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| 1 | A prospective comparative study on neovascular glaucoma and non- neovascular refractory glaucoma following Ahmed glaucoma valve implantation显示文摘 | Li Zheng Zhou Minwen Wang Wei Huang Wenbin Chen Shida Li Xingyi Gao Xinbo Zhang Xiulan | 2014 | Chinese Medical Journal2014,,8: | 18 |
| 2 | Discovery of biclonal origin and a novel oncogene SLC12A5 in colon cancer by single-cell sequencing显示文摘单个房间的定序是为描出的一个强大的工具为个性化的癌症管理的同种细胞的关系和识别关键司机基因。这里,我们执行了结肠癌的一个盒子的单个房间的定序的分析。人口遗传分析在肿瘤房间人口识别了二独立克隆。主要肿瘤克隆作为早 oncogenic 事件怀有 APC 和 TP53 变化,而次要的克隆包含了优势的 CDC27 和 PABPC1 变化。在这二克隆的次要的克隆支持的 APC 和 TP53 变化的缺席从二细胞的起源被导出。体的变化等位基因频率系列的检查另外 21 个整个织物的定序 exome 的盒子在结肠癌揭示了同种细胞的起源的异质。下次,我们识别了在单个房间的水平显示出变化的高频率,但是在人口水平展出了低流行的变异的基因 SLC12A5。变异的 SLC12A5 的功能的描述在结肠癌揭示了它的潜在的 oncogenic 效果。我们的学习在单个房间的水平支持提供第一条 exome 宽的证据那结肠癌能具有 biclonal 起源,并且建议在一个队的低流行的变化可以也在单个水平起重要 protumorigenic 作用。 | Chang Yu Jun Yu Xlaotlan Yao Wllham KK Wu Youyong Lu Senwel Tang Xiangchun Li Li Bao Xiaoxing Li Yong Hou Renhua Wu Min Jian Ruoyan Chen Fan Zhang Lixia Xu Fan Fan Jun He Qiaoyi Liang Hongyi Wang Xueda Hu Minghui He Xiang Zhang Hancheng Zheng Qibin Li Hanjie Wu Yan Chen Xu Yang Shida Zhu Xun Xu Huanming Yang Jian Wang Xiuqing Zhang Joseph JY Sung Yingrui Li Jun Wang | 2014 | Cell Research2014,,6: | 16 |
| 3 | Hierarchical structures in climate and atmospheric turbulence显示文摘The climatic time series encompass many time scales, forming multi-scale climatic variations and hierarchies. The periods and magnitudes of cooling or warming, especially for extreme climatic events, vary with the time scales. On the other hand, high-frequency atmospheric turbulent motions, which are certainly related to the climatic changes, are also typical multi-scale phenomena. In this paper, certain properties of the fluctuations are examined that are invariant with the change of the time scales. Specifically, the existence of a statistical similarity law is demonstrated in climatic time series and in atmospheric turbulent motions. This is the hierarchical similarity law. Further analyses show that the hierarchical similarity law is a general property of multi-scale fluctuation systems. Therefore, the study on the hierarchical similarity law is important for understanding the inherent universal physical mechanism of complex systems in the atmospheric motions. | SHE Zhensu, FU Zuntao, CHEN Jiong, LIANG Shuang and LIU Shida(1. State Key Laboratory for Studies of Turbulence and Complex Systems, Department of Mechanics and Engineering Sciences, Peking University, Beijing 100871, China 2. School of Physics, Peking University, Beijing 100871, China 3. LAPC, Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing 100029, China) | 2002 | Progress in Natural Science:Materials International2002,12,10: | 3 |
| 4 | Optical Perfect Shuffle Interconnection Using Computer-Generated Blazed Grating Array显示文摘 | Ping Xu Xiang Zhou Xiaochun Zhang Yongkang Guo Lurong Guo Hong Tang Shida Wu Lixing Yang Ying Chen | 1995 | Optical Review1995,,5: | 1 |
| 5 | Active-layer evolution and (CH3NH3)3Bi2l9-based solar substrate efficiency improvement of cell on TiO2-deposited ITO显示文摘 | Xinqian Zhang Gang Wu Zhuowei Gu Bing Guo Wenqing Liu Shida Yang Tao Ye Chen Chen Weiwei Tu Hongzheng Chen | 2016 | Nano Research2016,9,10: | 1 |
| 6 | Dimeric ellagitan-nins,Laevigatins E,F and G,from Rosa laevigata显示文摘 | Yo Shida T Tanaka K Chen XM | 1989 | Phytochemistry1989,37,: | 1 |
| 7 | cAMP-PGC1α途径诱导的抗Warburg效应驱动胶质母细胞瘤细胞分化为星形胶质细胞显示文摘文章简介多形性胶质母细胞瘤(GBM)是人类最具侵袭性的肿瘤之一。虽然分化治疗已被提出作为治疗GBM的潜在方法,但诱导分化的机制仍然很不清楚。在此,课题组利用c AMP激活剂建立了GBM诱导分化模型,该模型特异性地指导GBM分化为星形胶质细胞。 | Fan Xing Yizhao Luan Jing Cai Sihan Wu Jialuo Mai Jiayu Gu Haipeng Zhang Kai Li Yuan Lin Xiao Xiao Jiankai Liang Yuan Li Wenli Chen Yaqian Tan Longxiang Sheng Bingzheng Lu Wanjun Lu Mingshi Gao Pengxin Qiu Xingwen Su Wei Yin Jun Hu Zhongping Chen Ke Sai Jing Wang Furong Chen Yinsheng Chen Shida Zhu Dongbing Liu Shiyuan Cheng 谢志 朱文博 颜光美 | 2018 | 科学新闻2018,0,4: | 1 |
| 8 | Dimericellagitannins,Laevigatins E,F and G,from Rosa laevigata显示文摘 | Yo Shida T Tanaka K Chen XM | 1989 | Phytochemistry1989,28,9: | 1 |
