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| 1 | Effects of rock dusting in preventing and reducing intensity of coal mine explosions显示文摘 | Yi Luo Deming Wang Jianwei Cheng | 2017 | International Journal of Coal Science & Technology2017,4,2: | 11 |
| 2 | Existence of Classical Solutions to a Stationary Simplified Quantum Energy-Transport Model in 1-Dimensional Space显示文摘The existence of classical solutions to a stationary simplified quantum energytransport model for semiconductor devices in 1-dimensional space is proved.The model consists of a nonlinear elliptic third-order equation for the electron density,including a temperature derivative,an elliptic nonlinear heat equation for the electron temperature,and the Poisson equation for the electric potential.The proof is based on an exponential variable transformation and the Leray-Schauder fixed-point theorem. | Jianwei DONG Youlin ZHANG Shaohua CHENG | 2013 | Chinese Annals of Mathematics,Series B2013,34,5: | 9 |
| 3 | Chemical characteristics of size-resolved aerosols in winter in Beijing显示文摘Size-resolved aerosols were continuously collected by a Nano Sampler for 13 days at an urban site in Beijing during winter 2012 to measure the chemical composition of ambient aerosol particles. Data collected by the Nano Sampler and an ACSM(Aerodyne Aerosol Chemical Speciation Monitor) were compared. Between the data sets,similar trends and strong correlations were observed,demonstrating the validity of the Nano Sampler. PM10 and PM2.5concentrations during the measurement were 150.5 ± 96.0 μg/m3(mean ± standard variation)and 106.9 ± 71.6 μg/m3,respectively. The PM2.5/PM10 ratio was 0.70 ± 0.10,indicating that PM2.5dominated PM10. The aerosol size distributions showed that three size bins of 0.5–1,1–2.5 and 2.5–10 μm contributed 21.8%,23.3% and 26.0% to the total mass concentration(TMC),respectively. OM(organic matter) and SIA(secondary ionic aerosol,mainly SO42-,NO3-and NH4+) were major components of PM2.5. Secondary compounds(SIA and secondary organic carbon) accounted for half of TMC(about 49.8%) in PM2.5,and suggested that secondary aerosols significantly contributed to the serious particulate matter pollution observed in winter. Coal burning,biomass combustion,vehicle emissions and SIA were found to be the main sources of PM2.5. Mass concentrations of water-soluble ions and undetected materials,as well as their fractions in TMC,strikingly increased with deteriorating particle pollution conditions,while OM and EC(elemental carbon) exhibited different variations,with mass concentrations slightly increasing but fractions in TMC decreasing. | Kang Sun Yu Qu Qiong Wu Tingting Han Jianwei Gu Jingjing Zhao Yele Sun Qi Jiang Ziqi Gao Min Hu Yuanhang Zhang Keding Lu Stephan Nordmann Yafang Cheng Li Hou Hui Ge Masami Furuuchi Mitsuhiko Hata Xingang Liu | 2014 | Journal of Environmental Sciences2014,26,8: | 9 |
| 4 | Experimental study on the goaf flow field of the ‘‘U+I” type ventilation system for a comprehensive mechanized mining face显示文摘‘‘U' and ‘‘U+I' type ventilation experiments were performed on a three-dimensional fully mechanized caving face simulation experimental platform. The distribution laws of the pressure field and gas field in the mine goaf were obtained. Results show that the flow field in the goaf is generally asymmetric;the location of the gas accumulation area changes with ventilation parameters and can be used as an evaluation indicator to study the air leakage extent in the goaf. Hence, drainage pipes buried in the goaf to intensively extract gas can be designed in such gas areas, which can give considerations in both improving gas drainage efficiency and reducing air leakage. By comparing the gas extraction effect of model experiments with that of on-site underground practices, the basic laws are commonly consistent according to comparative analysis. Thus the experimental results can be used to guide the application of underground gas prevention and control. | Yu Zhaoyang Yang Shengqiang Qin Yi Hu Xincheng Cheng Jianwei | 2015 | International Journal of Mining Science and Technology2015,25,6: | 8 |
