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| 1 | Immune response to an indigenously developed r-Hepatitis B vaccine in mixed population: Study of an accelerated vaccination schedule显示文摘AIM: To establish the safety and efficacy of an indigenously developed r-hepatitis B vaccine using an accelerated schedule and to highlight the social awareness and commitment in preventing the spreading of hepatitis B virus infection.METHODS: The study was a multicentric, double blind,randomized (3:1) study using three doses of vaccine immunization schedule (20 μg for those above 10 years old and 10 μg for those below 10 years old) on d 0, 30and 60. One hundred and sixty-six subjects were enrolled(87 males and 76 females aged 5-35 years). The main outcome measure was assessment of immunogenicity and safety.RESULTS: A 100% seroconversion response was observed on the 30th d after the 1st injection in both the experimental groups. The sero-protection data reported a 41.2-65.6% response on the 30th d after the 1st injection and reached 100% on the 60th d. Descriptive statical analysis showed a geometric mean titer value of 13.77 mIU/mL in the test (BEVAC) group and 10.95 mIU/mL in the commercial control (ENGERIX-B) group on the 30th d after the 1st injection. The response on the 60th d showed a geometric mean titre value (GMT) of 519.84 mIU/mL in the BEVAC group and 475.46 mIU/mL in the ENGERIX-B group. On the 90th d, the antibody titer response was observed to be 2627.58 mIU/mL in the BEVAC group and 2272.72 mIU/mL in the ENGERIX-B group. Two subjects in each group experienced pains at injection site after the first vaccination. A total of six subjects in both groups experienced a solicited adverse reaction, which included pains, swelling and redness at the injection site, three subjects in the group-B had a pain at the injection site after the third dose. No other serious adverse events occurred and no dose-related local or general symptoms were observed during the study.CONCLUSION: The vaccine is safe, efficacious and immunogenic in comparison with the well documented ENGERIX-B. | A Chowdhury A Santra CM Habibullah AA Khan J Karunakaramaiah TSA Kishore AVR Raju S Lahiri | 2005 | World Journal of Gastroenterology2005，11，7： | 12 |
| 2 | 国际胃袖状切除专家共识:基于>12000手术病例的最佳操作指南显示文摘腹腔镜胃袖状切除术(1aparoscopic sleeve gastrectomy,LSG)系相对较新的减重手术方式。因其操作相对简单、治疗肥胖合并疾病及减重效果明显,逐步得以广泛接受。目前美国代谢与减重手术协会将其推荐为肥胖症治疗的单独标准术式。2011年3月25~26日, | 苏远涛 徐安安 朱江帆 Diaz AA Arvidsson D Baker RS Basso N Bellanger D Boza C El Mourad H France M Gagner M Galvao-Neto M Higa KD Himpens J Hutchinson CM Jacobs M Jorgensen JO Jossart G Lakdawala M Nguyen NT Nocca D Prager G Pomp A Ramos AC Rosenthal RJ Shah S Vix M Wittgrove A Zundel N | 2013 | 中国微创外科杂志2013，13，9： | 12 |
| 3 | 血压变异性预测自发性脑出血患者的院内不良预后显示文摘越来越多的证据表明,较高的收缩压变异性(systolicblood pressure variability ,SBPV)可能与脑出血患者的不良预后相关。该研究探讨了 SB PV 与院内脑出血预后之间的关系。研究者在2个医疗系统中收集了10年的自发性脑出血患者的连续数据。记录人口统计学、病史、实验室测试、计算机断层扫描数据、院内治疗情况以及神经和功能评估。在入院后24h内获取血压记录。 | 刘青 叶鹏 Divani AA Liu X Di Napoli M Lattanzi S Ziai W James ML Jafarli A Jafari M Saver JL Hemphill JC Vespa PM Mayer SA Petersen A | 2019 | 中华高血压杂志2019，27，8： | 6 |
