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| 1 | Guidelines on multidisciplinary approaches for the prevention and management of diabetic foot disease(2020 edition)显示文摘In recent years,as living standards have continued to improve,the number of diabetes patients in China,along with the incidence of complications associated with the disease,has been increasing.Among these complications,diabetic foot disease is one of the main causes of disability and death in diabetic patients.Due to the differences in economy,culture,religion and level of medical care available across different regions,preventive and treatment methods and curative results for diabetic foot vary greatly.In multidisciplinary models built around diabetic foot,the timely assessment and diagnosis of wounds and appropriate methods of prevention and treatment with internal and external surgery are key to clinical practice for this pathology.In 2019,under the leadership of the Jiangsu Medical Association and Chinese Diabetes Society,the writing group for the Guidelines on multidisciplinary approaches for the prevention and management of diabetic foot disease(2020 edition)was established with the participation of scholars from the specialist areas of endocrinology,burn injury,vascular surgery,orthopedics,foot and ankle surgery and cardiology.Drawing lessons from diabetic foot guidelines from other countries,this guide analyses clinical practices for diabetic foot,queries the theoretical basis and grades and gives recommendations based on the characteristics of the pathology in China.This paper begins with assessments and diagnoses of diabetic foot,then describes treatments for diabetic foot in detail,and ends with protections for high-risk feet and the prevention of ulcers.This manuscript covers the disciplines of internal medicine,surgical,nursing and rehabilitation and describes a total of 50 recommendations that we hope will provide procedures and protocols for clinicians dealing with diabetic foot. | Aiping Wang Guozhong Lv Xingbo Cheng Xianghua Ma Wei Wang Jianchao Gui JiHu Meng Lu Guoping Chu Jin’an Chen Hao Zhang Yiqiu Jiang Yuedong Chen Wengbo Yang Lin Jiang Houfa Geng Rendong Zheng Yihui Li Wei Feng Boey Johnson Wenjuan Wang Dalong Zhu Yin Hu | 2020 | Burns & Trauma2020，8，1： | 34 |
| 2 | 新疆地区维、汉民族冠状动脉粥样硬化性心脏病患者血脂分析(英文)显示文摘目的通过分析维吾尔族和汉族冠状动脉粥样硬化性心脏病与血脂的水平,探讨两民族冠状动脉粥样硬化性心脏病与血脂的关系以及不同民族间的差异。方法对487例冠状动脉粥样硬化性心脏病(维吾尔族245例,汉族242例)和167例正常人(维吾尔族75例,汉族92例)进行了血清总胆固醇(TC)、高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)、三酰甘油(TG)和空腹血糖(FG)的检测。组间年龄和性别均有可比性。结果维吾尔族冠状动脉粥样硬化性心脏病组TC,LDL-C,TG和FG水平较对照组升高(q=10.01,12.69,4.45,6.78;P<0.01),HDL-C较对照组降低(q=6.95,P<0.01)。汉族冠状动脉粥样硬化性心脏病组TC,LDL-C,TG和FG水平较对照组升高(q=10.06,11.89,6.35,5.96;P<0.01),HDL-C较对照组降低(P<0.01)。两民族冠状动脉粥样硬化性心脏病组间和对照组间差别无统计学意义(q=0.35~1.41,P>0.05)。结论血脂紊乱、血糖升高均为冠状动脉粥样硬化性心脏病的危险因素。 | 楚新梅 孟竹 何秉贤 戴文英 Chu Xinmei MENG Zhu He Bingxian Dai Wenying | 2003 | 中国临床康复2003，7，9： | 30 |
| 3 | Isolation and Identification of Cancer Stem-Like Cells from Murine Melanoma Cell Lines显示文摘In current study,cancer stem-like cells in the murine melanoma B16F10 cells were investigated.CD phenotypes of the B16F10 cells were analyzed by flow cytometry,and the specific CD phenotype cells from the B16F10 cells were isolated by MACS.Then we used colony formation assay in soft agar media,the cell growth assay in serum-free culture media as well as the tumorigenicity investigation of the specific CD phenotype cells in C57BL/6 mice, respectively,to identify cancer stem-like cells in the B16F10 cells.The results showed that the B16F10 cells could form spherical clones in serum-free culture media,and the rate of clonegenesis of CD133 + ,CD44 + and CD44 + CD133 + cells was higher than that of CD133 - ,CD44 - and CD44 + CD133 - cells in soft agar media,respectively. The tumorigenic potential of CD133 + ,CD44 + ,CD44 + CD133 + cells and CD44 + CD133 + CD24 + cells was stronger than that of CD133 - ,CD44 - ,CD44 + CD133 - cells and CD44 + CD133 + CD24 - cells in mice,respectively.In conclusion,the CD44 + CD133 + CD24 + cells have some biological properties of cancer stem-like cells or are highly similar to the characteristics of cancer stem cells(CSC).These results provide an important method for identifying cancer stem-like cells in B16F10 cells and for further cancer target therapy. | Jun Dou Meng Pan Ping Wen Yating Li Quan Tang Lili Chu Fengshu Zhao Chuilian Jiang Weihua Hu Kai Hu Ning Gu | 2007 | Cellular & Molecular Immunology2007，4，6： | 25 |
| 4 | A Strigolactone Biosynthesis Gene Contributed to the Green Revolution in Rice显示文摘Plant architecture is a complex agronomic trait and a major factor of crop yield,which is affected by several important hormones.Strigolactones(SLs)are identified as a new class hormoneinhibiting branching in many plant species and have been shown to be involved in various developmental processes.Genetical and chemical modulation of the SL pathway is recognized as a promising approach to modify plant architecture.However,whether and how the genes involved in the SL pathway could be utilized in breeding still remain elusive.Here,we demonstrate that a partial loss-of-function allele of the SL biosynthesis gene,HIGH TILLERING AND DWARF 1/DWARF17(HTD1/D17),which encodes CAROTENOID CLEAVAGE DIOXYGENASE 7(CCD7),increases tiller number and improves grain yield in rice.We found that the HTD1 gene had been widely utilized and co-selected with Semidwarf 1(SD1),both contributing to the improvement of plant architecture in modern rice varieties since the Green Revolution in the 1960s.Understanding how phytohormone pathway genes regulate plant architecture and how they have been utilized and selected in breeding will lay the foundation for developing the rational approaches toward improving crop yield. | Yuexing Wang Lianguang Shang Hong Yu Longjun Zeng Jiang Hu Shen Ni Yuchun Rao Sanfeng Li Jinfang Chu Xiangbing Meng Lei Wang Ping Hu Jijun Yan Shujing Kang Minghao Qu Hai Lin Tao Wang Quan Wang Xingming Hu Hongqi Chen Bing Wang Zhenyu Gao Longbiao Guo Dali Zeng Xudong Zhu Guosheng Xiong Jiayang Li Qian Qian | 2020 | Molecular Plant2020，13，6： | 23 |
| 5 | Immunogenicity noninferiority study of 2 doses and 3 doses of an Escherichia coli-produced HPV bivalent vaccine in girls vs.3 doses in young women显示文摘A new HPV-16/18 bivalent vaccine expressed by the Escherichia coli has been proven to be efficacious in adult women.A randomized,immunogenicity noninferiority study of this candidate vaccine was conducted in December 2015 in China.Girls aged 9–14 years were randomized to receive 2 doses at months 0 and 6(n=301)or 3 doses at months 0,1 and 6(n=304).Girls aged 15–17 years(n=149)and women aged 18–26 years(n=225)received 3 doses.The objectives included noninferiority analysis of the IgG geometric mean concentration(GMC)ratio(95%CI,lower bound>0.5)to HPV-16 and HPV-18 at month 7 in girls compared with women.In the per-protocol set,the GMC ratio of IgG was noninferior for girls aged 9–17 years receiving 3 doses compared with women(1.76(95%CI,1.56,1.99)for HPV-16 and 1.93(95%CI,1.69,2.21)for HPV-18)and noninferior for girls aged 9–14 years receiving 2 doses compared with women(1.45(95%CI,1.25,1.62)for HPV-16 and 1.17(95%CI,1.02,1.33)for HPV-18).Noninferiority was also demonstrated for neutralizing antibodies.The immunogenicity of the HPV vaccine in girls receiving 3 or 2 doses was noninferior compared with that in young adult women. | Yue-Mei Hu Meng Guo Chang-Gui Li Kai Chu Wen-Gang He Jing Zhang Jian-Xiang Gu Juan Li Hui Zhao Xiang-Hong Wu Bi-Zhen Lin Zhi-Jie Lin Xing-Mei Yao Ya-Fei Li Fei-Xue Wei Yue Huang Ying-Ying Su Feng-Cai Zhu Shou-Jie Huang Hui-Rong Pan Ting Wu Jun Zhang Ning-Shao Xia | 2020 | Science China(Life Sciences)2020，63，4： | 19 |
