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| 1 | Extended surgical resection for xanthogranulomatous cholecystitis mimicking advanced gallbladder carcinoma: A case report and review of literature显示文摘Xanthogranulomatous 胆汁(XGC ) 是胆囊的破坏煽动性的疾病,很少包含邻近的机关并且模仿国王先进胆囊癌。诊断在病理学的检查以后仅仅通常是可能的。46 42 岁的女人被指我们包含肝核,正确的肝脑叶,恰好结肠的弯曲,和十二指肠的怀疑的胆囊癌症的中心。刷细胞学获得了由内视镜后退胆管造影术(ERC ) 出现了高级发育异常。病人经历了团的在团体切除术,由正确叶切除术,正确的半结肠切除术,和部分十二指肠的切除术组成。出人意料地揭示的病理学的检查一 XGC.Only,为有邻近的机关的直接参与的 XGC 的扩大外科的切除术的六个案例到目前为止被报导了。在这些情况中,与癌给 XGC 的可能的共存,恶意不能被排除,甚至在细胞学和 intraoperative 冰冻切片调查以后。在结论,由于源于在另外的方面上包围机关的高度好攻击的煽动性的侵略的一个方面和可能的复杂并发症上的胆囊癌的差的预后,它似乎这些案例应该被当作恶性瘤直到不那样证明。临床医生们应该包括 XGC 在之中可能微分在肝核群众诊断。 | Antonino Spinelli Guido Schumacher Andreas Pascher Enrique Lopez-Hanninen Hussain Al-Abadi Christoph Benckert Igor M Sauer Johann Pratschke Ulf P Neumann Sven Jonas Jan M Langrehr Peter Neuhaus | 2006 | World Journal of Gastroenterology2006，12，14： | 13 |
| 2 | Resonance-enhanced multi-octave supercontinuum generation in antiresonant hollow-core fibers显示文摘Ultrafast supercontinuum generation in gas-filled waveguides is an enabling technology for many intriguing applications ranging from attosecond metrology towards biophotonics,with the amount of spectral broadening crucially depending on the pulse dispersion of the propagating mode.In this study,we show that structural resonances in a gas-filled antiresonant hollow core optical fiber provide an additional degree of freedom in dispersion engineering,which enables the generation of more than three octaves of broadband light that ranges from deep UV wavelengths to near infrared.Our observation relies on the introduction of a geometric-induced resonance in the spectral vicinity of the ultrafast pump laser,outperforming gas dispersion and yielding a unique dispersion profile independent of core size,which is highly relevant for scaling input powers.Using a krypton-filled fiber,we observe spectral broadening from 200 nm to 1.7μm at an output energy of B 23μJ within a single optical mode across the entire spectral bandwidth.Simulations show that the frequency generation results from an accelerated fission process of solitonlike waveforms in a non-adiabatic dispersion regime associated with the emission of multiple phase-matched Cherenkov radiations on both sides of the resonance.This effect,along with the dispersion tuning and scaling capabilities of the fiber geometry,enables coherent ultra-broadband and high-energy sources,which range from the UV to the mid‐infrared spectral range. | Rudrakant Sollapur Daniil Kartashov Michael Zürch Andreas Hoffmann Teodora Grigorova Gregor Sauer Alexander Hartung Anka Schwuchow Joerg Bierlich Jens Kobelke Mario Chemnitz Markus A Schmidt Christian Spielmann | 2017 | Light(Science & Applications)2017，6，1： | 2 |
| 3 | Effect of thiol antioxidant on body fat and insulin reactivity显示文摘 | Wulf Hildebrandt Andreas Hamann Holger Krakowski-Roosen Ralf Kinscherf Klaus Dugi Roland Sauer Sabrina Lacher Nuria N?bel Anne Bodens Vassiliki Bellou Lutz Edler Peter Nawroth Wulf Dr?ge | 2004 | Journal of Molecular Medicine2004，，5： | 1 |
| 4 | Donor evaluation, donor risks, donor outcome, and donor quality of life in adult-to-adult living donor liver transplantation显示文摘 | Andreas Pascher Igor M. Sauer Marc Walter Enrique Lopez-Haeninnen Tom Theruvath Antonino Spinelli Ruth Neuhaus Utz Settmacher Andrea R. Mueller Thomas Steinmueller Peter Neuhaus | 2002 | Liver Transplantation2002，，9： | 1 |
| 5 | Endothelial dysfunction contributes to severe COVID-19 in combination with dysregulated lymphocyte responses and cytokine networks显示文摘The systemic processes involved in the manifestation of life・threatening COVID-19 and in disease recovery are still incompletely understood,despite investigations focusing on the dysregulation of immune responses after SARS-CoV-2 infection.To define hallmarks of severe COVID-19 in acute disease(n=58)and in disease recovery in con valesce nt patie nts(n=28)from Han nover Medical School,we used flow cytometry and proteomics data with unsupervised clustering analyses.In our observational study,we combined analyses of immune cells and cytokine/chemokine networks with endothelial activation and injury.ICU patients displayed an altered immune signature with prolonged lymphopenia but the expansion of granulocytes and plasmablasts along with activated and terminally differentiated T and NK cells and high levels of SARS-CoV-2-specific