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| 1 | Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules显示文摘由病毒的 transduction 的四抄写因素 Oct4, Klf4, Sox2 和 c-Myc 的介绍能导致体的房间的 reprogramming 进导致的 pluripotent 干细胞(iPSCs ) ,但是 iPSCs 的使用被病毒的交货系统的使用妨碍。导致化学药品的 reprogramming 把一条新奇途径提供给没有任何病毒的基于向量的基因修正,产生 iPSCs。尽管,以前的报告证明几个小分子能代替一些 reprogramming 因素至少二个抄写因素, Oct4 和 Klf4,仍然被要求从老鼠产生 iPSCs 胚胎的成纤维细胞。这里,我们识别特定的化学联合,它是足够的面对一个单个抄写因素从胚胎的老鼠和成年成纤维细胞允许 reprogramming, Oct4 在 20 天以内,代替 Sox2, Klf4 和 c-Myc。用这个处理产生的 iPSCs 类似于胚胎的干细胞以全球基因表示介绍的老鼠,在 vitro 并且在 vivo 的 epigenetic 地位和 pluripotency。我们也发现那 8 天 Oct4 正式就职是足够的面对小分子启用导致 Oct4 的 reprogramming,它建议 reprogramming 在开始的 8 天以内被开始并且独立于连续外长的 Oct4 表示。没有基因修正,这些发现将帮助 iPSCs 的未来产生,以及阐明位于 reprogramming 过程下面的分子的机制。 | Yanqin Li Qiang Zhang Xiaolei Yin Weifeng Yang Yuanyuan Du Pingping Hou Jian Ge Chun Liu Weiqi Zhang Xu Zhang Yetao Wu Honggang Li Kang Liu Chen Wu Zhihua Song Yang Zhao Yan Shi Hongkui Deng | 2011 | Cell Research2011,21,1: | 51 |
| 2 | PM_(2.5) in an industrial district of Zhengzhou,China:Chemical composition and source apportionment显示文摘郑州是在中国的一个发展中的城市,那被微粒物质的高水平重重地弄脏。在这研究,好微粒物质(PM2.5 ) 在在 2010 的郑州的一个工业区域为他们的化学作文(可溶的离子,元素,元素的碳(EC ) 和器官的碳(OC )) 镇定、分析。分别地, PM2.5 的平均集中与 175 g/m3 的年度一般水准是 181, 122, 186 和 211 g/m3 春天,夏天,秋天和冬季了,远超过美国国家空气质量标准(15 g/m3 ) 的 PM2.5 规定。在郑州的 PM2.5 的主导的部件是第二等的离子(硫酸盐和硝酸盐) 和碳部分。可溶的离子,全部的碳和元素分别地贡献了 41% PM2.5 质量, 13% 和 3% 。土壤灰尘,第二等的喷雾器和煤燃烧,各贡献大约 26% 全部的 PM2.5 质量, 24% 和 23% ,是 PM2.5 的主要来源,根据积极矩阵因式分解分析的结果。生物资源烧的混合来源,油燃烧和焚化贡献了 13% PM2.5。从车辆和工业产生的好微粒物质分别地贡献了大约 10% PM2.5 和 4% 。 | Ningbo Geng Jia Wang Yifei Xu Wending Zhang Chun Chen Ruiqin Zhang | 2013 | Particuology2013,11,1: | 46 |
| 3 | Reprogramming of ovine adult fibroblasts to pluripotency via drug-inducible expression of defined factors显示文摘在 enucleated 鸡蛋的体的房间的 Reprogramming 做了多丽,绵羊,在 1996 的第一个成功地克隆的哺乳动物。然而,绵羊的机制体的房间 reprogramming 还没被探讨了。而且,绵羊胚胎的茎(ES ) 细胞仍然不是可得到的,它限制精确修改基因的绵羊的产生。在这研究,我们报导体的房间能是的那只绵羊直接 reprogrammed 到导致的 pluripotent 用定义因素(Oct4, Sox2, c-Myc, Klf4, Nanog, Lin28, SV40 大 T 和 hTERT ) 的茎(iPS ) 房间。我们的观察显示从绵羊的体的细胞比从另外的种,在 iPS,细胞被报导了的体的细胞对改编更困难。我们证明绵羊 iPS 房间表示 ES 房间标记,包括碱的磷酸酶, Oct4, Nanog, Sox2, Rex1,阶段特定的胚胎的 antigen-1, TRA-1-60, TRA-1-81 和 E-cadherin。绵羊 iPS 房间展出了正常 karyotypes 并且能在 vitro 并且在 teratomas 区分进所有三细菌层。我们的学习可以帮助在绵羊揭示体的房间 reprogramming 的机制并且提供一个平台为绵羊 ES 房间探索文化条件。而且,绵羊 iPS 房间可以直接被用来产生精确修改基因的绵羊。 | Lei Bao Lixiazi He Jijun Chen Zhao Wu Jing Liao Lmgdun Rao Jiangtao Ren Hui Li Hui Zhu Lei Qian Yijun Gu Huimin Dai Xun Xu Jinqiu Zhou Wen Wang Chun Cui Lei Xiao | 2011 | Cell Research2011,21,4: | 32 |
| 4 | The Association of Maternal Body Composition and Dietary Intake with the Risk of Gestational Diabetes Mellitus during the Second Trimester in a Cohort of Chinese Pregnant Women显示文摘Objective To investigate the association of maternal body composition and dietary intake with the risk of gestational diabetes mellitus(GDM). Methods A total 154 GDM subjects and 981 controls were enrolled in a prospective cohort study in 11 hospitals from May 20, 2012 to December 31, 2013. Bioelectrical impedance analysis and dietary surveys were used to determine body composition and to evaluate the intake of nutrients in subjects at 21-24 weeks' gestation(WG). Logistic regression analysis was applied to explore the relationships of maternal body composition and dietary intake with the risk of GDM morbidity. Results Age, pre-pregnant body weight(BW), and