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| 1 | Gastroesophageal reflux disease and morbid obesity: To sleeve or not to sleeve?显示文摘Laparoscopic sleeve gastrectomy(LSG) has reached wide popularity during the last 15 years, due to the limited morbidity and mortality rates, and the very good weight loss results and effects on comorbid conditions. However, there are concerns regarding the effects of LSG on gastroesophageal reflux disease(GERD). The interpretation of the current evidence is challenged by the fact that the LSG technique is not standardized, and most studies investigate the presence of GERD by assessing symptoms and the use of acid reducing medications only. A few studies objectively investigated gastroesophageal function and the reflux profile by esophageal manometry and 24-h p H monitoring, reporting postoperative normalization of esophageal acid exposure in up to 85% of patients with preoperative GERD, and occurrence of de novo GERD in about 5% of cases. There is increasing evidence showing the key role of the surgical technique on the incidence of postoperative GERD. Main technical issues are a relative narrowing of the mid portion of the gastric sleeve, a redundant upper part of the sleeve(both depending on the angle under which the sleeve is stapled), and the presence of a hiatal hernia. Concomitant hiatal hernia repair is recommended. To date, either medical therapy with proton pump inhibitors or conversion of LSG to laparoscopic Rouxen-Y gastric bypass are the available options for the management of GERD after LSG. Recently, new minimally invasive approaches have been proposed in patients with GERD and hypotensive LES: the LINX? Reflux Management System procedure and the Stretta? procedure. Large studies are needed to assess the safety and long-term efficacy of these new approaches. In conclusion, the recent publication of p H monitoring data and the new insights in the association between sleeve morphology and GERD control have led to a wider acceptance of LSG as bariatric procedure also in obese patients with GERD, as recently stated in the 5^(th) International Consensus Conference on sleeve gastrectomy. | Fabrizio Rebecchi Marco E Allaix Marco G Patti Francisco Schlottmann Mario Morino | 2017 | World Journal of Gastroenterology2017，23，13： | 4 |
| 2 | Which is the best catheter to perform atrial fibrillation ablation? A comparison between standard ThermoCool, SmartTouch, and Surround Flow catheters显示文摘 | Luigi Sciarra Paolo Golia Andrea Natalizia Ermenegildo Ruvo Serena Dottori Antonio Scarà Alessio Borrelli Lucia Luca Marco Rebecchi Alessandro Fagagnini Alberto Bandini Fabrizio Guarracini Marcello Galvani Leonardo Calò | 2014 | Journal of Interventional Cardiac Electrophysiology2014，，： | 1 |
| 3 | Randomized Controlled Trial of Laparoscopic Heller Myotomy Plus Dor Fundoplication Versus Nissen Fundoplication for Achalasia: Long-Term Results显示文摘 | Fabrizio Rebecchi Claudio Giaccone Eleonora Farinella Roberto Campaci Mario Morino | 2008 | Annals of Surgery2008，，6： | 1 |
| 4 | The short esophagus: Intraoperative assessment of esophageal length显示文摘 | Sandro Mattioli Maria Luisa Lugaresi Mario Costantini Alberto Del Genio Natale Di Martino Landino Fei Uberto Fumagalli Vincenzo Maffettone Luigi Monaco Mario Morino Fabrizio Rebecchi Riccardo Rosati Mauro Rossi Stefano Santi Vincenzo Trapani Giovanni Zani | 2008 | The Journal of Thoracic and Cardiovascular Surgery2008，，： | 1 |
| 5 | Randomized Controlled Trial of Laparoscopic Heller Myotomy Plus Dor Fundoplication Versus Nissen Fundoplication for Achalasia: Long-Term Results显示文摘 | Fabrizio Rebecchi Claudio Giaccone Eleonora Farinella Roberto Campaci Mario Morino | 2008 | Annals of Surgery2008，，6： | 1 |
| 6 | Bariatric Surgery Improves Urinary Incontinence but Not Anorectal Function in Obese Women显示文摘 | Gitana Scozzari Fabrizio Rebecchi Claudio Giaccone Paolo Chiaro Massimiliano Mistrangelo Mario Morino | 2013 | Obesity Surgery2013，，7： | 1 |
| 7 | Comparison of partners-heart failure algorithm vs care alert in remote heart failure management显示文摘AIM: To compare the utility of the partners-heart failure(HF) algorithm with the care alert strategy for remote monitoring,in guiding clinical actions oriented to treat impending HF.METHODS: Consecutive cardiac resynchronizationdefibrillator recipients were followed with biweekly automatic transmissions. After every transmission,patients received a phone contact in order to check their health status,eventually followed by clinical actions,classified as 'no-action','non-active' and 'active'. Active clinical actions were oriented to treat impending HF. The sensitivity,specificity,positive and negative predictive values and diagnostic accuracy of the partners-HF algorithm vs care alert in determining active clinical actions oriented to treat pre-HF status and to prevent an acute decompensation,were also calculated.RESULTS: The study population included 70 patients with moderate to advanced systolic HF and QRS duration longer than 120 ms. During a mean follow-up of 8 ± 2 mo,665 transmissions were collected. No deaths or HF hospitalizations occurred. The sensitivity and specificity of the partners-HF algorithm for active clinical actions oriented to treat impending HF were 96.9%(95%CI: 0.96-0.98) and 92.5%(95%CI: 0.90-0.94) respectively. The positive and negative predictive values were 84.6%(95%CI: 0.82-0.87) and 98.6%(95%CI: 0.98-0.99) respectively. The partners-HF algorithm had an accuracy of 93.8%(95%CI: 0.92-0.96) in determining active clinical actions. With regard to active clinical actions,care alert had a sensitivity and specificity of 11.05%(95%CI: 0.09-0.13) and 93.6% respectively(95%CI: 0.92-0.95). The positive predictive value was 42.3%(95%CI: 0.38-0.46); the negative predictive value was 71.1%(95%CI: 0.68-0.74). Care alert had an accuracy of 68.9%(95%CI: 0.65-0.72) in determining active clinical actions.CONCLUSION: The partners-HF algorithm proved higher accuracy and sensitivity than care alert in determining active clinical actions oriented to treat impending HF. Future studies in larger populations should evaluate partners-HF ability to improve HF-related clinical outcomes. | Leonardo Calo’ Annamaria Martino Claudia Tota Alessandro Fagagnini Renzo Iulianella Marco Rebecchi Luigi Sciarra Giuseppe Giunta Maria Grazia Romano Roberto Colaceci Antonio Ciccaglioni Fabrizio Ammirati Ermenegildo de Ruvo | 2015 | World Journal of Cardiology2015，7，12： | 0 |
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