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| 1 | New eolian red clay sequence on the western Chinese Loess Plateau linked to onset of Asian desertification about 25 Ma ago显示文摘The expansion of inland Asia deserts has considerably influenced the environmental, social and economic activities in Asia. Aridification of inland Asia, especially timing of the initiation of Asian desertification, is a contentious topic in paleoclimatology. Late Cenozoic eolian loess-red clay sequences on the Chinese Loess Plateau, which possess abundant paleoclimatic and paleo-environmental information, can be regarded as an indicator of inland Asia desertification. Here we present a detailed magnetostratigraphic investigation of a new red clay sequence about 654 m in Zhuanglang located at the western Chinese Loess Plateau. Sedimentological, geochemical, mineralogical, and quartz morphological lines of evidence show that the red clay is of eolian origin. Magnetostratigraphic correlations indicate that this core sequence spans from 25.6 to 4.8 Ma, and typical eolian red clay appears as early as 25 Ma. This extends the lower limit of the red clay on the Chinese Loess Plateau from the previously thought early Miocene back into the late Oligocene. This new red clay record further implies that the inland Asia desertification was initiated at least by the late Oligocene. This sequence provides a unique high-resolution geological record for understanding the inland Asia desertification process since the late Oligocene. | QIANG XiaoKe AN ZhiSheng SONG YouGui CHANG Hong SUN YouBin LIU WeiGuo AO Hong DONG JiBao FU ChaoFeng WU Feng LU FengYan CAI YanJun ZHOU WeiJian CAO JunJi XU XinWen AI Li | 2011 | Science China Earth Sciences2011，54，1： | 73 |
| 2 | Tree-ring precipitation records from Baiyinaobao, Inner Mongolia since A.D. 1838显示文摘Correlation function analysis shows that total precipitation from April to early July (to July 10) in growing season limits the ring width of Picea Koraiensis significantly in Baiyinaobao, Xilinhot, Inner Mongolia. Thus a transfer function is designed to reconstruct the total precipitation from April to early July over the region for the last 160 years. The explained variance of the reconstruction is 49.3% (and 45.7% when adjusted for loss of degrees of freedom, N = 31, r = 0.702, F = 13.608, p < 0.0001). There are three relatively wet periods in the reconstruction which are: 1869—1875, 18861921 and 19431968, and four relatively dry periods: 1851—1868, 1876—1885, 1922—1943 and 1969—1999. Among them, the wet periods of 1886—1921 and 1943—1968, and the dry period of 1922—1943 appeared almost at the same time with those in Mt. Qilian region. Meanwhile, the dry period of 1922—1943 corresponds to high temperature and low rainfall during the 1920s and thereafter, and wetness of 1943—1968 corresponds very well to low temperature and more precipitation after the 1940s in Northwest, Northern China and the Changjiang River drainage basin. Calculation shows that the reconstruction series is significantly correlated with local dry-wet index (r = -0.234, p < 0.007, N = 143). Wavelet analysis indicates that there is a 22-a cycle in the precipitation of April to early July during 18381920, and an 11-a cycle during 1920—1952. No more cycles that reach 95% confidence limits are identified after 1953. The precipitation from April to early July quickly dropped into low during the 1920s. After 1950, precipitation shows a declining trend, but the reconstruction shows a tendency of increase in the late of 1990s. | LIU Yu CAI Qiufang Park Won-Kyu AN Zhisheng MA Limin | 2003 | Chinese Science Bulletin2003，48，11： | 29 |
