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| 1 | A high-energy-density sodium-ion full battery based on tin anode显示文摘Sodium-ion batteries(SIBs) have been considered as promising candidates for large-scale energy storage, owing to the high abundance and low cost of sodium(Na) resources. However, the development of full SIB has been hindered by low energy density because of the sluggish kinetics of large Na^+. Here, we report a full SIB with commercial tin(Sn) anode, cross-linked Na_3V_2(PO_4)_3/carbon nanotubes composites(NVP-CNT) cathode, and ether-based electrolyte. Sn is capable of delivering high reversible capacity via formation of Na15 Sn4 and stable solid-electrolyte interface(SEI) in initial cycles. Meanwhile, the NASICON-type NVP enables ultrafast and stable Na^+intercalation/extraction, and the incorporation of CNT can improve its electrical conductivity. The assembled full SIB delivers high output voltage of ~3.2 V, high energy density of 253.4 W h kg^(-1) at1600 W kg^(-1) based on total mass of both cathode and anode, and remarkable capacity retention of 96.1% after 180 cycles. These merit construction of high-energy full SIBs and will promote the development of SIBs. | Mingming Song Chenchen Wang Dongfeng Du Fujun Li Jun Chen | 2019 | Science China Chemistry2019，62，5： | 3 |
| 2 | Facile synthesis of porous Pd nanoflowers with excellent catalytic activity towards CO oxidation显示文摘Microorganism-mediated,hexadecyltrimethylammonium chloride(CTAC)-directed(MCD) method was employed in this work to synthesize Pd nanoflowers(PdNFs).Proper Pichia pastoris cells(PPCs) dosage,ascorbic acid(AA),Pd(NO_3)_2 and CTAC concentrations were essential for the growth of the PdNFs.The size of the assynthesized PdNFs could be tuned by adjusting the amount of Pd(NO_3)_2 solution and dosage of PPCs used.Characterization techniques such as X-ray diffraction,transmission electron microscopy,and X-ray photoelectron spectroscopy were used to verify the nature of the PdNFs.Finally the PdNF/PPC nanocomposites were immobilized onto TiO_2 supports to obtain bio-PdNF/TiO_2 catalysts which showed excellent catalytic activity for CO oxidation,obtaining 100%conversion at 100℃ and remaining stable over a period of 52 h of reaction time. | Tareque Odoom-Wubah Mingming Du Williams Brown Osei Daohua Sun Jiale Huang Qingbiao Li | 2015 | Chinese Journal of Chemical Engineering2015，23，11： | 2 |
| 3 | Mieroorganism-mediated,CTAB-directed synthesis of hierarchically branched Au-nanowire/Eseheriehia eoli nanoeomposites with strong near-infrared absorbanee显示文摘 | Haixian Yang Mingming Du Tareque Odoom-Wubah | 2014 | Journal of Chemical Technology and Bioteehnology2014，，89： | 1 |
| 4 | Treatment of oily sludgeby advanced oxidation process显示文摘 | Guolin Jing Mingming Luan Wenting Du | 2012 | Environ Earth Sci2012，，67： | 1 |
| 5 | Analysis and Improvement on a Mobile Payment Protocol with Outsourced Verification in Cloud Service显示文摘Mobile wallet is a very convenient means of mobile payment to allow the clients to conduct the payment via their mobile devices. To reduce the computation burden of resources-constraint mobile devices, a few mobile wallet protocols with outsourced verification in cloud computing were proposed. But in some of the protocols, there exist the risk of a colluding attack of the customer and the untrusted cloud server. In this paper, we propose an improved protocol, in which the payment information is protected by Hash function and random number. The malicious customer and cloud server cannot change the payment information to conduct a collusion forgery attack to defraud the merchant. The security analysis indicates that the proposed improved protocol can enhance the security in terms of correctness, unforgeability and traceability without increasing the computational burden. | KANG Baoyuan DU Jianqi SI Lin XIE Mingming | 2019 | Wuhan University Journal of Natural Sciences2019，24，3： | 1 |