| 5 | Daytime HONO formation in the suburban area of the megacity Beijing, China显示文摘Nitrous acid(HONO),as a primary precursor of OH radicals,has been considered one of the most important nitrogencontaining species in the atmosphere.Up to 30%of primary OH radical production is attributed to the photolysis of HONO.However,the major HONO formation mechanisms are still under discussion.During the Campaigns of Air Quality Research in Beijing and Surrounding Region(CAREBeijing2006)campaign,comprehensive measurements were carried out in the megacity Beijing,where the chemical budget of HONO was fully constrained.The average diurnal HONO concentration varied from 0.33 to 1.2 ppbv.The net OH production rate from HONO,POH(HONO)net,was on average(from 05:00 to 19:00)7.1×106 molecule/(cm3 s),2.7 times higher than from O3 photolysis.This production rate demonstrates the important role of HONO in the atmospheric chemistry of megacity Beijing.An unknown HONO source(Punknown)with an average of 7.3×106molecule/(cm3 s)was derived from the budget analysis during daytime.Punknown provided four times more HONO than the reaction of NO with OH did.The diurnal variation of Punknown showed an apparent photo-enhanced feature with a maximum around 12:00,which was consistent with previous studies at forest and rural sites.Laboratory studies proposed new mechanisms to recruit NO2 and J(NO2)in order to explain a photo-enhancement of of Punknown.In this study,these mechanisms were validated against the observation-constraint Punknown.The reaction of exited NO2 accounted for only 6%of Punknown,and Punknown poorly correlated with[NO2](R=0.26)and J(NO2)[NO2](R=0.35).These results challenged the role of NO2 as a major precursor of the missing HONO source. | YANG Qiang SU Hang LI Xin CHENG YaFang LU KeDing CHENG Peng GU JianWei GUO Song HU Min ZENG LiMin ZHU Tong ZHANG YuanHang | 2014 | Science China Chemistry2014,57,7: | 8 |
| 6 | Shaking table experimental study of recycled concrete frame-shear wall structures显示文摘In this study, four 1/5 scaled shaking table tests were conducted to investigate the seismic performance of recycled concrete frame-shear wall structures with different recycled aggregates replacement rates and concealed bracing detail. The four tested structures included one normal concrete model, one recycled coarse aggregate concrete model, and two recycled coarse and fi ne aggregate concrete models with or without concealed bracings inside the shear walls. The dynamic characteristics, dynamic response and failure mode of each model were compared and analyzed. Finite element models were also developed and nonlinear time-history response analysis was conducted. The test and analysis results show that the seismic performance of the recycled coarse aggregate concrete frame-shear wall structure is slightly worse than the normal concrete structure. The seismic resistance capacity of the recycled concrete frame-shear wall structure can be greatly improved by setting up concealed bracings inside the walls. With appropriate design, the recycled coarse aggregate concrete frame-shear wall structure and recycled concrete structure with concealed bracings inside the walls can be applied in buildings. | Zhang Jianwei Cao Wanlin Meng Shaobin Yu Cheng Dong Hongying | 2014 | Earthquake Engineering and Engineering Vibration2014,13,2: | 8 |
