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| 1 | 含笑属植物所含化学成分与其生物活性的综述(英文)显示文摘属木兰科的含笑属植物大约有80多个种类,它们大都分布在南亚国家。这些植物被当地人用于治疗各种疾病,如发烧、绞痛、麻风病、眼疾、炎症以及解蝎子毒。从9种含笑属植物中分离出94种化合物,例如倍半萜烯、类固醇、黄酮类、阿扑啡类、苯酚、酯类、生物碱和苯环型化合物等,它们具有抗菌、抗癌以及抗疟原虫活性。本文详细地论述了含笑属植物所含化学成分的生物及化学性能。 | Dinesh Kumar Sunil Kumar Seema Taprial Deepak Kashyap Ajay Kumar Om Prakash | 2012 | 中西医结合学报2012，10，12： | 4 |
| 2 | Status and perspectives of hierarchical porous carbon materials in terms of high-performance lithium-sulfur batteries显示文摘Lithium-sulfur(Li-S)batteries,although a promising candidate of next-generation energy storage devices,are hindered by some bottlenecks in their roadmap toward commercialization.The key challenges include solving the issues such as low utilization of active materials,poor cyclic stability,poor rate performance,and unsatisfactory Coulombic efficiency due to the inherent poor electrical and ionic conductivity of sulfur and its discharged products(e.g.,Li2S2 and Li_(2)S),dissolution and migration of polysulfide ions in the electrolyte,unstable solid electrolyte interphase and dendritic growth on an odes,and volume change in both cathodes and anodes.Owing to the high specific surface area,pore volume,low density,good chemical stability,and particularly multimodal pore sizes,hierarchical porous carbon(HPC)mate rials have received considerable attention for circumventing the above pro blems in Li-S batteries.Herein,recent progress made in the synthetic methods and deployment of HPC materials for various components including sulfur cathodes,separators and interlayers,and lithium anodes in Li-S batteries is presented and summarized.More importantly,the correlation between the structures(pore volume,specific surface area,degree of pores,and heteroatom-doping)of HPC and the electrochemical performances of Li-S batteries is elaborated.Finally,a discussion on the challenges and future perspectives associated with HPCs for Li-S batteries is provided. | Yinyu Xiang Liqiang Lu Ajay Giri Prakash Kottapalli Yutao Pei | 2022 | Carbon Energy2022，4，3： | 3 |
| 3 | A Comprehensive Review of Animal Models for Coronaviruses: SARSCoV-2, SARS-CoV, and MERS-CoV显示文摘The recent outbreak of coronavirus disease(COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) has already affected a large population of the world. SARS-CoV-2 belongs to the same family of severe acute respiratory syndrome coronavirus(SARS-CoV) and Middle East respiratory syndrome coronavirus(MERSCoV). COVID-19 has a complex pathology involving severe acute respiratory infection, hyper-immune response, and coagulopathy. At present, there is no therapeutic drug or vaccine approved for the disease. There is an urgent need for an ideal animal model that can reflect clinical symptoms and underlying etiopathogenesis similar to COVID-19 patients which can be further used for evaluation of underlying mechanisms, potential vaccines, and therapeutic strategies. The current review provides a paramount insight into the available animal models of SARS-CoV-2, SARS-CoV, and MERS-CoV for the management of the diseases. | Ashutosh Singh Rahul Soloman Singh Phulen Sarma Gitika Batra Rupa Joshi Hardeep Kaur Amit Raj Sharma Ajay Prakash Bikash Medhi | 2020 | Virologica Sinica2020，35，3： | 3 |
| 4 | Early Enteral Nutrition in Severe Acute Pancreatitis: A Prospective Randomized Controlled Trial Comparing Nasojejunal and Nasogastric Routes显示文摘 | Ajay Kumar Namrata Singh Shyam Prakash Anoop Saraya Yogendra Kumar Joshi | 2006 | Journal of Clinical Gastroenterology2006，，5： | 2 |