| 6 | MESHING THEORY AND DESIGN METHOD OF NEW SILENT CHAIN AND SPROCKET显示文摘基于新沉默的链的协调理论的学习并且链轮齿,并且滚动切链轮齿和壁炉内部的一锅架,在新沉默的链之中统治尺寸的和谐关系,链轮齿和壁炉内部的一锅架的理论造,协调条件是 expatiated ,和解决的表示,它能指示设计和计算,被引出。协调设计方法是可行的 Thetests 表演。 | MENG Fanzhong FENG Zengming CHU Yaxu | 2006 | Chinese Journal of Mechanical Engineering2006，19，3： | 16 |
| 7 | Global Pharmacopoeia Genome Database is an integrated and mineable genomic database for traditional medicines derived from eight international pharmacopoeias显示文摘Genomic data have demonstrated considerable traction in accelerating contemporary studies in traditional medicine. However,the lack of a uniform format and dispersed storage limits the full potential of herb genomic data. In this study, we developed a Global Pharmacopoeia Genome Database(GPGD). The database contains 34,346 records for 903 herb species from eight global pharmacopoeias(Brazilian, Egyptian, European, Indian, Japanese, Korean, the Pharmacopoeia of the People’s Republic of China, and U.S. Pharmacopoeia’s Herbal Medicines Compendium). In particular, the GPGD contains 21,872 DNA barcodes from 867 species, 2,203 organelle genomes from 674 species, 55 whole genomes from 49 species, 534 genomic sequencing datasets from 366 species, and 9,682 transcriptome datasets from 350 species. Among the organelle genomes, 534 genomes from 366 species were newly generated in this study. Whole genomes, organelle genomes, genomic fragments, transcriptomes, and DNA barcodes were uniformly formatted and arranged by species. The GPGD is publicly accessible at http://gffzzf938e9d610ce4c4ahn6kqo6xopb5o6906.ffgz.tsg.suse.edu.cn and serves as an essential resource for species identification, decomposition of biosynthetic pathways, and molecular-assisted breeding analysis. Thus, the database is an invaluable resource for future studies on herbal medicine safety, drug discovery, and the protection and rational use of herbal resources. | Baosheng Liao Haoyu Hu Shuiming Xiao Guanru Zhou Wei Sun Yang Chu Xiangxiao Meng Jianhe Wei Han Zhang Jiang Xu Shilin Chen | 2022 | Science China(Life Sciences)2022，65，4： | 11 |
| 8 | ζ-Carotene Isomerase Suppresses Tillering in Rice through the Coordinated Biosynthesis of Strigolactone and Abscisic Acid显示文摘Rice tillering is an important agronomic trait affecting grain yield.Here,we identified a high-tillering mutant tillering20(t20),which could be restored to the wild type by treatment with the strigolactone(SL)analog rac-GR24.T20 encodes a chloroplast ζ-carotene isomerase(Z-ISO),which is involved in the biosynthesis of ca-rotenoids and their metabolites,SL and abscisic acid(ABA).The t20 mutant has reduced SL and ABA,raising the question of how SL and ABA biosynthesis is coordinated,and whether they have overlapping functions in tillering.We discovered that rac-GR24 stimulated T20 expression and enhanced all-trans-p-carotene biosynthesis.Importantly,rac-GR24 also stimulated expression of Oryza sativa 9-CIS-EPOXY-CAROTENOID DIOXYGENASE 1(OsNCED1)through induction of Oryza sativa HOMEOBOX12(0sHOX12),promoting ABA biosynthesis in shoot base.On the other hand,ABA treatment significantly repressed SL biosynthesis and the ABA biosynthetic mutants displayed elevated SL biosynthesis.ABA treatment reduced the number of basal tillers in both t20 and wild-type plants.Furthermore,while ABA-deficient mu-tants aba1 and aba2 had the same number of basal tillers as wild type,they had more unproductive upper tillers at maturity.This work demonstrates complex interactions in the biosynthesis of carotenoid,SLs and ABA,and reveals a role for ABA in the regulation of rice tillering. | Xue Liu Qingliang Hu Jijun Yan Kai Sun Yan Liang Meiru Jia Xiangbing Meng Shuang Fang Yiqin Wang Yanhui Jing Guifu Liu Dianxing Wu Chengcai Chu Steven M.Smith Jinfang Chu Yonghong Wang Jiayang Li Bing Wang | 2020 | Molecular Plant2020，13，12： | 11 |
