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| 1 | 在直肠的癌症的磁性的回声成像调查结果的临床的意义显示文摘 Staging of rectal cancer is essential to help guide clini-cians to decide upon the correct type of surgery and determine whether or not neoadjuvant therapy is indicated. Magnetic resonance imaging (MRI) is currently one of the most accurate modalities on which to base treatment decisions for patients with rectal cancer. MRI can accurately detect the mesorectal fascia, assess the invasion of the mesorectum or surrounding organs and predict the circumferential resection margin. Although nodal disease remains a difficult radiological diagnosis, new lymphographic agents and diffusion weighted imaging may allow identification of metastatic nodes by criteria other then size. In light of this, we have reviewed the literature on the accuracy of specific MRI findings for staging the local extent of primary rectal cancer. The aim of this review is to establish a correlation between MRI findings, prognosis, and available treatment options. | Charles F Bellows Bernard Jaffe Lorenzo Bacigalupo Salvatore Pucciarelli Guiseppe Gagliardi | 2011 | World Journal of Radiology2011，3，4： | 19 |
| 2 | Autoimmune hepatitis and anti-tumor necrosis factor alpha therapy:A single center report of 8 cases显示文摘This article describes cases of anti-tumor necrosis factor(TNF)-α-induced autoimmune hepatitis and evaluates the outcome of these patients in relation to their immunosuppressive strategy. A retrospective analysis of medical records was performed in our center, in order to detect cases of autoimmune hepatitis(AIH) associated with anti-TNF biologic agents. We describe and analyze eight cases of AIH following anti-TNF therapy, 7 with infliximab and 1 with adalimumab. A distinction should be made between induction of autoimmunity and clinically evident autoimmune disease. Liver biopsy is useful in detecting the role of the TNF-α antagonist in the development of AIH. The lack of relapse after discontinuing immunosuppressive therapy favors, as in this case series, an immune-mediated drug reaction as most patients with AIH have a relapse after treatment is suspended. Although AIH related to anti-TNF therapy is rare, a baseline immunological panel along with liver function tests should be performed in all patients with autoimmune disease before starting biologics. | Susana Rodrigues Susana Lopes Fernando Magro Hélder Cardoso Ana Maria Horta e Vale Margarida Marques Eva Mariz Miguel Bernardes Joanne Lopes Fátima Carneiro Guilherme Macedo | 2015 | World Journal of Gastroenterology2015，21，24： | 9 |
| 3 | Heavy metal removal from sediments by biosurfactants显示文摘 | Catherine N Mulligan Raymond N Yong Bernard F Gibbs | 2001 | Journal of Hazardous Materials2001，，1： | 2 |
| 4 | Axillary dissection versus no axillary dissection in patients with sentinel-node micrometastases (IBCSG 23–01): a phase 3 randomised controlled trial显示文摘 | Viviana Galimberti Bernard F Cole Stefano Zurrida Giuseppe Viale Alberto Luini Paolo Veronesi Paola Baratella Camelia Chifu Manuela Sargenti Mattia Intra Oreste Gentilini Mauro G Mastropasqua Giovanni Mazzarol Samuele Massarut Jean-Rémi Garbay Janez Zgajn | 2013 | Lancet Oncology2013，，4： | 2 |
| 5 | Limiting steps of hydrogen production in Chlamydomonas reinhardtii and Synechocystis PCC 6803 as analysed by light- induced gas exchange transients显示文摘 | Cournac L Mus F Bernard L | 2002 | Inter J Hydrogen Energy2002，27，： | 1 |
| 6 | Identification of a new natural Ara h 6 isoform and of its proteolytic product as major allergens in peanut显示文摘 | BERNARD H MONDOULET L DRUMARE M F | 2007 | J Agric Food Chore2007，55，： | 1 |
| 7 | Effect of tensile cracking on diffusivity of mortar: 3D numerical modeling显示文摘 | KAMALI-BERNARD S BERNARD F | 2009 | Computational Materials Science2009，47，： | 1 |
| 8 | Simulation of Agroforestry Systems With Sugarcane in Piracicaba,Brazil显示文摘 | PINTO L F G BERNARDES M S NOORDWIJK M V | 2005 | Agricultural Systems2005，86，3： | 1 |
| 9 | Cholinergic me-sencephalic neurons are involved in gait and postural disorders in Parkinson disease显示文摘 | Karachi C Grabli D Bernard F A | 2010 | J Clin Invest2010，120，8： | 1 |
| 10 | Public transportation line positions and headways for minimum user and system cost in a radial case 显示文摘 | Byrne Bernard F | 1995 | Transportation Research Record1995，19，7： | 1 |
| 11 | Large-scale transient expression in mammalian cells for recombinant protein production 显示文摘 | Wurm F Bernard A | 1999 | Current Opinion in Biotechnology1999，10，2： | 1 |
| 12 | Greenhouse gas emissions and climate change: causes and consequences observed for agriculture and animal production显示文摘 | Bernard Seguin B Soussana J F | 2008 | Courrier De l''Environnement De I''INRA2008，55，1： | 1 |
| 13 | Use of recombinant human DNase for processing of athawed umbilical cord blood transplant in a patient with relapsed acute lymphoblastic leukemia显示文摘 | Beck C Bernard F | 2002 | Ann Hematol2002，81，： | 1 |
| 14 | Shape Distribution显示文摘 | Robert O Thomas F Bernard C | 2002 | ACM Transactions on Graphics2002，21，4： | 1 |
| 15 | In vitro metabolism of ginsennosides by ginseng root pathogen Pytium irregulae显示文摘 | Lina F Yousef M Bernards A | 2006 | Phytochemistry2006，67，： | 1 |
| 16 | Oyster hemocytes express a proline-rich peptide displaying synergistic antimicrobial activity with a defensin 显示文摘 | GUEGUEN Y BERNARD R JULIE F | 2009 | Molecular Immunology2009，46，4： | 1 |
| 17 | Differential behaviors of Staphylococcus aureus and Escherichia coli type Ⅱ DNA topoisomerases显示文摘 | Blanche F Cameron B Bernard F X | 1996 | Antimicrobial Agents and Chemotherapy1996，40，12： | 1 |
| 18 | Emphysema and pneumothorax after percutaneous tracheostomy: case reports and an anatomic study显示文摘 | Bernard G F Jacques A van V Jan G K | 2004 | Chest2004，125，： | 1 |
| 19 | Tumor growth rate determines the timing of optimal chronomodulated treatment schedules显示文摘 | Bernard S Bernard BC Levi F | 2010 | PLoS Comput Biol2010，6，10： | 1 |
| 20 | Minimizing the risk of reporting false positives in large-scale RNAi screens显示文摘 | Echeverri C.J Beachy P.A Baum B Boutros M Buchholz F Chanda K K Downward J Ellenberg J Fraser A.G Hacohen N Hahn W.C Jackson A.L Kiger A Linsley P.S Lum L Ma Y Mathey-Prevot B Root D.E Sabatini D.M Taipale J Perrimon N and Bernards R | | 0，，： | 1 |
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