| 5 | Single and bundled carbon nanofibers as ultralightweight and flexible piezoresistive sensors显示文摘This work demonstrates the application of electrospun single and bundled carbon nanofibers(CNFs)as piezoresistive sensing elements in flexible and ultralightweight sensors.Material,electrical,and nanomechanical characterizations were conducted on the CNFs to understand the effect of the critical synthesis parameter—the pyrolyzation temperature on the morphological,structural,and electrical properties.The mechanism of conductive path change under the influence of external stress was hypothesized to explain the piezoresistive behavior observed in the CNF bundles.Quasi-static tensile strain characterization of the CNF bundle-based flexible strain sensor showed a linear response with an average gauge factor of 11.14(for tensile strains up to 50%).Furthermore,conductive graphitic domain discontinuity model was invoked to explain the piezoresistivity originating in a single isolated electrospun CNF.Finally,a single piezoresistive CNF was utilized as a sensing element in an NEMS flow sensor to demonstrate air flow sensing in the range of 5-35 m/s. | Debarun Sengupta Ssu-Han Chen Aron Michael Chee Yee Kwok Sean Lim Yutao Pei Ajay Giri Prakash Kottapalli | 2020 | npj Flexible Electronics2020，4，1： | 2 |
| 6 | Silica Induced Early Fibrogenic Reaction in Lung of Mice Ameliorated by Nyctanthes arbortristis Extract显示文摘Objective To investigate the pharmacological effect of Nyctanthes arbortristis (NAT) leaf extract in the prevention of lung injury induced by silica particles. Method Lung injury was induced in Swiss mice through inhalation exposure to silica particles (<5m) using a Flow Past Nose Only Inhalation Chamber at the rate of -10 mg/m3 respirable mass for 5 h. Lung bronchoalveolar lavage (BAL) fluid collected between 48 and 72 h was subjected to protein profiling by electrophoresis and cytokine evaluation by solid phase sandwich ELISA. Lung histopathology was performed to evaluate lung injury. Results Inhalation of silica increased the level of tumor necrosis factor-a (TNF-a), and of the 66 and 63 kDa peptides in the BAL fluid in comparison to sham-treated control. Pre-treatment of silica exposed mice with NAT leaf extract significantly prevented the accumulation of TNF-a in the BAL fluid, but the 66 and 63 kDa peptides remained unchanged. The extract was also effective in the prevention of silica-induced early fibrogenic reactions like congestion, edema and infiltration of nucleated cells in the interstitial alveolar spaces, and thickening of alveolar septa in mouse lung. Conclusion NAT leaf extract helps in bypassing silica induced initial lung injury in mice. | BHOLA NATH PAUL*,1, ANAND PRAKASH*, SIRISH KUMAR*, AJAY K. YADAV*, U. MANI+, ASHOK K. SAXENA*, ANAND PRAKASH SAHU#, KEWAL LAL+, AND KALYAN K. DUTTA+ *Immunobiology Laboratory +Inhalation Toxicology Laboratory #Preventive Toxicology Laboratory Industrial Toxicology Research Centre, M.G.Marg, Lucknow 226001, U.P. India | 2002 | Biomedical and Environmental Sciences2002，15，3： | 1 |
| 7 | Cyclic oxidation behavior of Ni- and Fe-based superalloys in air and Na2SO4-25% NaC1 molten salt environment at 800℃ 显示文摘 | Sidhu T S Ajay Malik Prakash S | 2006 | International Journal of Physical Sciences2006，9，1： | 1 |
| 8 | Lipodystrophy and metabolic complications of highly active antiretroviral therapy显示文摘 | Ankit Parakh Anand Prakash Dubey Ajay Kumar Anshu Maheshwari | 2009 | The Indian Journal of Pediatrics2009，，10： | 1 |
| 9 | Modified synthesis ofnanocomposite,and its application as conversion cathode material in lithium batteries显示文摘 | Raju Prakash Clemens Wall Ajay Kumar | 2011 | Journal of Power Sources2011，196，14： | 1 |
