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| 1 | 原发性低密度脂蛋白胆固醇≥4.94mmol/L的男性降低低密度脂蛋白胆固醇对心血管病的影响显示文摘原发性低密度脂蛋白胆固醇(low density lipoprotein cholesterol,LDL-C)≥4.94mmol/L(190mg/dL)的患者由于长期暴露在显著升高的LDL-C下,心血管动脉粥样硬化的风险更高。因此,对于这些患者通常建议采用他汀类药物治疗,但是缺少随机试验证据支持。在该研究中,研究者提供了一些降低LDL-C对心血管病影响的初级预防资料。 | Vallejo-Vaz AJ Robertson M Catapano AL Watts GF Kastelein JJ Packard CJ Ford I Ray KK 黄洁 叶鹏 | 2017 | 中华高血压杂志2017，25，10： | 5 |
| 2 | A framework infrageneric classification of Carex (Cyperaceae) and its organizing principles显示文摘Phylogenetic studies of Carex L.(Cyperaceae)have consistently demonstrated that most subgenera and sections are para-or polyphyletic.Yet,taxonomists continue to use subgenera and sections in Carex classification.Why?The Global Carex Group(GCG)here takes the position that the historical and continued use of subgenera and sections serves to(i)organize our understanding of lineages in Carex,(ii)create an identification mechanism to break the~2000 species of Carex into manageable groups and stimulate its study,and(iii)provide a framework to recognize morphologically diagnosable lineages within Carex.Unfortunately,the current understanding of phylogenetic relationships in Carex is not yet sufficient for a global reclassification of the genus within a Linnean infrageneric(sectional)framework.Rather than leaving Carex classification in its current state,which is misleading and confusing,we here take the intermediate steps of implementing the recently revised subgeneric classification and using a combination of informally named clades and formally named sections to reflect the current state of our knowledge.This hybrid classification framework is presented in an order corresponding to a linear arrangement of the clades on a ladderized phylogeny,largely based on the recent phylogenies published by the GCG.It organizes Carex into six subgenera,which are,in turn,subdivided into 62 formally named Linnean sections plus 49 informal groups.This framework will serve as a roadmap for research on Carex phylogeny,enabling further development of a complete reclassification by presenting relevant morphological and geographical information on clades where possible and standardizing the use of formal sectional names. | Eric H.Roalson Pedro Jiménez-Mejías Andrew L.Hipp Carmen Benítez-Benítez Leo P.Bruederle Kyong-Sook Chung Marcial Escudero Bruce A.Ford Kerry Ford Sebastian Gebauer Berit Gehrke Marlene Hahn Muhammad Qasim Hayat Mathias H.Hoffmann Xiao-Feng Jin Sangtae Kim Isabel Larridon Étienne Léveillé-Bourret Yi-Fei Lu Modesto Luceño Enrique Maguilla Jose IgnacioMárquez-Corro Santiago Martín-Bravo Tomomi Masaki Mónica Míguez Robert F.C.Naczi Anton A.Reznicek Daniel Spalink Julian R.Starr Uzma Tamara Villaverde Marcia J.Waterway Karen L.Wilson and Shu-Ren Zhang | 2021 | Journal of Systematics and Evolution2021，59，4： | 3 |
| 3 | Budd-Chiari syndrome:A single-center experience显示文摘AIM:To investigate challenges,risk factors,prognostic indicators,and treatment outcomes associated with Budd-Chiari syndrome(BCS)at a tertiary care center.METHODS:A retrospective cohort study was conducted at the University of Pennsylvania in patients with a diagnosis of BCS or hepatic vein thrombosis.All patients receiving care at the University of Pennsylvania,and who had at least 2 clinical encounters in the University of Pennsylvania Health system from January1,2008 to September 10,2013 were eligible for study inclusion.Data were extracted from the electronic medical record of each patient,and recorded in a secure Research Electronic Data Capture database.Logistic regression analyses were applied to identify predictors of outcome of liver transplant(LT)or death.RESULTS:Between January 1,2008 and September10,2013,forty-seven patients were identified.Median age was 42.4 years.Thirty-one(66.0%)were women.A majority were Caucasian(68.1%).At diagnosis,43(91.5%)patients had ascites,27(57.4%)patients had a hematologic disorder associated with a hypercoagulable state and 26(55.3%)had cirrhosis.Forty(85.1%)patients were on anticoagulation(AC),30(63.8%)of whom were maintained on warfarin.Two patients(4.3%)underwent thrombolytic therapy.A transjugular intrahepatic portosystemic shunt(TIPS)was placed in21(44.7%)patients,19(90.5%)of whom were also on AC.Twenty-one(44.7%)received AC alone.Over a median of 974 d,8(17.0%)patients received LT,and10(21.3%)died.The median time from listing to death was 26 mo[interquartile range(IQR)=16,65)].TIPS with AC was utilized more frequently in younger patients(P=0.02).Age,cirrhosis and chronic kidney disease(CKD)were significant predictors of LT or death.CONCLUSION:AC alone was employed as frequently as TIPS with AC,though the latter was used more frequently in younger patients with polycythemia vera.There were no significant differences in treatment outcome regardless of the therapeutic intervention employed.Significant predictors of poor prognosis included age,cirrhosis and CKD. | Tanya M Pavri Alan Herbst Rajender Reddy Kimberly A Forde | 2014 | World Journal of Gastroenterology2014，20，43： | 2 |