| 9 | Immunogenicity and safety of a severe acute respiratory syndrome coronavirus 2 inactivated vaccine in healthy adults: randomized, double-blind, and placebo-controlled phase 1 and phase 2 clinical trials显示文摘Background:The significant morbidity and mortality resulted from the infection of a severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)call for urgent development of effective and safe vaccines.We report the immunogenicity and safety of an inactivated SARS-CoV-2 vaccine,KCONVAC,in healthy adults.Methods:Phase 1 and phase 2 randomized,double-blind,and placebo-controlled trials of KCONVAC were conducted in healthy Chinese adults aged 18 to 59 years.The participants in the phase 1 trial were randomized to receive two doses,one each on Days 0 and 14,of either KCONVAC(5 or 10 mg/dose)or placebo.The participants in the phase 2 trial were randomized to receive either KCONVAC(at 5 or 10 mg/dose)or placebo on Days 0 and 14(0/14 regimen)or Days 0 and 28(0/28 regimen).In the phase 1 trial,the primary safety endpoint was the proportion of participants experiencing adverse reactions/events within 28 days following the administration of each dose.In the phase 2 trial,the primary immunogenicity endpoints were neutralization antibody seroconversion and titer and anti-receptor-binding domain immunoglobulin G seroconversion at 28 days after the second dose.Results:Inthe phase1 trial,60 participantswere enrolled andreceived at least one dose of 5-mgvaccine(n=24),10-mgvaccine(n=24),or placebo(n=12).In the phase 2 trial,500 participantswere enrolled and received at least one dose of 5-mg vaccine(n=100 for 0/14 or 0/28 regimens),10-mg vaccine(n=100 for each regimen),or placebo(n=50 for each regimen).In the phase 1 trial,13(54%),11(46%),and seven(7/12)participants reported at least one adverse event(AE)after receiving 5-,10-mg vaccine,or placebo,respectively.In the phase 2 trial,16(16%),19(19%),and nine(18%)0/14-regimen participants reported at least oneAEafter receiving 5-,10-mg vaccine,or placebo,respectively.Similar AE incidences were observed in the three 0/28-regimen treatment groups.No AEs with an intensity of grade 3+were reported,expect for one vaccine-unrelated seriousAE(foot fracture)reported in the phase 1 trial.KCONVACinduced significant antibody responses;0/28 regimen showed a higher immune responses than that did 0/14 regimen after receiving two vaccine doses.Conclusions:Both doses of KCONVAC are well tolerated and able to induce robust immune responses in healthy adults.These results support testing 5-mg vaccine in the 0/28 regimen in an upcoming phase 3 efficacy trial.Trial Registration:http://gffzz62a03ee25e6f4a77hn6kqo6xopb5o6906.ffgz.tsg.suse.edu.cn/index.aspx(No.ChiCTR2000038804,http://gffzz62a03ee25e6f4a77hn6kqo6xopb5o6906.ffgz.tsg.suse.edu.cn/showproj.aspx?proj=62350;No.ChiCTR2000039462,http://gffzz62a03ee25e6f4a77hn6kqo6xopb5o6906.ffgz.tsg.suse.edu.cn/showproj.aspx?proj=63353). | Hong-Xing Pan Jian-Kai Liu Bao-Ying Huang Gui-Fan Li Xian-Yun Chang Ya-Fei Liu Wen-Ling Wang Kai Chu Jia-Lei Hu Jing-Xin Li Dan-Dan Zhu Jing-Liang Wu Xiao-Yu Xu Li Zhang Meng Wang Wen-Jie Tan Wei-Jin Huang Feng-Cai Zhu | 2021 | Chinese Medical Journal2021，，11： | 11 |
| 10 | Oncogenic AURKA-enhanced N6-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells显示文摘RNase III DROSHA is upregulated in multiple cancers and contributes to tumor progression by hitherto unclear mechanisms.Here,we demonstrate that DROSHA interacts withβ-Catenin to transactivate STC1 in an RNA cleavage-independent manner,contributing to breast cancer stem-like cell(BCSC)properties.DROSHA mRNA stability is enhanced by N6-methyladenosine(m^(6)A)modification which is activated by AURKA in BCSCs.AURKA stabilizes METTL14 by inhibiting its ubiquitylation and degradation to