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| 1 | Comparative evaluation of microscopy,OptiMAL® and 18S rRNA gene based multiplex PCR for detection of Plasmodium falciparum & Plasmodium vivax from field isolates of Bikaner,India显示文摘Objective:To evaluate microscopy,OptiMAL? and multiplex PCR for the identification of Plasmodium falciparum(P.falciparum) and Plasmodium vivax(P.vivax) from the field isolates of Bikaner,Rajasthan(Northwest India).Methods:In this study,a multiplex PCR(P.falciparum and P.vivax) was further developed with the incorporation of Plasmodium malariae(P.malariae) specific primer and also a positive control.The performance of microscopy,plasmodium lactate dehydrogenase(pLDH) based malaria rapid diagnostic test OptiMAL? and 18S rRNA gene based multiplex PCR for the diagnosis of P.falciparum and P.vivax was compared.Results:The three species multiplex PCR if.falciparum,P.vivax and P.malariae) with an inbuilt positive control was developed and evaluated.In comparison with multiplex PCR,which showed the sensitivity and specificity of 99.36%(95%CI,98.11%-100.00%) and 100.00%(95%CI,100.00%-100.00%),the sensitivity and specificity of microscopy was 90.44%(95%CI,88.849-95.04%) and 99.22%(95% CI,97.71%-100.00%),and OptiMAL? was 93.58%(95%CI,89.75%-97.42%) and 97.69%(95%CI, 95.10%-100.00%).The efficiencies were 99.65%,95.10%and 95.45%for multiplex PCK.microscopy and OptiMAL?.respectively.Conclusions:Our results raise concerns over the overall sensitivities of microscopy and OptiMAL?,when compared to the multiplex PCR and thus stress the need for new molecular interventions in the accurate detection of the malarial parasites.This further highlights the fact that further developments are needed to improve the performance of rapid diagnostic tests at field level. | Deepak Pakalapati Shilpi Garg Sheetal Middha Abhishek Kochar Amit Kumar Subudhi Boopathi Pon Arunachalam Sanjay Kumar Kochar Vishal Saxena Pareek RP Jyoti Acharya Dhanpat Kumar Kochar Ashis Das | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，5： | 3 |
| 2 | Narrow-band imaging without high magnification to differentiate polyps during real-time colonoscopy: improvement with experience显示文摘 | Jason N. Rogart Dhanpat Jain Uzma D. Siddiqui Tal Oren Joseph Lim Priya Jamidar Harry Aslanian | 2008 | Gastrointestinal Endoscopy2008，，6： | 2 |
| 3 | Role of interstitial cells of Cajal in motility disorders of the bowel显示文摘 | Dhanpat Jain Khalid Moussa Manish Tandon Joan Culpepper-Morgan Deborah D Proctor | 2003 | The American Journal of Gastroenterology2003，，3： | 1 |
| 4 | Kinetics of Chromium Cr(Ⅲ)Oxidation to Chromium (Ⅵ) by Reaction With Manganese Dioxide显示文摘 | L Edmond Eary and Dhanpat RaL | 1987 | Environ Sci TechonL1987，21，： | 1 |
| 5 | Histological-hemodynamic correlation in cirrhosis—a histological classification of the severity of cirrhosis显示文摘 | Satish Nagula Dhanpat Jain Roberto J. Groszmann Guadalupe Garcia-Tsao | 2005 | Journal of Hepatology2005，，1： | 1 |
| 6 | Role of interstitial cells of Cajal in motility disorders of the bowel显示文摘 | Dhanpat Jain Khalid Moussa Manish Tandon Joan Culpepper-Morgan Deborah D Proctor | 2003 | The American Journal of Gastroenterology2003，，3： | 1 |
| 7 | cadherin, expression intract Gas- trointestinal endometriosis ,possible role in deep tissue invasion and development of malignancy显示文摘 | Katy V P Vinita P Dhanpat J | 2010 | Modern Pathology2010，23，3： | 1 |
| 8 | Benign tumors and tumor-like le- sions of the gallbladder and extrahepatic biliary tract显示文摘 | Katharine VP Dhanpat J | 2010 | Di- agnostic Histopathology2010，16，： | 1 |
| 9 | Host factors are dominant in the development of post-liver transplant non-alcoholic steatohepatitis显示文摘Non-alcoholic fatty liver disease(NAFLD) is a recognized problem in patients after orthotopic liver transplantation and may lead to recurrent graft injury. As the increased demand for liver allografts fail to match the available supply of donor organs, split liver transplantation(SLT) has emerged as an important technique to increase the supply of liver grafts. SLT allows two transplants to occur from one donor organ, and provides a unique model for observing the pathogenesis of NAFLD with respect to the role of recipient environmental and genetic factors. Here we report on two recipients of a SLT from the same deceased donor where only one developed non-alcoholic steatohepatitis(NASH), suggesting that host factors are critical for the development of NASH. | Salih Boga Armando Salim Munoz-Abraham Manuel I Rodriguez-Davalos Sukru H Emre Dhanpat Jain Michael L Schilsky | 2016 | World Journal of Hepatology2016，8，15： | 0 |
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