| 3 | The role of autophagy in cardiac hypertrophy显示文摘Autophagy 从更低的优核质在自然被保存到哺乳动物并且是一重要自我吃, degradative processthat 贡献过剩材料的消除。心脏的肥大被过量 proteinsynthesis,增加的 cardiomyocyte 尺寸,和变厚的室的墙首先描绘并且是支持 arrhythmiaand 心失败的一个主要风险因素。在最近的年里, cardiomyocyte autophagy 被认为在控制 hypertrophicresponse 起一个作用。然而,在心脏的肥大的 cardiomyocyte autophagy 的有益或加重的角色仍然是在心脏的肥大的 cardiomyocyte autophagy 的准确机制进一步要求的 controversial.The 学习。在这评论,我们在心脏的肥大与 autophagy 联系的 summarizethe 争吵并且在心脏的肥大的 thedevelopment 提供卓见进 autophagy 的角色。我们断定未来研究应该强调在 autophagy andthe 之间的关系心脏的肥大的不同阶段,以及 autophagic 流动和选择 autophagy。Autophagy 将是为心脏的肥大的一个 potentialtherapeutic 目标。 | Lanfang Li Jin Xu Lu He Lijun Peng Qiaoqing Zhong Linxi Chen Zhisheng Jiang | 2016 | Acta Biochimica et Biophysica Sinica2016，48，6： | 30 |
| 4 | Carbon isotopic composition of modern soil and paleosol as a response to vegetation change on the Chinese Loess Plateau显示文摘The relationship between the carbon isotopic composition of paleosols and paleovegetation on the Loess Plateau is still unclear. One of the main reasons is that we are short of knowledge about the characteristics of the carbon isotopic composition of modern soil in this area. A preliminary investigation of the carbon isotopic compositions of the modern soil and the loess/paleosol sequence on the Loess Plateau shows that the carbon isotopic composition of modern soil is consistent with the distribution of modern plants on the Loess Plateau, where the ecosystem is dominated by a mixture of C4 and C3 plants. Comparing theδ13C values of modern soil and loess-paleosol sequences from the Xunyi profile, we conclude that C3 plants dominated the landscape during loess sediment stages, while C4 plants expanded during paleosol stages. | LIU Weiguo NING Youfeng AN Zhisheng WU Zhenghai LU Huayu CAO Yunning | 2005 | Science China Earth Sciences2005，48，1： | 24 |
| 5 | Amplitudes, rates, periodicities and causes of temperature variations in the past 2485 years and future trends over the central-eastern Tibetan Plateau显示文摘Amplitudes, rates, periodicities, causes and future trends of temperature variations based on tree rings for the past 2485 years on the central-eastern Tibetan Plateau were analyzed. The results showed that extreme climatic events on the Plateau, such as the Medieval Warm Period, Little Ice Age and 20th Century Warming appeared synchronously with those in other places worldwide. The largest amplitude and rate of temperature change occurred during the Eastern Jin Event (343-425 AD), and not in the late 20th century. There were significant cycles of 1324 a, 800 a, 199 a, 110 a and 2-3 a in the 2485-year temperature series. The 1324 a, 800 a, 199 a and 110 a cycles are associated with solar activity, which greatly affects the Earth surface temperature. The long-term trends (>1000 a) of temperature were controlled by the millennium-scale cycle, and amplitudes were dominated by multi-century cycles. Moreover, cold intervals corresponded to sunspot minimums. The prediction indicated that the temperature will decrease in the future until to 2068 AD and then increase again. | LIU YU CAI QiuFang SONG HuiMing AN ZhiSheng Hans W. LINDERHOLM | 2011 | Chinese Science Bulletin2011，56，28： | 23 |
| 6 | Association-Dissociation of Glycolate Oxidase with Catalase in Rice: A Potential Switch to Modulate Intracellular H2O2 Levels显示文摘在氢过氧化物的快速、动态的变化(H 2 O 2) 层次能用作一个重要信号在植物调整各种各样的生物过程。变化被倾斜在它的生产和清除的率,联系膜的 NADPH oxidases 在被知道起一个关键作用之间的平衡认识到。从 NADPH oxidases 独立地工作, glycolate oxidase (GLO ) 最近为 H 2 O 2 生产在在植物的 gene-for-gene 和非主人抵抗期间。在这研究,我们证明 GLO 身体上在米饭叶子与过氧化氢酶(猫) 交往,并且相互作用能是由水杨酸酸(SA ) 的 deregulated。而且,调停 GLO 的 H 2 O 2 累积被 SA synergistically 提高。在酶建筑群基于底层 channeling 的著名机制,导致 SA 的 H 2 O 2 累积多半源于导致 SA 的 GLO 猫分离。在 GLO 猫复杂、调停 GLO 的 H 2 O 2 生产在 photorespiration 期间很高,而为 H 2 O 2( 测量 K m ≈