promote DROSHA mRNA methylation.Moreover,binding of AURKA to DROSHA transcript further strengthens the binding of the m^(6)A reader IGF2BP2 to stabilize m^(6)A-modified DROSHA.In addition,wild-type DROSHA,but not an m^(6)A methylation-deficient mutant,enhances BCSC stemness maintenance,while inhibition of DROSHA m^(6)A modification attenuates BCSC traits.Our study unveils the AURKA-induced oncogenic m^(6)A modification as a key regulator of DROSHA in breast cancer and identifies a novel DROSHA transcriptional function in promoting the BCSC phenotype. | Fei Peng Jie Xu Bai Cui Qilan Liang Sai Zeng Bin He Hong Zou Manman Li Huan Zhao Yuting Meng Jin Chen Bing Liu Shasha Lv Peng Chu Fan An Zifeng Wang Junxiu Huang Yajing Zhan Yuwei Liao Jinxin Lu Lingzhi Xu Jin Zhang Zhaolin Su Zhiguang Li Fangjun Wang Eric W-FLam Quentin Liu | 2021 | Cell Research2021，31，3： | 9 |
| 11 | AI-Based Modeling and Data-Driven Evaluation for Smart Manufacturing Processes显示文摘Smart manufacturing refers to optimization techniques that are implemented in production operations by utilizing advanced analytics approaches. With the widespread increase in deploying industrial internet of things(IIOT) sensors in manufacturing processes, there is a progressive need for optimal and effective approaches to data management.Embracing machine learning and artificial intelligence to take advantage of manufacturing data can lead to efficient and intelligent automation. In this paper, we conduct a comprehensive analysis based on evolutionary computing and neural network algorithms toward making semiconductor manufacturing smart.We propose a dynamic algorithm for gaining useful insights about semiconductor manufacturing processes and to address various challenges. We elaborate on the utilization of a genetic algorithm and neural network to propose an intelligent feature selection algorithm. Our objective is to provide an advanced solution for controlling manufacturing processes and to gain perspective on various dimensions that enable manufacturers to access effective predictive technologies. | Mohammadhossein Ghahramani Yan Qiao Meng Chu Zhou Adrian O’Hagan James Sweeney | 2020 | IEEE/CAA Journal of Automatica Sinica2020，7，4： | 9 |
| 12 | Repeatability and Reproducibility of Quantitative Assessment of the Retinal Microvasculature Using Optical Coherence Tomography Angiography Based on Optical Microangiography显示文摘Objective The aim of this study was to determine the repeatability and reproducibility of optical coherence tomography angiography(OCTA) based on optical microangiography(OMAG) measurements of macular vessels in normal eyes. Methods In this prospective cohort study, 40 eyes of 40 healthy volunteers underwent repeated OCTA(Cirrus HD-OCT 5000 angiography system, Carl Zeiss Meditec, Inc.) scans on two separate visit days. On each visit day, the eyes were scanned three times. The following parameters were used to quantitatively describe the OCTA images of the superficial vascular network: vessel area density(VAD), vessel skeleton density(VSD), vessel diameter index(VDI), vessel perimeter index(VPI), vessel complexity index(VCI), flux, and foveal avascular zone(FAZ). Coefficient of variation(CV) and intraclass correlation coefficient(ICC) were calculated for evaluating intravisit and intervisit repeatability, as well as interobserver reproducibility. Results The measurements showed high repeatability [CVs ≤ 4.2%(intravisit) and ≤ 4.6%(intervisit)] and interobserver reproducibility(ICCs ≥ 0.923) for all parameters. Conclusion This study demonstrated good repeatability and reproducibility of OCTA based on OMAG for the measurement of superficial vessel parameters in normal eyes. | ZHAO Qi YANG Wen Li WANG Xiao Na Ruikang K Wang YOU Qi Sheng CHU Zhong Di XIN Chen ZHANG Meng Yu LI Dong Jun WANG Zi Yang CHEN Wei LI Yi Feng CUI Rui SHEN Lin WEI Wen Bin | 2018 | Biomedical and Environmental Sciences2018，31，6： | 8 |