| 10 | Role of vinpocetine in cerebrovascular diseases显示文摘 | Sazal Patyar Ajay Prakash Manish Modi | 2011 | Pharmacological Report2011，63，： | 1 |
| 11 | Cleaning Method: A Validated HPLC method for Determination of Clobetasol Propionate Residues on the Surface of Manufacturing Equipment, International Journal of Analytical and Bioanalytical Chemistry 显示文摘 | Prakash M Ajay V | 2012 | International Journal of Analytical and Bioanalytical Chemistry2012，2，2： | 1 |
| 12 | Production of adventitious shoots and planflets from the hypocotyls explants of Sesbanla rostrata ( Bremek & obrem) 显示文摘 | Ajay Kurnar Jha Surya Prakash Neeru Jain | 2002 | In Vitro Cellular & Developmental Biologe - plant2002，38，5： | 1 |
| 13 | Electrospun bundled carbon nanofibers for skin-inspired tactile sensing,proprioception and gesture tracking applications显示文摘In this work,we report a class of wearable,stitchable,and sensitive carbon nanofiber(CNF)-polydimethylsiloxane(PDMS)composite-based piezoresistive sensors realized by carbonizing electrospun polyacrylonitrile(PAN)nanofibers and subsequently embedding in PDMS elastomeric thin films.Electro-mechanical tactile sensing characterization of the resulting piezoresistive strain sensors revealed a linear response with an average force sensitivity of~1.82 kN−1 for normal forces up to 20 N.The real-time functionality of the CNF-PDMS composite sensors in wearable body sensor networks and advanced bionic skin applications was demonstrated through human motion and gesture monitoring experiments.A skin-inspired artificial soft sensor capable of demonstrating proprioceptive and tactile sensory perception utilizing CNF bundles has been shown.Furthermore,a 16-point pressure-sensitive flexible sensor array mimicking slow adapting low threshold mechanoreceptors of glabrous skin was demonstrated.Such devices in tandem with neuromorphic circuits can potentially recreate the sense of touch in robotic arms and restore somatosensory perception in amputees. | Debarun Sengupta Joshua Romano Ajay Giri Prakash Kottapalli | 2021 | npj Flexible Electronics2021，5，1： | 1 |
| 14 | Survey of inflammatory bowel diseases in India显示文摘 | Govind K. Makharia Balakrishnan S. Ramakrishna Philip Abraham Gourdas Choudhuri Sri Prakash Misra Vineet Ahuja Shobna J. Bhatia Deepak K. Bhasin Sunil Dadhich Gopal K. Dhali Devendra C. Desai Uday C. Ghoshal B. D. Goswami Sanjeev K. Issar Ajay K. Jain Ven | 2012 | Indian Journal of Gastroenterology2012，，6： | 1 |
| 15 | Comparison of Ranson, Glasgow, MOSS, SIRS, BISAP, APACHE-II, CTSI Scores, IL-6, CRP, and Procalcitonin in Predicting Severity, Organ Failure, Pancreatic Necrosis, and Mortality in Acute Pancreatitis显示文摘 | Ajay K. Khanna Susanta Meher Shashi Prakash Satyendra Kumar Tiwary Usha Singh Arvind Srivastava V. K. Dixit Attila Olah | 2013 | HPB Surgery2013，，： | 1 |
| 16 | Assessment of long-term climate variability and its impact on the decadal growth of horticultural crops in central India显示文摘Background:The impact of climate change on horticultural production is of utmost concern worldwide.One such vulnerable region of horticultural importance is the Madhya Pradesh state in the central part of India.It is crucial to analyse the long-term trend in climatic variations and its effect on horticultural crop production.Therefore,this study focuses on detecting trends in mean annual precipitation and temperature of 115 years for the 15 districts covering all the regions of the state as well as projections of all the Representative Concentration