43 公里) 是非常地低的。这唯一的联合能进一步加强 H 2 O 2 当 GLO 从猫被分裂时。一起拿,我们建议响应环境应力或刺激, GLO 和猫的物理协会分离似乎用作特定的机制调制 H 2 在米饭的 O 2 层次。 | Zhisheng Zhang Yuanyuan Xu Zongwang Xie Xiangyang Li Zheng-Hui He Xin-Xiang Peng | 2016 | Molecular Plant2016，9，5： | 21 |
| 7 | Pretreated methods on loess-palaeosol samples granulometry显示文摘Twenty representative samples were collected from the Chinese loess plateau and each sample was prepared in 6 different ways respectively in order to test the influences of pretreated methods on grain size measurement. The results show that (ⅰ) different pretreated methods can make a big difference for the samples granulometry; (ⅱ) soaking in distilled water for one day, and then treating with an ultrasonic machine for 10 min can make the sample dispersed. | Huayu Lu Zhisheng An | 1998 | Chinese Science Bulletin1998，43，3： | 20 |
| 8 | Preliminary study on the origin identification of natural gas by the parameters of light hydrocarbon显示文摘The light hydrocarbon composition of 209 natural gas samples and individual light hydrocarbon carbon isotopes of 53 natural gas samples from typical humic-sourced gas and sapropelic-sourced gas in the four basins of China have been determined and analyzed.Some identification parameters for humic-sourced gas and sapropelic-sourced gas are proposed or corrected.The differences of compound-specificδ13C value of individual light hydrocarbon between humic-sourced gas and sapropelic-sourced gas have been founded.The humic-sourced gas has the distribution ofδ13C benzene > -24‰,δ13C toluene >-23‰,δ13C cyclohexane >-24‰andδ13C methyl cyclohexane >-24‰,while the sapropelicsourced gas has the distribution ofδ13C benzene <-24‰,δ13C toluene <-24‰,δ13C cyclohexane <-24‰and δ13C methyl cyclohexane <-24‰.Among the components of C7 light hydrocarbon compound,such as normal heptane(nC7),methyl cyclohexane(MCH)and dimethyl cyclopentane(ΣDMCP),etc,relative contents of nC7 and MCH are influenced mainly by the source organic matter type of natural gas.Therefore,it is suggested that the gas with relative content of nC7 of more than 30%and relative content of MCH of less than 70%is sapropelic-sourced gas,while gas with relative content of nC7 of less than 35%and relative content of MCH of more than 50%is humic-sourced gas.Among components of C5-7 aliphatics, the gas with relative content of C5-7 normal alkane of more than 30%is sapropelic-sourced gas,while the gas with relative content of C5-7 normal alkane of less than 30%is humic-sourced gas.These paremeters have been suggested to identify humic-sourced gas and sapropelic-sourced gas. | HU GuoYi 1,2,3 ,LI Jian 1,2 ,LI Jin 1,2 ,LI ZhiSheng 1,2 ,LUO Xia 1,2 ,SUN QingWu 1,2 &MA ChengHua 1,2 1 Research Institute of Petroleum Exploration and Development(Langfang Branch),Petrochina,Langfang 065007,China 2 The Key Laboratory of Gas Formation and Development,Petrochina,Langfang 065007,China 3 College of Geo-Resources and Information,China University of Petroleum,Beijing 102200,China | 2008 | Science China Earth Sciences2008，51，S1： | 19 |
| 9 | Primary exploration of nonlinear information fusion control theory显示文摘By introducing information fusion techniques into a control field, a new theory of information fusion control (IFC) is proposed. Based on the theory of information fusion estimation, optimal control of nonlinear discrete control system is investigated. All information on control strategy, including ideal control strategy, expected object trajectory and dynamics of system, are regarded as measuring information of control strategy. Therefore, the problem of optimal control is transferred into the one of information fusion estimation. Firstly, the nonlinear information fusion estimation theorems are described. Secondly, an algorithm of nonlinear IFC theory is detailedly deduced. Finally, the simulation results of manipulator shift control are given, which show the feasibility and effectiveness of the presented algorithm. | WANG ZhiSheng WANG DaoBo ZHEN ZiYang | 2007 | Science in China(Series F)2007，50，5： | 18 |
