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| 1 | Amyloid fibril structure of α-synuclein determined by cryo- electron microscopy显示文摘 | Yaowang Li Chunyu Zhao Feng LUO Zhenying Liu Xinrui Gui Zhipu LUO Xiang Zhang Dan Li Cong Liu Xueming Li | 2018 | Cell Research2018，28，9： | 5 |
| 2 | miR-155 aggravates impaired autophagy of pancreatic acinar cells through targeting Rictor显示文摘The aim of this study was to investigate the role and mechanism of miR-155 in regulating autophagy in a caerulein-induced acute pancreatitis(AP)cellular model.GFP-LC3 immunofluo-rescence assay was performed to detect autophagy vesicle formation in pancreatic acinar cell line AR42J.AR42J cells were transfected with miR-155 mimic,inhibitor,and corresponding controls to explore the effect of miR-155 on autophagy.The protein levels of LC3-I,LC3-11,Beclin-1,and p62 were analyzed by western blot analysis.Dual-luciferase reporter assay was performed to verify the interaction between miR-155 and Rictor(RPTOR independent companion of MTOR complex 2).The results showed that caerulein treatment induced impaired autophagy as evi-denced by an increase in the accumulation of p62 together with LC3-11 in AR42J cells,accompanied by miR-155 upregulation.Furthermore,miR-155 overexpression aggravated,whereas miR-155 silencing reduced the caerulein-induced impairment of autophagy.Mechanistically,Rictor was confirmed to be a direct target of miR-155,which could rescue the miR-155 overexpression-mediated aggravation of im paired autophagy.Collectively,these findings indicate that miR-155 aggravates impaired autophagy in caerulein-treated pancreatic acinar cells by targeting Rictor. | Xueming Zhang Jiangtao Chu Haijun Sun Dali Zhao Biao Ma Dongbo Xue Weihui Zhang Zhituo Li | 2020 | Acta Biochimica et Biophysica Sinica2020，52，2： | 4 |
| 3 | Optimization of a synthetic medium for ethanol production by xylose-fermenting Zymomonas mobilis using response surface methodology显示文摘A synthetic medium for ethanol production by recombinant xylose-fermenting Zymomonas mobilis was optimized using Plackett-Burman(PB) design and response surface methodology(RSM).The effects of 19 medium components were investigated by PB design.Eight of these components were determined to have significant effects on ethanol production.The statistical model was constructed via central composite design(CCD) using five selected variables,including xylose,trisodium citrate,choline chloride,pyridoxine,and thiamine.The validity of the developed model was verified.The ethanol concentration in the optimized medium was 6.7% higher than in the RM medium.The optimized medium was then simplified to give the final synthetic medium(S2),in which the ethanol concentration was 20.7% higher than in the RM medium.Xylose and trisodium citrate were the key medium components influencing ethanol production,while calcium pantothenate was the only growth factor required by recombinant Z.mobilis.Ethanol production and growth response were directly proportional to the logarithm of the concentration of trisodium citrate in the range of 0.1-1.6 g/L. | DONG HuiNa ZHAO XueMing MA YuanYuan ZHANG MinHua | 2012 | Chinese Science Bulletin2012，57，28： | 3 |
| 4 | A high-efficient triboelectric-electromagnetic hybrid nanogenerator for vibration energy harvesting and wireless monitoring显示文摘Scavenging mechanical vibration energy by combining triboelectric nanogenerators(TENGs) and electromagnetic generators(EMGs) is a renewable and low-carbon way to generate electric power. In this paper, we fabricate a cylindrical structure hybrid nanogenerator based on spring structure to effectively scavenge vibration energy. The introduction of spring structure not only enhances the space utilization, but also supports the moving magnet. Owing to its innovative structure, the instantaneous output power of TENG and EMG are 0.88 mW at a load of 10 MΩ and 216.7 mW at a load of 60 Ω, respectively. With the aids of a power management circuit, the hybrid nanogenerator can provide continuous power for two hygrothermographs connected in series. In addition, a self-powered wireless acceleration sensing monitoring system(SWAM) is developed to measure the acceleration signals of vibration sources. This study provides a novel guideline for harvesting mechanical vibration energy. | Jian HE Xueming FAN Dongyang ZHAO Min CUI Bing HAN Xiaojuan HOU Xiujian CHOU | 2022 | Science China(Information Sciences)2022，65，4： | 3 |