Pathway(RCP)climatic scenarios for 2050 and 2080 of Madhya Pradesh state.The decadal(2010–2020)insight into the area and production of horticultural crops is undertaken which will help forecasting the future growth trend.For a better insight,case study on four horticultural crops is undertaken to assess their decadal growth trend vis-à-vis climate parameters in these 15 districts.Results:The Mann–Kendall test for 1901–2016 and Sen’s slope indicated a non-significant change in long-term trend for precipitation except for increasing change in Khargone and decreasing change in Rewa districts.Signifi-cant increasing trend of average temperature is obtained for Hoshangabad,Jabalpur,Sagar and Rewa districts.The Sen’s slope indicated an increase of 0.005 to 0.009℃for maximum temperature and 0.005 to 0.012℃for minimum temperature annually.The projections of all the RCP climate scenarios for the years 2050 and 2080 indicated non-significant variation in precipitation but an increase in maximum(1.4 to 4.1℃)and minimum(1.45 to 4.65℃)annual temperatures.An increasing trend in area and production for horticultural crops is also observed in central India for the study period.There is yield increase in all the crops selected in case study except for potato,which recorded a decreased yield between the years 2010–2015.Conclusion:The Mann–Kendall test and projections indicate towards climate change with a temperature rise.Though the decadal study indicates an increasing trend in horticultural crops,the districts identified to be affected by climate change need to have a plan to lessen the horticultural loss in the state.This study contributes to understand-ing the future climate change trends and its impact on horticultural crop production to formulate various adaptation strategies. | Gaurav Sharma Amita Sharma Nishant Kumar Sinha Om Prakash Sharma Ashutosh Singh Ajai Kumar Pandey Abhishek Kumar Sudhir Kumar Trivedi Bharti Sao Mukesh Kumar Sahu | 2022 | Ecological Processes2022，11，1： | 0 |
| 17 | Is de novo membranous nephropathy suggestive of alloimmunity in renal transplantation?A case report显示文摘BACKGROUND Post-transplant nephrotic syndrome(PTNS)in a renal allograft carries a 48%to 77%risk of graft failure at 5 years if proteinuria persists.PTNS can be due to either recurrence of native renal disease or de novo glomerular disease.Its prognosis depends upon the underlying pathophysiology.We describe a case of post-transplant membranous nephropathy(MN)that developed 3 mo after kidney transplant.The patient was properly evaluated for pathophysiology,which helped in the management of the case.CASE SUMMARY This 22-year-old patient had chronic pyelonephritis.He received a living donor kidney,and human leukocyte antigen-DR(HLA-DR)mismatching was zero.PTNS was discovered at the follow-up visit 3 mo after the transplant.Graft histopathology was suggestive of MN.In the past antibody-mediated rejection(ABMR)might have been misinterpreted as de novo MN due to the lack of technologies available to make an accurate diagnosis.Some researchers have observed that HLA-DR is present on podocytes causing an anti-DR antibody deposition and development of de novo MN.They also reported poor prognosis in their series.Here,we excluded the secondary causes of MN.Immunohistochemistry was suggestive of IgG1 deposits that favoured the diagnosis of de novo MN.The patient responded well to an increase in the dose of tacrolimus and angiotensin converting enzyme inhibitor.CONCLUSION Exposure of hidden antigens on the podocytes in allografts may have led to subepithelial antibody deposition causing de novo MN. | Prakash I Darji Himanshu A Patel Bhavya P Darji Ajay Sharma Ahmed Halaw | 2022 | World Journal of Transplantation2022，12，1： | 0 |
