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| 1 | Chemical composition and source apportionment of PM10 and PM2.5 in different functional areas of Lanzhou,China显示文摘To elucidate the air pollution characteristics of northern China, airborne PM_10(atmospheric dynamic equivalent diameter ≤ 10 μm) and PM_(2.5)(atmospheric dynamic equivalent diameter ≤ 2.5 μm) were sampled in three different functional areas(Yuzhong County,Xigu District and Chengguan District) of Lanzhou, and their chemical composition(elements, ions, carbonaceous species) was analyzed. The results demonstrated that the highest seasonal mean concentrations of PM_10(369.48 μg/m^3) and PM_(2.5)(295.42 μg/m^3) were detected in Xigu District in the winter, the lowest concentration of PM_(2.5)(53.15 μg/m^3) was observed in Yuzhong District in the fall and PM_10(89.60 μg/m^3) in Xigu District in the fall.The overall average OC/EC(organic carbon/elemental carbon) value was close to the representative OC/EC ratio for coal consumption, implying that the pollution of Lanzhou could be attributed to the burning of coal. The content of SNA(the sum of sulfate, nitrate,ammonium, SNA) in PM_(2.5)in Yuzhong County was generally lower than that at other sites in all seasons. The content of SNA in PM_(2.5)and PM_10 in Yuzhong County was generally lower than that at other sites in all seasons(0.24–0.38), indicating that the conversion ratios from precursors to secondary aerosols in the low concentration area was slower than in the area with high and intense pollutants. Six primary particulate matter sources were chosen based on positive matrix factorization(PMF) analysis, and emissions from dust, secondary aerosols, and coal burning were identified to be the primary sources responsible for the particle pollution in Lanzhou. | Xionghui Qiu Lei Duan Jian Gao Shulan Wang Fahe Chai Jun Hu Jingqiao Zhang Yaru Yun | 2016 | Journal of Environmental Sciences2016，28，2： | 33 |
| 2 | Ambient volatile organic compounds pollution in China显示文摘Owing to rapid economic and industrial development,China has been suffering from degraded air quality and visibility. Volatile organic compounds(VOCs)are important precursors to the formation of ground-level ozone and hence photochemical smog. Some VOCs adversely affect human health. Therefore,VOCs have recently elicited public concern and given new impetus to scientific interest. China is now implementing a series of polices to control VOCs pollution. The key to formulating policy is understanding the ambient VOCs pollution status. This paper mainly analyzes the species,levels,sources,and spatial distributions of VOCs in ambient air. The results show that the concentrations of ambient VOCs in China are much higher than those of developed countries such as the United States and Japan,especial benzene,which exceeds available standards. At the same time,the ozone formation potential(OFP)and secondary organic aerosol formation potential(SOAFP)of various VOCs are calculated. Aromatics and alkenes have much higher OFPs,while aromatics have higher SOAFP. The OFPs of ambient VOCs in the cities of Beijing,Guangzhou and Changchun are very high,and the SOAFP of ambient VOCs in the cities of Hangzhou,Guangzhou and Changchun are higher. | Xinmin Zhang Zhigang Xue Hong Li Li Yan Yuan Yang Yi Wang Jingchun Duan Lei Li Fahe Chai Miaomiao Cheng Weiqi Zhang | 2017 | Journal of Environmental Sciences2017，29，5： | 34 |