body mass index(BMI) were associated with increased risk of GDM. Fat mass(FM), fat mass percentage(FMP), extracellular water(ECW), BMI, BW, energy, protein, fat, and carbohydrates at 21-24 WG were associated with an increased risk of GDM. In contrast, fat free mass(FFM), muscular mass(MM), and intracellular water(ICW) were associated with a decreased risk of GDM. Conclusion Maternal body composition and dietary intake during the second trimester of pregnancy were associated with the risk of GDM morbidity. | Xu Qing Gao Zhi Ying Li Li Ming Wang Lu Zhang Qian Teng Yue Zhao Xia Ge Sheng Jing Hong Jiang Yang Yong Tao Liu Xiao Jun Lyu Chun Jian Mao Lun Yu Xiao Ming Liu Ying Hua Kong Ai Jing Yang Xue Yan Liu Zhao Zhang Yong Wang Jin Zhang Xin Sheng Xue Chang Yong Lu Yan Ping | 2016 | Biomedical and Environmental Sciences2016,29,1: | 29 |
| 5 | Indoor Allergen Levels and Household Distributions in Nine Cities Across China显示文摘Objective Chinese allergic subjects have high levels of sensitization to house dust mite(HDM) and other indoor allergens. This study quantifies common indoor allergen levels in Chinese households. Methods Dust samples were collected from nine cities. Major allergens Der p 1 and Der f 1 from Dermatophagoides pteronyssinus and D. farinae, and specific antigens of Blomia tropicalis, Tyrophagus putrescentiae, Acarus siro, and cockroach species Blattella germanica and Periplaneta americana were measured by ELISA. Results HDM allergens were found in dust samples from bedding in 95% of the Chinese households. The median levels varied from <0.006 to 9.2 μg/g of dust, depending on the city. The percentages of households having HDM allergen levels associated with the risk of developing allergy sensitization and asthma were 65% and 25%, respectively. Specific antigens of the storage mite and cockroach were only found in samples from the southern and tropical regions of China. Levels of mite allergens were generally higher in samples from bedding compared to samples from the living room, even for storage mites, whereas levels of cockroach antigens were higher in the living room samples. Conclusion HDM allergens are present in bedding dust samples from most Chinese households. Cities in southern and central China have relatively high levels of HDM major allergens compared to cities in northern and western China. Antigens of storage mites and cockroaches are not as common as HDM allergens. | ZHENG Yi Wu LAI Xu Xin ZHAO De Yu ZHANG Chun Qing CHEN Jian Jun ZHANG Luo WEI Qing Yu CHEN Shi LIU En Mei NORBACK Dan GJESING Birgitte ZHONG Nan Shan SPANGFORT D.Michael | 2015 | Biomedical and Environmental Sciences2015,28,10: | 24 |
| 6 | Role of adjuvant chemoradiotherapy in treatment of resectable esophageal carcinoma: a meta-analysis显示文摘 | ZHENG Bin ZHENG Wei ZHU Yong LIN Xiao-yan XU Ben-hua CHEN Chun | 2013 | Chinese Medical Journal2013,,6: | 22 |
