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| 1 | High-resolution geochemistry records of climate changes since late-glacial from Dajiuhu peat in Shennongjia Mountains,Central China显示文摘A peat core with depths of 297 cm was obtained from the Dajiuhu Basin(31°29′27″N,109°59′45″E,1760 m)in Hubei Province,Central China.10 AMS ages provide a time control and reveal that this core spans the past about 16.0 kaBP(calibrated age)(1 4C age:13.3 kaBP).Multi-proxy indexes analysis of geochemistry shows the following character of climate and environmental changes since about 16 kaBP:(1) The climate during the late-glacial period was cold and wet as a whole,but fluctuated continually.11.4- 12.6 cal.kaBP,12.6-15.2 cal.kaBP and 15.2-16 kaBP were corresponding respectively to the Younger Drays,Bφlling-Allerφd Warm Period and the Oldest Drays.(2)Inheriting the some climate characteristics of the late-glacial,the climate during the early-Holocene was wet and temperature increased gradually,during which an obvious dry event around 10.6 cal.kaB appeared.(3)The climate during the mid-Holocene was genarally warm and wet.During 9.2-7.5 kaBP,temperature increased gradually, precipitation was less comparatively and the 8.2 kaBP cold event which might be representative in the globe was reflected markedly.Then,multi-proxy records were relatively stable during 6.7-4.2 kaBP, which shows the best water and thermal condition in the Holocene Optimum.(4)Around 4.2 kaBP,the climate and environment transform from warm and wet to cool and dry,which may result in the collapse of the Neolithic Culture and midwifery the civilization of Xia Dynasty in this region.After 0.9 kaBP,the climate turned cool and wet.Climate and environmental changes archived in Dajiuhu peat respond to the global changes since the late-glacial period and can be contrasted to the changes recorded in other high-resolution archives from the East Asia Monsoon region,which take on the variety model that the monsoon strengthened abruptly after the late-glacial,was strong during the early Holocene,subse- quently declined and became weak after the middle Holocene with dry climate.According to our analysis,the driving mechanism should be the response of solar radiation changes in the East Asia Monsoon region at middle latitudes. | MA ChunMei ZHU Cheng ZHENG ChaoGui WU ChunLin GUAN Yong ZHAO ZhiPing HUANG LinYan HUANG Run | 2008 | Chinese Science Bulletin2008，53，S1： | 19 |
| 2 | Multifunctional barium titanate ceramics via chemical modification tuning phase structure显示文摘Global environmental concerns on the toxicity of lead-based piezoelectrics impel the great mass fervor on investigations of lead-free alternatives.Barium titanate(BaTiO3,BT)ceramics,the first discovered perovskite ferroelectrics,were widely employed to fabricate dielectric capacitors from 1950s.Since a piezoelectric breakthrough was achieved via chemical modification,intensive researches have been performed embracing lead-free BT-based piezoelectrics and their extensional functionalities.In this review,we encompass the stateof-the-art progress on chemical modification tuning phase structure toward advanced electrical properties in BT-based ceramics.Generally,modulated regularity of cations substitution on phase transition is summarized and clarified.Then,we highlight the common methodologies of phase structure(phase boundary,relaxor phase,room-temperature phase transition,etc.)design for optimizing piezoelectricity,electrostrictive strain,electrocaloric,dielectric energy storage or permittivity performances,and cover the noticeable developments and relevant physical mechanisms.Finally,perspectives and challenges on future research issues are featured.This review proposes to exert the significant guidance and service for material design of BT-based and other lead-free perovskite materials with superior functionalities. | Chunlin Zhao Yanli Huang Jiagang Wu | 2020 | InfoMat2020，2，6： | 9 |