| 3 | Dextral strike-slip of Sanguankou-Niushoushan fault zone and extension of arc tectonic belt in the northeastern margin of the Tibet Plateau显示文摘Sanguankou-Niushoushan 差错(SGK-NSSF ) 的运动学的特征具有到弧的延期的理解的大意义在西藏高原的东北边缘的构造的带。用地调查和各种各样的数据收集方法,包括大规模地质的印射,典型地形学的测量,并且沉积阶层标明日期, SGK-NSSF 展出明显的右罢工滑倒特征并且因此不是一个左首的罢工滑倒差错,由以前的研究人员相信了,这被决定。这研究的结果证明地质的边界为古生代,中生代,和新生代时代都被差错右地打乱,与是类似的指责的排水量。在地志的效果的消除以后,差错的最大的罢工滑倒排水量被发现是 | LEI QiYun ZHANG PeiZhen ZHENG WenJun CHAI ChiZhang WANG WeiTao DU Peng YU JingXing | 2016 | Science China Earth Sciences2016，59，5： | 17 |
| 4 | Submucosal tunneling endoscopic resection: An effective and safe therapy for upper gastrointestinal submucosal tumors originating from the muscularis propria layer显示文摘AIM To evaluate the effectiveness and safety of submucosal tunneling endoscopic resection(STER) and compare its outcomes in esophageal and cardial submucosal tumors(SMTs) of the muscularis propria(MP) layer.METHODS From May 2012 to November 2017, 173 consecutive patients with upper gastrointestinal(GI) SMTs of the MP layer underwent STER. Overall, 165 patients were included, and 8 were excluded. The baseline characteristics of the patients and SMTs were recorded. The en bloc resection rate, complete resection rate,residual rate, and recurrence rate were calculated to evaluate the effectiveness of STER, and the complication rate was recorded to evaluate its safety. Effectiveness and safety outcomes were compared between esophageal and cardial SMTs.RESULTS One hundred and twelve men and 53 women with a mean age of 46.9 ± 10.8 years were included. The mean tumor size was 22.6 ± 13.6 mm. Eleven SMTs were located in the upper esophagus(6.7%), 49 in the middle esophagus(29.7%), 46 in the lower esophagus(27.9%), and 59 in the cardia(35.7%). Irregular lesions accounted for 48.5% of all lesions. STER achieved an en bloc resection rate of78.7%(128/165) for GI SMTs with an overall complication rate of 21.2%(35/165).All complications resolved without intervention or were treated conservatively without the need for surgery. The en bloc resection rates of esophageal and cardial SMTs were 81.1%(86/106) and 72.1%(42/59), respectively(P = 0.142), and the complication rates were 19.8%(21/106) and 23.7%(14/59), respectively,(P =0.555). The most common complications for esophageal SMTs were gas-related complications and fever, while mucosal injury was the most common for cardial SMTs.CONCLUSION STER is an effective and safe therapy for GI SMTs of the MP layer. Its effectiveness and safety are comparable between SMTs of the esophagus and cardia. | Chen Du Ning-Li Chai En-Qiang Ling-Hu Zhen-Juan Li Long-Song Li Jia-Le Zou Lei Jiang Zhong-Sheng Lu Jiang-Yun Meng Ping Tang | 2019 | World Journal of Gastroenterology2019，25，2： | 17 |
| 5 | Molecular diversity and genetic structure of 380 sweetpotato accessions as revealed by SSR markers显示文摘Sweetpotato, Ipomoea batatas(L.) Lam., is an important food crop widely cultivated in the world. Evaluation of genetic relationships among diverse cultivars and landraces is necessary for efficient exploitation of genetic diversity in the existing germplasm resources. In the present study, a collection of 380 sweetpotato accessions assembled from different agro-climatic zones of China and other countries were genotyped using 30 SSR primer pairs. Model-based structure analysis separated the germplasm into three populations, P1, P2 and P3, containing 228, 133 and 19 accessions, respectively, which was consistent with the results of phylogenic and principal component analysis(PCA). Analysis of molecular variance(AMOVA) revealed significant genetic differentiation among inferred populations, accounting for 16.47% of the total molecular variance, however, the differences between the regions were