| 7 | Development and application of biological technologies in fish genetic breeding显示文摘Fish genetic breeding is a process that remolds heritable traits to obtain neotype and improved varieties.For the purpose of genetic improvement,researchers can select for desirable genetic traits,integrate a suite of traits from different donors,or alter the innate genetic traits of a species.These improved varieties have,in many cases,facilitated the development of the aquaculture industry by lowering costs and increasing both quality and yield.In this review,we present the pertinent literatures and summarize the biological bases and application of selection breeding technologies(containing traditional selective breeding,molecular marker-assisted breeding,genome-wide selective breeding and breeding by controlling single-sex groups),integration breeding technologies(containing cross breeding,nuclear transplantation,germline stem cells and germ cells transplantation,artificial gynogenesis,artificial androgenesis and polyploid breeding)and modification breeding technologies(represented by transgenic breeding)in fish genetic breeding.Additionally,we discuss the progress our laboratory has made in the field of chromosomal ploidy breeding of fish,including distant hybridization,gynogenesis,and androgenesis.Finally,we systematically summarize the research status and known problems associated with each technology. | XU Kang DUAN Wei XIAO Jun TAO Min ZHANG Chun LIU Yun LIU ShaoJun | 2015 | Science China(Life Sciences)2015,58,2: | 23 |
| 8 | Electroacupuncture reduces apoptotic index and inhibits p38 mitogen-activated protein kinase signaling pathway in the hippocampus of rats with cerebral ischemia/reperfusion injury显示文摘Electroacupuncture attenuates cerebral hypoxia and neuronal apoptosis induced by cerebral ischemia/reperfusion injury.To further identify the involved mechanisms,we assumed that electroacupuncture used to treat cerebral ischemia/reperfusion injury was associated with the p38 mitogen-activated protein kinase(MAPK) signaling pathway.We established rat models of cerebral ischemia/reperfusion injury using the modified Zea-Longa's method.At 30 minutes before model establishment,p38 MAPK blocker SB20358 was injected into the left lateral ventricles.At 1.5 hours after model establishment,electroacupuncture was administered at acupoints of Chize(LU5),Hegu(LI4),Zusanli(ST36),and Sanyinjiao(SP6) for 20 minutes in the affected side.Results showed that the combination of EA and SB20358 injection significantly decreased neurologic impairment scores,but no significant differences were determined among different interventional groups.Hematoxylin-eosin staining also showed reduced brain tissue injuries.Compared with the SB20358 group,the cells were regularly arranged,the structures were complete,and the number of viable neurons was higher in the SB20358 + electroacupuncture group.Terminal deoxynucleotidyl transferase(Td T)-mediated d UTP nick-end labeling assay showed a decreased apoptotic index in each group,with a significant decrease in the SB20358 + electroacupuncture group.Immunohistochemistry revealed reduced phosphorylated p38 expression at 3 days in the electroacupuncture group and SB20358 + electroacupuncture group compared with the ischemia/reperfusion group.There was no significant difference in phosphorylated p38 expression between the ischemia/reperfusion group and SB20358 group.These findings confirmed that the electroacupuncture effects on mitigating cerebral ischemia/reperfusion injury are possibly associated with the p38 MAPK signaling pathway.A time period of 3 days could promote the repair of ischemic cerebral nerves. | Xiao Lan Xin Zhang Guo-ping Zhou Chun-xiao Wu Chun Li Xiu-hong Xu | 2017 | Neural Regeneration Research2017,12,3: | 18 |