| 7 | Effects of drought stress on photosynthesis and chlorophyll fluorescence images of soybean(Glycine max)seedlings显示文摘The main purpose of this research is to provide a theoretical foundation for the screening of drought-resistant soybean varieties and to establish an efficient method to detect the PSII actual photochemical quantum yields efficiently.Three soybean varieties were compared in this experiment after 15 d when they were planted in a greenhouse.These varieties were then exposed to light drought stress(LD)and serious drought stress(SD)conditions.With five times’measurement,chlorophyll fluorescence and soil-plant analysis development considered as the main basis for this study.Several parameters in SD conditions significantly reduced,such as net photosynthetic rates(Pn),stomatal conductance(Gs),PSII primary light energy conversion efficiency(Fv/FM),PSII actual photochemical quantum yields[Y(II)],photochemical quenching coefficient(qP)and non-photochemical quenching coefficient(qN).The soybeans in the seedling stage adapted to the inhibitory effect of drought stress on photosynthesis through stomatal limitation.Under serious drought stress,non-stomatal limitation damaged the plant photosynthetic system.The amplitudes of Pn and Y(II)of drought-resistant Qihuang 35 were lower than those of the two other varieties.Based on the data of this study,a new method had been developed to detect Y(II)which reflected the photosynthetic capacity of plant,R=0.85989,u=0.048803 when using multiple linear regression,and R=0.84285,u=0.054739 when using partial least square regression. | Wensen Wang Cheng Wang Dayu Pan Yakun Zhang Bin Luo Jianwei Ji | 2018 | International Journal of Agricultural and Biological Engineering2018,11,2: | 7 |
| 8 | Analysis of 100 consecutive cases of resectable pancreatic neuroendocrine neoplasms: clinicopathological characteristics and long-term outcomes显示文摘 | Yugang Cheng Hanxiang Zhan Lei Wang Jianwei Xu Guangyong Zhang Zongli Zhang Sanyuan Hu | 2016 | Frontiers of Medicine2016,10,4: | 5 |
| 9 | Modified Frequency Scaling Algorithm for FMCW SAR Data Processing显示文摘这份报纸论述放大算法的修改频率因为频率调制了连续波浪合成的孔雷达(FMCW SAR ) 数据处理。在在 FMCW SAR 的雷达和目标之间的相对运动将在收到的信号在接收期间并且在传播和接收之间介绍严肃的膨胀。膨胀能用常规信号处理方法在重建的图象引起严肃的失真。收到的信号被导出,在 range-Doppler 领域的收到的信号被给。在源于天线运动和方位角频率的阶段之间的关系被分析。放大算法的修改频率被建议与严肃的膨胀处理收到的信号。算法能有效地消除膨胀的影响。算法表演被模拟结果显示出。 | Jiang Zhihong Huang Fukan Wan Jianwei Cheng Zhu | 2007 | Chinese Journal of Aeronautics2007,20,4: | 5 |
| 10 | Postnatal feeding with high-fat diet induces obesity and precocious puberty in C57BL/6J mouse pups: a novel model of obesity and puberty显示文摘童年肥胖和肥胖相关的新陈代谢的复杂并发症被一本高脂肪的出生后的食谱导致。然而,一个合适的动物模型的缺乏在肥胖研究仍然是可观的挑战。在当前的学习,我们在断奶以后在哺乳期间并且到小狗提供了高脂肪的饮食(HFD ) 给水坝。我们也与导致 HFD 的出生后的肥胖开发了 C57BL/6J 老鼠小狗的一个新奇模型。结果证明用 HFD 喂在小狗导致胖免职和肥胖。而且, HFD 更 potently 比女小狗增加了男性的身体重量(BW ) 。喂 HFD 的女小狗是肥胖的,经历了早熟的发身,并且显示出在视下丘的增加的 kisspeptin 表示。然而,父母肥胖和早熟的发身没在导致 HFD 的出生后的重量获得和小狗的发身发作上施加 synergistic 效果。有趣地,有正常 BW 的一些喂 HFD 的崽也展出了早熟的发身。这发现建议了那篇食谱作文然而并非 BW 扳机发身发作。我们的模型建议肥胖和早熟的发身的好构造有效性。而且,我们的模型能也被用来探索在 dietinduced 之间的相互的相互作用出生后的童年肥胖和发身。 | Rahim Ullah Yan Su Yi Shen Chunlu Li Xiaoqin Xu Jianwei Zhang Ke Huang Naveed Rauf Yang He Jingjing Cheng Huaping Qin Yu-Dong Zhou Junfen Fu | 2017 | Frontiers of Medicine2017,11,2: | 5 |
| 11 | Temperature-induced Lifshitz transition in topological insulator candidate HfTe_5显示文摘The ongoing discoveries and studies of novel topological quantum materials have become an emergent and important field of condensed matter physics.Recently,HfTe_5 ignited renewed interest as a candidate of a novel topological material.The single-layer HfTe_5 is predicted to be a two-dimensional large band gap topological insulator and can be stacked into a bulk that may host a temperature-driven topological phase transition.Historically,HfTe_5 attracted considerable interest for its anomalous transport properties characterized by a peculiar resistivity peak accompanied by a sign reversal carrier type.The origin of the transport anomaly remains under a hot debate.Here