| 4 | Acute sensorineural hearing loss associated with peginterferon and ribavirin combination therapy during hepatitis C treatment: Outcome after resumption of therapy显示文摘Peginterferon and ribavirin combination therapy for the treatment of hepatitis C virus (HCV) is well known to be associated with significant adverse effects. Sensorineural hearing loss, that in most cases is unilateral, has been reported as a consequence of therapy with both non-pegylated and pegylated interferon (pegIFN) but is not a well-known adverse effect. We report a 45-year-old Caucasian woman who developed acute sensorineural hearing loss 2 mo after starting therapy with pegIFN-α 2b and ribavirin for the treatment of chronic HCV, genotype 1a. She did not report the hearing loss to the hepatitis clinic until L mo,later whereupon therapy was promptly discontinued.Although her serum alanine aminotransferase (ALT)normalized and her HCV-RNA became undetectable after 12 wk of pegIFN and ribavirin therapy, after discontinuation,her HCV-RNA became detectable with significant elevations of serum ALT. Four months after initial discontinuation,the patient re-commenced pegIFN and ribavirin combination therapy. After 44 of 48 wk of therapy, the patient's liver biochemistry has normalized and the HCV-RNA is undetectable. She has not developed worsening of her hearing loss and hearing on the left-side is unaffected.Both patients and physicians should be aware that sensorineural hearing loss may occur with pegIFN therapy.Our experience suggests that re-institution of therapy is not always associated with further hearing impairment. | Victor K Wong Cindy Cheong-Lee Jo-Ann E Ford Eric M Yoshida | 2005 | World Journal of Gastroenterology2005，11，34： | 2 |
| 5 | An arabidopsis MADs box gene that controls nutrient - induced changes in root architecture显示文摘 | Zhang H M and Forde B G | 1998 | Science1998，279，： | 2 |
| 6 | Regulation of Arabidopsis root development by nitrateavailability显示文摘 | Zhang H M Forde B G | 2000 | Journal of Experimental Botany2000，51，342： | 2 |
| 7 | Abortifacient effects of a unique class of vasoactive lipids from Pinus ponderosa needles显示文摘 | FORD S P ROSAZZA J P AL-MAHMOUD M S | 1999 | J Anita Sci1999，77，8： | 1 |
| 8 | Efficacy and safety of paliperidone extended-release tablets: results of a 6-week, randomized, placebo-controlled study 显示文摘 | Marder SR Kramer M Ford L | 2007 | Biol Psychiatry2007，62，12： | 1 |
| 9 | Use of mineral trioxide aggregate for repair of furcal perforation 显示文摘 | Pitt Ford TR Torabinejad M Mckendry DJ | 1995 | Oral Surg1995，79，： | 1 |
| 10 | Differential contribution of current and cumulative in dices of lead dose to neuropsychological performance by age 显示文摘 | BLEEXER M L LINDGREN K N FORD D P | 1997 | Neurology1997，48，： | 1 |
| 11 | Cosmic strings and black holes显示文摘 | Aryal M Ford L Vilenkin A | 1986 | Phys Rev1986，34，： | 1 |
| 12 | A marked disparity between the expression of prion protein and its message neurones of cns显示文摘 | Ford M J Burton L J Li H | 2002 | Neuroscience2002，111，： | 1 |
| 13 | Genetic improvement in the yield of winter:afurther evaluation 显示文摘 | AUSTIN R B FORD M A MORGAN C L | 1989 | J Agric Sci1989，112，： | 1 |
| 14 | Issues over high speed non invasive monitoring of railway trackbed显示文摘 | Clark M Gordon M Forde M C | 2004 | NDT and E International2004，37，2： | 1 |
| 15 | Cervical spondylosis: the role of anterior instrumentation after decompression and fusion 显示文摘 | Zaveri GR Ford M | 2001 | J Spinal Disord2001，14，1： | 1 |
| 16 | Evaluation of the oral subchronic tox-icity of HHCB(1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta-g-2-benzopyran)in the rat显示文摘 | Api A M Ford R A | 1999 | Toxi-cology Letters1999，111，12： | 1 |
| 17 | Delivery of RNAi mediators显示文摘 | Ford L P Toloue M M | 2010 | Wiley Interdiscip Rev RNA2010，1，： | 1 |
| 18 | Retrieval- induced forgetting: A developmental study 显示文摘 | FORD R M KEATING S PATEL R | 2004 | British Journal of Development Psychology2004，22，： | 1 |
| 19 | Separation and analysis of the diastereomers and enantiomers of cypermethrin and related compounds显示文摘 | Edwards D P Ford M G | 1997 | Journal of Chromatography A1997，777，2： | 1 |
| 20 | Perceptions of hypertension and contributing personal and environmental factors a- mong rural Southern African American women 显示文摘 | Ford CD Kim M J Dancy BL | 2009 | Ethn D2009，19，4： | 1 |
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