664,indicating a good training ejffect of the Faster R-CNN.Sequential contrastenhanced CT images of 100 pancreatic cancer patients were used for clinical verification.The area under the receiver operating characteristic curve calculated according to the trapezoidal rule was 0.9632.It took approximately 0.2 s for the Faster R-CNN AI to automatically process one CT image,which is much faster than the time required for diagnosis by an imaging specialist.Conclusions:Faster R-CNN AI is an effective and objective method with high accuracy for the diagnosis of pancreatic cancer. | Shang-Long Liu Shuo Li Yu-Ting Guo Yun-Peng Zhou Zheng-Dong Zhang Shuai Li Yun Lu | 2019 | Chinese Medical Journal2019，，23： | 23 |
| 11 | Salvianolic acid B ameliorates depressive-like behaviors in chronic mild stress-treated mice: involvement of the neuroinflammatory pathway显示文摘瞄准:主要压抑的混乱(MDD ) 是削弱与 neurotransmitter-neuroendocrine 系统和 neuroinflammatory 回答的机能障碍联系的心理混乱。Salvianolic 酸 B (SalB ) 显示出许多药理学活动,包括反煽动性,抗氧化剂和 neuroprotective 效果。在这研究,我们检验了 SalB 是否在一个长期的温和压力(厘米) 产生了像抗抑郁剂的行动老鼠模型,并且探索了位于 SalB.Methods 的像抗抑郁剂的行动下面的机制:老鼠受到一个厘米范例 6 个星期。在最后 3 个星期内,老鼠是每天管理的 SalB (20 mg· kg −1·d−1, ip ) 或积极控制药 imipramine (20 mg· kg −1·d−1, ip ) 。像镇静剂的行为用蔗糖偏爱测试,强迫的游泳测试(FST ) ,和尾巴暂停测试(TST ) 被评估。在马头鱼尾的怪兽和外皮的 cytokines 的基因表示与 RT-PCR 被分析。血浆皮质脂酮(CORT ) 和服的 cytokines 层次是有一个 ELISA 工具包的 assayed。在大脑纸巾的神经 apoptosis 和 microglial 激活用 immunofluorescence staining.Results 被检测:SalB 或 imipramine 的管理颠倒了对待厘米的老鼠的减少的蔗糖偏爱比率,并且显著地减少了他们在 FST 和 TST 的不动时间。SalB 的管理显著地减少了支持 inflammatory cytokines IL-1β 的表示;并且 TNF-α,并且显著地增加了反煽动性的 cytokines IL-10 和 TGF-β 的表示;在对待厘米的老鼠的马头鱼尾的怪兽和外皮,并且使他们的提高的血浆 CORT 层次正常化,而 imipramine 的管理显著地没在对待厘米的老鼠的马头鱼尾的怪兽和外皮影响在支持 inflammatory 和反煽动性的 cytokines 之间的不平衡。最后, SalB 的管理显著地减少了在马头鱼尾的怪兽和外皮的导致厘米的 apoptosis 和 microglia 激活,而 imipramine 的管理没在马头鱼尾的怪兽和 cortex.Conclusion 在导致厘米的 apoptosis 和 microglia 激活上有重要效果:SalB 施加在导致厘米的老鼠的像抗抑郁剂的效果消沉建模的有势力,它与禁止被联系在马头鱼尾的怪兽和外皮的 microglia 相关的 apoptosis。 | Jin-qiang ZHANG Xiao-hui WU Yi FENG Xiao-fang XIE Yong-hua FAN Shuo YAN Qiu-ying ZHAO Cheng PENG Zi-li YOU | 2016 | Acta Pharmacologica Sinica2016，37，9： | 19 |
| 12 | Efficient Gene Targeting in Zebrafish Mediated by a Zebrafish-Codon-Optimized Cas9 and Evaluation of Off-Targeting Effect显示文摘Targeted genome modifications with the Cas9/gRNA system derived from the clustered regularly interspaced short palindromic repeat/CRISPR-associated(CRISPR/Cas)system have been successfully used in cultured human cells as well as in most model organisms,including zebrafish(Danio rerio),mouse,and fruit fly(Chang et al.,2013;Cong et al.,2013; | Da Liu Zhanxiang Wang An Xiao Yutian Zhang Wenyuan Li Yao Zu Shaohua Yao Shuo Lin Bo Zhang | 2014 | Journal of Genetics and Genomics2014，41，1： | 18 |
| 13 | Hidden policy ciphertext-policy attribute-based encryption with keyword search against keyword guessing attack显示文摘Attribute-based encryption with keyword search(ABKS) enables data owners to grant their search capabilities to other users by enforcing an access control policy over the outsourced encrypted data. However,existing ABKS schemes cannot guarantee the privacy of the access structures, which may contain some sensitive private information. Furthermore, resulting from the exposure of the access structures, ABKS schemes are susceptible to an off-line keyword guessing attack if the keyword space has a polynomial size. To solve these problems, we propose a novel primitive named hidden policy ciphertext-policy attribute-based encryption with keyword search(HP-CPABKS). With our primitive, the data user is unable to search on encrypted data and learn any information about the access structure if his/her attribute credentials cannot satisfy the access control policy specified by the data owner. We present a rigorous selective security analysis of the proposed HP-CPABKS scheme, which simultaneously keeps the indistinguishability of the keywords and the access structures. Finally,the performance evaluation verifies that our proposed scheme is efficient and practical. | Shuo QIU Jiqiang LIU Yanfeng SHI Rui ZHANG | 2017 | Science China(Information Sciences)2017，60，5： | 18 |
