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| 1 | Unanswered questions in unsaturated soil mechanics显示文摘The last two to three decades have seen significant advances in the mechanics of unsaturated soils.It is now widely recognized that the fundamental principles in soil mechanics must cover both saturated and unsaturated soils.Nevertheless,there is still a great deal of uncertainties in the geotechnical community about how soil mechanics principles well-established for saturated soils can be extended to unsaturated soils.There is even wide skepticism about the necessity of such extension in engineering practice.This paper discusses some common pitfalls related to the fundamental principles that govern the volume change,shear strength and hydromechanical behaviour of unsaturated soils.It also attempts to address the issue of engineering relevance of unsaturated soil mechanics. | SHENG DaiChao ZHANG Sheng YU ZhiWu | 2013 | Science China(Technological Sciences)2013，56，5： | 4 |
| 2 | A symmetrisation method for non-associated unified hardening model显示文摘 | Ting Luo Zhenhua Qin Xing Feng Fei Xia Yangping Yao Daichao Sheng | 2013 | Computers and Geotechnics2013，，： | 2 |
| 3 | Transportation characteristics of motor vehicle pollutants near Beijing typical expressway显示文摘As a major source of air pollution in urban areas, the motor vehicle exhaust has attracted more and more attention due to its growing amount and serious harm to human health. It is of benefit to the pollutant control to make clear the transportation characteristics of vehicle exhausts. In this paper, the transportation characteristics of vehicle exhaust pollutants are investigated by means of the on-site measurement based on a typical Beijing expressway-Badaling expressway(G6 state expressway). The concentrations of CO, NO_x, SO_2 and particles near the expressway were obtained, by which the variations of the particle number and mass concentrations, as well as the gas pollutant volume concentrations in the vicinity of the roadways with the distance from the expressway were fitted. The results show that the gas pollutant concentrations and particle concentrations decrease almost exponentially with the distance from the expressway, which is helpful for the air pollutant database establishment and future pollution control in big cities. | LI YanLong ZHANG DaiChao JIN XinMing YANG LiJun DU XiaoZe YANG YongPing | 2016 | Science China(Technological Sciences)2016，59，3： | 2 |
| 4 | Biomarkers of aging显示文摘Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological status.Although a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly characterized.An immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this need.Here,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory factors.To fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant. | Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang Zhuo Zhang Min Zhou Rui Zhou Qingchen Zhu Zhengmao Zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen Guobing Chen Hou-Zao Chen Jun Chen Weimin Ci Bi-Sen Ding Qiurong Ding Feng Gao Jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai Zhang Hongbo Zhang Liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang Zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai Zhu Weiguo Zou Gang Pei Guang-Hui Liu | 2023 | Science China(Life Sciences)2023，66，5： | 2 |
| 5 | Finite element analysis of pile installation using large-slip frictional contact 显示文摘 | Daichao Sheng Dieter Eigenbrod K Peter Wriggers | 2005 | Computers and Geotechnics2005，32，： | 1 |
| 6 | Interpretation of Cone Factor in Undrained Soils via Full-Penetration Finite-Element Analysis显示文摘 | Daichao Sheng Lijie Cui Yousef Ansari | 2013 | International Journal of Geomechanics2013，，6： | 1 |
| 7 | TiO 2 nanotubes as drug nanoreservoirs for the regulation of mobility and differentiation of mesenchymal stem cells显示文摘 | Yan Hu Kaiyong Cai Zhong Luo Dawei Xu Daichao Xie Yuran Huang Weihu Yang Peng Liu | 2011 | Acta Biomaterialia2011，，1： | 1 |
| 8 | Frost heave due to ice lens formation in freezing soils显示文摘 | Sheng Daichao Axelsson K Knutsson S | 1995 | Hydrology Research1995，26，2： | 1 |
| 9 | DNA-binding properties of FOXP3 transcription factor显示文摘 | Jun Li Longying Jiang Xujun Liang Lingzhi Qu Daichao Wu Xiaojuan Chen Ming Guo Zhuchu Chen Lin Chen Yongheng Chen | 2017 | Acta Biochimica et Biophysica Sinica2017，49，9： | 1 |
| 10 | Pore-water pressures in freezing and thawing fine-grained soils显示文摘 | Dieter E K Sven K Daichao S | 1996 | Journal of Cold Regions Engineering1996，10，2： | 1 |
| 11 | Pore-water pressures in freezing and thawing fine-grained soils显示文摘 | Eigenbrod K D Knutsson S Sheng Daichao | | 0，，02： | 1 |
| 12 | A Potential New Frost Heave Mechanism in High-Speed Rail- way Embankments显示文摘 | SHENG Daichao ZHANG Sheng NIU Fujun | 2014 | Geotechnique2014，64，2： | 1 |