we report the first high-resolution laser-based angle-resolved photoemission measurements on the temperature-dependent electronic structure in HfTe_5.Our results indicated that a temperature-induced Lifshitz transition occurs in HfTe_5,which provides a natural understanding on the origin of the transport anomaly in HfTe_5.In addition,our observations suggest that HfTe_5 is a weak topological insulator that is located at the phase boundary between weak and strong topological insulators at very low temperature. | Yan Zhang Chenlu Wang Guodong Liu Aiji Liang Lingxiao Zhao Jianwei Huang Qiang Gao Bing Shen Jing Liu Cheng Hu Wenjuan Zhao Genfu Chen Xiaowen Jia Li Yu Lin Zhao Shaolong He Fengfeng Zhang Shenjin Zhang Feng Yang Zhimin Wang Qinjun Peng Zuyan Xu Chuangtian Chen Xingjiang Zhou | 2017 | Science Bulletin2017,62,13: | 4 |
| 12 | Identification of HSC/MPP expansion units in fetal liver by single-cell spatiotemporal transcriptomics显示文摘Limited knowledge of cellular and molecular mechanisms underlying hematopoietic stem cell and multipotent progenitor(HSC/MPP)expansion within their native niche has impeded the application of stem cell-based therapies for hematological malignancies.Here,we constructed a spatiotemporal transcriptome map of mouse fetal liver(FL)as a platform for hypothesis generation and subsequent experimental validation of novel regulatory mechanisms.Single-cell transcriptomics revealed three transcriptionally heterogeneous HSC/MPP subsets,among which a CD93-enriched subset exhibited enhanced stem cell properties.Moreover,by employing integrative analysis of single-cell and spatial transcriptomics,we identified novel HSC/MPP‘pocket-like’units(HSC PLUS),composed of niche cells(hepatoblasts,stromal cells,endothelial cells,and macrophages)and enriched with growth factors.Unexpectedly,macrophages showed an 11-fold enrichment in the HSC PLUS.Functionally,macrophage-HSC/MPP co-culture assay and candidate molecule testing,respectively,validated the supportive role of macrophages and growth factors(MDK,PTN,and IGFBP5)in HSC/MPP expansion.Finally,cross-species analysis and functional validation showed conserved cell-cell interactions and expansion mechanisms but divergent transcriptome signatures between mouse and human FL HSCs/MPPs.Taken together,these results provide an essential resource for understanding HSC/MPP development in FL,and novel insight into functional HSC/MPP expansion ex vivo. | Suwei Gao Qiang Shi Yifan Zhang Guixian Liang Zhixin Kang Baofeng Huang Dongyuan Ma Lu Wang Jianwei Jiao Xiangdong Fang Cheng-Ran Xu Longqi Liu Xun Xu Berthold Gottgens Cheng Li Feng Liu | 2022 | Cell Research2022,32,1: | 4 |
| 13 | Ice-wedge Pseudomorphs Showing Climatic Change Since the Late Pleistocene in the Source Area of the Yellow River, Northeast Tibet显示文摘The source area of the Yellow River is located in the northeastern Tibetan Plateau, and is a high-elevation region with the annual mean temperature of-3.9℃. The ice-wedge pseudomorphs discovered in this region are recognized as two types.One was found in sandy gravel beds of the second terrace of the Yellow River. This ice-wedge pseudomorph is characterized by higher ratio of breadth/depth, and are 1~1.4 m wide and about 1 m deep. The bottom border of the ice-wedge pseudomorph is round arc in section. Another discovered in the pedestal of the second terrace has lower ratio of width/depth, and is 0.3~1.0 m wide and 1~2 m deep. Its bottom border is sharp. Based on the TL dating, the former was formed at the middle Holocene (5.69±0.43 ka BP and 5.43±0.41 ka BP),that is, the Megathermal, and the latter was formed at the late Last Glacial Maximum (13.49± 1.43 ka BP).Additionally, the thawing-freezing folders discovered in the late Late Pleistocene proluvium are 39.83±3.84 ka BP in age. The study on the ice-wedge pseudomorphs showed that the air temperature was lowered by up to 6~7 ℃ in the source area of the Yellow River when the ice-wedge pseudomorphs and thawing-freezing folds developed. | CHENG Jie ZHANG Xujiao TIAN Mingzhong YU Wenyang YU Jiangkuan TANG Dexiang YUE Jianwei | 2005 | Journal of Mountain Science2005,2,3: | 3 |