| 6 | Assembly of highly efficient aqueous light-harvesting system from sequence-defined peptoids for cytosolic microRNA detection显示文摘Precisely controlled spatial distributions of artificial light-harvesting systems in aqueous media are of significant importance for mimicking natural light-harvesting systems;however,they are often restrained by the solubility and the aggregation-caused quenching effect of the hydrophobic chromophores.Herein,we report one highly efficient artificial light-harvesting system based on peptoid nanotubes that mimic the hierarchical cylindrical structure of natural systems.The high crystallinity of these nanotubes enabled the organization of arrays of donor chromophores with precisely controlled spatial distributions,favoring an efficient Förster resonance energy transfer(FRET)process in aqueous media.This FRET system exhibits an extremely high efficiency of 98.6%with a fluorescence quantum yield of 40%and an antenna effect of 29.9.We further demonstrated the use of this artificial light-harvesting system for quantifying miR-210 within cancer cells.The fluorescence intensity ratio of donor to acceptor is linearly related to the concentration of intercellular miR-210 in the range of 3.3–156 copies/cell.Such high sensitivity in intracellular detection of miR-210 using this artificial light-harvesting system offers a great opportunity and pathways for biological imaging and detection,and for the further creation of microRNA(miRNA)toolbox for quantitative epigenetics and personalized medicine. | Yang Song Xiaoli Cai Mingming Wang Dan Du Yuehe Lin Chun-Long Chen | 2024 | Nano Research2024，17，2： | 1 |
| 7 | IonicliquidenhancedimmobilizationofbiosynthesizedAunanoparticlesonTS1towardefficientcatalystsforpropyleneepoxidation显示文摘 | Du Mingming ZhanGuowu YangXin etal | 2011 | JCatal2011，283，2： | 1 |
| 8 | Acetylation of ezrin regulates membrane–cytoskeleton interaction underlying CCL18-elicited cell migration显示文摘Ezrin,a membrane–cytoskeleton linker protein,plays an essential role in cell polarity establishment,cell migration,and division.Recent studies show that ezrin phosphorylation regulates breast cancer metastasis by promoting cancer cell survivor and promotes intrahepatic metastasis via cell migration.However,it was less characterized whether there are additional post-translational modifications and/or post-translational crosstalks on ezrin underlying context-dependent breast cancer cell migration and invasion.Here we show that ezrin is acetylated by p300/CBP-associated factor(PCAF)in breast cancer cells in response to CCL18 stimulation.Ezrin physically interacts with PCAF and is a cognate substrate of PCAF.The acetylation site of ezrin was mapped by mass spectrometric analyses,and dynamic acetylation of ezrin is essential for CCL18-induced breast cancer cell migration and invasion.Mechanistically,the acetylation reduced the lipid-binding activity of ezrin to ensure a robust and dynamic cycling between the plasma membrane and cytosol in response to CCL18 stimulation.Biochemical analyses show that ezrin acetylation prevents the phosphorylation of Thr567.Using atomic force microscopic measurements,our study revealed that acetylation of ezrin induced its unfolding into a dominant structure,which prevents ezrin phosphorylation at Thr567.Thus,these results present a previously undefined mechanism by which CCL18-elicited crosstalks between the acetylation and phosphorylation on ezrin control breast cancer cell migration and invasion.This suggests that targeting PCAF signaling could be a potential therapeutic strategy for combating hyperactive ezrin-driven cancer progression. | Xiaoyu Song Wanjuan Wang Haowei Wang Xiao Yuan Fengrui Yang Lingli Zhao McKay Mullen Shihao Du Najdat Zohbi Saravanakumar Muthusamy Yalei Cao Jiying Jiang Peng Xia Ping He Mingrui Ding Nerimah Emmett Mingming Ma Quan Wu Hadiyah-Nicole Green Xia Ding Dongmei Wang Fengsong Wang Xing Liu | 2020 | Journal of Molecular Cell Biology2020，12，6： | 1 |
| 9 | Green syn- thesis of Au/TS-1 catalysts via two novel modes and their surprising performance for propylene epoxidation 显示文摘 | Zhan Guowu Du Mingming Huang Jiale | 2011 | Catalysis Communication2011，12，： | 1 |
| 10 | Microorganism-mediated,CTAB-directed synthesis of hierarchically branched Au-nanowire/Escherichia coli nanocomposites with strong near-infrared absorbance显示文摘 | Yang Haixian Du Mingming Tareque Odoom-Wubah | 2014 | Journal of Chemical Technology and Biotechnology2014，89，9： | 1 |
| 11 | Liquid Phase Oxidation of Benzyl Alcohol to Benzaldehyde with Novel Uncalcined Bioreduction Au Catalysts:High Activity and Durability 显示文摘 | Zhan Guowu Huang Jiale Du Mingming | 2012 | Chem Eng J2012，187，1： | 1 |