not significant, the total variation were due to the differences between the genotypes within the population. Pairwise fixation index(F ST) suggested that populations P1 and P3 had the highest differentiation, while populations P1 and P2 had the lowest differentiation. The diversity among populations was wide, which confirmed the genetic distinction of populations. Through comparing model-based structure and domestication-based classification, it was found that the accessions of population P1 mainly belonged to modern cultivars, and the accessions of populations P2 and P3 basically corresponded to landraces, by which we suggest that modern cultivars maybe had experienced a two-step domestication history. Our results illustrated clear genetic relationships among 380 sweetpotato accessions, exhibiting the potential of accelerating the process of future sweetpotato breeding program by molecular marker based parental selection. | YANG Xin-sun SU Wen-jin WANG Lian-jun LEI Jian CHAI Sha-sha LIU Qing-chang | 2015 | Journal of Integrative Agriculture2015，14，4： | 16 |
| 6 | Role of baicalin in regulating Toll-like receptor 2/4 after ischemic neuronal injury显示文摘 | LI Hui-ying YUAN Zhi-yi WANG Yu-gang WAN Hong-jiao HU Jun CHAI Yu-shuang LEI Fan XING Dong-ming DU Li-jun | 2012 | Chinese Medical Journal2012，，9： | 15 |
| 7 | Core-shell Au@MnO2 nanoparticles for enhanced radiotherapy via improving the tumor oxygenation显示文摘在稳固的肿瘤的本地组织缺氧经常导致抵抗到放射疗法(RT ) ,在哪个氧为提高 DNA 损坏的一个必要元素被电离引起放射。此处,我们开发了 gold@manganese 二氧化物(有聚乙烯乙二醇(木钉) 的 Au@MnO 2) 核心壳 nanoparticles 是的涂层在癌症治疗期间改进 RT 功效的一个新奇 radiosensitizing 代理人。在这 Au@MnO 2 nanostructure ,当金核心是著名 RT 时,交往与的 sensitizer X光检查为在 RT 下面杀死的改进癌症生产控告的粒子, MnO 2壳可以触发内长的 H 2在肿瘤微型环境到的 O 2产生氧并且克服 hypoxiaassociated RT 抵抗。是示威了由在 vitro 并且在 vivo 实验, Au@MnO 2-PEG nanoparticles 充当了有效 radiosensitizers 显著地在 RT 期间提高癌症治疗功效。而且, Au@MnO 2-PEG 的明显的副作用都没在老鼠被观察。因此,我们的工作为 hypoxic 肿瘤的提高的 RT 治疗与潜力介绍 radiosensitizer 的一种新类型。 | Xuan Yi Lei Chen Xiaoyan Zhong Roulin Gao Yitao Qian Fan Wu Guosheng Song Zhifang Chai Zhuang Liu Kai Yang | 2016 | Nano Research2016，9，11： | 12 |
| 8 | Comparison of endoscopic ultrasound, computed tomography and magnetic resonance imaging in assessment of detailed structures of pancreatic cystic neoplasms显示文摘AIM To evaluate the advantages of endoscopic ultrasound(EUS) in the assessment of detailed structures of pancreatic cystic neoplasms(PCNs) compared to computed tomography(CT) and magnetic resonance imaging(MRI).METHODS All patients with indeterminate PCNs underwent CT, MRI, and EUS. The detailed information, including size, number, the presence of a papilla/nodule, the presence of a septum, and the morphology of the pancreatic duct of PCNs were compared among the three imaging modalities. The size of each PCN was determined using the largest diameter measured. A cyst consisting of several small cysts was referred to as a motherdaughter cyst. Disagreement among the three imaging modalities regarding the total number of mother cysts resulted in the assumption that the correct number was the one in which the majority of imaging modalities indicated.RESULTS A total of 52 females and 16 males were evaluated. The median size of the cysts was 42.5 mm by EUS, 42.0 mm by CT and 38.0 mm by MRI; there was no significant difference in size as assessed among the three imaging techniques. The diagnostic sensitivity and ability of EUS to classify PCNs were 98.5%(67/68) and 92.6%(63/68), respectively. These percentages were higher than those of CT(73.1%, P < 0.001; 17.1%, P < 0.001) and MRI(81.3%, P = 0.001; 20.3%, P < 0.001). EUS was also able