| 10 | The δ^(18)O variation of a stalagmite from Qixing Cave,Guizhou Province and indi-cated climate change during the Holocene显示文摘A stalagmite from Qixing Cave, Guizhou Province was dated with the TIMS U-series method and its oxygen isotope composition was analyzed. On the basis of the ages and the variations of the δ18O of the stalagmite, the climate change of the last 7.7 ka has been reconstructed in this area: 7.7-5.8 ka, summer monsoon maximum period; 5.8-3.8 ka summer monsoon weakening period; 3.8-0.15 ka, weakened summer monsoon and high amplitude climate fluctuations period. We put forward that the increasing trend of δ18O of the stalagmite reflected not only the weakening of the summer monsoon, which was caused by the decreasing of solar radiation in the Northern Hemisphere, but also the possibly decreasing contribution of the southwest monsoon to the rainfall of this area. These results are consistent with the output of the numerical climate-model modeling. The high amplitude fluctuation of the δ18O may imply the quick shift of the contributions of different moisture sources to the precipitation in this area. | CAI Yanjun, ZHANG Meiliang, PENG Zicheng, LIN Yushi, AN Zhisheng, ZHANG Zhaofeng & CAO YunningState Key Laboratory of Loess and Quaternary Geology, Institute of Earth Environment, Chinese Academy of Sciences, Xi’an 710054, China Karst Dynamics Laboratory, Ministry of Land and Resources, Guilin 541003, China Department of Earth and Space Science, University of Science & Technology of China, Hefei 230023, China | 2001 | Chinese Science Bulletin2001，46，22： | 18 |
| 11 | Energy-Optimal and Delay-Bounded Computation Offloading in Mobile Edge Computing with Heterogeneous Clouds显示文摘By Mobile Edge Computing(MEC), computation-intensive tasks are offloaded from mobile devices to cloud servers, and thus the energy consumption of mobile devices can be notably reduced. In this paper, we study task offloading in multi-user MEC systems with heterogeneous clouds, including edge clouds and remote clouds. Tasks are forwarded from mobile devices to edge clouds via wireless channels, and they can be further forwarded to remote clouds via the Internet. Our objective is to minimize the total energy consumption of multiple mobile devices, subject to bounded-delay requirements of tasks. Based on dynamic programming, we propose an algorithm that minimizes the energy consumption, by jointly allocating bandwidth and computational resources to mobile devices. The algorithm is of pseudo-polynomial complexity. To further reduce the complexity, we propose an approximation algorithm with energy discretization, and its total energy consumption is proved to be within a bounded gap from the optimum. Simulation results show that, nearly 82.7% energy of mobile devices can be saved by task offloading compared with mobile device execution. | Tianchu Zhao Sheng Zhou Linqi Song Zhiyuan Jiang Xueying Guo Zhisheng Niu | 2020 | China Communications2020，17，5： | 18 |