| 9 | Laparoscopic radical cystectomy with orthotopic ileal neobladder in the female: report of 14 cases显示文摘背景膀胱癌是在中国的最普通的恶意的 urological 肿瘤。我们在场我们有在有到 2008 年 2月的从2003年2月的膀胱 carcinoma.Methods 的女病人的 orthotopic ileal neobladder 的 laparoscopic 激进分子囊切除术(纵向冗余码校验)的初步的经验和结果,有膀胱癌的 14 个女病人与 orthotopic ileal neobladder 经历了纵向冗余码校验。九个这些病人经历了子宫切除和卵巢切除术,和子宫和卵巢的附器的另外的 5 有的保藏。当需要时,标准双边的骨盆的 lymphadenectomy 被与子宫切除和卵巢切除术 laparoscopically 被完成的激进的囊切除术跟随。肿瘤被一 4-5 厘米移开更低的中线腹的切口,由 ileal neobladder 和 ureter-neobladder 的身体外的吻合的构造列在后面。neobladder 在在 14 个病人的吝啬的起作用的时间和血损失是的 laparoscope.Results 下面被吻合到尿道的树桩 350.2 分钟和 349.8 ml, respectively.Postoperative 复杂并发症在 1 个病人在 1 耐心、小袋阴道的管包括了 uretero 小袋 anastomotic 苛评。所有病人的后续时间从 3 ~ 60 个月,并且 12 个病人被跟随在上面为半年里的超过 6 个月和完成的频尿。一耐心的有的偶尔的白天尿不能自制和 2 有的夜间不能自制。经历了 hystectomy 和卵巢切除术的二个病人在一年以后有 voiding 困难,它被断断续续的 self-catheterization 对待。neobladder 和剩余尿的吝啬的体积分别地是 333.6 ml 和 31.2 ml。外科的边缘是为所有病人免费的肿瘤。一个病人有骨头转移并且死在有在女病人的 orthotopic ileal neobladder 的 operation.Conclusions 纵向冗余码校验以后的 11 个月是有低病态和可接受的 neobladder 功能的一个技术上可行、安全、微型侵略的过程。长期的后续被要求证实 neobladder 功能和 oncological 结果。 | LIN Tian-xin ZHANG Cai-xia XU Ke-wei HUANG Hai JIANG Chun HAN Jin-li YAO You-sheng GUO Zheng-hui XIE Wen-lian YIN Xin-bao HUANG Jian | 2008 | Chinese Medical Journal2008,,10: | 18 |
| 10 | Inhibitory effects of Curcuma aromatica oil on proliferation of hepatoma in mice显示文摘AIM To reveal the inhibitory effects ofCurcuma aromatica oil(CAO)on cellproliferation of hepatoma in mice.METHODS Two tumor inhibitory experimentsof CAO on hepatoma in mice were conducted.The inhibitory effects of CAO on proliferation ofhepatoma in mice were evaluated by DNA imagecytometry and immunohistochemical staining ofproliferating cell nuclear antigen(PCNA).RESULTS The tumor inhibitory rates of CAOwere 52% and 51% in two experiments,respectively.Compared with those of the saline-treated control groups,both differences werestatistically significant(P<0.01).In the groupof mice treated with CAO,the cellular nuclearDNA OD value(249±70),areas(623 μm^2±228 μm^2)and DNA(2.38±0.67)index of hepaticcarcinomas were significantly lower than thoseof the control group(430±160,1073 μm^2±101 μm^2 and 4.48±0.71).CAO also couldincrease diploidy cell rates(29.00%±9.34% vs2.97%±5.69%,P<0.01)and decreasepentaploidy cell exceeding rate(30.04%±15.10% vs 70.89%±14.94%,P<0.01).In thegroup of mice treated with CAO,the labelingindexes of proliferating cell nuclear antigen (PCNA-LI)were 30%±4%,which weresignificantly lower than 40%±6% of the controlgroup(P<0.01).CONCLUSION The inhibition of CAO on thegrowth of hepatoma in mice might be associatedwith its depression on cellular proliferativeactivity. | Wan Yin Wu Qin Xu Ling Chun Shi Wei Bin Zhang | 2000 | World Journal of Gastroenterology2000,6,2: | 16 |
| 11 | An efficient method to synthesize HMX by nitrolysis of DPT with N_2O_5 and a novel ionic liquid显示文摘A novel polyethylene glycol(PEG)-200-based dicationic acidic ionic liquid(PEG_(200)-DAIL) was used to synthesize HMX from DPT by nitrolysis with N_2O_5.It was found that either N_2O_5 or PEG_(200)-DAIL could improve the yield.Furthermore,the combined use of PEG_(200)-DAIL and N_2O_5 could increase the yield of HMX to 64%with the used quantity of HNO_3 decreased dramatically. | Hui Zhen Zhi Jun Luo Guang An Feng Chun Xu Lv | 2009 | Chinese Chemical Letters2009,20,4: | 15 |
