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| 1 | Resection of pancreatic cystic neoplasms in recurrent acute pancreatitis prevents recurrent pancreatitis but does not identify more malignancies显示文摘BACKGROUND Recurrent acute pancreatitis(RAP)may be a presenting feature of and an indication for resection of pancreatic cysts,including intra-ductal papillary mucinous neoplasm(IPMN).Few data are available regarding the prevalence of malignancy and post-operative RAP in this population.AIM To study the role of resection to help prevent RAP and analyze if presentation as RAP would be a predictor for malignancy.METHODS This retrospective study assessed 172 patients who underwent surgical resection of pancreatic cystic neoplasms at a university hospital between 2002 and 2016.The prevalence of preoperative high-risk cyst features,and of neoplasia was compared between patients with and without RAP.To identify the cause of pancreatitis,all the patients had a detailed history of alcohol,smoking,medications obtained,and had cross-sectional imaging(contrast-enhanced computed tomography/magnetic resonance imaging)and endoscopic ultrasound to look for gallstone etiology and other structural causes for pancreatitis.The incidence of RAP post-resection was the primary outcome.RESULTS IPMN accounted for 101 cases(58.7%){[branch duct(BD)59(34.3%),main duct(MD)42](24.4%)}.Twenty-nine(16.9%)presented with RAP(mean 2.2 episodes):15 had BD-IPMN,8 MD-IPMN,5 mucinous cystic neoplasm and 1 serous cystic neoplasm.Malignancy was similar among those with vs without RAP for all patients[6/29(20.7%)vs 24/143(16.8%)]and IPMN patients[6/23(26.1%)vs 23/78(29.5%)],although tended to be higher with RAP in BD-IPMN,[5/15(33.3%)vs 3/44(6.8%),P=0.04].At mean follow-up of 7.2 years,1(3.4%)RAP patient had post-resection RAP.The mean episodes of acute pancreatitis before vs after surgery were 3.4 vs 0.02(P<0.0001).CONCLUSION Malignancy was not increased in patients with pancreatic cystic neoplasms who have RAP compared to those without RAP.In addition,specific cyst characteristics were not clearly associated with RAP.The incidence of RAP was markedly decreased in almost all patients following cyst resection. | Thiruvengadam Muniraj Harry R Aslanian Loren Laine Priya A Jamidar James F Farrell Kisha A Mitchell Ronald R Salem | 2021 | World Journal of Gastroenterology2021，27，15： | 3 |
| 2 | Narrow-band imaging without high magnification to differentiate polyps during real-time colonoscopy: improvement with experience显示文摘 | Jason N. Rogart Dhanpat Jain Uzma D. Siddiqui Tal Oren Joseph Lim Priya Jamidar Harry Aslanian | 2008 | Gastrointestinal Endoscopy2008，，6： | 2 |
| 3 | Brazilian and African passive margins of the Central Segment of the South Atlantic Ocean: Kinematic constraints显示文摘 | Daniel Aslanian Maryline Moulin Jean-Louis Olivet Patrick Unternehr Luis Matias Fran?ois Bache Marina Rabineau Hervé Nouzé Frauke Klingelheofer Isabelle Contrucci Cinthia Labails | 2008 | Tectonophysics2008，，1： | 1 |
| 4 | Brazilian and African passive margins of the Central Segment of the South Atlantic Ocean:Kinematic constraints显示文摘 | Aslanian D Moulin M Olivet J | | 0，，： | 1 |
| 5 | EUS-guided FNA of solid pancreatic masses: a prospective, randomized trial comparing 22-gauge and 25-gauge needles显示文摘 | Uzma D. Siddiqui Federico Rossi Lawrence S. Rosenthal Manmeet S. Padda Visvanathan Murali-Dharan Harry R. Aslanian | 2009 | Gastrointestinal Endoscopy2009，，6： | 1 |
| 6 | Targeted disruption of the scavenger receptor and chemokine CXCL16 accderates atherosclerosis 显示文摘 | Aslanian AM Charo IF | 2006 | Circulation2006，114，6： | 1 |
| 7 | Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics 显示文摘 | Aslanian A Iaquinta PJ Verona R | 2004 | Genes Dev2004，18，12： | 1 |
| 8 | Targeted disruption of the scavenger receptor and ehemokine CXCL16 aeeelerates atheroselerosis 显示文摘 | Aslanian AM Charo IF | 2006 | Circulation2006，114，6： | 1 |
| 9 | Inhibition of Btk with CC-292provides early pharmacodynamic assessment of activity in mice and humans显示文摘 | Evans EK Tester R Aslanian S | 2013 | J Pharmacol Exp Ther2013，346，： | 1 |
| 10 | p53-deficient cells rely on ATM-and ATR-mediated checkpoint signaling through the p38 MAPK/MK2pathway for survival after DNA damage显示文摘 | Reinhardt HC Aslanian AS Lees JA | 2007 | Cancer Cell2007，11，2： | 1 |
| 11 | A new starting point for the South and Equatorial Atlantic Ocean显示文摘 | Moulin M Aslanian D Unternehr P | 2010 | Earth-Sci- ence Reviews2010，98，12： | 1 |
| 12 | Immunohistochemical findings in active vitiligo including depigmenting lesions and non-lesional skin显示文摘 | Aslanian FMNP Noe RAM Antelo DP | 2008 | Open Derm J2008，2，： | 1 |
| 13 | Asparagine syn- thetase expression alone is sufficient to induce L-asparagi- nase resistance in MOLT-4 human leukaemia cells 显示文摘 | Aslanian AM Fletcher BS Kilberg MS | 2001 | Biochem J2001，357，1： | 1 |
| 14 | AHR Conversation How Size Matters: The Question of Scale in History显示文摘 | Sebouh David Aslanian Joyce E. Chaplin Ann McGrath Kristin Mann | 2013 | The American Historical Review2013，，： | 1 |
| 15 | A new starting point for the South and Equatorial Atlantic Ocean 显示文摘 | Moulin M Aslanian D Unternehr P | 2010 | Earth Sci- ence Reviews2010，98，1： | 1 |
| 16 | Brazilian and African passive margins of the central segment of the South Atlantic Ocean: Kinematic constraints显示文摘 | Daniel Aslanian Maryline Moulin Jean-Louis Olivet et M | 2009 | Tectonophysics2009，468，： | 1 |
| 17 | M1477: A Prospective, Multicenter, Randomized, Double Blinded Controlled Study to Determine Whether a Single Dose of Intraduodenal Indomethacin Can Decrease the Incidence and Severity of Post-ERCP Pancreatitis显示文摘 | Farshad Elmi Federico Rossi Joseph K. Lim Harry R. Aslanian Uzma D. Siddiqui Fred S. Gorelick Hillary Drumm Priya A. Jamidar | 2010 | Gastrointestinal Endoscopy2010，，5： | 1 |
| 18 | Mass spectrometry for proteomics显示文摘 | Han X Aslanian A Yates JR 3rd | | 0，，05： | 1 |
| 19 | Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics 显示文摘 | Aaron Aslanian Phillip J Iaquinta | 2004 | Genes Dev2004，18，12： | 1 |
| 20 | Targeted disruption of the scavenger receptor and chemokine CXCL16 accelerates atherosclerusis显示文摘 | Aslanian AM Charo IF | 2006 | Circulation2006，114，6： | 1 |
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