| 12 | Discrimination of abiogenic and biogenic alkane gases显示文摘We have combined the analytical data of the carbon isotope distribution pattern, R/Ra and CH4/3He values of abiogenic and biogenic (referring to the thermogenic and bacterial or microbial) alkane gases in China with those of alkane gases from USA, Russia, Germany, Australia and other countries. Four discrimination criteria are derived from this comparative study: 1) Carbon isotopic composition is generally greater than -30‰ for abiogenic methane and less than -30‰ for biogenic methane; 2) Abiogenic alkane gases have a carbon isotopic reversal trend (δ 13C1> δ 13C2> δ 13C3> δ 13C4) with δ 13C1>-30‰ in general; 3) Gases with R/Ra >0.5 and δ 13C11 δ 13C2>0 are of abiogenic origin; 4) Gases (meth- ane) with CH4/3He≤106 are of abiogenic origin, whereas gases with CH4/3He≥1011 are of biogenic origin. | DAI JinXing ZOU CaiNeng ZHANG ShuiChang LI Jian NI YunYan HU GuoYi LUO Xia TAO ShiZhen ZHU GuangYou MI JingKui LI ZhiSheng HU AnPing YANG Chun ZHOU QingHua SHUAI YanHua ZHANG Ying MA ChengHua | 2008 | Science China Earth Sciences2008，51，12： | 17 |
| 13 | An 8.1Ma calcite record of Asian summer monsoon evolution on the Chinese central Loess Plateau显示文摘Carbonates in loess-red clay sequences consist mainly of calcite and dolomite. The EDTA analysis of carbonates in different size fractions and magnetic susceptibility reveal that calcite is a sensitive index of summer monsoon. The chemical analysis of carbonates and calcite from an 8.1 Ma loess-red clay sequence at Chaona on the Chinese central Loess Plateau shows that the evolution of the Asian summer monsoon experienced four stages, namely 8.1―5.5 Ma, 5.5―2.8 Ma, 2.8―1.5 Ma and 1.5―0 Ma, with increasing intensification and fluctuation, suggesting a possible combining impacts of uplift of the Tibetan Plateau and global changes on the Asian summer monsoon. | CHEN XiuLing FANG XiaoMin AN ZhiSheng HAN WenXia WANG Xin BAI Yan HONG Ye | 2007 | Science China Earth Sciences2007，50，3： | 16 |
| 14 | Modern pollen rain in the Lake Qinghai basin, China显示文摘Lake Qinghai is the largest inland brackish lake in China and lies within the NE Tibetan Plateau. Our study shows that pollen assemblages in each vegetation belt are significantly correlated with the vegetation types of this area. Among the herbaceous and shrubby pollen assemblages, Artemisia is over-represented, while Poaceae, Cyperaceae and Polygonaceae are under-represented. Artemisia/ Chenopodiaceae (A/C) ratios with the regional vegetation characteristic can be used as a proper index to reconstruct the history of vegetation and climate in Lake Qinghai basin. Modern pollen in the lake mainly comes from the nearby vegetation, controlled by the directions and velocity of the wind. The distribution of modern pollen in Lake Qinghai tends to be similar in most part of the lake. The difference of pollen sedimentation process in the lake can be potentially influenced by the focusing function of the lake, river streams, and lake current. | SHANG Xue LI XiaoQiang AN ZhiSheng JI Ming ZHANG HongBin | 2009 | Science China Earth Sciences2009，52，10： | 15 |
| 15 | miR-129-5p suppresses proliferation, migration, and induces apoptosis in pancreatic cancer cells by targeting PBX3显示文摘Pancreatic cancer(PC)is the seventh m ost frequent cause of cancer-related deaths world wide with a high mortality.MicroRNAs(miRNAs)act as im portant regulators for the developm ent of PC and participate in the progression of PC.miR-129-5p was reported to regulate the progression of tum ors,such as thyroid cancer and gastric cancer.However,the function of miR-129-5p in PC is still unclear.In this study,the down-regulation of miR-129-5p was detected in PC tissues and PC cells.miR-129-5p was overexpressed or knocked down in AsPC-1 and BxPC-3 cells.The results showed that miR-129-5p overexpression suppressed proliferation,m igration and invasion,and induced apoptosis of PC cells,whereas miR-129-5p knockdown showed opposite effects:In addition,we found that pre-B-cell leukemia hom eobox 3(PBX3)overexpression prom oted