| 12 | Carbon carry capacity and carbon sequestration potential in China based on an integrated analysis of mature forest biomass显示文摘Forests play an important role in acting as a carbon sink of terrestrial ecosystem.Although global forests have huge carbon carrying capacity(CCC)and carbon sequestration potential(CSP),there were few quantification reports on Chinese forests.We collected and compiled a forest biomass dataset of China,a total of 5841 sites,based on forest inventory and literature search results.From the dataset we extracted 338 sites with forests aged over 80 years,a threshold for defining mature forest,to establish the mature forest biomass dataset.After analyzing the spatial pattern of the carbon density of Chinese mature forests and its controlling factors,we used carbon density of mature forests as the reference level,and conservatively estimated the CCC of the forests in China by interpolation methods of Regression Kriging,Inverse Distance Weighted and Partial Thin Plate Smoothing Spline.Combining with the sixth National Forest Resources Inventory,we also estimated the forest CSP.The results revealed positive relationships between carbon density of mature forests and temperature,precipitation and stand age,and the horizontal and elevational patterns of carbon density of mature forests can be well predicted by temperature and precipitation.The total CCC and CSP of the existing forests are 19.87 and 13.86 Pg C,respectively.Subtropical forests would have more CCC and CSP than other biomes.Consequently,relying on forests to uptake carbon by decreasing disturbance on forests would be an alternative approach for mitigating greenhouse gas concentration effects besides afforestation and reforestation. | LIU Ying Chun YU Gui Rui WANG Qiu Feng ZHANG Yang Jian XU Ze Hong | 2014 | Science China(Life Sciences)2014,57,12: | 15 |
| 13 | Pairing of integrins with ECM proteins determines migrasome formation显示文摘 | Danni Wu Yue Xu Tianlun Ding Yan Zu Chun Yang Li Yu | 2017 | Cell Research2017,27,11: | 14 |
| 14 | Effects of Cypermethrin on Male Reproductive System in Adult Rats显示文摘Objective To evaluate effects of cypermethrin on the testis histology and testosterone, LH and FSH in adult male Sprague‐Dawley rats. Methods The intact adult male rats were randomly divided into five groups and were treated with cypermethrin at doses of 0, 7.5, 15, 30, or 60 mg/kg per day by oral gavage for 15‐days. After the treatments, serum was collected for hormone assays. The testes, epididymides, seminal vesicles, and prostates were excised and weighed. The right testis was frozen for daily sperm production and the left one was processed for histopathology. Results Daily sperm production decreased significantly in 30 and 60 mg/(kg day) groups. Testicular structure abnormalities included atrophic and distorted seminiferous tubules, deformed and disordered arrangement of germ cells, reduced germ cells, Sertoli cells and Leydig cells, vacuolization and multinucleated formations of spermatids in the cypermethrin‐treated rats. Vacuolization was found in Sertoli cells and the deformed nucleus was noted in Leydig cells. Serum testosterone reduced significantly in 30 and 60 mg/(kg day) groups. Serum FSH increased significantly in 60 mg/(kg day) group. Conclusion Cypermethrin induces impairments of the seminiferous tubules structure and spermatogenesis in the rats. The damages of the male reproductive system may be attributed to the imbalance of circulating testosterone. | LI Yan Fang PAN Chen HU Jin Xia LI Jing XU Li Chun | 2013 | Biomedical and Environmental Sciences2013,26,3: | 13 |
