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| 1 | Potential forensic application of DNA methylationprofiling to body fluid identification 显示文摘 | HWAN YOUNG LEE MYUNG JIN PARK AJIN CI-IOI | 2012 | Int J Legal Med2012，126，1： | 1 |
| 2 | 4.1N suppresses hypoxia-induced epithelial-mesenchymal transition inepithelial ovarian cancer cells显示文摘 | Letian Zhang Ajin Hu Mengrui Li Hongquan Zhang Caixia Ren Xiuli An Congrong Liu | 2016 | Molecular Medicine Reports2016，，： | 1 |
| 3 | Arabidopsis ESKl encodes a novel regulator of freezing tolerance显示文摘 | Xin Zhanguo Mandaoker Ajin Last Robert L Browse John | | 0，，05： | 1 |
| 4 | Amino acid substitution in α-Helix 7 of Cry1Ac δ-endotoxin of Bacillus thuringiensis leads to enhanced toxicity to Helicoverpa armigera Hubner显示文摘 | ARTI C PARAMITA G AJIN D M | 1999 | Federation of European Microbiological Societies Microbiology Letters1999，458，： | 1 |
| 5 | Label- free protein detection using a microfluidic Coulter- counter device 显示文摘 | Rodriguez -Trujillo R Ajine M A Orzan A | 2014 | Sensors and Actuators B : Chemical2014，190，： | 1 |
| 6 | Transcriptional regulators of stamen development in Arabidopsis identified by transcriptional profiling 显示文摘 | Mandaokar Ajin Thines Bryan Shin Byongehul | 2006 | The Plant Journal2006，46，6： | 1 |
| 7 | CONSTRUCTION OF THE ENCRYPTION MATRIX BASED ON CHEBYSHEV CHAOTIC NEURAL NETWORKS显示文摘The paper proposes a novel algorithm to get the encryption matrix. Firstly, a chaotic sequence generated by Chebyshev chaotic neural networks is converted into a series of low-order integer matrices from which available encryption matrices are selected. Then, a higher order encryption matrix relating real world application is constructed by means of tensor production method based on selected encryption matrices. The results show that the proposed algorithm can produce a 'one-time pad cipher' encryption matrix with high security; and the encryption results have good chaos and auto-correlation with the natural frequency of the plaintext being hidden and homogenized. | Zou Ajin Wu Wei Li Renfa Li Yongjiang | 2012 | Journal of Electronics(China)2012，29，3： | 0 |
| 8 | Loss of 4.1N in epithelial ovarian cancer results in EMT and matrix-detached cell death resistance显示文摘Epithelial ovarian cancer(EOC)is one of the leading causes of death from gynecologic cancers and peritoneal dissemination is the major cause of death in patients with EOC.Although the loss of 4.1N is associated with increased risk of malignancy,its association with EOC remains unclear.To explore the underlying mechanism of the loss of 4.1N in constitutive activation of epithelial-mesenchymal transition(EMT)and matrixdetached cell death resistance,we investigated samples from 268 formalin-fixed EOC tissues and performed various in vitro and in vivo assays.We report that the loss of 4.1N correlated with progress in clinical stage,as well as poor survival in EOC patients.The loss of 4.1N induces EMT in adherent EOC cells and its expression inhibits anoikis resistance and EMT by directly binding and accelerating the degradation of 14-3-3 in suspension EOC cells.Furthermore,the loss of 4.1N could increase the rate of entosis,which aggravates cell death resistance in suspension EOC cells.Moreover,xenograft tumors in nude mice also show that the loss of 4.1N can aggravate peritoneal dissemination of EOC cells.Single-agent and combination therapy with a ROCK inhibitor and a 14-3-3 antagonist can reduce tumor spread to varying degrees.Our results not only define the vital role of 4.1N loss in inducing EMT,anoikis resistance,and entosis-induced cell death resistance in EOC,but also suggest that individual or combined application of 4.1N,14-3-3 antagonists,and entosis inhibitors may be a promising therapeutic approach for the treatment of EOC. | Dandan Wang Letian Zhang Ajin Hu Yuxiang Wang Yan Liu Jing Yang Ningning Du Xiuli An Congying Wu Congrong Liu | 2021 | Protein & Cell2021，12，2： | 0 |
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