proliferation,m igration and invasion,but reduced apoptosis of PC cells.PBX3 was identified as a target of miR-129-5p by inform atics analysis and dual luciferase reporter assay.Finally,our results indicated that miR-129-5p suppressed cell proliferation and m igration by targeting PBX3.This study dem onstrated that miR-129-5p could function as a tu m o r suppressor in the progression and developm ent of PC by targeting PBX3,providing a reliable prognostic factor and a new therapeutic strategy for PC. | Zhisheng Qiu Xiaochun Wang Yuping Shi Mingxu Da | 2019 | Acta Biochimica et Biophysica Sinica2019，51，10： | 15 |
| 16 | High-precision timing of the Quaternary standard samples with thermal ionization mass spectrometry (TIMS) U-series method显示文摘Two national stalagmite standard (GBW04412, GBW04413) and one international coral standard (RKM4) have been determined by using thermal ionization mass spectrometry (TIMS) method. The values of ( 234 U/ 238 U) act , ( 230 Th/ 234 U) act and age are all consistent in error range with the standard values obtained by using α spectrometry. | Peng Zicheng Wang Zhaorong Sun Weidong Ma Zhibang Xia Ming Zhang Chenhui Chen Wenji Zhang Zhonglu An Zhisheng | 1998 | Chinese Science Bulletin1998，43，4： | 14 |
| 17 | Geochemical Characteristics of the Upper Triassic Xujiahe Formation in Sichuan Basin, China and its Significance for Hydrocarbon Accumulation显示文摘The alternative development of coal-bearing hydrocarbon source rocks and low-porosity and low-permeability tight sandstone reservoirs of the Triassic Xujiahe Formation in the Sichuan Basin is favorable for near-source hydrocarbon accumulation. The natural gas composition of the Xujiahe Formation in the Sichuan Basin is dominated by hydrocarbon gases, of which the methane content is80.16%-98.67%. Typically, the C_2^+ content is larger than 5% in main wet gas. The dry gas is mainly distributed in the western and northern regions of the basin. The non-hydrocarbon gases mainly contain nitrogen, carbon dioxide, hydrogen, and helium, with a total content of <2%. The carbon isotope ranges of methane and its homologues in natural gas are: δ^(13)C_1 of-43.8‰ to-29.6‰, δ^(13)C_2 of-35.4‰ to-21.5‰, δ^(13)C_3 of-27.6‰ to-19.8‰,and δ^(13)C_4 of-27.7‰ to-18.8‰. δ^(13)C_3>δ^(13)C_4 occurs in some natural gas with a low evolution degree; such gas is mainly coal-related gas from humic-type source rocks of the Xujiahe Formation. As for the natural gas, δ~2 H_(CH4) values ranged from-195‰ to-161‰,δ~2 H_(C2H6) values ranged from-154‰ to-120‰, and δ~2 H_(C3H8) values ranged from-151‰ to-108‰. The dry coefficient,δ^(13)C and δ~2 H_(CH4) are all positively correlated with the maturity of source rocks. The higher the maturity of source rocks is, the larger the natural gas dry coefficient is and the larger the δ^(13)C and δ~2 H_(CH_4) values are, indicative of the characteristic of near-source accumulation. The δ~2 H_(C2H6) value of natural gas is influenced by paleosalinity to a relatively large extent; the higher the paleosalinity is, the larger the δ~2 H_(C2H6) value is. The Pr/Ph value of the condensate oil ranged from 1.60 to 3.43, illustrating light oxidization-light reduction and partial-oxidization characteristics of the depositional environment of coal-bearing source rocks of the Xujiahe Formation. The natural gas light hydrocarbon(C_5-C_7) from the Xujiahe Formation presented two characteristics: the first was the relatively high aromatic hydrocarbon content(19%-32.1%), which reveals the characteristic of natural gas with humic substances of high-maturity; the second was the low content of aromatic hydrocarbon(0.4%-9.3%),reflecting water-washing during the accumulation of the natural gas. The reported research outcomes indicate a potential mechanism for natural gas accumulation in the Xujiahe Formation, which will further guide natural gas exploration in this region. | XIE Zengye LI Jian LI Zhisheng GUO Jianying LI Jin ZHANG Lu DONG Caiyuan | 2017 | Acta Geologica Sinica(English Edition)2017，91，5： | 14 |