to better assess the number of daughter cysts in mother cysts than CT(P = 0.003); however, there was no significant difference between EUS and MRI in assessing mother-daughter cysts(P = 0.254). The papilla/nodule detection rate by EUS was 35.3%(24/68), much higher than those by CT(5.8%, 3/52) and MRI(6.3%, 4/64). The detection rate of the septum by EUS was 60.3%(41/68), which was higher than those by CT(34.6%, 18/52) and by MRI(46.9%, 30/64); the difference between EUS and CT was significant(P = 0.02). The rate of visualizing the pancreatic duct using EUS was 100%, whereas using CT and MRI it was less than 10%.CONCLUSION EUS helps visualize the detailed structures of PCNs and has many advantages over CT and MRI. EUS is valuable in the diagnosis and assessment of PCNs. | Chen Du Ning-Li Chai En-Qiang Linghu Hui-Kai Li Li-Hua Sun Lei Jiang Xiang-Dong Wang Ping Tang Jing Yang | 2017 | World Journal of Gastroenterology2017，23，17： | 11 |
| 9 | Co调变MoS2催化剂的作用本质及其FCC汽油选择性加氢脱硫机理显示文摘采用含硫前驱体四硫代钼酸铵直接构建MoS2催化剂,通过调变Co/Mo原子比深入认识Co调变MoS2催化剂的作用本质及其FCC汽油选择性加氢脱硫机理。借助XRD、HRTEM、XPS、H2-TPR和Py-FTIR表征发现,Co/Mo原子比能够影响催化剂的活性相微观结构组成,从而影响催化剂的加氢脱硫活性和选择性。当Co/Mo(atomicratio)<0.2时,助剂Co原子倾向于占据MoS2相的边角位而形成CoMoS活性相,明显提高了催化剂的加氢脱硫活性;当0.20.6时,过量的Co会形成大颗粒的Co9S8相,阻碍硫化物和烯烃与催化剂活性中心的接触,从而降低催化剂的活性和选择性。 | LIU Bin LIU Lei CHAI Yong-ming ZHAO Jin-chong LIU Chen-guang 刘宾 刘蕾 柴永明 赵晋翀 刘晨光 | 2018 | 燃料化学学报2018，46，4： | 9 |
| 10 | INFLUENCE OF SURFACTANT ON TWO-PHASE FLOW REGIME AND PRESSURE DROP IN UPWARD INCLINED PIPES显示文摘The influence of a surfactant on the two-phase flow regime and the pressure drop in upward inclined pipes is investigated for various gas/liquid flow rates.The air/water and air/100 ppm sodium dodecyl sulphate aqueous solution are used as the working fluids.The influence of the surfactant on the two-phase flow regime in upward inclined pipes is investigated using the electrical tomographic technique.For 0o,2.5o and 5o pipe inclinations,the surfactant has obvious effect on the transition from the stratified wavy flow to the annular flow,and the range of the stratified smooth flow regime is also extended to higher gas velocities.For 10o pipe inclination,no stratified flow regime is observed in the air/water flow.In the air/surfactant solution system,however,the stratified flow regime can be found in the range of and.For all inclination angles,the changes of the pressure gradient characteristics are accompanied with the flow pattern transitions.Adding surfactant in a two-phase flow would reduce the pressure gradient significantly in the slug flow and annular flow regimes.In the annular flow regime,the pressure gradient gradually becomes free of the influence of the upward inclined angle,and is only dependent on the property of the two-phase flow. | XIA Guo-dong CHAI Lei | 2012 | Journal of Hydrodynamics2012，24，1： | 8 |
| 11 | Determination of rare earth elements in plant protoplasts by MAA显示文摘A preliminary study on the speciation of rare earth elements in plant cells has been carried out by molecular activation analysis (MAA). Mesophyll protoplasts of Brassica napus were isolated by enzymatic digestion. After being washed with isosmotic solution containing EDTA for several times, the protoplasts were purified by gradient centrifugation. Then the concentration of rare earth elements (REEs) in the protoplasts was determined by neutron activation analysis. The result shows that REEs can enter the cells of the plant. | ZHANG Zhiyong WANG Yuqi SUN Jingxin LI Fuliang CHAI Zhifang XU Lei LI Xin CAO Guoyin | 2000 | Chinese Science Bulletin2000，45，16： | 8 |