| 3 | A novel STING agonist-adjuvanted pan-sarbecovirus vaccine elicits potent and durable neutralizing antibody and T cell responses in mice,rabbits and NHPs显示文摘The emergence of SARS-CoV-2 variants and potentially other highly pathogenic sarbecoviruses in the future highlights the need for pan-sarbecovirus vaccines.Here,we discovered a new STING agonist,CF501,and found that CF501-adjuvanted RBD-FC vaccine(CF501/RBD-FC)elicited significantly stronger neutralizing antibody(nAb)and T cell responses than Alum-and cGAMP-adjuvanted RBD-FC in mice.Vaccination of rabbits and rhesus macaques(nonhuman primates,NHPs)with CF501/RBD-FC elicited exceptionally potent nAb responses against SARS-CoV-2 and its nine variants and 41 S-mutants,SARS-CoV and bat SARSr-CoVs.CF501/RBD-FC-immunized hACE2-transgenic mice were almost completely protected against SARS-CoV-2 challenge,even 6 months after the initial immunization.NHPs immunized with a single dose of CF501/RBD-FC produced high titers of nAbs.The immunized macaques also exhibited durable humoral and cellular immune responses and showed remarkably reduced viral load in the upper and lower airways upon SARS-CoV-2 challenge even at 108 days post the final immunization.Thus,CF501/RBD-Fc can be further developed as a novel pan-sarbecovirus vaccine to combat current and future outbreaks of sarbecovirus diseases. | Zezhong Liu Jie Zhou Wei Xu Wei Deng Yanqun Wang Meiyu Wang Qian Wang Ming Hsieh Jingming Dong Xinling Wang Weijin Huang Lixiao Xing Miaoling He Chunlin Tao Youhua Xie Yilong Zhang Youchun Wang Jincun Zhao Zhenghong Yuan Chuan Qin Shibo Jiang Lu Lu | 2022 | Cell Research2022，32，3： | 5 |
| 4 | N-doped graphene and TiO_2 supported manganese and cerium oxides on low-temperature selective catalytic reduction of NO_x with NH_3显示文摘A series of N-doped graphene(NG)and TiO_2 supported MnO_x–CeO_2 catalysts were prepared prepared by a hydrothermal method.The catalysts with different molar ratios of Mn/Ce(6:1,10:1,15:1)were investigated for the low-temperature selective catalytic reduction(SCR)of NO_x with NH_3.The synthesized catalysts were characterized by HRTEM,SEM,XRD,BET,XPS,and NH_3-TPD technologies.The characterization results indicated that manganese and cerium oxide particles dispersed on the surface of the TiO_2–NG support uniformly,and that manganese and cerium oxides existed in different valences on the surface of the TiO_2–NG support.At Mn element loading of 8 wt%,MnO_x–CeO_2(10:1)/TiO_2–1%NG displayed superior activity and improved SO_(2 )resistance.On the basis of the catalyst characterization,excellent catalytic performance and SO_2 tolerance at low temperature were attributed to the high content of manganese with high oxidation valence,extensive oxidation of NO into NO_2 by CeO_2 and strong NO adsorption capacity,and electron transfer of N-doped graphene. | Chunlin ZHAO Yanxia WU Hailong LIANG Xi CHEN Jie TANG Xianzhong WANG | 2018 | Journal of Advanced Ceramics2018，7，3： | 5 |
| 5 | Robust Optimization of Municipal Solid Waste Collection and Transportation with Uncertain Waste Output: A Case Study显示文摘Garbage collection is an important issue in urban environmental management.With the increased awareness of urban residents regarding safety,environmental protection,and health in recent years,it is necessary to logically organize municipal solid waste collection and transportation routes while also considering economic and social benefits.This article focuses on the optimization of the waste transportation routes of garbage trucks.With the objective of minimizing transportation costs and maximizing resident satisfaction,we establish a robust optimization model for the multi-trip collection and transportation of municipal solid waste in an uncertain environment.Resident satisfaction is defined as the penalty cost against a time window constraint.The Bertsimas robust optimization method is applied to characterize the uncertainty,and the decision-making scheme of the receiving route is used to adapt to waste volume changes.We conduct a case study based on real-world data for municipal solid waste collection and transportation in the Dongcheng District of Beijing,China.The solution is validated using the CPLEX program,and the validity of the model is verified.In addition,a sensitivity analysis of related parameters is conducted to study the impacts of variations in work hour limits and time windows on the total cost and service levels,as well as their relationships with the level of robustness.This could help decision-makers make reasonable choices based on actual conditions and to balance reductions in total cost with service level improvements. | Sicheng Zhang Jianwen Zhang Zhiwei Zhao Chunlin Xin | 2022 | Journal of Systems Science and Systems Engineering2022，31，2： | 4 |