| 18 | Millennial-scale climate change since the last glaciation recorded by grain sizes of loess deposits on the northeastern Tibetan Plateau显示文摘Whether climatic changes in high latitudes of the Northern Hemisphere since the last glaciation have effects on the Tibetan Plateau monsoon, and the variation characteristics of the Plateau monsoon itself are still not solved but of great significance. The 22-m high-resolution Ioess-paleosol sequence in the Hezuo Basin on the northeastern Tibetan Plateau demonstrates that the Plateau winter monsoon experienced a millennial variation similar to high latitude Northern Hemisphere, with cold events clearly correlated with Heinrich events but less for the warm events (Dansgarrd-Oeschger events). It may indicate that the climate system at high latitudes in the Northern Hemisphere had played an important role in both the Plateau monsoon and the high-level westerlies. On 10^4 year scale, there are two distinct anomalous changes, which are not found in the records from high latitude northern hemisphere, revealed by the loess grain size in the Hezuo Basin. One is that there was a considerable grain size increase at -36 kaBP, suggesting an abrupt enhancement of the Plateau winter monsoon at that time; the other is that, during 43--36 kaBP, the grain size decreased distinctly, indicating a notable weakening of the Plateau winter monsoon around that period. Both of the two anomalies suggest that the Tibetan climate may have been controlled by some other factors, besides the high latitude climatic changes in the Northern Hemisphere. | Lü Lianqing FANG Xiaomin LU Huayu HAN Yongxiang YANG Shengli LI Jijun AN Zhisheng | 2004 | Chinese Science Bulletin2004，49，11： | 13 |
| 19 | The effects of redundant control inputs in optimal control显示文摘For a stabilizable system, the extension of the control inputs has no use for stabilizability, but it is important for optimal control. In this paper, a necessary and sufficient condition is presented to strictly decrease the quadratic optimal performance index after control input extensions. A similar result is also provided for H2 optimal control problem. These results show an essential difference between single-input and multi-input control systems. Several examples are taken to illustrate related problems. | DUAN ZhiSheng HUANG Lin YANG Ying | 2009 | Science in China(Series F)2009，52，11： | 13 |
| 20 | Oxidized low-density lipoprotein activates adipophilin through ERK1/2 signal pathway in RAW264.7 cells显示文摘它被报导了那氧化低密度的脂蛋白(Ox-LDL ) 能增加 adipophilin 的表示。然而,详细机制充分没被理解。这研究的目的是在 adipophilin 表示和细胞内部的类脂化合物微滴累积上调查 Ox-LDL 的机制。一个鼠标像巨噬细胞的房间线, RAW264.7,全部被使用,并且 Ox-LDL 以一种剂量依赖者方式导致了 adipophilin 表示,这被发现。而且, Ox-LDL 导致了 peroxisome 激活 proliferator 的受体 --(PPAR ) 表示和 PPAR 特定的禁止者 T0070907 没废除 Ox-LDL-induced adipophilin 表示,而是特定的收缩筋 GW1929。而且, Ox-LDL 导致了 ERK1/2 的 phosphorylation,并且由 PD98059 的 ERK1/2-specific 抑制压制了 Ox-LDL-induced PPAR 和 adipophilin 表示。结果显示出那 ERK1/2 或 PPAR 特定的抑制减少了细胞内部的类脂化合物微滴的数量。同时, PPAR 特定的收缩筋增加了细胞内部的类脂化合物微滴。这些结果建议 Ox-LDL-induced 经由 ERK1/2 激活在 adipophilin 水平增加是在 RAW264.7 房间导致细胞内部的类脂化合物微滴的更大的数量的机制之一,它显示 adipophilin 涉及动脉粥样硬化患者前进。 | Qingnan Liu Zhibing Dai Zhiqiang Liu Xiaohui Liu Chaoke Tang Zuo Wang Guanghui Yi Lushan Liu Zhisheng Jiang Yongzong Yang Zhonghua Yuan | 2010 | Acta Biochimica et Biophysica Sinica2010，42，9： | 13 |
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