| 12 | Microorganism-Mediated,CTAB-Directed Synthesis of Hierarchically Branched Au-Nanowire/Escherichia Coli Nanocomposites with Strong Near-Infrared Absorbance显示文摘 | Yang Haixian Du Mingming Odoom-Wubah Tareque | 2014 | J Chem Technol Biotechnol2014，89，9： | 1 |
| 13 | Sequence-Defined Nanotubes Assembled from IR780-Conjugated Peptoids for Chemophototherapy of Malignant Glioma显示文摘Near-infrared(NIR)laser-induced phototherapy through NIR agents has demonstrated the great potential for cancer therapy.However,insufficient tumor killing due to the nonuniform heat or cytotoxic singlet oxygen(1 O2)distribution over tumors from phototherapy results in tumor recurrence and inferior outcomes.To achieve high tumor killing efficacy,one of the solutions is to employ the combinational treatment of phototherapy with other modalities,especially with chemotherapeutic agents.In this paper,a simple and effective multimodal therapeutic system was designed via combining chemotherapy,photothermal therapy(PTT),and photodynamic therapy(PDT)to achieve the polytherapy of malignant glioma which is one of the most aggressive tumors in the brain.IR-780(IR780)dye-labeled tube-forming peptoids(PepIR)were synthesized and self-assembled into crystalline nanotubes(PepIR nanotubes).These PepIR nanotubes showed an excellent efficacy for PDT/PTT because the IR780 photosensitizers were effectively packed and separated from each other within crystalline nanotubes by tuning IR780 density;thus,a self-quenching of these IR780 molecules was significantly reduced.Moreover,the efficient DOX loading achieved due to the nanotube large surface area contributed to an efficient and synergistic chemotherapy against glioma cells.Given the unique properties of peptoids and peptoid nanotubes,we believe that the developed multimodal DOX-loaded PepIR nanotubes in this work offer great promises for future glioma therapy in clinic. | Xiaoli Cai Mingming Wang Peng Mu Tengyue Jian Dong Liu Shichao Ding Yanan Luo Dan Du Yang Song Chun-Long Chen Yuehe Lin | 2021 | Research2021，，1： | 1 |
| 14 | TMEM16A inhibits angiotensin Ⅱ-induced basilar artery smooth muscle cell migration in a WNK1-dependent manner显示文摘Vascular smooth muscle cell(VSMC) migration plays a critical role in the pathogenesis of many cardiovascular diseases.We recently showed that TMEM16 A is involved in hypertensioninduced cerebrovascular remodeling.However,it is unclear whether this effect is related to the regulation of VSMC migration.Here,we investigated whether and how TMEM16 A contributes to migration in basilar artery smooth muscle cells(BASMCs).We observed that AngⅡ increased the migration of cultured BASMCs,which was markedly inhibited by overexpression of TMEM16 A.TMEM16 A overexpression inhibited AngⅡ-induced RhoA/ROCK2 activation,and myosin light chain phosphatase(MLCP)and myosin light chain(MLC20) phosphorylation.But AnsⅡ-induced myosin light chain kinase(MLCK)activation was not affected by TMEM16 A.Furthermore,a suppressed activation of integrinβ3/FAK pathway,determined by reduced integrinβ3 expression,FAK phosphorylation and F-actin rearrangement,was observed in TMEM16 A-overexpressing BASMCs upon AngⅡ stimulation.Contrary to the results of TMEM16 A overexpression,silencing of TMEM16 A showed the opposite effects.These in vitro results were further demonstrated in vivo in basilar arteries from VSMC-specific TMEM10 A transgenic mice during AngⅡ-induced hypertension.Moreover,we observed that the inhibitory effect of TMEM16 A on BASMC migration was mediated by decreasing the activation of WNK1,a Cl^(-)-sensitive serine/threonine kinase.In conclusion,this study demonstrated that TMEM16 A suppressed AnsⅡ-induced BASMC migration,thus contributing to the protection against cerebrovascular remodeling during AngⅡ-infused hypertension.TMEM16 A may exert this effect by suppressing the RhoA/ROCK2/MLCP/MLC20 and integrinβ3/FAK signaling pathways via inhibiting WNK1.Our results suggest that TMEM16 A may serve as a novel therapeutic target for VSMC migration-related diseases,such as vascular remodeling. | Huaqing Zheng Xiaolong Li Xin Zeng Chengcui Huang Mingming Ma Xiaofei Lv Yajuan Zhang Lu Sun Guanlei Wang Yanhua Du Yongyuan Guan | 2021 | Acta Pharmaceutica Sinica B2021，11，12： | 1 |