| 6 | Formation of uniform reduced graphene oxide films on modified PET substrates using drop-casting method显示文摘In this work,uniform reduced graphene oxide(RGO) films were formed on poly-(ethylene terephthalate)(PET) substrates using a simple drop-casting method.We investigated four types of substrates:unmodified PET,polydopamine-coated PET.carboxyl-group-modified PET,and alkyl-group-modified PET.Upon water evaporation,the surface of the polydopamine-modified PET substrates can interact with the reduced graphene oxide sheets to form flattened and continuous RGO films,which exhibit a sheet resistance of 21.75 kΩ/sq at 82%transmittance.The result indicates that the properties of the surface groups determined whether uniform and flattened RGO films could be formed on the substrates.Hence,we proposed a simple and effective way to produce transparent and conductive films in which the catechol unit exhibits a great effect on the deposition of uniform RGO films on PET substrates. | Chunlin Zhao Li Xing Junhui Xiang Lijie Cui JianbinJiao Huazheng Sai Zhenyou Li Fei Li | 2014 | Particuology2014，12，6： | 4 |
| 7 | Local melting mechanism and its effects on mechanical properties of friction spot welded joint for Al-Zn-Mg-Cu alloy显示文摘Local melting and the eutectic film and liquation crack formation mechanisms during friction spot welding(FSp W) of Al-Zn-Mg-Cu alloy were studied by both experiment and finite element simulation. Their effects on mechanical properties of the joint were examined. When the welding heat input was high, the peak temperature in the stir zone was higher than the incipient melting temperature of the Al-Zn-Mg-Cu alloy. This resulted in local melting along the grain boundaries in this zone. In the retreating stage of the welding process, the formed liquid phase was driven by the flowing plastic material and redistributed as a 'U-shaped' line in the stir zone. In the following cooling stage, this liquid phase transformed into eutectic films and liquation cracks. As a result, a new characteristic of 'U' line that consisted of eutectic films and liquation cracks is formed in the FSp W join. This 'U' line was located in the high stress region when the FSp W joint was loaded, thus it was adverse to the mechanical properties of the FSpW joint. During tensile shear tests, the 'U' line became a preferred crack propagation path, resulting in the occurrence of brittle fracture. | Yunqiang Zhao Chungui Wang Jizhong Li Jinhong Tan Chunlin Dong | 2018 | Journal of Materials Science & Technology2018，34，1： | 4 |
| 8 | Disordered Translocation is Hastening Local Extinction of the Chinese Giant Salamander显示文摘Biodiversity is declining globally by an unprecedented extinction rate.This is especially true for amphibians,accounting for 24.3%of all threatened vertebrates.As the largest extant amphibian species in the world,wild populations of the Chinese giant salamander(Genus Andrias)(CGS)have decreased dramatically because of overexploitation and habitat degradation.Translocation has become an important strategy for restoring threatened wild populations worldwide.However,disordered tra nsloca tion usually has negative effects on the native populations.We provide an overview of CGS translocation and show that disordered translocation can increase local population extinction.Nearly four times the estimated number of wild individuals have been released across China.There a re three types of translocation used for CGS,namely,reinforcement,reintroduction and ecological replacement,the last of which accounts for over one-third of translocations.Our genetic screening revealed that most released individuals were not from local populations,with one to four lineages detected in every release site(n=6).This disordered translocation can potentially reduce the genetic integrity of original populations.Hence,we suggest suspending current CGS translocation activities immediately,until more robust measures can be developed and implemented to improve the current translocation program,especially with respect to lineage identifica tion a nd the identifica tion of appropriate release sites. | Guocheng SHU Ping LIU Tian ZHAO Cheng LI Yinmeng HOU Chunlin ZHAO Jie WANG Xiaoxiao SHU Jiang CHANG Jianping JIANG Feng XIE | 2021 | Asian Herpetological Research2021，12，3： | 4 |