| 14 | Trends in Stroke Mortality Rate--China,2004-2019显示文摘Introduction:Stroke has been the leading cause of death in China for decades.This study described the trends in stroke mortality in China from 2004 to 2019.Methods:Data was obtained from the National Disease Surveillance Point(DSP)system.A descriptive analysis was conducted.The adjusted mortality rate(AMR)and age-standardized mortality rate(ASMR)of stroke were calculated.Results:From 2004 to 2019,the ASMR substantially decreased,with a reduction of 39.8%,but the AMR stayed relatively stable.The mortality rate of stroke in rural areas was consistently higher than in urban areas.A geographical gradient in mortality of stroke was also apparent,with an increased rate in the western part of China and a decreased rate in the eastern part of China.In central China,the rate remained relatively stable.Conclusions:Although the ASMR of stroke continued to decline in China,the stagnant crude mortality rates suggested that China had not achieved sufficient decline to offset the demographic forces of population growth and ageing.More vigorous and effective prevention and treatment strategies are urgently needed to mitigate the disease burden of stroke in China,especially in areas with high stroke burden and limited resources. | Junxia Cheng Wei Wang Jianwei Xu Ling Yin Yunning Liu Jing Wu | 2022 | China CDC weekly2022,4,24: | 3 |
| 15 | T cells expressing CD5/CD7 bispecific chimeric antigen receptors with fully human heavy-chain-only domains mitigate tumor antigen escape显示文摘Bispecific chimeric antigen receptor T-cell(CAR-T)therapies have shown promising results in clinical trials for advanced B-cell malignancies.However,it is challenging to broaden the success of bispecific CAR-T therapies to treat refractory/relapse(r/r)T-cell leukemia/lymphoma because targeting multiple T-cell-expressing antigens leads to exacerbated CAR-T cell fratricide and potential safety concerns.Fully human heavy chain variable(FHVH)antibodies that specifically target CD5 or CD7 were screened and constructed to CD5/CD7 bispecific CARs.A truncated Epidermal growth factor receptor were integrated into CAR constructs to address safety concerns.To tackle the fratricidal issue of CAR-T cells targeting T-cell-pan marker(s),CRISPR/Cas9-based CD5 and CD7 genes knockout were performed before lentiviral transduction of bispecific CARs.Functional comparison between different bispecific CAR structures:tandem CARs and dual CAR were performed in vitro and in vivo to determine the optimal construct suitable for addressing T-cell malignancy antigen escape in clinical setting.Knockout of CD5 and CD7 prevents fratricide of CD5/CD7 bispecific CAR-T cells,and FHVH-derived CD5/CD7 bispecific CAR-T cells demonstrate potent antitumor activity in vitro and in vivo.The fratricide-resistant FHVH-derived CD5/CD7 bispecific CAR-T cells have potent antitumor activity against T-cell malignancies,and tandem CARs are more effective than dual CAR in preventing tumor escape in heterogeneous leukemic cells.The meaningful clinical efficacy and safety of tandem CD5/CD7 CAR-T cells deserve to be explored urgently. | Zhenyu Dai Wei Mu Ya Zhao Jiali Cheng Haolong Lin Kedong Ouyang Xiangyin Jia Jianwei Liu Qiaoe Wei Meng Wang Chaohong Liu Taochao Tan Jianfeng Zhou | 2022 | Signal Transduction and Targeted Therapy2022,7,4: | 3 |