| 13 | A novel two-layered optical satellite network of LEO/MEO with zero phase factor显示文摘Optical satellite communication has advantages over the RF satellite communication in capacity, speed, secrecy and anti-interference.Space information superhighway composed of GEO/MEO/LEO satellites which are linked by optical inter-satellite links(OISL) would play important roles in communication, navigation, martial recon, remote sensing and deep space exploration.A novel LEO/MEO two-layered optical satellite network with global coverage is designed with the street-of-coverage technique.The layer of LEO satellites is the walker-delta constellation with zero phase factor and has the quasi-stable logical structure of Mesh.Equatorial and polar orbit satellites constitute the layer of MEO satellite, which can cover LEO layer effectively.Rising satellites of the system can provide 99.9% of coverage for the whole globe and 100% for China averagely.The network can provide a minimum elevation angle at 21 ? with single-satellite visibility for China, and at 16 ? with the dual-satellite visibility.Simulation results of the inter-satellite links show LEO constellation of zero phase factor outperforms non-zero phase factor constellations in azimuth angle, elevation angle and distance, which is very fit for the OISL.Simulation results of the communication performance indicate a little difference between short wave band and long wave band at low communication speed(several Gbit/s);however, the wave band at 1550 nm is a better choice at high communication speed(100 Gbit/s). | LI YongJun , WU JiLi, ZHAO ShangHong, MENG Wen, MA LiHua, SHI Lei, CHU XingChun, HOU Rui & LI Tian Telecommunication Engineering Institute, Air Force Engineering University, Xi’an 710077, China | 2010 | Science China(Information Sciences)2010，53，6： | 8 |
| 14 | Optimal incision sites to reduce corneal aberration variations after small incision phacoemulsification cataract surgery显示文摘AIM: To analyze the effect of steep meridian small incision phacoemulsification cataract surgery on anterior,posterior and total corneal wavefront aberration.· METHODS: Steep meridian small incision phacoemulsification cataract surgery was performed in age-related cataract patients which were divided into three groups according to the incision site: 12 o'clock, 9o'clock and between 9 and 12 o'clock(BENT) incision groups. The preoperative and 3-month postoperative root mean square(RMS) values of anterior, posterior and total corneal wavefront aberration including coma,spherical aberration, and total higher-order aberrations(HOAs), were measured by Pentacam scheimpflug imaging. The mean preoperative and postoperative corneal wavefront aberrations were documented.·RESULTS: Total corneal aberration and total lower-order aberrations decreased significantly in three groups after operation. RMS value of total HOAs decreased significantly postoperatively in the 12 o'clock incision group(P <0.001). Corneal spherical aberration was statistically significantly lower after steep meridian small incision phacoemulsification cataract surgery in BENT incision group(P <0.05) and Pearson correlation analysisindicated that spherical aberration changes had no significant relationship with total astigmatism changes in all three corneal incision location.·CONCLUSION: Corneal incision of phacoemulsification cataract surgery can affect corneal wavefront aberration.The 12 o'clock corneal incision eliminated more HOAs and the spherical aberrations decreased in BENT incision group obviously when we selected steep meridian small incision. Cataract lens replacement using wavefront-corrected intraocular lens combined with optimized corneal incision site would improve ocular aberration results. | Ling Chu Jiang-Yue Zhao Jin-Song Zhang Jie Meng Ming-Wu Wang Ya-Jing Yang Jia-Ming Yu | 2016 | International Journal of Ophthalmology(English edition)2016，9，4： | 8 |