antibodies.The core signature of seven plasma proteins revealed a highly inflammatory microenvironment in addition to endothelial injury in severe COVID-19.Changes within this sign ature were associated with either disease progression or recovery.In summary,our data suggest that besides a strong inflammatory response,severe COVID-19 is driven by endothelial activation and barrier disruption,whereby recovery depends on the regeneration of the endothelial integrity. | Louisa Ruhl Isabell Pink Jenny F.Kiihne Kerstin Beushausen Jana Keil Stella Christoph Andrea Sauer Lennart Boblitz Julius Schmidt Sascha David Hans-Martin Jack Edith Roth Markus Cornberg Thomas F.Schulz Tobias Welte Marius M.Hoper Christine S.Falk | 2022 | Signal Transduction and Targeted Therapy2022，7，1： | 1 |
| 6 | The influence of design aesthetics in usability testing :effects on user performance and perceived usability 显示文摘 | Andreas Sonderegger Juergen Sauer | 2010 | Applied Ergonomics2010，，40： | 1 |
| 7 | The influence of socio-cultural background and product value in usability testing显示文摘 | Andreas Sonderegger Juergen Sauer | 2012 | Applied Ergonomics2012，，： | 1 |
| 8 | Off-label-use of sulfur-hexafluoride in voiding urosonography for diagnosis of vesicoureteral reflux in children:A survey on adverse events显示文摘AIM To evaluate the risk profile of sulfur hexafluoride in voiding urosonography(VUS) based on a large cohort of children.METHODS Since 2011 sulfur hexafluoride(SH,SonoV ue?,Bracco,Italy) is the only ultrasound contrast available in the European Union and its use in children has not been approved.Within a 4-year-period,531 children with suspected or proven vesicoureteral reflux(f/m = 478/53; mean age 4.9 years; 1 mo-25.2 years) following parental informed consent underwent VUS with administration of 2.6 ± 1.2 mL SH in a two-center study.A standardizedtelephone survey on adverse events was conducted three days later.RESULTS No acute adverse reactions were observed.The survey revealed subacute,mostly self-limited adverse events in 4.1%(22/531).The majority of observed adverse events(17/22) was not suspected to be caused by an allergic reaction: Five were related to catheter placement,three to reactivated urinary tract infections,five were associated with perineal disinfection before voiding urosonography or perineal dermatitis and four with a common cold.In five patients(0.9%) hints to a potential allergic cause were noted: Perineal urticaria was reported in three interviews and isolated,mild fever in two.These were minor self-limited adverse events with a subacute onset and no hospital admittance was necessary.Ninety-six point two percent of the parents would prefer future VUS examinations with use of SH.CONCLUSION No severe adverse events were observed and indications of self-limited minor allergic reactions related to intravesical administration of SH were reported in less than 1%. | Alexander Sauer Clemens Wirth Isabel Platzer Henning Neubauer Simon Veldhoen Alexander Dierks Reinhard Kaiser Andreas Kunz Meinrad Beer Thorsten Bley | 2017 | World Journal of Clinical Pediatrics2017，6，1： | 1 |
| 9 | The vanilloid receptor TRPV1 is activated and sensitized by local anesthetics in rodent sensory neurons显示文摘 | Leffler Andreas Fischer Michael J Rehner Dietlinde Kienel Stephanie Kistner Katrin Sauer Susanne K Gavva Narender R Reeh Peter W Nau Carla | 2008 | Journal of Clinical Investigation2008，，： | 1 |
| 10 | Conventional and wavelet coherence applied to sensory-evoked electrical brain activity显示文摘 | Alexander Klein Tomas Sauer Andreas Jedynak | 2004 | IEEE Transactions on Biomedical Engineering2004，，： | 1 |
| 11 | The influence of design aesthetics in usability testing:effects on user performance and perceived usability 显示文摘 | Andreas Sonderegger Juergen Sauer | 2010 | Applied Ergonomics2010，41，3： | 1 |
| 12 | Risk factors for bile leakage after hepatectomy显示文摘In the current issue,Panaro et al^([1])presented a retrospective single-center study on 411 hepatectomies for benign and malignant liver tumors.After exclusion of hilar cholangiocarcinomas and hepatectomies with simultaneous biliary or pancreatic resection,risk factors for postoperative bile leakage were analyzed.Progress | Benjamin Struecker Andreas Andreou Igor M Sauer Johann Pratschke Daniel Seehofer | 2016 | Hepatobiliary & Pancreatic Diseases International2016，15，1： | 0 |
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