| 9 | Anomozamites(Bennettitales) from Middle Jurassic Haifanggou Formation,western Liaoning,China显示文摘The Middle Jurassic Hangfanggou Formation is well exposed in Shangsanjiao and Xiasanjiao villages area,Baimashi town of Huludao,western Liaoning,China.Recently,abundant fossil plants were collected from the Hangfanggou Formation.One new species,Anomozamites sanjiaocunensis sp.nov.(Bennettitales),is described in this study.This is the first report of the genus Anomozamites from the Haifanggou Formation based upon the leaf morphology and epidermal structures.The discovery of the new species extends significantly the stratigraphic and geographic distribution of Anomozamites in the Middle Jurassic.It also shows that Anomozamites was a common member of Bennettitales once lived in the Middle Jurassic warm temperate region.The new species also improves the knowledge on understanding the leaf morphology,epidermal features and the diversity of Anomozamites during the Middle Jurassic.The epidermal characters of the new species and its associated plants reveal that the plants grew in a warm and moderately humid environment in the warm temperate zone.The presence of some deciduous plants,such as ginkgoaleans,czekanowskialeans and conifers,indicate the climate with seasonal fluctuations in temperature. | ZHAO Miao SUN Chunlin David L.Dilcher ZHAO Zhe NA Yuling | 2015 | Global Geology2015，18，2： | 3 |
| 10 | Comprehensive identification and analyses of the Hsf gene family in the whole-genome of three Apiaceae species显示文摘Apiaceae is a major family from Apiales and includes many important vegetable and medicinal crops.Heat shock transcription factors(Hsf)play important roles in heat tolerance during plant development.Here,we conducted systematic analyses of the Hsf gene family in three Apiaceae species,including 17 Apium graveolens(celery),32 Coriandrum sativum(coriander),and 14 Daucus carota(carrot).A total of 73 Hsf genes were identified in three representative species,including Arabidopsis thaliana,Vitis vinifera,and Lactuca sativa.Whole-genome duplication played important roles in the Hsf gene family’s expansion within Apiaceae.Interestingly,we found that coriander had more Hsf genes than celery and carrot due to greater expansion and fewer losses.Twenty-seven branches of the phylogenetic tree underwent considerable positive selection in these Apiaceae species.We also explored the expression patterns of Hsf genes in three plant organs.Collectively,this study will serve as a rich gene resource for exploring the molecular mechanisms of heat tolerance.Additionally,this is the first study to report on the Hsf gene family in Apiaceae;thus,our research will provide guidance for future comparative and functional genomic studies on the Hsf gene family and others in Apiaceae. | Qiaoying Pei Tong Yu TongWu Qihang Yang Ke Gong Rong Zhou Chunlin Cui Ying Yu Wei Zhao Xi Kang Rui Cao Xiaoming Song | 2021 | Horticultural Plant Journal2021，7，5： | 3 |
| 11 | Adaptive ANCF method and its application in planar flexible cables显示文摘In the conventional absolute nodal coordinate formulation(ANCF), the model is pre-meshed, the number,distribution and type of elements are unchangeable during the simulation. In addition, the deformations of a flexible body are space-varying and time-varying, one cannot predict when, where, and how the deformations will occur. Therefore, in order to obtain a satisfactory accuracy during the whole simulation, the model is usually densely meshed, but it will result in a loss of computational efficiency. In this study,an adaptive absolute nodal coordinate formulation(AANCF)is proposed to optimize the accuracy and efficiency of flexible dynamics. The movement features of flexible bodies are analyzed, and the conventional and adaptive ANCF methods are compared. Then the adaptive