| 16 | General synthesis of hollow mesoporous conducting polymers by dual-colloid interface co-assembly for high-energy-density micro-supercapacitors显示文摘Rational design and precise regulation over the morphology, structure, and pore size of functional conducting mesoporous polymers with enriched active sites and shorten electron–ion transport pathway are extremely important for developing high-performance micro-supercapacitors (MSCs), but still remain a great challenge. Herein, a general dual-colloid interface co-assembly strategy is proposed to fabricate hollow mesoporous polypyrrole nano-bowls (mPPy-nbs) for high-energy-density solid-state planar MSCs. By simply adjusting the size of block copolymer micelles, the diameter of polystyrene nanospheres and the amount of pyrrole monomer, mesopore size of the shell, void and shell thickness of mPPy-nbs can be simultaneously controlled. Importantly, this strategy can be further utilized to synthesize other hollow mesoporous polymers, including poly(tris(4-aminophenyl)amine), poly(1,3,5-triaminobenzene) and their copolymers, demonstrative of excellent universality. The structurally optimized mPPy-nb exhibits high specific surface area of 122 m^(2) g^(−1)and large capacitance of 225 F g^(−1) at 1 mV s^(−1). Furthermore, the MSCs assembled by mPPy-nbs deliver impressive volumetric capacitance of 90 F cm^(−3) and energy density of 2.0 mWh cm^(−3), superior to the most reported polymers-based MSCs. Also, the fabricated MSCs present excellent flexibility with almost no capacitance decay under varying bending states, and robust serial/parallel self-integration for boosting voltage and capacitance output. Therefore, this work will inspire the new design of mesoporous conducting polymer materials toward high-performance microscale supercapacitive devices. | Jing Cui Fei-Fei Xing Hao Luo Jie-Qiong Qin Yan Li Yonghui Zhong Facai Wei Jianwei Fu Chengbin Jing Jiangong Cheng Zhong-Shuai Wu Shaohua Liu | 2021 | Journal of Energy Chemistry2021,30,11: | 3 |
| 17 | Ag doped urchin-like α-MnO2 toward efficient and bifunctional electrocatalysts for Li-02 batteries显示文摘Rechargeable Li-O2 batteries (LOBs) have been receiving intensive attention because of their ultra-high theoretical energy densityclose to the gasoline. Herein, Ag modified urchin-like α-MnO2 (Ag-MnO2) material with hierarchical porous structure is obtained bya facile one-step hydrothermal method. Ag-MnO2 possesses thick nanowires and presents hierarchical porous structure of mesoporesand macropores. The unique structure can expose more active sites, and provide continuous pathways for O2 and discharge productsas well. The doping of Ag leads to the change of electronic distribution in α-MnO2 (i.e., more oxygen vacancies), which playimportant roles in improving their intrinsic catalytic activity and conductivity. As a result, LOBs with Ag-MnO2 catalysts exhibit loweroverpotential, higher discharge specific capacity and much better cycle stability compared to pure a-MnO2. LOBs with Ag-MnO2catalysts exhibit a superior discharge specific capacity of 13,131 mA·h·g^-1 at a current density of 200 mA·h·g^-1, a good cycle stabilityof 500 cycles at the capacity of 500 mA·h·g^-1. When current density is increased to 400 mA·h·g^-1, LOBs still retain a long lifespan of170 cycles at a limited capacity of 1,000 mA·h·g^-1. | Linna Dai Qing Sun Lina Chen Huanhuan Guo Xiangkun Nie Jun Cheng Jianguang Guo Jianwei Li Jun Lou Lijie Ci | 2020 | Nano Research2020,13,9: | 2 |