| 5 | Spatio-temporal Differentiation of Residential Land for Coastal Town: A Case Study of Dalian Jinshitan显示文摘Based on SPOT5 satellite remote sensing images and land use data in five time phases covering the period 1988–2012, the distribution characteristics, spatial differentiation processes, and driving mechanisms affecting the residential land of the Jinshitan Tourist Resort were studied. The work included a combination of GIS technology, adoption of the differentiation index D, and the multi-group differentiation-measure model D(m). The results provided a basis for the following conclusions: 1) From 1988 to 2012, the degree of differentiation of the rural residential land first decreased, and then increased. The general residential, commercial residential and garden-house land-types all showed declining trends, of which the garden-house type presented the most intense volatility. 2) The overall background of the traditional residential land type was gradually replaced by a new residential land type, and the total area of residential land increased year by year, significantly improving the overall residential conditions. The areas of the new residential land type showed growth, and were increasingly widely distributed in the coastal tourist resorts, transportation corridors, and scenic areas. 3) Government policy, social differentiation, market mechanisms, and individual choices(along with other factors) were mutually promoted, although still restrained. However, all of these factors interacted to constrain the developmental direction and the processes affecting tourism real estate in the Dalian Jinshitan Tourist Resort. | YANG Jun SUN Jing ZHAO Hongdan XI Jianchao LI Xueming | 2016 | Chinese Geographical Science2016，26，4： | 3 |
| 6 | The 2012 Flash Drought Threatened US Midwest Agroecosystems显示文摘In the summer of 2012, the US Midwest, the most productive agricultural region in the world, experienced the most intense and widespread drought on record for the past hundred years. The 2012 drought, characterized as ‘flash drought’, developed in May with a rapid intensification afterwards, and peaked in mid-July. ~76% of crop region and 60% of grassland and pasture regions have been under moderate to severe dry conditions. This study used multiple lines of evidences, i.e., in-situ AmeriFlux measurements, spatial satellite observations, and scaled ecosystem modeling, to provide independent and complementary analysis on the impact of 2012 flash drought on the US Midwest vegetation greenness and photosynthesis carbon uptake. Three datasets consistently showed that 1) phenological activities of all biomes advanced 1–2 weeks earlier in 2012 compared to the other years of 2010–2014;2) the drought had a more severe impact on agroecosystems(crop and grassland) than on forests;3) the growth of crop and grassland was suppressed from June with significant reduction of vegetation index, sun-induced fluorescence(SIF) and gross primary production(GPP), and did not recover until the end of growing season. The modeling results showed that regional total GPP in 2012 was the lowest(1.76 Pg C/yr) during 2010–2014, and decreased by 63 Tg C compared with the other-year mean. Agroecosystems, accounting for 84% of regional GPP assimilation, were the most impacted by 2012 drought with total GPP reduction of 9%, 7%, 6%, and 29% for maize, soybean, cropland, and grassland, respectively. The frequency and severity of droughts have been predicted to increase in future. The results imply the importance to investigate the influences of flash droughts on vegetation productivity and terrestrial carbon cycling. | JIN Cui LUO Xue XIAO Xiangming DONG Jinwei LI Xueming YANG Jun ZHAO Deyu | 2019 | Chinese Geographical Science2019，29，5： | 2 |
