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| 1 | The Telephone System as aPublic Good : Static and Dynamic Aspects 显示文摘 | Artie R Averous C | 1973 | Bell Journalof Economics1973,,4: | 1 |
| 2 | 早期乳腺癌最佳辅助化疗方案与人类表皮生长因子受体2阳性乳腺癌辅助靶向治疗选择:依据 ASCO 对 CCO临床实践指南的改编显示文摘目的研究加拿大安大略癌症治疗中心(CCO)关于早期乳腺癌最佳辅助化疗方案,包括人类表皮生长因子受体2(HER2)阳性乳腺癌辅助靶向治疗方案,并对其进行改编。方法按照美国临床肿瘤协会(ASCO)对其他组织临床实践指南改编的策略和程序,对CCO临床实践指南的严谨性与内容适用性进行回顾。结果基于对CCO临床实践指南内容的回顾,ASCO小组认为,CCO临床实践指南在整体上清晰全面,以最确切的科学证据为基础,为患者提供可接受的治疗选项。推荐关于辅助化疗方案的决定,应考虑到基线复发风险、毒性、利益可能性和宿主因素(如合并症)。对于高风险HER2阴性的身体状况良好的人群,蒽环类和紫杉烷治疗方案是标准治疗方案。4个周期的多西他赛和环磷酰胺治疗方案是可接受的非蒽环类治疗方案。对于高风险HER2阳性患者,推荐蒽环类与紫杉烷序贯疗法联合曲妥单抗或多西他赛、卡铂、曲妥单抗进行6个周期的治疗。对于低风险、非淋巴结转移、HER2阳性人群,推荐每周一次的紫杉醇和曲妥单抗连续进行12个周期的替代治疗。曲妥单抗应持续使用1年。不应采用铂复合盐对三阴性人群进行常规的辅助管理,除非出现有效的生存数据加以支持。 | Neelima Denduluri Mark R Somerfield Andrea Eisen Jamie N Holloway Arti Hurria Tari A King Gary H Lyman Ann H Partridge Melinda L Telli Maureen E Trudeau Antonio C Wolff 本刊编辑部 | 2016 | 中国全科医学2016,19,18: | 1 |
| 3 | A rterial calcifications and bone histom orphom etry in endstage renal disease显示文摘 | Longdon GM M arty C Marchais S J | | 0,,: | 1 |
| 4 | SSR markers closely associated with genes for resistance to root-knot nematode on chromosomes 11 and 14 of Upland cotton显示文摘 | Gutiérrez O A Jenkins J N McC arty J C | 2010 | Theoretical and Applied Genetics2010,121,7: | 1 |
| 5 | The effects of long-term sleep deprivation on the long-term potentiation in the dentate gyrus and brain oxidation status in rats显示文摘 | Stier C Dolu N Artis AS | 2011 | Neurosci Res2011,70,1: | 1 |
| 6 | Large-scale forest inventories of the United States and China reveal positive effects of biodiversity on productivity显示文摘Background:With the loss of species worldwide due to anthropogenic factors,especially in forested ecosystems,it has become more urgent than ever to understand the biodiversity-ecosystem functioning relationship(BEFR).BEFR research in forested ecosystems is very limited and thus studies that incorporate greater geographic coverage and structural complexity are needed.Methods:We compiled ground-measured data from approx.one half mil ion forest inventory sample plots across the contiguous United States,Alaska,and northeastern China to map tree species richness,forest stocking,and productivity at a continental scale.Based on these data,we investigated the relationship between forest productivity and tree species diversity,using a multiple regression analysis and a non-parametric approach to account for spatial autocorrelation.Results:In general,forests in the eastern United States consisted of more tree species than any other regions in the country.The highest forest stocking values over the entire study area were concentrated in the western United States and Central Appalachia.Overall,96.4 % of sample plots(477,281)showed a significant positive effect of species richness on site productivity,and only 3.6 %(17,349)had an insignificant or negative effect.Conclusions:The large number of ground-measured plots,as well as the magnitude of geographic scale,rendered overwhelming evidence in support of a positive BEFR.This empirical evidence provides insights to forest management and biological conservation across different types of forested ecosystems.Forest timber productivity may be impaired by the loss of species in forests,and biological conservation,due to its potential benefits on maintaining species richness and productivity,can have profound impacts on the functioning and services of forested ecosystems. | James V Watson Jingjing Liang Patrick C Tobin Xiangdong Lei James S Rentch Catherine E Artis | 2015 | Forest Ecosystems2015,2,4: | 1 |
| 7 | Filebased data processing on Messenger显示文摘 | Krupiarz C J Artis D A Calloway A B | | 0,,8: | 1 |
| 8 | Amino acid substitution in α-Helix 7 of Cry1Ac δ-endotoxin of Bacillus thuringiensis leads to enhanced toxicity to Helicoverpa armigera Hubner显示文摘 | ARTI C PARAMITA G AJIN D M | 1999 | Federation of European Microbiological Societies Microbiology Letters1999,458,: | 1 |
| 9 | The role of IL- 27 in the development of T-cell responses during parasitic infections显示文摘 | Hunter C A Villarino A Artis D | 2004 | Immunol Rev2004,202,: | 1 |
| 10 | Notch signaling is an important regu-lator of type 2 immunity 显示文摘 | Tu L Fang T C Artis D | 2005 | J Exp Med2005,202,8: | 1 |
| 11 | Welcome to the neighborhood:epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites显示文摘 | Saenz S A Taylor B C Artis D | 2008 | Immunol Rev2008,226,: | 1 |
| 12 | The dynamic influence of commensal bacteria on the immune response to pathogens显示文摘 | Michael C Abt David Artis | 2012 | Current Opinion in Microbiology2012,,: | 1 |
| 13 | Welcome to the neighborhood:epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites显示文摘 | Saenz S A Taylor B C Artis D | 2008 | Immunol Rev2008,226,: | 1 |
| 14 | Scaffold- based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent 显示文摘 | ARTIS D R LIN J J ZHANG C | 2009 | Proc Natl Acad Sci USA2009,106,1: | 1 |
| 15 | A rterialcalcificat ions and bone histomo rphometry in end-stage renal disease显示文摘 | London GM M arty C M archais SJ etal | 2004 | J Am Soc Nephrol2004,15,: | 1 |
| 16 | New lessons from old pathogens:what parasitic infections have taught us about the role of nuclear factor-kappaB in the regulation of immunity显示文摘 | MASON N J ARTIS D HUNTER C A | 2004 | Immunol Rev2004,201,1: | 1 |
| 17 | Dendritic cell-intrinsic expression of NF-kappa B1 is required to promote optimal TH2 cell differentiation显示文摘 | Artis D Kane C M Fiore J | 2005 | J Immunol2005,174,11: | 1 |
| 18 | Welcome to the neighborhood:epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites显示文摘 | Saenz S A Taylor B C Artis D | 2008 | Immunol Rev2008,226,: | 1 |
| 19 | Functionality of foamy alveolar macrophages after inhalation of aeroselized liposomal amikacin (arikace) 显示文摘 | Neville ME Liu S Artis C | 2009 | Pediatr Pulm2009,44,32: | 1 |
| 20 | Opposing Roles of NF-kappaB Family Members in the Regulation of NK Cell Proliferation and Production of IFN gamma显示文摘 | Tato C M Mason N Artis D | 2006 | Int Immunol2006,18,4: | 1 |