| 15 | Effect of Tire Repeated Root Modal on Tire Modelling with Experimental Modal显示文摘The effect of tire repeated root modal(RRM)on tire modeling with an experimental modal is studied.Firstly,a radial tire with radial and tangential RRMs is tested and analyzed.By multi-point exciting of the radial tire,a multiple reference frequency domain method based on a least squares(LMS PolyMAX)algorithm is used to identify modal parameters.Then,modal stability diagram(MSD),modal indication function(MIF)and modal assurance criteria(Auto-MAC)matrix are utilized to induce multiple inputs multiple outputs(MIMO)frequency response function(FRF)matrixes.The tests reveal that notable repeated roots exist in both radial and tangential response modes.Their modal frequencies and damping factors are approximately the same,the amplitudes of modal vectors are in the same order of magnitude,and the mode shapes are orthogonal.Based on the works mentioned,the method of trigonometric series modal shapes fitting is adopted,the effects of RRM model on tire modeling with a vertical experimental modal are discussed.The final results show that the effects of considering the RRM shapes are equivalent to the tire mode shapes depended on rotating the tire's different exciting points during tire modeling,and since considering the RRM,the tire mode shapes can be unified and fixed during tire modeling. | Zhenfeng Wang Yongchang Du Mingming Dong Liang Gu | 2017 | Journal of Beijing Institute of Technology2017，26，1： | 0 |
| 16 | Genome-wide linkage mapping of QTL for root hair length in a Chinese common wheat population显示文摘Root hairs are fast growing,ephemeral tubular extensions of the root epidermis that aid nutrient and water uptake.The aim of the present study was to identify QTL for root hair length(RHL)using 227 F8 recombinant inbred lines(RILs)derived from a cross of Zhou 8425 B(Z8425 B)and Chinese Spring(CS),and to develop convenient molecular markers for markerassisted breeding in wheat.Analysis of variance of root hair length showed significant differences(P<0.01)among RILs.The genetic map for QTL analysis consisted of 3389 unique SNP markers.Using composite interval mapping,four major QTL(LOD>2.5)for RHL were identified on chromosomes 1 B(2),2 D and 6 D and four putative QTL(2≤LOD≤2.5)were detected on chromosomes 1 A,3 A,6 B,and 7 B,explaining 3.32%–6.52%of the phenotypic variance.The positive alleles for increased RHL of QTL on chromosomes 2 D,6 B and 6 D(QRhl.cau-2 D,q Rhl.cau-6 B,and QRhl.cau-6 D)were contributed by Z8425 B,and CS contributed positive QTL alleles on chromosomes 1 A(q Rhl.cau-1 A),1 B(QRhl.cau-1 B.1 and QRhl.cau-1 B.2),3 A(q Rhl.cau-3 A)and 7 B(q Rhl.cau-7 B).STARP markers were developed for QRhl.cau-1 B.1,QRhl.cau-2 D,QRhl.cau-6 D,and q Rhl.cau-7 B.Haplotype and association analysis indicated that the positive allele of QRhl.cau-6 D had been strongly selected in Chinese wheat breeding programs.Collectively,the identified QTL for root hair length are likely to be useful for marker-assisted selection. | Feng Huang Zhaoyan Chen Dejie Du Panfeng Guan Lingling Chai Weilong Guo Zhaorong Hu Mingming Xin Huiru Peng Yingyin Yao Zhongfu Ni | 2020 | The Crop Journal2020，8，6： | 0 |
| 17 | Mass spectrometry analysis of intact protein N-glycosylation signatures of cells and sera in pancreatic adenocarcinomas显示文摘Pancreatic cancer is among the most malignant cancers,and thus early intervention is the key to better survival outcomes.However,no methods have been derived that can reliably identify early precursors of development into malignancy.Therefore,it is urgent to discover early molecular changes during pancreatic tumorigenesis.As aberrant glycosylation is closely associated with cancer progression,numerous efforts have been made to mine glycosylation changes as biomarkers for diagnosis;however,detailed glycoproteomic information,especially site-specific N-glycosylation changes in pancreatic cancer with and without drug treatment,needs to be further explored.Herein,we used comprehensive solid-phase chemoenzymatic glycoproteomics to analyze glycans,glycosites,and intact glycopeptides in pancreatic cancer cells and patient sera.The profiling of N-glycans in cancer cells revealed an increase