| 12 | Effect of Yang-activating and stasis-eliminating decoction from Traditional Chinese Medicine on intestinal mucosal permeability in rats with ulcerative colitis induced by dextran sulfate sodium显示文摘OBJECTIVE: To evaluate the effect of decoction prepared with Yang-activating and stasis-eliminating medicinals from Traditional Chinese Medicine(TCM) on the intestinal mucosal permeability in rats with ulcerative colitis induced by dextran sulfate sodium(DSS).METHODS: Totally 55 male Wistar rats(body weight of 170-190 g) were randomly divided into the blank group(n = 10) and the model duplication group(n = 45). The blank group was not intervened, while the other was modeled with 5% dextran sulfate sodium by gavaging in a dosage of4 m L per day to induce ulcerative colitis, a total of7 days. Then, the model rats were divided into model blank group, mesalazine group and TCM group,and each group was consisted of 15 rats. They were given retention enema 10 min with normal saline,mesalazine enema(0.036 g/m L), and Yang-activating and stasis-eliminating decoction [0.54 g/m L of a decoction boiled by Puhuang(Pollen Typhae), Xiebai(Bulbus Allii Macrostemonis) and Wulingzhi(Faeces Trogopteri)] for 10 days respectively. Afterwards,all of the rats were evaluated by disease activity index(DAI), histological changes of distal colon, expression of occludin protein and ultrastructure of intestinal epithelial cells. Furthermore, ratio of lactulose to mannitol(L/M) discharged in urine was evaluated.RESULTS: Comparing the results between TCM and model control groups, scores of DAI and histological lesions decreased significantly(P = 0.000 <0.01), ultrastructures of intestinal epithelial cells and tight junctions were more complete. The expression of occludin protein(P = 0.001 < 0.01) increased while the L/M value decreased significantly(P = 0.000 < 0.01) in TCM group. There was no statistical difference between the TCM and mesalazine groups in results of each item(P > 0.05).CONCLUSION: The decoction prepared with Yang-activating and stasis-eliminating TCM medicianls can restore intestinal mucosal epithelial cells and tight junctions the model rats with ulcerative colitis; it can reduce histological lesions and protect the permeability of intestinal mucosa barrier in the rats as well. | Shi Lijie Shi Lei Liu Leilei Feng Xiuxian Wang Jing Yang Qiang Chai Shiwei Gou Jing Zang Fenglin He Sufei | 2017 | Journal of Traditional Chinese Medicine2017，37，4： | 7 |
| 13 | MANUFACTURER'S CHANNEL SELECTION CONSIDERING CARBON EMISSION REDUCTION AND REMANUFACTURING显示文摘 | Lei Yang Guoyu Wang Yina Chai | 2018 | Journal of Systems Science and Systems Engineering2018，27，4： | 7 |
| 14 | Analysis of flow and heat transfer characteristics of micro-pin fin heat sink using silver nanofluids显示文摘Silver nanofluids with three different volume fractions are prepared by a one-step chemical reduction method(Ultra-sound-assisted Membrane Reaction(UAMR)).The convective heat transfer and friction characteristics of silver nanofluid in micro-pin fin heat sink are investigated experimentally.The results indicate that the pressure drops of nanofluids with different volume fractions have little difference.Compared to the base fluid(polyvinylpyrrolidone(PVP) solution),the pressure drop of nanofluids increases slightly at the same volume flow rate.When the flow rate is small,the increment is not obvious.The in-troduction of surfactant increases the fluid viscosity,so the pressure drops of nanofluids are larger than those of pure water,under the same flow rate.However,the maximum difference is no more than 10%.The volume fraction