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| 1 | Introduction of a multicenter online database for non-metastatic breast cancer in China显示文摘Dear Editor,Breast cancer is now the most frequently diagnosed cancer and is the fifth leading cause of cancer-related death in Chinese women. Therefore, the burden of breast cancer in China is gradually increasing. According to figures released by the Chinese Cancer Center in 2018, the number of newly diagnostic breast cancer is about 278,900 cases, accounting for 16.51%of all women who were diagnosed with the first primary malignant tumors;and 66,000 cases of breast cancer died in 2014 (Chen et al., 2016). | Yaping Yang Jieqiong Liu Min Peng Fengxi Su Xiaoming Xie Zhenzhen Liu Jundong Wu Wei Wei Dongxian Zhou Weiwen Li Ailing Zhang Guosen Su Weixiong Yang Jishang Chen Dekui Ma Yongguang Cai Kai Chen Liling Zhu Qiang Liu Erwei Song | 2020 | Science China(Life Sciences)2020，63，9： | 4 |
| 2 | DDR1 promotes LoVo cell proliferation by regulating energy metabolism显示文摘Cellular energy metabolism dysregulation is associated with colorectal cancer(CRC)development and progression.Discoidin domain receptor 1a(DDR1a),one of the five DDR1 isoforms,is closely related to cell proliferation,invasion,and apoptosis in various tumors.Whether it participates in cellular metabolic reprogramming and regulates CRC initiation and progression remains unclear.In this study,we compared the expression of DDR1 in CRC tissues and adjacent tissues from 126 postoperative CRC samples.Moreover,lentivirus-mediated DDR1a overexpression and knockdown were performed in LoVo cells,and cell viability and proliferation were determined by CCK-8 and BrdU assays,respectively.Oxygen consumption rate,extracellular acidification rate,and lactate production were used to determine the effect of DDR1a on metabolic reprogramming.Clinically,CRC patients with high DDR1 expression had poor differentiation and were at an advanced TNM stage.DDR1a promoted LoVo cell proliferation,mitochondrial function,and extracellular acidification.Moreover,DDR1a knockdown inhibited intracellular lactic acid production in LoVo cells,while a pyruvate kinase inhibitor(diamide,200μM)significantly reversed this progression.Taken together,our results reveal that DDR1 plays a crucial role in maintaining intracellular environment homeostasis through metabolic reprogramming. | Bin Xiong Zehui Xie Feixue Song Huiling Chen Xiaojuan Wang Zhengxu Jin Tiyun Han Yi Li Dekui Zhang | 2022 | Acta Biochimica et Biophysica Sinica2022，54，5： | 1 |
| 3 | Electronic tattoos based on large-area Mo2C grown by chemical vapor deposition for electrophysiology显示文摘Tattoo electronics has attracted intensive interest in recent years due to its comfortable wearing and imperceivable sensing,and has been broadly applied in wearable healthcare and human-machine interface.However,the tattoo electrodes are mostly composed of metal films and conductive polymers.Two-dimensional(2D)materials,which are superior in conductivity and stability,are barely studied for electronic tattoos.Herein,we reported a novel electronic tattoo based on large-area Mo_(2)C film grown by chemical vapor deposition(CVD),and applied it to accurately and imperceivably acquire on-body electrophysiological signals and interface with robotics.High-quality Mo_(2)C film was obtained via optimizing the distribution of gas flow during CVD growth.According to the finite element simulation(FES),bottom surface of Cu foil covers more stable gas flow than the top surface,thus leading to more uniform Mo_(2)C film.The resulting Mo_(2)C film was transferred onto tattoo paper,showing a total thickness of~3μm,sheet resistance of 60-150Ω/sq,and skin-electrode impedance of~5×10^(5)Ω.Such thin Mo_(2)C electronic tattoo(MCET in short)can form conformal contact with skin and accurately record electrophysiological signals,including electromyography(EMG),electrocardiogram(ECG),and electrooculogram(EOG).These body signals collected by MCET can not only reflect the health status but also be transformed to control the robotics for human-machine interface. | Shiyu Wang Xin Wang Weifeng Zhang Xiaohu Shi Dekui Song Yan Zhang Yan Zhao Zihan Zhao Nan Liu | 2023 | Nano Research2023，16，3： | 1 |
| 4 | Electrically conductive and highly compressible anisotropic MXene-wood sponges for multifunctional and integrated wearable devices显示文摘Although piezoresistive sensors have wide applications in human motion detection and wearable elec-tronics,it is still a challenge to produce multifunctional and integrated sensors with wide working ranges and linear sensing responses.Herein,electrically conductive,highly compressible,and structurally anisotropic MXene-wood(MW)sponges are fabricated by converting balsa wood blocks to compressible wood sponges with extremely low density and highly anisotropic porous structure,followed by deco-rating with conductive MXene sheets.The MW sponge is utilized to assemble a piezoresistive sensor with a large working range of 0-25 kPa,wide linear sensing ranges of 5%-50%and 0-180°,and excellent long-term reliability under a bending angle of 30°for 5000 cycles.Additionally,the sensor is suitable for monitoring practical human physiological signals including pulse beating,and finger and wrist bending.An all-MW sponge-based multifunctional and integrated sensing system is constructed by integrating the MW sponge piezoresistive sensor,the MW sponge-based solid-state supercapacitor,and the MW sponge electrophysiological electrodes.The sensing system can concurrently detect surface electromyogram and tactile pressures,and hence realize real-time closed-loop controls.The multifunctional and integrated MW sponge sensing system would have great potentials in real-time pressure recognition and human-machine interfaces. | Dekui Song Mei-Jiao Zeng Peng Min Xue-Qin Jia Fu-Lin Gao Zhong-Zhen Yu Xiaofeng Li | 2023 | Journal of Materials Science & Technology2023，，13： | 1 |
| 5 | Erratum to: Electronic tattoos based on large-area Mo2C grown by chemical vapor deposition for electrophysiology显示文摘Erratum to Nano Research 2023,16(3):4100−4106 http://gffzzd3cc09b8251d45dfsuu6kvpckqcqx6b6k.ffgz.tsg.suse.edu.cn/10.1007/s12274-023-5423-y In the first pages of the maintext and the ESM of the original version of this paper,the order of affiliations of the authors was in a wrong sequence.“Beijing Key Laboratory of Energy Conversion and Storage Materials,College of Chemistry,Beijing Normal University,Beijing 100875,China”should be the first affiliation and“Beijing Graphene Institute,Beijing 100094,China”should be the second affiliation. | Shiyu Wang Xin Wang Weifeng Zhang Xiaohu Shi Dekui Song Yan Zhang Yan Zhao Zihan Zhao Nan Liu | 2024 | Nano Research2024，17，4： | 0 |
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