computation strategy is presented. The discretization errors come from the inability of interpolation functions of individual elements to capture the complexity of the exact solution, so the mesh can be adaptively optimized by changing the element sizes or the orders of interpolation functions during dynamic computation. Important issues of AANCF, including error estimation,mesh updating, and performance of the AANCF model, are analyzed and discussed in detail. A theoretical model of a planar AANCF cable is presented, where the strategies of dividing and merging elements are discussed. Moreover, the continuity of dynamic variables is deduced, and the mean factors that affect the continuity are obtained, which is very important for the subsequent continuity optimization. Thesimulation results indicate that the distribution of elements varies with time and space, and the elements are denser in large-deformed domains. The AANCF model improved the computational accuracy and efficiency, but the system energy is discontinuous when the elements are merged. Therefore,a continuity-optimized AANCF model is given based on the previous continuity analysis, the results show that the accuracy and continuity of energy are further improved by the continuity-optimized AANCF model. | Yue Zhang Cheng Wei Yang Zhao Chunlin Tan Yongjian Liu | 2018 | Acta Mechanica Sinica2018，34，1： | 3 |
| 12 | Potassium sodium niobate based lead-free ceramic for high-frequency ultrasound transducer applications显示文摘The BiAlO_(3)(BA)and(Bi_(0.5)Na_(0.5))ZrO_(3)(BNZ)are selected to form a solid solution with(K_(0.48)Na_(0.52))NbO_(3) via traditional solid state technique to optimize the electrical performance and temperature stability of KNNbased lead-free ceramics,simultaneously.Here we show that doped BA has a great influence on phase structure,morphologies,and electrical properties.The XRD patterns and dielectric constant versus temperature curves reveal that an increase in the BA content results in a transform of phase structures from a coexistence state of rhombohedral,orthorhombic and tetragonal phases to pseudocubic phase.Owing to the construction of R-O-T phase boundary,optimized performances(T_(C)~336℃,d_(33)~306 pC/N,kp=0.48)are obtained in 0.962(K_(0.48)Na_(0.52))NbO_(3)-0.003BiAlO_(3)-0.035(Bi_(0.5)Na_(0.5))ZrO_(3)(KNN-3)ceramics.Based on the sintered KNN-3 ceramic samples,high-frequency ultrasound imaging transducers are designed and fabricated,which exhibits a high center frequency of 24.5 MHz,a broad -6 dB bandwidth of 97% and a high-sensitivity.Finally,the imaging characteristic of the lead-free transducers is demonstrated via ex vivo imaging of biological tissue structure.As environment friendly materials,the excellent electrical and acoustic performance of developed KNN-based ceramics has great potential for practical applications. | Jie Xing Laiming Jiang Chunlin Zhao Zhi Tan Qian Xu Jiagang Wu Qiang Chen Dingquan Xiao Jianguo Zhu | 2020 | Journal of Materiomics2020，6，3： | 3 |
| 13 | A prototype RF power source for CSNS/RCS显示文摘A prototype RF power source has been built to supply high RF power to a ferrite-loaded cavity, which is a part of R&D of the Rapid Cycling Synchrotron of China Spallation Neutron Source (CSNS/RCS). A direct fast RF feedback amplifier, a 4:1 impedance transformer and auto tuning grid were locally located to compensate the heavy beam loading of CSNS/RCS. Design and commissioning of the RF power source is discussed here, also with some advice on system improvement. | WeiLing Huang (1) Hong Sun (1) HaiQi Zhao (2) Yu Liu (2) YanDong Li (2) ZhiGuang Qiao (2) Xiao Li (1) ChunLin Zhang (1) | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，S2： | 3 |
| 14 | Metamaterials: Reshape and Rethink显示文摘Metamaterials are composite materials whose material properties(acoustic, electrical, magnetic, or optical, etc.) are determined by their constitutive structural materials, especially the unit cells. The development of metamaterials continues to redefine the boundaries of materials science. In the field of electromagnetic research and beyond, these materials offer excellent design flexibility with their customized properties and their tunability under external stimuli. In this paper, we first provide a literature review of metamaterials with a focus on the technology and its evolution. We then discuss steps in the industrialization process and share our own experience. | Ruopeng Liu Chunlin Ji Zhiya Zhao Tian Zhou | 2015 | Engineering2015，1，2： | 2 |