of silver nanoparticles significantly affects the convection heat transfer coefficient of micro-pin fin heat sink.The presence of nanoparticles improves significantly the heat transfer performance.However,high viscosity of the nanofluids hinders the heat transfer strengthening effect of nanofluids.In the present work,when the volume fraction of silver particles reaches to 0.012%,the thermal resistance of nanofluid gradually becomes lower than that of deionized water,which indicates the integrated heat transfer enhancement of nanofluids. | ZHOU MingZheng XIA GuoDong CHAI Lei LI Jian ZHOU LiJun | 2012 | Science China(Technological Sciences)2012，55，1： | 6 |
| 15 | Lingbao Huxin Pill Alleviates Apoptosis and Inflammation at Infarct Border Zone through SIRT1-Mediated FOXO1 and NF-κB Pathways in Rat Model of Acute Myocardial Infarction显示文摘Objective To investigate whether Lingbao Huxin Pill(LBHX)protects against acute myocardial infarction(AMI)at the infarct border zone(IBZ)of myocardial tissue by regulating apoptosis and inflammation through the sirtuin 1(SIRT1)-mediated forkhead box protein O1(FOXO1)and nuclear factor-κB(NF-κB)signaling pathways.Methods Six-week-old Wistar rats with normal diet were randomized into the sham,the model,Betaloc(0.9 mg/kg daily),LBHX-L(0.45 mg/kg daily),LBHX-M(0.9 mg/kg daily),LBHX-H(1.8 mg/kg daily),and LBHX+EX527(0.9 mg/kg daily)groups according to the method of random number table,13 in each group.In this study,left anterior descending coronary artery(LADCA)ligation was performed to induce an AMI model in rats.The myocardial infarction area was examined using a 2,3,5-triphenyltetrazolium chloride solution staining assay.A TdT-mediated dUTP nick-end labeling(TUNEL)assay was conducted to assess cardiomyocyte apoptosis in the IBZ.The histopathology of myocardial tissue at the IBZ was assessed with Heidenhain,Masson and hematoxylineosin(HE)staining assays.The expression levels of tumor necrosis factorα(TNF-α),interleukin(IL)-6,IL-1β,and intercellular adhesion molecule-1 were measured using enzyme-linked immunosorbent assays(ELISAs).The mRNA expressions of SIRT1 and FOXO1 were detected by real-time qPCR(RT-qPCR).The protein expressions of SIRT1,FOXO1,SOD2,BAX and NF-κB p65 were detected by Western blot analysis.Results The ligation of the LADCA successfully induced an AMI model.The LBHX pretreatment reduced the infarct size in the AMI rats(P<0.01).The TUNEL assay revealed that LBHX inhibited cardiomyocyte apoptosis at the IBZ.Further,the histological examination showed that the LBHX pretreatment decreased the ischemic area of myocardial tissue(P<0.05),myocardial interstitial collagen deposition(P<0.05)and inflammation at the IBZ.The ELISA results indicated that LBHX decreased the serum levels of inflammatory cytokines in the AMI rats(P<0.05 or P<0.01).Furthermore,Western blot analysis revealed that the LBHX pretreatment upregulated the protein levels of SIRT1,FOXO1 and SOD2(P<0.05)and downregulated NF-κB p65 and BAX expressions(P<0.05).The RT-qPCR results showed that LBHX increased the SIRT1 mRNA and FOXO1 mRNA levels(P<0.05).These protective effects,including inhibiting apoptosis and alleviating inflammation in the IBZ,were partially abolished by EX527,an inhibitor of SIRT1.Conclusion LBHX could protect against AMI by suppressing apoptosis and inflammation in AMI rats and the SIRT1-mediated FOXO1 and NF-κB signaling pathways were involved in the cardioprotection effect of LBHX. | TAN Yu BIE Yu-long CHEN Li ZHAO Yi-han SONG Lei MIAO Li-na YU Yan-qiao CHAI Hua MA Xiao-juan SHI Da-zhuo | 2022 | Chinese Journal of Integrative Medicine2022，28，4： | 6 |
