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| 1 | Current and future applications of magnetic resonance imaging and spectroscopy of the brain in hepatic encepha-lopathy显示文摘肝的脑病(他) 普通 neuro 精神病学的畸形,它从肝细胞失败或 portosystemic 与肝疾病和结果复杂化病人的功课正在推延。表明他是广泛地可变的并且从温和无临床症状的骚乱包含一个系列到深昏迷。研究兴趣集中于传播导出勇气的毒素的角色,特别地氨,胀大的大脑的开发和在导致全球 CNS 消沉和混乱功能的服的 neurotransmitter 系统的变化。直到最近,服的功能的直接调查有在人是困难的。然而,当磁性的回声光谱学( 1H 太太)检测的质子在大脑生物化学变化时,新磁性的回声成像( MRI )技术在大脑体积( coregistered MRI )和损害大脑功能( fMRI )提供对变化的评价的一个非侵略的工具,包括服的 osmolytes 的直接测量,例如 myoinositol ,充斥管理对细胞的动态平衡内在的过程的使挫折和夫酸安,包括细胞内部的水的累积。这些细胞内部的 osmolytes 的集中与 hyperammonaemia 改变。有 neuropsychiatric 缺陷并且自从先生系列的严厉的检测太太的代谢物畸形相互关联向正常术后疗法回来,技术可能具有在客观耐心的监视并且在估计各种各样的治疗政体的有效性的使用。 | VP Bob Graver M Alex Dresner Daniel M Forton Serena Counsell David J Larkman Nayna Patel Howard C Thomas Simon D Taylor-Robinson | 2006 | World Journal of Gastroenterology2006，12，19： | 8 |
| 2 | ACC/AHA guidelines for the management of patients with unstable angina and non–st-segment elevation myocardial infarction显示文摘 | Eugene Braunwald Elliott M Antman John W Beasley Robert M Califf Melvin D Cheitlin Judith S Hochman Robert H Jones Dean Kereiakes Joel Kupersmith Thomas N Levin Carl J Pepine John W Schaeffer Earl E Smith David E Steward Pierre Theroux Raymond J Gibbons J | 2000 | Journal of the American College of Cardiology2000，，3： | 4 |
| 3 | Sentinel-lymph-node resection compared with conventional axillary-lymph-node dissection in clinically node-negative patients with breast cancer: overall survival findings from the NSABP B-32 randomised phase 3 trial显示文摘 | David N Krag Stewart J Anderson Thomas B Julian Ann M Brown Seth P Harlow Joseph P Costantino Takamaru Ashikaga Donald L Weaver Eleftherios P Mamounas Lynne M Jalovec Thomas G Frazier R Dirk Noyes André Robidoux Hugh MC Scarth Norman Wolmark | 2010 | Lancet Oncology2010，，10： | 3 |
| 4 | Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial显示文摘 | Brian I Rini Bernard Escudier Piotr Tomczak Andrey Kaprin Cezary Szczylik Thomas E Hutson M Dror Michaelson Vera A Gorbunova Martin E Gore Igor G Rusakov Sylvie Negrier Yen-Chuan Ou Daniel Castellano Ho Yeong Lim Hirotsugu Uemura Jamal Tarazi David Cella | 2011 | The Lancet . 2011 (9807)2011，，9807： | 2 |
| 5 | Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial显示文摘 | Brian I Rini Bernard Escudier Piotr Tomczak Andrey Kaprin Cezary Szczylik Thomas E Hutson M Dror Michaelson Vera A Gorbunova Martin E Gore Igor G Rusakov Sylvie Negrier Yen-Chuan Ou Daniel Castellano Ho Yeong Lim Hirotsugu Uemura Jamal Tarazi David Cella | 2011 | The Lancet2011，，9807： | 2 |
| 6 | Technical outcomes of sentinel-lymph-node resection and conventional axillary-lymph-node dissection in patients with clinically node-negative breast cancer: results from the NSABP B-32 randomised phase III trial显示文摘 | David N Krag Stewart J Anderson Thomas B Julian Ann M Brown Seth P Harlow Takamaru Ashikaga Donald L Weaver Barbara J Miller Lynne M Jalovec Thomas G Frazier R Dirk Noyes André Robidoux Hugh MC Scarth Denise M Mammolito David R McCready Eleftherios P Mamo | 2007 | Lancet Oncology2007，，10： | 2 |
