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| 1 | Long-term albumin infusion improves survival in patients with cirrhosis and ascites: An unblinded randomized trial显示文摘瞄准:在幸存上调查长期的白朊管理的效果,腹水的复发和另外的复杂并发症的发作。方法:为第一发作的腹水招收的 100 个连续病人被使随机化加人的白朊收到利尿剂第一年和 25 g 里的 25 g/wk 每二 wk 此后(组 1 ) 或利尿剂独自一个(组 2 ) 。没有肝移植,主要端点是幸存。第二等的端点是腹水的复发和另外的复杂并发症的出现。结果:中部的后续是 84 (2-120 ) 瞬间。对待白朊的病人有显著地更大的累积幸存率(Breslow test=7.05, P=0.0078 ) 并且腹水复发的更低的概率(51% 对 94% , P<0.0001 ) 。长期的白朊注入导致了 16 瞬间的幸存的吝啬的增加。结论:在第一发作的腹水以后的长期的白朊管理显著地改进病人的幸存并且减少腹水复发的风险。 | Roberto Giulio Romanelli Giorgio La Villa Giuseppe Barletta Francesco Vizzutti Fabio Lanini Umberto Arena Vieri Boddi Roberto Tarquini Pietro Pantaleo Paolo Gentilini Giacomo Laffi | 2006 | World Journal of Gastroenterology2006，12，9： | 22 |
| 2 | Definition and diagnostic criteria of refractory ascites and hepatorenal syndrome in cirrhosis显示文摘 | V Arroyo P Gines AL Gerbes FJ Dudley P Gentilini G Laffi TB Reynolds H Ring-Larsen J Scholmerich | 1996 | Hepatology1996，，1： | 3 |
| 3 | Axillary dissection versus no axillary dissection in patients with sentinel-node micrometastases (IBCSG 23–01): a phase 3 randomised controlled trial显示文摘 | Viviana Galimberti Bernard F Cole Stefano Zurrida Giuseppe Viale Alberto Luini Paolo Veronesi Paola Baratella Camelia Chifu Manuela Sargenti Mattia Intra Oreste Gentilini Mauro G Mastropasqua Giovanni Mazzarol Samuele Massarut Jean-Rémi Garbay Janez Zgajn | 2013 | Lancet Oncology2013，，4： | 2 |
| 4 | Eviendep~ reduces number and size of duodenal polyps in familial adenomatous polyposis patients with ileal pouchanal anastomosis显示文摘AIM:To evaluate if 3 mo oral supplementation with Eviendep was able to reduce the number of duodenal polyps in familial adenomatous polyposis(FAP)patients with ileal pouch-anal anastomosis(IPAA).METHODS:Eleven FAP patients with IPAA and duodenal polyps were enrolled.They underwent upper gastrointestinal(GI)endoscopy at the baseline and after 3 mo of treatment.Each patient received 5 mg Eviendep twice a day,at breakfast and dinner time,for3 mo.Two endoscopists evaluated in a blinded manner the number and size of duodenal polyps.Upper GI endoscopies with biopsies were performed at the baseline(T0)with the assessment of the Spigelman score.Polyps>10 mm were removed during endoscopy and at the end of the procedure a new Spigelman score was determined(T1).The procedure was repeated 3 mo after the baseline(T2).Four photograms were examined for each patient,at T1 and T2.The examined area was divided into 3 segments:duodenal bulb,second and third portion duodenum.Biopsy specimens were taken from all polyps>10 mm and from all suspicious ones,defined by the presence of a central depression,irregular surface,or irregular vascular pattern.Histology was classified according to the updated Vienna criteria.RESULTS:At baseline the mean number of duodenal detected polyps was 27.7 and mean sizes were 15.8mm;the mean Spigelman score was 7.1.After polypectomy the mean number of duodenal detected polyps was 25.7 and mean sizes were 7.6 mm;the mean Spigelman score was 6.4.After 3 mo of Eviendep bid,all patients showed a reduction of number and size of duodenal polyps.The mean number of duodenal polyps was 8(P=0.021)and mean size was 4.4 mm;the mean Spigelman score was 6.6.Interrater agreement was measured.Lesions>1 cm found a very good degree of concordance(kappa 0.851)and a good concordance was as well encountered for smaller lesions(kappa 0.641).CONCLUSION:Our study demonstrated that shortterm(90 d)supplementation with Eviendep in FAP patients with IPAA and with recurrent adenomas in the duodenal mucosa,resulted effective in reducing polyps number of 32%and size of 51%. | Carlo Calabrese Chiara Praticò Andrea Calafiore Maurizio Coscia Lorenzo Gentilini Gilberto Poggioli Paolo Gionchetti Massimo Campieri Fernando Rizzello | 2013 | World Journal of Gastroenterology2013，19，34： | 2 |