| 15 | Role of Fas/FasL Pathway-mediated Alveolar Macrophages Releasing Inflammatory Cytokines in Human Silicosis显示文摘The role of Fas/Fas ligand (FasL) in mediating alveolar macrophage (AM)-derived inflammatory cytokines in 29 human lung silicosis patients and 6 controls was studied.It showed that the serum levels of IL-1β,TNF-α,IL-8,MIP-1α,MCP-1,and TGF-β1were higher in silicosis patients than in controls,and increased with the progression of silicosis except TGF-β1 and IL-8.TGF-β1,IL-8,MCP-1,MIP-1αwere efficiently down-regulated by anti-FasL antibody or caspase-8 inhibitor,indicating that Fas/FasL signaling promotes the | YAO San Qiao HE Qin Cheng YUAN Ju Xiang CHEN Jie CHEN Gang LU Yao BAI Yu Ping ZHANG Chun Min YUAN Yang XU Ying Jun | 2013 | Biomedical and Environmental Sciences2013,26,11: | 13 |
| 16 | In vitro differentiation of rat embryonic stem cells into functional cardiomyocytes显示文摘在老鼠的产生的最近的突破胚胎的干细胞(rESCs ) 打开门到基因指向为人的疾病的学习创造模型的申请。另外,在里面从进三细菌层的衍生物的 rESCs 的 vitro 区别系统将为哺乳动物的开发,房间函数,织物修理,和药发现的调查用作一个强大的工具和资源。然而,这些使用被困难限制了在 vitro 区别。这研究的目的是建立一在里面从 rESCs 并且到的 vitro 区别系统调查 rESCs 是否能够形成区分终端的 cardiomyocytes。用最新确定的 rESCs,我们发现那胚胎植物或动物身体(EB ) 基于在没能为没有浆液的栽培 rESCs 工作的老鼠转换字符(mESC ) 区别使用的方法。我们然后由三个化学禁止者和喂调节媒介的联合开发了一个协议。在这个条件下面, rESCs 变成了 EB,宣传并且区分三胚胎的细菌层。而且,形成 rESC 的 EB 能区分进自发地在 plating 以后打败 cardiomyocytes。分子、结构、功能的性质的分析表明导出 rESC 的 cardiomyocytes 类似于从胎儿的老鼠心和 mESCs 导出的那些。在结论,我们成功地发展了一在里面为功能的 myocytes 通过被产生并且显示老鼠的显型的 rESCs 的 vitro 区别系统胎儿的 cardiomyocytes。这个唯一的细胞的系统将提供一条新途径学习早开发和心脏的功能,并且在测试的药理学和房间治疗用作一个重要工具。 | Nan Cao Jing Liao Zumei Liu Wenmin Zhu Jia Wang Lijun Liu Lili Yu Ping Xu Chun Cui Lei Xiao Huang-Tian Yang | 2011 | Cell Research2011,21,9: | 13 |
| 17 | Relationship Between Serum DNA Replication, Clinicopathological Characteristics and Prognosis of Hepatitis B Virus-associated Glomerulonephritis with Severe Proteinuria by Lamivudine Plus Adefovir Dipivoxil Combination Therapy显示文摘Objective To explore the relationship between HBV DNA and the clinical manifestations, pathological types, injury severity, and prognosis with HBV-GN. Methods 102 patients with HBV-GN were divided into 3 groups, according to the serum titer of the HBV DNA. 24-h urine protein excretion, and other parameters were measured. Renal biopsy were performed. The association between HBV DNA and the pathological stage of membranous nephropathy was analyzed in 78 patients with HBV-MN. 24-h urine protein excretion was used for the evaluation of the prognosis, and the relationship between HBV DNA and prognosis were analyzed. Results Several findings were demonstrated with the increase of serum HBV DNA: 24-h urine protein excretion, plasma cholesterol, and triglycerides increased significantly(P<0.05), while the plasma level of albumin decreased significantly(P<0.05); The changes of serum creatinine, C3 and C4 were found but no statistical significance. Glomerular deposition of HBVAg increased, and the pathological injury was more severe. The clinical remission rate was lower in the high replication group after treatment as compared with the low replication group(P<0.01). Conclusion With the increase of serum HBV DNA, the urine protein excretion and the kidney injury were more severe, and the clinical remission rate was decreased. | JIANG Wei LIU Tuo DONG Hui XU Yan LIU Li Qiu GUAN Guang Ju LIU Xiang Chun | 2015 | Biomedical and Environmental Sciences2015,28,3: | 13 |