| 15 | Construction of a macromolecular structural model of Chinese lignite and analysis of its low-temperature oxidation behavior显示文摘The aim of this paper is to analyze the change in the active structure of lignite during the process of lowtemperature oxidation by constructing a molecular structure model for lignite. Using quantum computation combined with experimental results of proximate analysis, ultimate analysis, Fourier transform infrared spectroscopy(FTIR) and X-ray photoelectron spectroscopy(XPS), a structural model for the large molecular structure was constructed. By analyzing the bond lengths in the model molecule, the evolution law for the active structure of lignite was predicted for the process of low-temperature oxidation. In low-temperature oxidation,alkanes and hydroxyls are the primary active structures observed in lignite, though ether may also react. These active functional groups react with oxygen to release heat, thereby speeding up the reaction between coal and oxygen. Finally, the content of various functional groups in the process of lignite low-temperature oxidation was analyzed by infrared analysis, and the accuracy of the model was verified. | Xianliang Meng Mingqiang Gao Ruizhi Chu Zhenyong Miao Guoguang Wu Lei Bai Peng Liu Yuanfang Yan Pengcheng Zhang | 2017 | Chinese Journal of Chemical Engineering2017，25，9： | 8 |
| 16 | Carbonaceous and nitrogenous disinfection by-product formation in the surface and ground water treatment plants using Yellow River as water source显示文摘This work investigated the formation of carbonaceous and nitrogenous disinfection by-products (C-DBPs, N-DBPs) upon chlorination of water samples collected from a surface water and a ground water treatment plant (SWTP and GWTP) where the conventional treatment processes, i.e., coagulation, sedimentation, and filtration were employed. Twenty DBPs, including four trihalomethanes, nine haloacetic acids, seven N-DBPs (dichloroacetamide, trichloroacetamide, dichloroacetonitrile, trichloroacetonitrile, bromochloroace-tonitrile, dibromoacetonitrile and trichloronitromethane), and eight volatile chlorinated compounds (dichloromethane (DCM), 1,2-dichloroethane, tetrachloroethylene, chlorobenzene, 1,2-dichlorobenzene, 1,4-dichlorobenzene, 1,2,3-trichlorobenzene and 1,2,4-trichlorobenzene) were detected in the two WTPs. The concentrations of these contaminants were all below their corresponding maximum contamination levels (MCLs) regulated by the Standards for Drinking Water Quality of China (GB5749-2006) except for DCM (17.1 μg/L detected vs. 20 μg/L MCL). The SWTP had much higher concentrations of DBPs detected in the treated water as well as the DBP formation potentials tested in the filtered water than the GWTP, probably because more precursors (e.g., dissolved organic carbon, dissolved organic nitrogen) were present in the water source of the SWTP. | Yukun Hou Wenhai Chu Meng Ma | 2012 | Journal of Environmental Sciences2012，24，7： | 7 |
| 17 | Nonlinear Bayesian Estimation: From Kalman Filtering to a Broader Horizon显示文摘This article presents an up-to-date tutorial review of nonlinear Bayesian estimation. State estimation for nonlinear systems has been a challenge encountered in a wide range of engineering fields, attracting decades of research effort. To date,one of the most promising and popular approaches is to view and address the problem from a Bayesian probabilistic perspective,which enables estimation of the unknown state variables by tracking their probabilistic distribution or statistics(e.g., mean and covariance) conditioned on a system's measurement data.This article offers a systematic introduction to the Bayesian state estimation framework and reviews