| 15 | XPS Studies of Magnetic Multilayers显示文摘NiOx/N81Fe19 and Co/AlOx/Co magnetic multilayers were fabricated by reactive RF/DC magnetron sputtering on clean glass substrates and oxidized Si (100) substrates, respectively. The exchange biasing field (Hex) between NiOx, and Ni81Fe19 as a function of NiOx, oxidation states was studied by X-ray photoelectron spectroscopy (XPS). The oxidation states and the oxide thickness of Al layers in magnetic multilayer films consisting of Co/AlOx/Co were also analyzed. It is found that the Hex of NiOx/Ni81Fe19 films only depends on Ni2+ but not on Ni3+ or Ni. The bottom Co can be completely covered by depositing an Al layer thicker than 2.0 nm. The oxide layer was Al2O3, and its thickness was 1.15 nm. | Guanghua Yu, Hongchen Zhao, Jiao Teng, Chunlin Chai, Fengwu Zhu, Yang Xia, Shumin Chai Material Science and Engineering School, University of Science and Technology Beijing, Beijing 100083, China Microelectronics Center, Chinese Academy of Science, Beijin | 2001 | Journal of University of Science and Technology Beijing2001，8，3： | 2 |
| 16 | Nestedness of waterbird assemblages in the subsidence wetlands recently created by underground coal mining显示文摘Nestedness has been a research focus in fields of island biogeography and community ecology in recent decades. Although nestedness of faunal assemblages has been investigated in natural wetlands, it remains largely unknown whether and why waterbird communities in artificial wetlands follow n ested patter ns. We exami ned the existence of n ested ness and un derlyi ng drivers in waterbird comm un ities in subside nee wetlands that are recently created by large-scale un derground coal mining in the North China Plain. Twelve point-count surveys for waterbirds were undertaken approximately every 2 weeks in 55 subside nee wetla nds from September 2016 to April 2017. We used the metric WNODF to estimate nestedness of the assemblages. Partial Spearman rank correlations were performed to examine the association between the nestedness and habitat variables (wetland area, landscape connectivity, wetland age, and habitat diversity) as well as life-history traits (body size, clutch size, dispersal ratio, geographical range size, and migrant status) related to species exti notion risk and colon izati on rate. Waterbird assemblages in the subside nee wetla nds were significantly nested. After controlling for other independent variables, the magnitude of nestedness was significantly and negatively correlated with wetland area and species trait linked to extinction risk (i.e., geographical range size). Our results indicate that selective extinction may be the main driver of the nestedness of waterbird assemblages in our study system. However, the nestedness was not due to passive sampling, selective colonization, or habitat diversity. From a conservation viewpoint, both large wetlands and waterbirds with a small geographic range should be protected to maximize the preserved species richness. | Chunlin LI Binbin ZHAO Yanping WANG | 2019 | Current Zoology2019，65，2： | 2 |
| 17 | Effect of boron addition on the microstructures and mechanical properties of thermomechanically processed and tempered low carbon bainitic steels显示文摘Thermomechanical process and tempering heat treatment were employed to produce the experimental steel plates. The effect of boron addition on the microstructure and mechanical properties of low carbon bainitic steels was studied in this paper. Microstructure observation and crystallographic features were conducted by using optical microscopy, SEM, TEM and electron back scattering diffraction (EBSD) analysis. The results showed that under the same rolling processes and heat treatment conditions, a substantial increase in strength is obtained by addition of boron into steel, but accompanied by an obvious drop in toughness. New martensite phase forms along the grain boundaries on tempering