| 4 | Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study显示文摘 | Shamir R Mehta Salim Yusuf Ron JG Peters Michel E Bertrand Basil S Lewis Madhu K Natarajan Klas Malmberg Hans-Jürgen Rupprecht Feng Zhao Susan Chrolavicius Ingrid Copland Keith AA Fox | 2001 | The Lancet . 2001 (9281)2001，，9281： | 4 |
| 5 | 妊娠前心血管功能与先兆子痫及胎儿生长受限的关系显示文摘妊娠期间的子痫前期和胎儿生长受限与后期母亲心血管病风险增加有关。目前尚不清楚这种关联是因果关系还是由类似的事先存在的风险因素导致。澄清这种关联需要在受孕前征募研究对象,但在方法上是困难的。 | Foo FL Mahendru AA Masini G Fraser A Cacciatore S MacIntyre DA McEniery CM Wilkinson IB Bennett PR Lees CC 刘青 叶鹏 | 2018 | 中华高血压杂志2018，26，8： | 3 |
| 6 | Analysis of somatostatin receptor subtype mRNA expression in human breast cancer显示文摘 | Evans AA Crook T Laws S | 1997 | BrJ Cancer1997，75，： | 2 |
| 7 | 血压变异性加大与认知功能减退相关显示文摘由于预期寿命增加,越来越多的人将面临与增龄相关的认知困难。因此,确定认知障碍的可改变的风险因素非常重要。极短期到中期的血压变异性(blood pressure variability,BPV)可能就是这样一个因素,因为它可能导致脑缺血。 | Zhou TL Kroon AA van Sloten TT van Boxtel MPJ Verhey FRJ Schram MT Kohler S Stehouwer CDA Henry RMA 刘莉(译) 叶鹏(摘、审校) | 2019 | 中华高血压杂志2019，0，3： | 2 |
| 8 | Water permeability of aquaporin-4 is decreased by protein kinase C and dopamine显示文摘 | Zelenina M Zelenin S Bondar AA | 2002 | Am J Physiol Renal Physiol2002，283，2： | 2 |
| 9 | Why Au and Cu are more selective than Pt for preferential oxidation of CO at low temperature显示文摘 | Kandoi S Gokhale AA Grabow LC | 2004 | Catal Lett2004，93，12： | 2 |
| 10 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 11 | RU486 - induced growth inhibition of human endometrial cells 显示文摘 | Murphy AA Zhou MH Malkapuram S | 2000 | Fertil Steril2000，74，5： | 1 |
| 12 | Coxsackievirus-adenovims receptor (CAR) is essential for early embryonic cardiac development 显示文摘 | Dorner AA Wegmann F Butz S | 2005 | JCellSci2005，118，15： | 1 |
| 13 | Genome-wide RNAi analysis of growth and viability in drosophila cells 显示文摘 | Boutros M Kiger AA Armknecht S | 2004 | Science2004，303，5659： | 1 |
| 14 | Predictive value of Rockall score for rebleeding and mortality in patients with variceal bleeding显示文摘 | Sarwar S Dilshad A Khan AA | 2007 | J Coll Physicians Surg Pak2007，17，5： | 1 |
| 15 | HSP60, Bax, apoptosis and the heart显示文摘 | Gupta S Knowlton AA | 2005 | J Cell Mol Med2005，9，： | 1 |
| 16 | Homocysteine hypothesis for atherothrombotic cardiovascular disease:not validated显示文摘 | Kaul S Zadeh AA Shah PK | 2006 | J Am Coll Cardiol2006，48，5： | 1 |
| 17 | RU486-induced growth inhibition of human endom etrial cells 显示文摘 | Murphy AA Zhou MH Malkapuram S | 2000 | Fertil Steril2000，74，5： | 1 |
| 18 | Treatment by Splenectomy of a Portal Vein Aneurysm in Hepatosplenic Schistosomiasis显示文摘 | Mucenic M Rocha Md Mde S Laudanna AA | 2002 | Rev Inst Med Trop Sao Paulo2002，44，5： | 1 |
| 19 | Assessment of the novel selective aldosterone blocker eplerenone using ambulatory and clinical bloodpressure in patients with systemic hypertension显示文摘 | White WB Carr AA Krause S | 2003 | Am J Cardiol2003，92，1： | 1 |
| 20 | Role of Diffusion-weighted MR Imaging in Cervical Lymphadenophathy显示文摘 | Abdel Razek AA Soliman NY Elkhamary S | 2006 | Eur Radiol2006，16，7： | 1 |
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