| 18 | Mass elevation effect and its forcing on timberline altitude显示文摘集体举起效果的概念(massenerhebungseffect, MEE ) 被 A 介绍。de Quervain 大约 100 年以前排队为象树那样的温度相关的参数说明观察趋势并且比在他们的外部边缘上在中央阿尔卑斯山脉发生在更高的举起的 snowline。它广泛地也在世界的另外的区域被观察了,但是没有重要,更不用说量,关于这现象的研究。特别,它完全通常在开发树带界线举起的恰当的模型被忽视了,与仅仅看作影响因素的经度或纬度。这篇论文试着确定到树带界线的 MEE 的贡献举起。认为更多广泛陆地团并且特别越高在陆地质量的内部的山底,越 greater 集体举起效果,这篇论文作为 MEE 的大小拿山底举起(MBE ) 。我们收集树带界线举起的 157 个数据点,并且把他们的纬度,经度和 MBE 用作独立变量在东南的欧亚的大陆为树带界线举起造一个多重线性回归方程。结果生产到树带界线高度活动范围 25.11% , 29.43% ,和 45.46% 的纬度,经度和 MBE 的贡献分别地。北纬度的诺思 | HAN Fang YAO Yonghui DAI Shibao WANG Chun SUN Ranhao XU Juan ZHANG Baiping | 2012 | Journal of Geographical Sciences2012,22,4: | 12 |
| 19 | Path planning and stability control of collision avoidance system based on active front steering显示文摘Vehicle collision avoidance system is a kind of auxiliary driving system based on vehicle active safety,which can assist the driver to take the initiative to avoid obstacles under certain conditions,so as to effectively improve the driving safety of vehicle.This paper presents a collision avoidance system for an autonomous vehicle based on an active front steering,which mainly consists of a path planner and a robust tracking controller.A path planner is designed based on polynomial parameterization optimized by simulated annealing algorithm,which plans an evasive trajectory to bypass the obstacle and avoid crashes.The dynamic models of the AFS system,vehicle as well as the driver model are established,and based on these,a robust tracking controller is proposed,which controls the system to resist external disturbances and work in accordance with the planning trajectory.The proposed collision avoidance system is testified through CarSim and Simulink combined simulation platform.The simulation results show that it can effectively track the planning trajectory,and improve the steering stability and anti-interference performance of the vehicle. | WNAG Chun Yan ZHAO WanZhong XU ZhiJiang ZHOU Guan | 2017 | Science China(Technological Sciences)2017,60,8: | 12 |
| 20 | Chang'E-1 Lunar Mission:An Overview and Primary Science Results显示文摘Chang'E-1 is the first lunar mission in China,which was successfully launched on Oct.24th,2007.It was guided to crash on the Moon on March 1,2009,at 52.36°E,1.50°S,in the north of Mare Fecunditatis.The total mission lasted 495 days,exceeding the designed life-span about four months.1.37Terabytes raw data was received from Chang'E-1.It was then processed into 4Terabytes science data at different levels.A series of science results have been achieved by analyzing and applicating these data,especially 'global image of the Moon of China's first lunar exploration mission'.Four scientific goals of Chang'E-1 have been achieved.It provides abundant materials for the research of lunar sciences and cosmochemistry.Meanwhile these results will serve for China's future lunar missions. | Ouyang Ziyuan Li Chunlai Lu Chang Liu Jianzhong Zou Yongliao Zhang Hongbo Jianjun Zuo Wei Su Yah Wen Weibin Bian Wei Zhao Baochang Wang Jianyu Yang Jianfeng Chang Jin Wang Huanyu Zhang Xiaohui Wang Shijin Wang Min Ren Xin Mu Lingli Kong Deqing Wang Xiaoqian Wang Fang Geng Liang Zhang Zhoubin Zheng Lei Zhu Xinying Zheng Yongchun Li Junduo Zou Xiaoduan Xu Chun Shi Shuobiao Gao Yifei Gao Guannan | 2010 | 空间科学学报2010,30,5: | 11 |