at 650 C mainly due to boron segregation, which can further deteriorate impact toughness of the boron bearing steel. The EBSD analysis showed that high angle grain boundary is not responsible for the deteriorated toughness of the boron bearing steel because it has relatively higher percentage of high angle grain boundary than the boron free steel. The low toughness of the boron bearing steel is mainly attributed to the coarse boride precipitated particles according to the results of fractograph observation. | Liangyun LAN Chunlin QIU Ping ZHOU Dewen ZHAO Canming LI Xiuhua GAO Linxiu DU | 2011 | Acta Metallurgica Sinica(English Letters)2011，24，6： | 2 |
| 18 | Towards Wide-Open, Adaptable DCF Implementation for Dynamic Networks显示文摘This work proposes a Field Programmable Gate Array (FPGA)-oriented architecture for the IEEE 802. 11 Distributed Coordination Function (DCF) transceiver. We describe the functional blocks carrying out the Carrier Sense Multiple Accesses with Collision Avoidance (CSMA/CA), develop the interfaces to the application layer and the physical layer, and implement it on FPGA devices by utilizing Very-high-speed-integrated-circuit Hardware Description Language (VHDL). The novelty of our proposal is twofold. Firstly, all MAC parameters (i.e., Max/Min Contention Window, Data Unit Length, Fragmentation Threshold, Retry Limit, etc.) can be directly accessed and programmed from the application layer interface, which is necessary to achieve better network performance in dynamic environments. Secondly, the character based on FPGA makes the proposal more flexible and risk-reduced for the development of DCF-based wireless networks, such as MANETs and software-defined-radio-based cognitive ad hoc networks. | Wang Shan Abdelhakim Hafid Zhao Haitao Huang Shengchun Xieng Chunlin Wei Jibo | 2012 | China Communications2012，9，7： | 2 |
| 19 | Hypoxia-Inducible Factor-1α C1772T Polymorphism and Cancer Risk: A Meta-Analysis Including 18,334 Subjects显示文摘 | Yanwei Ye Min Wang Shuang Hu Yingqiang Shi Xiefu Zhang Ye Zhou Chunlin Zhao Guojun Wang Jianguo Wen Hong Zong | 2014 | Cancer Investigation2014，，4： | 1 |
| 20 | Fat deposition deficiency is critical for the high mortality of pre-weanling newborn piglets显示文摘Background: The high mortality of pre-weanling piglets is a dominant challenge which severely restricts the development of pig industry. A number of factors including nutrients imbalance and temperature variation during postnatal period of piglets have been reported to closely associated with the high mortality of postnatal piglets.This study aims to find out the relationship between fat deposition and survival of newborn piglets.Results: There were no differences in organ coefficient and bone density between the surviving and dead piglets(P > 0.05). The body weight and the fat deposition in the dead piglets were lower than the live individuals(P < 0.05).Consistently, the average sizes of white adipocytes in back and abdominal adipose tissues of dead piglets were smaller than the survivals(P < 0.05). The protein expression levels of adipocyte differentiation markers PPARγ and C/EBPα in the back and abdominal adipose tissues were lower in dead piglets compared to live piglets. The mRNA expressions of thermogenic markers PGC1α and PRDM16 in adipose tissues were decreased in the dead piglets(P < 0.05). The microarray of back fat samples from the surviving and dead piglets were conducted; two down-regulated genes namely AAMDC and CASTOR1 were identified from the dead piglets. According to quantitative real-time PCR(RT-PCR) analysis, the mRNA expression of AAMDC decreased, whereas CASTOR1 expression elevated in the dead piglets compared to the surviving piglets(P < 0.05).Conclusions: The fat deposition and adipocyte differentiation in the dead piglets are insufficient compared to the surviving piglets, which may attenuate the thermogenic ability of white adipose tissue(WAT). Our data indicate that fat deposition in newborn piglets is vital to their survival. | Ting He Long He Enen Gao Jinhua Hu Jianjun Zang Chunlin Wang Jinshan Zhao Xi Ma | 2018 | Journal of Animal Science and Biotechnology2018，9，4： | 1 |
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