| 16 | Straw strip mulching in a semiarid rainfed agroecosystem achieves winter wheat yields similar to those of full plastic mulching by optimizing the soil hydrothermal regime显示文摘Straw strip mulching(SM)is a new mulching technology.From 2012 to 2018,SM’s effects on soil moisture and temperature and production performances were compared with other mulching practices,using three treatments:full-cover plastic mulch(PM),no mulch with wheat sown in rows as the control(CK),and SM with 50%to 59%of the field area mulched.Compared with CK,on average over six growing seasons,SM and PM increased grain yield by 27.0%and 21.7%,straw yield by 21.6%and 22.6%,kernels ha;by 26.6%and 19.0%,net income by 29.8%and-25.0%,soil temperature at 5 cm by-1.5°C and 0.2°C from overwintering to maturity,and soil water storage at 0–200 cm by 25 and 22 mm,respectively.The increase in soil moisture in SM and PM was greater in the early period(overwintering to jointing)than in the later period(booting to maturity)and at 0 to 120 cm than at 120–200 cm in the early period.Although the mean evapotranspiration of whole growth period across six seasons was similar among treatments,SM and PM increased water consumption during the key formation period of yield components after overwintering by 16 and 32 mm,respectively,while reducing it before overwintering.Compared with CK,SM and PM had the effects of warming during overwintering and cooling after jointing.By increasing water consumption after overwintering and ratio of transpiration to evapotranspiration and providing favorable soil temperature for multiple growth stages and more sufficient soil moisture,SM and PM promoted vegetative growth and increased kernels ha^(-1),the main mechanisms by which SM and PM increased grain yield relative to CK.Relative to PM,SM is a more economically beneficial and environment-friendly technology for dryland wheat production. | Yuwei Chai Qiang Chai Rui Li Yawei Li Changgang Yang Hongbo Cheng Lei Chang Shouxi Chai | 2022 | The Crop Journal2022，10，3： | 6 |
| 17 | Gene-lndexed Mutations in Maize显示文摘 | Xiaoduo Lu Jisheng Liu Wen Ren Qun Yang Zhenguang Chai Rumei Chen Lei Wang Jun Zhao Zhihong Lang Haiyang Wang Yunliu Fan Jiuran Zhao Chunyi Zhang | 2018 | Molecular Plant2018，11，3： | 4 |
| 18 | Novel parameter for assessment of left atrial size in patients with hypertension: ratio of left atrial volume to left ventricular volume显示文摘背景左 atrial 增大作为心脏舒张的机能障碍的一个更柔韧的标记被建议了。我们假设到左室的体积(LAV/LVV ) 的左 atrial 体积的比率可能是更合理的思考,这与高血压在病人离开了 atrial 增大,因为高血压的病人有经常伴有心脏舒张的机能障碍的左室的同心改变的一个特征。学习是决定 LAV/LVV 是否能被用作一个新参数估计的这的目的在在 LAV/LVV 和心脏舒张的 dysfunction.Methods 之间的高血压的病人和关系离开了 atrial 尺寸有高血压和 43 正常控制的 91 个病人被学习。高血压的病人被分到正常的墙(NW ) 和 hypertrophic 墙(HW ) 组。左 atrial 直径(男孩) ,洗室,左 atrial 体积索引(LAVi ) , LVV 和 LAV/LVV 被 2-dimensional echocardiography 和实时 3-dimensional echocardiography 测量并且计算。上述所有参数被用来评估左中庭的尺寸。到侧面的僧帽形的体环(E/E') 的山峰 E' 速度的僧帽形的阀门流入的山峰 E 速度的比率被脉搏 Doppler 和织物 Doppler 测量。这个参数被用来评估心脏舒张的功能。结果在高血压的组的男孩,洗室, LAVi, LAV/LVV 和 E/E' 比在正常的组的那些显著地高(P < 0.05 或 0.01 ) ,并且在 HW 组的那些比在 NW 组的那些显著地高(P < 0.05 或 0.01 ) 。E/E' 与洗室, LAVi 和 LAV/LVV 有积极关联。在 E/E' 和 LAV/LVV 之间的关联系数在 E/E' 之间比那相对高,男孩或 LAVi.Conclusion LAV/LVV 可以被用作一个新索引与心脏舒张的机能障碍在高血压的病人评估左 atrial 尺寸。 | LI Yue CHAI Liang ZHANG Yun LI Lei | 2009 | Chinese Medical Journal2009，，19： | 3 |