| 7 | Regulation of epidermal apoptosis and DNA repair by E2F1 in response to ultraviolet B radiation显示文摘 | THOMAS R B DAVID L M GUO R F | 2005 | Oncogene2005，24，15： | 1 |
| 8 | Genetic discontinuity reveal by chloroplast mierosatellite in eastern north American abies(Pinaceae) 显示文摘 | Catherine M C I Thomas R W David M M | 2000 | American Journal of Botany2000，87，： | 1 |
| 9 | The interaction between classification and rejectperformance for distance-based reject-option classifiers显示文摘 | Thomas C Landgrebe David M Tax Pavel Paclik | 2006 | Pattern Recognition Letters2006，27，8： | 1 |
| 10 | Advanced glycation end-products induce vascular dysfunction via resistance to nitric oxide and suppression of endothelial nitric oxide synthase显示文摘 | Aino Soro-Paavonen Wei-Zeng Zhang Kylie Venardos Melinda T Coughlan Emma Harris David CK Tong Daniella Brasacchio Karri Paavonen Jaye Chin-Dusting Mark E Cooper David Kaye Merlin C Thomas Josephine M Forbes | 2010 | Journal of Hypertension2010，，4： | 1 |
| 11 | Synthesis and Structural Characterization of the Normal Spinel Li O4显示文摘 | Thomas M G S R David W I F Goodenough J B | 1985 | Mater Res Bull1985，20，： | 1 |
| 12 | Comparison of elec- tronics reliability assessment approaches显示文摘 | Michael J C David E M Thomas J S | 1993 | IEEE Transactions on Reliability1993，42，4： | 1 |
| 13 | The interaction between classification and reject per- formance for distance-based reject-option classifiers 显示文摘 | Landgrebe Thomas C W Tax David M J Paclik P | 2006 | Pattern Recognition Letters2006，27，8： | 1 |
| 14 | Friction skew-stir welding of lap joints in 5083-0aluminium显示文摘 | CANTING MD DAVID S A THOMAS W M | 2005 | Science and Technology of Welding andJoining2005，10，3： | 1 |
| 15 | Galactinol synthase activity and soluble sugars in developing seeds of fourgenotypes显示文摘 | David M S David M P Thomas E C | 1987 | Plant Physiology1987，83，： | 1 |
| 16 | Rectification of data in a dynamic process using artifical neural networks 显示文摘 | DAVID M HIMMELBLAU THOMAS W K | 1996 | Computers & Chemical Engineering1996，20，6： | 1 |
| 17 | Survey research in operations management:historical analyses显示文摘 | Choi Thomas Y Hollingworth David G | 2003 | Journal of Operations Management2003，21，： | 1 |
| 18 | High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer 显示文摘 | Michael Krypuy Genni M Newnham David M Thomas | 2006 | BMC Cancer2006，6，： | 1 |
| 19 | Conversion From Cyclosporine to Tacrolimus in Patients at Risk for Chronic Renal Allograft Failure: 60-Month Results of the CRAF Study显示文摘 | Fuad S. Shihab Thomas H. Waid David J. Conti Harold Yang Michael J. Holman Laura C. Mulloy Alice K. Henning John Holman M Roy First | 2008 | Transplantation2008，，9： | 1 |
| 20 | What is the Validity Evidence for Assessments of Clinical Teaching显示文摘 | THOMAS J B DAVID A C JAYAWANT N M | 2005 | J GEN INTERN MED2005，20，： | 1 |
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