| 14 | Geochronology and Geochemistry of Middle–Late Ordovician Granites and Gabbros in the Erguna Region,NE China:Implications for the Tectonic Evolution of the Erguna Massif显示文摘Zircon U-Pb ages, Hf isotope data and whole-rock major and trace element data for the Middle to Late Ordovician gabbros and granites in the Erguna Massif, NE China were presented in this paper. The petrogenesis of these rocks and the Early Paleozoic tectonic evolution of the massif were discussed. Zircons from the granites and gabbros are of magmatic origin based on their cathodoluminescence(CL) images. The 206Pb/238 U ages obtained from 20 spots on zircons from the granites range from 446±9 to 464±10 Ma, yielding a weighted mean age of 455±10 Ma; and 16 spots on zircons from the gabbros range from 465±10 to 466±7 Ma, yielding a weighted mean age of 465±2 Ma. Chemically, the Late Ordovician granites in the Erguna Massif are weakly peraluminous and similar to A-type granites. The granites and gabbros are all enriched in light rare earth elements and large ion lithophile elements(e.g., Rb, K), and depleted in heavy rare earth elements and high field strength elements(e.g., Nb, Ta, and Ti); they all exhibit marked negative Eu anomalies. Their zircon εHf(t) values range mainly from +1.86 to +6.21(for the granites) and +1.39 to +3.89(for the gabbros), except for one spot with a value of-0.27(for a gabbro). The TDM1 ages for the gabbros and TDM2 ages for the granites vary from 928 to 1 091 Ma and from 1 287 to 1 675 Ma, respectively. It is concluded that the primary magma of the granites could have been derived by partial melting of Mesoproterozoic newly accreted crustal material, whereas the primary magma of the gabbros originated by partial melting of a depleted mantle wedge that had been metasomatized by fluids derived from a subducted slab. These Middle–Late Ordovician granites and gabbros constitute a typical bimodal igneous rock association, implying an extensional environment that was probably related to the post-collisional development of the Erguna and Xing'an massifs in the early Early Paleozoic. | Shuo Zhao Wenliang Xu Wei Wang Jie Tang Yihan Zhang | 2014 | Journal of Earth Science2014，25，5： | 17 |
| 15 | Electromagnetic wave absorption in reduced graphene oxide functionalized with Fe3O4/Fe nanorings显示文摘我们与嵌入的 Fe 3 由化学热水的生长的 O 4/Fe nanorings (FeNR@rGO ) 。我们作为吸收材料的新奇电磁波说明这些 nanocomposites 的使用。有不同作文的 nanocomposites 的电磁波吸收性质被调查。准备过程和 nanocomposite 作文被优化完成最好的电磁波吸收性质。有 GO:-Fe 2 为 3 h 在 H 2/Ar 退火准备的 1:1 的 O 3 团比率展出了最好的性质。这件 nanocomposite 样品(厚度 = 4.0 公里) 在 9.16 GHz 显示出最小的反射率 of-23.09 dB。当反射率是更少的 than-10 dB,光谱宽度直到 3.9 GHz 时,乐队范围是 7.4-11.3 GHz。当时,优点的这些数字典型地具有一样的数量级与传统的铁的氧化物材料显示出的价值相比。然而, FeNR@rGO 能乐意地作为因为我们建议的生产方法与大量生产标准高度兼容,吸收材料的微波被使用。 | Yi Ding Long Zhang Qingliang Liao Guangjie Zhang Shuo Liu Yue Zhang | 2016 | Nano Research2016，9，7： | 17 |