| 19 | Processing Environmental Stimuli in Paranoid Schizophrenia:Recognizing Facial Emotions and Performing Executive Functions显示文摘Objective To study the contribution of executive function to abnormal recognition of facial expressions of emotion in schizophrenia patients. Methods Abnormal recognition of facial expressions of emotion was assayed according to Japanese and Caucasian facial expressions of emotion (JACFEE), Wisconsin card sorting test (WCST), positive and negative symptom scale, and Hamilton anxiety and depression scale, respectively, in 88 paranoid schizophrenia patients and 75 healthy volunteers. Results Patients scored higher on the Positive and Negative Symptom Scale and the Hamilton Anxiety and Depression Scales, displayed lower JACFEE recognition accuracies and poorer WCST performances. The JACFEE recognition accuracy of contempt and disgust was negatively correlated with the negative symptom scale score while the recognition accuracy of fear was positively with the positive symptom scale score and the recognition accuracy of surprise was negatively with the general psychopathology score in patients. Moreover, the WCST could predict the JACFEE recognition accuracy of contempt, disgust, and sadness in patients, and the perseverative errors negatively predicted the recognition accuracy of sadness in healthy volunteers. The JACFEE recognition accuracy of sadness could predict the WCST categories in paranoid schizophrenia patients. Conclusion Recognition accuracy of social-/moral emotions, such as contempt, disgust and sadness is related to the executive function in paranoid schizophrenia patients, especially when regarding sadness. | YU Shao Hua ZHU Jun Peng XU You ZHENG Lei Lei CHAI Hao HE Wei LIU Wei Bo LI Hui Chun WANG Wei | 2012 | Biomedical and Environmental Sciences2012，25，6： | 3 |
| 20 | Identification of Nonstructural Protein 8 as the N-Terminus of the RNA-Dependent RNA Polymerase of Porcine Reproductive and Respiratory Syndrome Virus显示文摘Porcine reproductive and respiratory syndrome virus (PRRSV) is a member within the family Arteriviridae of the order Nidovirales. Replication of this positive-stranded RNA virus within the host cell involves expression of viral replicase proteins encoded by two ORFs, namely ORF1 a and ORF1 b. In particular, translation of ORF1 b depends on a-1-ribosomal frameshift strategy. Thus, nonstructural protein 9 (nsp9), the first protein within ORF1 b that specifies the function of the viral RNA-dependent RNA polymerase, is expressed as the C-terminal extension of nsp8, a small nsp that is encoded by ORF1 a. However, it has remained unclear whether the mature form of nsp9 in virus-infected cells still retains nsp8,addressing which is clearly critical to understand the biological function of nsp9. By taking advantage of specific antibodies to both nsp8 and nsp9, we report the following findings. (1) In infected cells, PRRSV nsp9 was identified as a major product with a size between 72 and 95 k Da (72–95 KDa form), which exhibited the similar mobility on the gel to the in vitro expressed nsp8–9 ORF1 b, but not the ORF1 b-coded portion (nsp9 ORF1 b). (2) The antibodies to nsp8, but not to nsp7 or nsp10, could detect a major product that had the similar mobility to the 72–95 KDa form of nsp9. Moreover, nsp9 could be co-immunoprecipitated by antibodies to nsp8, and vice versa. (3) Neither nsp4 nor nsp2 PLP2 was able to cleave nsp8–nsp9 in vitro. Together, our studies provide experimental evidence to suggest that nsp8 is an N-terminal extension of nsp9.Our findings here paves way for further charactering the biological function of PRRSV nsp9. | Yuanyuan Liu Yunhao Hu Yue Chai Liping Liu Jiangwei Song Shaochuan Zhou Jia Su Lei Zhou Xinna Ge Xin Guo Jun Han Hanchun Yang | 2018 | Virologica Sinica2018，33，5： | 3 |
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