| 13 | Effect of microlimestone on properties of self-consolidating concrete with manufactured sand and mineral admixture显示文摘Self-consolidating concrete(SCC)with manufactured sand(MSCC)is crucial to guarantee the quality of concrete construction technology and the associated property.The properties of MSCC with different microlimestone powder(MLS)replacements of retreated manufactured sand(TMsand)are investigated in this study.The result indicates that high-performance SCC,made using TMsand(TMSCC),achieved high workability,good mechanical properties,and durability by optimizing MLS content and adding fy ash and silica fume.In particular,the TMSCC with 12%MLS content exhibits the best workability,and the TMSCC with 4%MLS content has the highest strength in the late age,which is even better than that of SCC made with the river sand(R sand).Though MLS content slightly affects the hydration reaction of cement and mainly plays a role in the nucleation process in concrete structures compared to silica fume and fly ash,increasing MLS content can evidently have a significant impact on the early age hydration progress.TMsand with MLS content ranging from 8%to 12%may be a suitable alternative for the Rsand used in the SCC as fine aggregate.The obtained results can be used to promote the application of SCC made with manufactured sand and mineral admixtures for concrete-based infrastructure. | Fulin Qu Wengui Li Xiaohui Zeng Zhiyu Luo Kejin Wang Daichao Sheng | 2020 | Frontiers of Structural and Civil Engineering2020，14，6： | 1 |
| 14 | A new model- ing approach for unsaturated soils using independent stress variables显示文摘 | Sheng Daichao Fredlund D G Gens A | 2008 | Can Geotech J2008，45，： | 1 |
| 15 | Collapse be- haviour of unsaturated compacted soil with different ini- tial densities显示文摘 | Sun De'an Sheng Daichao Xu Yongfu | 2007 | Can Geotech J2007，44，： | 1 |
| 16 | Frost susceptibility of soils——A confusing concept that can misguide geotechnical design in cold regions显示文摘Frost susceptibility is a concept widely used in cold region geotechnical design, to quantify the capacity of a soil in generating frost heave and frost damage. The laboratory test used to verify frost susceptibility of a soil is based on the measurement of frost heave generated in the soil under specific conditions. In reality this concept is, however, more related to the soil's potential to thaw weakening than to frost heave. Recent experimental studies show that frost non-susceptible soils like clean sand and clean gavel can also generate much ice segregation and frost heave if the conditions are favourable, hence challenging the usefulness and suitability of soil classification based on frost susceptibility. It is further shown that the concept is not suitable for design scenarios where frost heave itself is a serious hazard, such as in high-speed rail embankments. | DaiChao Sheng | 2021 | Research in Cold and Arid Regions2021，13，2： | 1 |
| 17 | A permeability function for unsaturated soils with different initial densities 显示文摘 | Cai Guoqing Zhou Annan Sheng Daichao | 2014 | Canadian Geotechnical Journal2014，51，12： | 1 |
| 18 | Nuclear RIPK1 promotes chromatin remodeling to mediate inflammatory response显示文摘RIPK1 is a master regulator of multiple cell death pathways,including apoptosis and necroptosis,and inflammation.Importantly,activation of RIPK1 has also been shown to promote the transcriptional induction of proinflammatory cytokines in cells undergoing necroptosis,in animal models of amyotrophic lateral sclerosis(ALS)and Alzheimer's disease(AD),and in human ALS and AD.Rare human genetic carriers of non-cleavable RIPK1 variants(D324V and D324H)exhibit distinct symptoms of recurrent fevers and increased transcription of proinflammatory cytokines.Multiple RIPK1 inhibitors have been advanced into human clinical trials as new therapeutics for human inflammatory and neurodegenerative diseases,such as ALS and AD.However,it is unclear whether and how RIPK1 kinase activity directly mediates inflammation independent of cell death as the nuclear function of RIPK1 has not yet been explored.Here we show that nuclear RIPK1 is physically associated with the BAF complex.Upon RIPK1 activation,the RIPK1/BAF complex is recruited by specific transcription factors to active enhancers and promoters marked by H3K4me1 and H3K27ac.Activated nuclear RIPK1 mediates the phosphorylation of SMARCC2,a key component of the BAF complex,to promote chromatin remodeling and the transcription of specific proinflammatory genes.Increased nuclear RIPK1 activation and RIPK1/BAF-mediated chromati n-remodeling activity were found in cells expressi ng non-cleavable RIPK1,and in creased enrichment of activated RIPK1 on active enhancers and promoters was found in an animal model and human pathological samples of ALS.Our results suggest that RIPK1 kinase serves as a transcriptional coregulator in nucleus that can transmit extracellular stimuli to the BAF complex to modulate chromatin accessibility and directly regulate the transcription of specific genes involved in mediating inflammatory resp onses. | Wanjin Li Bing Shan Chengyu Zou Huibing Wang Meng-Meng Zhang Hong Zhu Masanori Gomi Naito Daichao Xu Vica Jean Manuel Lauren Mifflin Zhaodong Hou John Ravits Junying Yuan | 2022 | Cell Research2022，32，7： | 1 |
| 19 | On constitutive modelling of unsaturated soils显示文摘 | Antonio Gens Marcelo Sánchez Daichao Sheng | 2006 | Acta Geotechnica2006，，3： | 1 |
| 20 | Shear banding analysis of geomaterials by strain gradient enhanced damage model显示文摘 | Jidong Zhao Daichao Sheng Weiyuan Zhou | 2005 | International Journal of Solids and Structures2005，，20： | 1 |
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