| 9 | Coil-to-Stretch Transition of Binder Chains Enabled by“Nano-Combs”to Facilitate Highly Stable SiO_(x) Anode显示文摘The commercialized binder carboxymethyl cellulose sodium(CMC-Na)is considered unsuitable for micro-sized SiO_(x) anode as it cannot endure the large volume change to retain the conductive network during repeated charge/discharge cycles.Herein,a small amount of silicon nanoparticles(SiNPs)is added during slurry preparation process as“nano-combs”to unfold the convoluted CMC-Na polymer chains so that they undergo a coilto-stretch transition by interaction between polar groups(e.g.,-OH,-COONa)of polymer and SiNPs’large surface.Through maximizing the utilization of binders,a uniform conductive network is constructed with increased interfacial contact with micro-sized SiO_(x).As a result,the SiO_(x) electrode with optimized(10 wt%)SiNPs addition shows significantly improved initial capacity and cycling performance.Through revisiting CMCNa,a currently deemed unqualified binder in SiO_(x) anode,this work gives a brand-new perspective on the failing mechanism of Si-based anode materials and an improving strategy for electrode preparation. | Shida Xue Yanda Fu Zhibo Song Shiming Chen Yuchen Ji Yan Zhao Huizhi Wang Guoyu Qian Luyi Yang Feng Pan | 2022 | Energy & Environmental Materials2022,5,4: | 0 |
| 10 | Regulation of RNA methylation and immune infiltration patterns by m5C regulators in head and neck squamous cell carcinoma显示文摘5-Methylcytosine(m5C)methylation contributes to the development and progression of various malignant tumors.This study aimed to explore the potential role of m5C methylation regulators(m5CMRs)in head and neck squamous cell carcinoma(HNSCC).Methods:The transcription data of HNSCC samples were obtained from The Cancer Genome Atlas(TCGA)and the Gene Expression Omnibus(GEO)databases.Subsequently,the m5C patterns in HNSCC were evaluated based on 14 m5CMRs.Then,the m5Cscore was developed to quantify m5C patterns by using principal component analysis(PCA)algorithms.Two single-cell RNA sequencing datasets and various methods were employed to assess the prognostic value and sensitivity to immunotherapy.Finally,key prognostic m5CMRs were identified using univariate COX regression analysis,and their clinical significance was validated based on the Human Protein Atlas(HPA)database and by using immunohistochemistry.Results:Two distinct m5C clusters were identified.m5C cluster A is characterized by an immune-activated microenvironment and is associated with a favorable prognosis.Notable differences were observed in prognosis,immune infiltration,and immunotherapy response between the high-and low-m5Cscore groups.Patients in the high-m5Cscore group exhibited high TMB,which is correlated with poor prognosis.The m5Cscore of epithelial cells in HNSCC was higher than that in other cells.Key prognostic m5CMRs,including NSUN2,DNMT3B,ALKBH1,and Y-Box Binding Protein 1(YBX1),were associated with poor prognosis.Conclusion:Our research indicates that in head and neck squamous cell carcinoma,the m5C modification profoundly affects the TME’s diversity and complexity,influencing prognosis and the success of immunotherapy.Targeting m5C regulatory elements may be a new method for enhancing the efficacy of immunotherapy in HNSCC. | SHIDA HOU TIANJUN LAN YAOCHENG YANG PEISHENG LIANG XIN LIU JUNJIE WANG ZHIFENG CHEN RONGSHENG ZENG ZIJING HUANG | 2023 | BIOCELL2023,47,12: | 0 |
| 11 | Polymeric Wetting Matrix for a Stable Interface between Solid-state Electrolytes and Li Metal Anode显示文摘Succinonitrile(SN)based solid-state electrolytes(SSEs)have potential applications in lithium(Li)batteries due to their ease of preparation and high ionic conductivity at room temperature.Here,a novel SSE consisting of poly(vinylidene fluoride-hexafluoropropy-lene)(PVDF-HFP),poly(methyl methacrylate)(PMMA)and Li_(1.3)Al_(0.3)Ti_(1.7)(PO_(4))_(3) with SN is fabricated,where PMMA is added to serve as a polymer matrix for better wettability of SN.Due to the addition of PMMA,improved room-temperature ionic conductivity of the SSE is resulted.More importantly,better interfacial contact as well as more stable solid-state electrolyte(SEI)layer between SSE and Li anode can be also obtained.As a result,homogeneous and dendrite-free Li plating can be achieved for over 1000 h in Li symmetric cells.When coupled with LiNi_(0.5)Mn_(0.3)Co_(0.2)O_(2) cathode and Li anode,the proposed SSE delivers excellent cycling stability and rate capability in full-cells.By implementing SSEs with a polymeric wetting agent,this work provides fresh perspectives on stabilizing the interface between SSEs and Li metal anodes. | Haoran Song Shida Xue Shiming Chen Zijian Wang Yongli Song Jiawen Li Zhibo Song Luyi Yang Feng Pan | 2022 | Chinese Journal of Structural Chemistry2022,41,5: | 0 |