| 18 | Change in quality of life after transcatheter aortic valve implantation and aortic valve replacement surgery in Australian patients aged ≥ 75 years: the effects of EuroSCORE and patient operability显示文摘ObjectiveTo 决定到差别,在在 transcatheter 之间的生活(QOL ) 的通用质量,大动脉的阀门培植(TAVI ) 和病人们由 EuroSCORE 和心队操作性 assessment.MethodsA 解释了的外科的大动脉的阀门代替(AVR ) 与 EuroSCORE > 146 个高风险的病人总计的程度;6 并且年老的 ≥75 年经历了 TAVI (n = 80 ) 或大动脉的阀门代替(n = 66 ) 在 2010 年 2 月和 2013 年 7 月之间。75 个病人的一个总数也完成了外科手术前并且六项月 SF-12 QOL 措施。分析检验了事件主要病态,比较了在调整的组之间的六月 QOL 因为 EuroSCORE 和操作性,和临床上重要的 QOL 改进和 deterioration.ResultsThe AVR 的确定的率组织要求的更长的通风(>24 h )(TAVI 5.0% 对 AVR 20.6% , P = 0.004 ) 并且红血房间的更多的单位[TAVI 0 (0-1 ) 对 AVR 2 (0-3 ) , P = 0.01 ] 。新肾的失败在 TAVI 是更高的(TAVI 5.0% 对 AVR 0% , P = 0.06 ) 。报导的 TAVI 病人显著地降低活力(P = 0.01 ) 由到 AVR 病人的比较,然而,这些调查结果在为操作性的调整以后不再是重要的。在里面两过程,临床上重要的 QOL 改进是普通的[范围25.0%(一般健康)-62.9%(物理角色)]而在 QOL 的恶化不太经常发生了[范围9.3%(物理角色)-33.3%(心理健康)]在 QOL 的 .ConclusionsClinically 重要的改进和恶化在在高风险的六个月是明显的老大动脉的阀门代替病人。一旦操作性被考虑,全面 QOL 没在 TAVI 和 AVR 之间不同。 | Phillip J. Tully Prakash Roshan Greg D Rice Ajay Sinhal Jayme S Bennetts Robert A Baker | 2015 | Journal of Geriatric Cardiology2015，12，1： | 0 |
| 19 | Pharmacognostic evaluation of leaf and root bark of Holoptelea integrifolia Roxb.显示文摘Objective:To evaluate the pharmacognostic characters of an important medicinal plant, Holoptelcu integrifolia(H.integrifolia) Roxb.Methods:The pharmacognostic studies were carried out in terms of organoleptic,microscopic,macroscopic and fluorescence analysis.Results: The characteristic microscopic features of leaves were observed as trichomes,multicellular trichomes,xylem cells,phloem cells,collenchyma,vascular bundles,spongy parenchyma and palisade cells.The characteristic microscopic features of root bark included cork cambium, primary cortex,phloem fibers,medullary rays,endodermis,pericycle and lignified fibers in the transverse section and longitudinal section.The characteristic microscopy of root bark powder showed the presence of cortex cells,sieve tubes,calcium oxalate crystals and lignified fibers. Macroscopic study showed that leaf shape-oval,apex-acute,base-cordate and leaf margin was entire with glabrous surface,bitter taste and characteristic odour.The morphological features of root bark showed deep fissured,rough and firm surface with rhitydome and the periderm parallel to cambium.Conclusions:Various pharmacognostic characters observed in this study help in the identification and standardization of H.integrifolia. | Dinesh Kumar Karunesh Kumar Sunil Kumar Tarun Kumar Ajay Kumar Om Prakash | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，3： | 0 |
| 20 | Helicobacter pylori isolated from gastric juice have higher pathogenic potential than biopsy isolates显示文摘Persistent gastritis induced by Helicobacter pylori(H.pylori)is the strongest known risk factor for gastric cancer(GC).H.pylori is prevalent in about 50%world's population,while it causes cancer in less than 2%of exposed individuals.1 Our studies found that H.pylori infection can induce oncogenic properties in AGS cells by deregulating multiple factors associated with the cell cycle,apoptosis,and other important events associated with cancer progression. | Budhadev Baral Dharmendra Kashyap Nidhi Varshney Tarun Prakash Verma Ajay Kumar Jain Debi Chatterji Vinod Kumar Amit Mishra Awanish Kumar Hem Chandra Jha | 2024 | Genes & Diseases2024，11，1： | 0 |
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