in the secreted glycoproteins from the primary tumor of MIA PaCa-2 cells,whereas human sera,which contain many secreted glycoproteins,had significant changes of glycans at their specific glycosites.These results indicated the potential role for tumor-specific glycosylation as disease biomarkers.We also found that AMG-510,a small molecule inhibitor against Kirsten rat sarcoma viral oncogene homolog(KRAS)G12C mutation,profoundly reduced the glycosylation level in MIA PaCa-2 cells,suggesting that KRAS plays a role in the cellular glycosylation process,and thus glycosylation inhibition contributes to the anti-tumor effect of AMG-510. | Mingming XU Zhaoliang LIU Wenhua HU Ying HAN Zhen WU Sufeng CHEN Peng XIA Jing DU Xumin ZHANG Piliang HAO Jun XIA Shuang YANG | 2024 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2024，25，1： | 0 |
| 18 | Author correction to‘TMEM16A inhibits angiotensin II-induced basilar artery smooth muscle cell migration in a WNK1-dependent manner'[Acta Pharmaceutica Sinica B 11(2021)3994-4007]显示文摘The authors regret that picture errors were found in the Fig.II,Fig.4L and Fig.6C owing to copy and paste mistakes during the process of using AI tools to check published images.Due to the large number of original images,these errors were not detected by manual inspection when preparing the corrected representative images previously. | Huaqing Zheng Xiaolong Li Xin Zeng Chengcui Huang Mingming Ma Xiaofei Lv Yajuan Zhang Lu Sun Guanlei Wang Yanhua Du Yongyuan Guan | 2023 | Acta Pharmaceutica Sinica B2023，13，9： | 0 |
| 19 | A highly conserved amino acid in high molecular weight glutenin subunit 1Dy12 contributes to gluten functionality and processing quality in wheat显示文摘Bread wheat(Triticum aestivum L.)is one of the most commonly consumed staples worldwide,with widespread uses in foods such as breads,noodles,cakes,and cookies(Veraverbeke and Delcour,2002).The specific cooking properties of wheat products are mainly conferred by the gluten proteins contained in wheat grains(Delcour et al.,2012).High molecular weight glutenin subunits(HMW-GSs)are important constituents of wheat gluten proteins,largely determining gluten elasticity and processing quality(Branlard and Dardevet,1985;Payne et al.,1988). | Changfeng Yang Qian Chen Mingming Xin Zhenqi Su Jinkun Du Weilong Guo Zhaorong Hu Jie Liu Huiru Peng Zhongfu Ni Qixin Sun Yingyin Yao | 2023 | Journal of Genetics and Genomics2023，50，11： | 0 |
| 20 | Characterization of a new hexaploid triticale 6D(6A) substitution line with increased grain weight and decreased spikelet number显示文摘Hexaploid triticale(×Triticosecale,AABBRR)is an important forage crop and a promising energy plant.Transferring D-genome chromosomes or segments from common wheat(Triticum aestivum)into hexaploid triticale is attractive in improving its economically important traits.Here,a hexaploid triticale 6D(6A)substitution line Lin 456 derived from the cross between the octoploid triticale line H400 and the hexaploid wheat Lin 56 was identified and analyzed by genomic in situ hybridization(GISH),fluorescence in situ hybridization(FISH),and molecular markers.The GISH analysis showed that Lin 456 is a hexaploid triticalewith 14 rye(Secale cereale)chromosomes and 28 wheat chromosomes,whereas non-denaturing fluorescence in situ hybridization(ND-FISH)and molecular marker analysis revealed that it is a 6D(6A)substitution line.In contrast to previous studies,the signal of Oligo-pSc119.2 was observed at the distal end of 6DL in Lin 456.The wheat chromosome 6D was associatedwith increased grain weight and decreased spikelet number using the genotypic data combined with the phenotypes of the F2 population in the three environments.The thousand-grain weight and grain width in the substitution individuals were significantly higher than those in the non-substitution individuals in the F2 population across the three environments.We propose that the hexaploid triticale 6D(6A)substitution line Lin 456 can be a valuable and promising donor stock for genetic improvement during triticale breeding. | Zhiyu Feng Zhongqi Qi Dejie Du Mingyi Zhang Aiju Zhao Zhaorong Hu Mingming Xin Yingyin Yao Huiru Peng Qixin Sun Zhongfu Ni | 2019 | The Crop Journal2019，7，5： | 0 |
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