various Kalman filtering(KF)techniques, progressively from the standard KF for linear systems to extended KF, unscented KF and ensemble KF for nonlinear systems. It also overviews other prominent or emerging Bayesian estimation methods including Gaussian filtering, Gaussian-sum filtering, particle filtering and moving horizon estimation and extends the discussion of state estimation to more complicated problems such as simultaneous state and parameter/input estimation. | Huazhen Fang Ning Tian Yebin Wang Meng Chu Zhou Mulugeta A. Haile | 2018 | IEEE/CAA Journal of Automatica Sinica2018，5，2： | 7 |
| 18 | A long noncoding RNA involved in rice reproductive development by negatively regulating osa-miR160显示文摘Long noncoding RNAs(lnc RNAs) participate in the regulation of multiple biological processes via diverse manners,one of which is functioning as endogenous target mimics(e TMs) to modulate micro RNAs(mi RNAs) by competing for their targets.Previously,we have predicted one lnc RNA(osa-e TM160) as an endogenous repressor of osa-mi R160 and validated the target mimicry ability of osa-e TM160 for ath-mi R160 in Arabidopsis thaliana,yet the functions of osa-e TM160 in rice remain obscure.Here,we demonstrated that osa-e TM160 attenuated the repression of osa-mi R160 on osa-ARF18 m RNAs during early anther developmental stages through the target mimicry manner,therefore to regulate rice seed setting and seed size.These findings revealed the roles of osa-e TM160 in rice,and indicated that lnc RNAs with e TM functions may serve as temporal regulators to modulate the effects of mi RNAs at specific developmental stages. | Meng Wang Hua-Jun Wu Jun Fang Chengcai Chu Xiu-Jie Wang | 2017 | Science Bulletin2017，62，7： | 6 |
| 19 | Multiple linear equation of pore structure and coal–oxygen diffusion on low temperature oxidation process of lignite显示文摘This work aimed at studying the feasibility of calculating the coal–oxygen diffusion properties during the low temperature oxidation process of lignite so as to predict its spontaneous combustion process. Coal samples were oxidized in air ambient under different temperatures. Scanning Electron Microscope was used to indicate the surface morphology changes of oxidization. Then, based on fractal theory and flow characteristics, the fractal dimension of gas diffusion in the pore ways was calculated under different temperature. Considering pore size distribution, connectivity distribution and Fick diffusion mechanisms, the relationship between the gas diffusivity change with pore area fractal dimension and porosity was investigated, and multiple linear equation of the coal–oxygen diffusion coefficients and pore parameters was obtained. Comparison between the experimental data and model prediction verifies the validity of the model. The research provides a theoretical basis for the prediction model of coal–oxygen diffusion law. | Xianliang Meng Mingqiang Gao Ruizhi Chu Guoguang Wu Qiang Fang | 2016 | Chinese Journal of Chemical Engineering2016，24，6： | 6 |
| 20 | Polyacrylic acid sodium salt film entrapped Ag-nanocubes as molecule traps for SERS detection显示文摘提高表面的拉曼光谱学(重量的单位) 是为踪迹化学药品的一种快分析技术;然而,吸附 analytes 要求活跃重量的单位底层,因此为底层与需要的亲密关系限制目标种类到那些。这里我们现在的联网的 polyacrylic 酸钠盐(PAAS ) 电影骗诱 Ag-nanocubes (作为 Ag-nanocubes@PAAS 表示了) 作为为有或没有高亲密关系的 analytes 的有效重量的单位底层。一次 analyte 水的答案在干燥 Ag-nanocubes@PAAS 底层上被扔,嗜酒的 PAAS 变得肿强迫 Ag-nanocubes 松开,当时在在 Ag-nanocubes 之中的空隙弥漫的 analytes。当弄干时, PAAS 缩小并且拉 Ag-nanocubes 回到他们的以前的聚集的状态,当 PAAS 网络为重量的单位察觉在在 Ag-nanocubes 之间的小差距耽搁 analytes 时。没有强壮的亲密关系,策略为 Ag 为不仅 singleanalytes 而且 multi-analytes 被证明有效,在环境在能吸附、非能吸附的污染物质的基于重量的单位的同时的 multi-analyte 察觉显示出它的潜力。 | Zhulin Huang Guowen Meng Qing Huang Bin Chen Fei Zhou Xiaoye Hu Yiwu Qian Haibin Tang Fangming Han Zhaoqin Chu | 2014 | Nano Research2014，7，8： | 6 |
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