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154篇 您的检索式:作者名="Engelman A"
    题名 作者 年代 出处 被引量
1MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling显示文摘ENGELMAN J A ZEJNULLAHU K MITSUDOMI T 2007Science2007,316,5827:1
2Caveolin-3 null mice show a loss of caveolae,changes in the microdomain distribution of the dystrophin- glycoprotein complex,and t-tubule abnormalities显示文摘Galbiati F Engelman J A Volonte D 2001The Journal of Biological Chemistry2001,276,21:1
3Tar- geted down-regulation of caveolin-3 is sufficient to inhibit myotube formation in differentiating C2C12 myoblasts-transient activation of p38 mitogen- activated protein kinase is required for induction of caveolin-3 expression and subsequent myotube for- mation显示文摘Galbiati F Volonte D Engelman J A 1999Journal of Biological Chemistry1999,274,30:1
4Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers 显示文摘Engelman J A Chert L Tan X 2008Nat Med2008,14,12:1
5Activity and safety of crizotinib in patients with ALK -positive non-small-cell lung cancer: updated results from a phase 1 study显示文摘D Ross Camidge Yung-Jue Bang Eunice L Kwak A John Iafrate Marileila Varella-Garcia Stephen B Fox Gregory J Riely Benjamin Solomon Sai-Hong I Ou Dong-Wan Kim Ravi Salgia Panagiotis Fidias Jeffrey A Engelman Leena Gandhi Pasi A J?nne Daniel B Costa Geoffrey 2012Lancet Oncology2012,,10:1
6Mechanisms of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer显示文摘Engelman J A Janne P A 0,,10:1
7Critical contacts between HIV-I integrase and viral DNA identified by structure-based analysis and photo-crosslinking显示文摘Jenkins TM Esposito D Engelman A 1997EMBO J1997,16,22:1
8MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling显示文摘ENGELMAN J A ZEJNULLAHU K MITSUDOMI T 2007Science2007,316,5827:1
9MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling显示文摘ENGELMAN J A ZEJNULLAHU K MITSUDOMI T 2007Science2007,316,5827:1
10Targeting PI3K signalling in cancer:opportunities,challenges and limitations显示文摘ENGELMAN J A 2009Nat Rev Cancer2009,9,8:1
11Ginkgo biloba extract (Egb) improves postischemic function in isolated preconditioned working rat hearts显示文摘Tosaki A Engelman DT Pali T 1994Coron Artery Dis1994,5,5:1
12The evolution of diabetic response to ischemia/reperfusion and preconditioning in isolated working rat hearts显示文摘Tosaki A Engelman DT Engelman RM 1996Cardiovasc Res1996,31,:1
13Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR - amplified lung cancer 显示文摘Jeffrey A Engelman Toru Mukohara Kreshnik Zejnullahu 2006J Clin Invest2006,116,:1
14The evolution of diabetic response to ischemia/ reperfusion and preconditioning in isolated working rat heart显示文摘TOSAKI A ENGELMEN D T ENGELMAN R M 1996Cardiovasc Res1996,31,:1
15Fast-track recovery of the coronary bypass patient 显示文摘Engelman R M Rousou J A Flack J E 3rd 1994Ann Thorac Surg1994,58,6:1
16Tricuspid annuloplasty,Fiveand one-half years experience with 78 patients显示文摘Boyd A D Engelman R M Isom O W 1974Thorac Cardiovasc Surg1974,68,:1
17Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis显示文摘Alice T Shaw Beow Y Yeap Benjamin J Solomon Gregory J Riely Justin Gainor Jeffrey A Engelman Geoffrey I Shapiro Daniel B Costa Sai-Hong I Ou Mohit Butaney Ravi Salgia Robert G Maki Marileila Varella-Garcia Robert C Doebele Yung-Jue Bang Kimary Kulig Pauli 2011Lancet Oncology2011,,11:1
18Activity and safety of crizotinib in patients with ALK -positive non-small-cell lung cancer: updated results from a phase 1 study显示文摘D Ross Camidge Yung-Jue Bang Eunice L Kwak A John Iafrate Marileila Varella-Garcia Stephen B Fox Gregory J Riely Benjamin Solomon Sai-Hong I Ou Dong-Wan Kim Ravi Salgia Panagiotis Fidias Jeffrey A Engelman Leena Gandhi Pasi A J?nne Daniel B Costa Geoffrey 2012Lancet Oncology2012,,10:1
19PF00299804, an irreversible pan-ERBB inhibitor, is effective in lung cancer models with EGFR and ERBB2 mutations that are resistant to gefitinib 显示文摘Engelman J A Zejnullahu K Gale C M 2007Cancer Res2007,67,11:1
20The evolution of diabetic response to ischemia/reperfusion and preconditioning in isolated working rat hearts显示文摘Tosaki A Engelman DT Engelman RM 1996Cardiovasc Res1996,31,4:1
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