| 16 | PM_(2.5)-bound polycyclic aromatic hydrocarbons(PAHs) in Beijing:Seasonal variations,sources,and risk assessment显示文摘Polycyclic aromatic hydrocarbons(PAHs) have been of health concern due to its carcinogenesis and mutagenesis. In this study, we aimed to assess the variations, sources, and lifetime excessive cancer risk(ECR) attributable to PAHs bound to ambient particulate matters with aerodynamic diameter less than 2.5 μm(PM_(2.5)) in metropolitan Beijing, China. We collected24-hour integrated PM_(2.5) samples on daily basis between November 2014 and June 2015 across both central heating(cold months) and non-heating(warm months) seasons, and further analyzed the PAH components in these daily PM_(2.5) samples. Our results showed that total concentrations of PM_(2.5)-bound PAHs varied between(88.6 ± 75.4) ng/m^3 in the cold months and(11.0 ± 5.9) ng/m^3 in the warm months. Benzo[a]pyrene(Ba P), the carcinogenic marker of PAHs,averaged at 5.7 and 0.4 ng/m^3 in the cold and warm months, respectively. Source apportionment analyses illustrated that gasoline, biomass burning, diesel, coal combustion and cooking were the major contributors, accounting for 12.9%, 17.8%, 24.7%, 24.3% and 6.4% of PM_(2.5)-bound PAHs, respectively. The BaP equivalent lifetime ECR from inhalation of PM_(2.5)-bound PAHs was 16.2 cases per million habitants. Our results suggested that ambient particulate reduction from energy reconstruction and adaption of clean fuels would result in reductions PM_(2.5)-bound PAHs and its associated cancer risks. However, as only particulate phased PAHs was analyzed in the present study, the concentration of ambient PAHs could be underestimated. | Baihuan Feng Lijuan Li Hongbing Xu Tong Wang Rongshan Wu Jie Chen Yi Zhang Shuo Liu Steven Sai Hang Ho Junji Cao Wei Huang | 2019 | Journal of Environmental Sciences2019，31，3： | 17 |
| 17 | Cytotoxin-associated gene-A-seropositive virulent strains of Helicobacter pylori and atherosclerotic diseases: a systematic review显示文摘客观 A 系统的元分析被执行探索联系细胞毒素的基因的角色 -- Helicobacterpylori 的 A (CagA ) seropositive 紧张(H。塔门)在从 Medline , EMBASE , CBMdisc , CNKI 和 Cochrane 的动脉粥样硬化患者 diseases.Data 来源数据的致病,合作数据库是 searched.Similar 搜索策略被用于每这些 databases.Study 选择评论在 H.pylori 的易传染的、长期的剧毒的 CagA 紧张上被限制为盒子控制研究,包含 ischemic 击和冠的心疾病的风险,不合格的研究被排除。二个评论家独立地提取了数据并且完全估计了学习 quality.Results 26 盒子控制研究(ischemic 击上的 11 研究和冠的心疾病上的 15 研究) 被检索并且考虑。联合数据表明长期的 seropositive H 的剧毒的紧张。pylori 感染有增加 ischemic 中风和冠的心疾病的风险的一个趋势,产出 2.68 的分享的 Ors (95% CI:2.20, 3.27 ) 并且 2.11 (95% CI:1.70, 2.62 ) 分别地。我们也执行了亚群分析,把全部的人口划分成白种人和中国亚群。通过亚群分析,没有重要差别在我们的结果支持的 subgroups.Conclusions 之间被发现 CagA-seropositive 紧张感染显著地与危险性被联系到 ischemic 击和冠的心疾病的假设。有动脉粥样硬化患者疾病的协会的大小需要被未来的研究证实, CagA-seropositive 紧张根除上的研究是更重要的。 | ZHANG Shuo GUO Yang MA Yan TENG Yue | 2008 | Chinese Medical Journal2008，，10： | 17 |
| 18 | Investigation on the broadband electromagnetic wave absorption properties and mechanism of Co3O4- nanosheets/reduced-graphene-oxide composite显示文摘cobaltosic-oxide-nanosheets/reduced-graphene-oxide 合成(CoNSs@RGO ) 成功地作为一个小宽带电磁波吸收器被准备。样品厚度的效果和数量合成在吸收上补充说性质彻底地被调查到石蜡样品。由于公司 3 O 4, 很高,波浪吸收材料的 surface-to-volume 比率在吸收性质正在导致大改进。为 3.6 公里的厚度的 CoNSs@RGO 合成 was-45.15 dB 的最大的茶点损失,和有思考损失 below-10 dB 的最好的吸收带宽是有 2.9 公里的厚度的 7.14 GHz。另外,微波吸收的山峰与增加吸收涂层的厚度向低频率区域变了。电磁波吸收的机制被归因于阻抗象 RGO 的绝缘的松驰和极化一样匹配 CoNSs@RGO。比作以前报导的吸收材料, CoNSs@RGO 在高频率乐队为申请作为一个无足轻重的人和高度有效的吸收材料显示出更好的性能。 | Yi Ding Zheng Zhang Baohe Luo Qingliang Liao Shuo Liu Yichong Liu Yue Zhang | 2017 | Nano Research2017，10，3： | 16 |
| 19 | miR-221/222 activate the Wnt/β-catenin signaling to promote triple-negative breast cancer显示文摘 | Sanhong Liu Zifeng Wang Zukai Liu Shuo Shi Zhaoran Zhang Jiawei Zhang Haifan Lin | 2018 | Journal of Molecular Cell Biology2018，10，4： | 16 |
| 20 | MiR-27a Promotes Hepatocellular Carcinoma Cell Proliferation Through Suppression of its Target Gene Peroxisome Proliferator-activated Receptor γ显示文摘 | Shuo Li Jing Li Bing-Yuan Fei Dan Shao Yue Pan Zhan-Hao MO Bao-Zhen Sun Dan Zhang Xiao Zheng Ming Zhang Xue-Wen Zhang Li Chen | 2015 | Chinese Medical Journal2015，，7： | 15 |
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