| 5 | Definition and diagnostic criteria of refractory ascites and hepatorenal syndrome in cirrhosis显示文摘 | V Arroyo P Gines AL Gerbes FJ Dudley P Gentilini G Laffi TB Reynolds H Ring-Larsen J Scholmerich | 1996 | Hepatology1996，，1： | 2 |
| 6 | Evaluation of intracellular signalling pathways in response to insulin-like growth factor I in apoptotie-resistant activated human hepatic stellate cells显示文摘 | Gentilini A Lottini B Brogi M | 2009 | Fibrogenesis Tissue Repair2009，2，： | 1 |
| 7 | Endocannabinoid system reg-ulates migration of endometrial stromal cells via cannabinoid receptor Ithrough the activation of PI3K and ERK1/2 pathways显示文摘 | Gentilini D Besana A Vigano P | 2010 | Fertil Steril2010，93，8： | 1 |
| 8 | Feeding the gut early after digestive surgery:results of a nine-year experience显示文摘 | Braga M Gianotti L Gentilini O | 2002 | Clin Nutr2002，21，1： | 1 |
| 9 | Hemodynamic alterations in liver cirrhosis 显示文摘 | Villa G L Gentilini P | 2008 | Mol Aspects Med2008，29，12： | 1 |
| 10 | Early postoperative enteral nutrition improves gut oxygenation and reduces costs compared with total parenteral nutrition显示文摘 | Braga M Gianotti L Gentilini O | 2001 | Crit Care Med2001，29，： | 1 |
| 11 | Early postoperative enteralnutrition improves gut oxygenateon and reduces costs compared with total parenteral nutriation 显示文摘 | Braga M Gianotti Gentilini O | 2001 | Crit Care Med2001，29，2： | 1 |
| 12 | Feeding the gut early after digestive surgery : results of a nine-year expe- rience显示文摘 | Braga M Gianotti L Gentilini O | 2002 | Clin Nutr2002，21，1： | 1 |
| 13 | PI3K/Akt and ERK1/ 2 signalling pathways are involved in endometrial cell migration induced by 17beta-estradiol and growth factors 显示文摘 | Gentilini D Busaeca M Di Francesco S | 2007 | Mol Hum Re- prod2007，13，5： | 1 |
| 14 | Effects of maximally tolerated oral therapy on the six-minute walking test in patlents with chronic congestive heart failure secondary to either ischemic or idiopathic dilated cardiomyopathy显示文摘 | Gualeni A D Aloia A Gentilini A | 1998 | Am J Cardiol1998，81，11： | 1 |
| 15 | Endocannabinoid system regulates migration of endometrial stromal cells via cannabinoid receptor 1 through the activation of PI3K and ERK1/2 pathways 显示文摘 | Gentilini D Besana A Vigano P | 2010 | Fertil Steril2010，93，8： | 1 |
| 16 | Obstructive sleep apnoea is improved by a prolonged treatment of gastroesophageal reflux with omeprazole 显示文摘 | Bortolotti M Gentilini L Morselli C | 2006 | Dig Liver Dis2006，38，2： | 1 |
| 17 | Fractionation of glycoside precursors of aroma in grapes and wine显示文摘 | Mateo J J Gentilini N Huerta T | 1997 | Journal of Chromatography A1997，，8： | 1 |
| 18 | Endometrial stromal cells from women with endometriosis reveal peculiar migratory behavior in response to ovarian steroids 显示文摘 | Gentilini D Vigano P Somigliana E | 2010 | Fertil Steril2010，93，3： | 1 |
| 19 | Transform ing growth factor-β1 regulates platelet-derived growth factor receptor β subunit in human liver fatstoring cells显示文摘 | Pinzan M Gentilini A Caligiuri A | 1995 | Hepatology1995，21，1： | 1 |
| 20 | Artificial nutrition after pancreatoduodenectomy显示文摘 | Gianotti L Braga M Gentilini O | 2000 | Pancreas2000，34，21： | 1 |
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