| 18 | An attack-immune trusted architecture for supervisory aircraft hardware显示文摘With the wide application of electronic hardware in aircraft such as air-to-ground communication,satellite communication,positioning system and so on,aircraft hardware is facing great secure pressure.Focusing on the secure problem of aircraft hardware,this paper proposes a supervisory control architecture based on secure System-on-a-Chip(So C)system.The proposed architecture is attack-immune and trustworthy,which can support trusted escrow application and Dynamic Integrity Measurement(DIM)without interference.This architecture is characterized by a Trusted Monitoring System(TMS)hardware isolated from the Main Processor System(MPS),a secure access channel from TMS to the running memory of the MPS,and the channel is unidirectional.Based on this architecture,the DIM program running on TMS is used to measure and call the Lightweight Measurement Agent(LMA)program running on MPS.By this method,the Operating System(OS)kernel,key software and data of the MPS can be dynamically measured without disturbance,which makes it difficult for adversaries to attack through software.Besides,this architecture has been fully verified on FPGA prototype system.Compared with the existing systems,our architecture achieves higher security and is more efficient on DIM,which can fully supervise the running of application and aircraft hardware OS. | Dongxu CHENG Chi ZHANG Jianwei LIU Dawei LI Zhenyu GUAN Wei ZHAO Mai XU | 2021 | Chinese Journal of Aeronautics2021,34,11: | 2 |
| 19 | Optimal Control of a Universal Rotating Magnetic Vector for Petal-shaped Capsule Robot in Curve Environment显示文摘Steering control of a capsule robot in curve environment by magnetic navigation is not yet solved completely.A petal-shaped capsule robot with less steering resistance based on multiple wedge effects is presented,and an optimization method with two processes for determining the orientation of a pre-applied universal magnetic spin vector is proposed.To realize quick and non-contact steering swimming,a fuzzy comprehensive evaluation method for optimizing the steering driving angle is presented based on two evaluation indexes including the average steering speed and the average steering trajectory deviation,achieving the initial optimal orientation of a universal magnetic spin vector.To further reduce robotic magnetic vibration,a main target method for optimizing its final orientation,which is used for fine adjustment,is employed under the constrains of the magnetic moments.Swimming experimental results in curve pipe verified the effectiveness of the optimization method,which can be effectively used to realize non-contact steering swimming of the petal-shaped robot and reduce its vibration. | ZHANG Yongshun BAI Jianwei CHI Minglu CHENG Cunxin WANG Dianlong | 2014 | Chinese Journal of Mechanical Engineering2014,27,5: | 2 |
| 20 | A bioinformatics method for predicting long noncoding RNAs associated with vascular disease显示文摘Long noncoding RNAs(lncRNAs)play important roles in human diseases including vascular disease.Given the large number of lncRNAs,however,whether the majority of them are associated with vascular disease remains unknown.For this purpose,here we present a genomic location based bioinformatics method to predict the lncRNAs associated with vascular disease.We applied the presented method to globally screen the human lncRNAs potentially involved in vascular disease.As a result,we predicted 3043 putative vascular disease associated lncRNAs.To test the accuracy of the method,we selected 10 lncRNAs predicted to be implicated in proliferation and migration of vascular smooth muscle cells(VSMCs)for further experimental validation.The results confirmed that eight of the 10 lncRNAs(80%)are validated.This result suggests that the presented method has a reliable prediction performance.Finally,the presented bioinformatics method and the predicted vascular disease associated lncRNAs together may provide helps for not only better understanding of the roles of lncRNAs in vascular disease but also the identification of novel molecules for the diagnosis and therapy of vascular disease. | LI JianWei GAO Cheng WANG YuChen MA Wei TU Jian WANG JunPei CHEN ZhenZhen KONG Wei CUI QingHua | 2014 | Science China(Life Sciences)2014,57,8: | 2 |