| 7 | Collection System of Soil Moisture Information Based on ZigBee and GPRS显示文摘Real-time monitoring and wireless transmission of farmland soil moisture have been paid with more and more attention in the research of agricultural drought monitoring, early warning and prevention and control technology. The hardware design and software design of soil moisture monitoring in farmland were carried out, and a monitoring system based on the principles of ZigBee and GPRS technologies was developed and applied to the actual monitoring of soil moisture in farmland. This study provides a good idea to promote real-time monitoring, wireless transmission and intelligent management of soil moisture in farmland. | Haihong LIU hao JIA Yanhe LIU Qian'ao ZHAO Haoyu WANG Xueming DUAN Zhaoxin ZHANG Jianjie BI | 2019 | Agricultural Biotechnology2019，8，6： | 2 |
| 8 | Silencing myostatin gene by RNAi in sheep embryos显示文摘 | Dayun Tang Huabin Zhu Jianmin Wu Hanzhong Chen Yan Zhang Xueming Zhao Xiaoliang Chen Weihua Du Dong Wang Xiukun Lin | 2012 | Journal of Biotechnology2012，，3： | 2 |
| 9 | Capacitive properties of PANI/MnO 2 synthesized via simultaneous-oxidation route显示文摘 | Jie Zhang Dong Shu Tianren Zhang Hongyu Chen Haimin Zhao Yongsheng Wang Zhenjie Sun Shaoqing Tang Xueming Fang Xiufang Cao | 2012 | Journal of Alloys and Compounds2012，，： | 1 |
| 10 | Starch retrogradation determined by differential thermal analysis (DTA)显示文摘 | Yaoqi Tian Xueming Xu Zhengjun Xie Jianwei Zhao Zhengyu Jin | 2011 | Food Hydrocolloids2011，，6： | 1 |
| 11 | Long-term outcomes of intensity-modulated radiotherapy for 868 patients with nasopharyngeal carcinoma: An analysis of survival and treatment toxicities显示文摘 | Xueming Sun Shengfa Su Chunyan Chen Fei Han Chong Zhao Weiwei Xiao Xiaowu Deng Shaomin Huang Chengguang Lin Taixiang Lu | 2013 | Radiotherapy and Oncology2013，，： | 1 |
| 12 | Identification of differentially expressed proteins between bull X and Y spermatozoa显示文摘 | Xiaoli Chen Huabin Zhu Chengjiang Wu Weidong Han Haisheng Hao Xueming Zhao Weihua Du Tong Qin Yan Liu Dong Wang | 2012 | Journal of Proteomics2012，，： | 1 |
| 13 | Silencing myostatin gene by RNAi in sheep embryos显示文摘 | Dayun Tang Huabin Zhu Jianmin Wu Hanzhong Chen Yan Zhang Xueming Zhao Xiaoliang Chen Weihua Du Dong Wang Xiukun Lin | 2012 | Journal of Biotechnology2012，，3： | 1 |
| 14 | Fatigue and brittle fracture of carbon steel process pipeline显示文摘 | Aiju Li Weiqiang Wang Xueming Wang Dong Zhao | 2004 | Engineering Failure Analysis2004，，4： | 1 |
| 15 | L(+)-lactic acid production by pellet-form Rhizopus oryzae R1021 in a stirred tank fermenter 显示文摘 | Bai Dongmei Jia Minze Zhao xueming | 2003 | Chemical EngineeringScience2003，2358，36： | 1 |
| 16 | A comparative analysis of China and other countries in metabolic engineering: Output, impact and collaboration显示文摘In recent years,metabolic engineering has made great progress in both academic research and industrial applications.However,we have not found any articles that specifically analyze the current state of metabolic engineering in China in comparison with other countries.Here,we review the current development and future trends of global metabolic engineering,conduct an in-depth benchmarking analysis of the development situation of China’s metabolic engineering,and identify current problems as well as future trends.We searched publications in the Scopus database from 2015 to September 2020 in the field of metabolic engineering,and analyzed the output in general,including publication trends,research distribution,popular journals,hot topics and vital institutions,but also analyzed the share of citations,field-weighted citation impact,and production in collaboration with strategic countries in science and technology.This study aims to serve as a reference for later studies,offering a comprehensive view of China’s contribution to metabolic engineering,and as a tool for the elaboration of national public policy in science and technology. | Cong Chen Tao Chen Zhiwen Wang Xueming Zhao | 2021 | Chinese Journal of Chemical Engineering2021，34，2： | 1 |
| 17 | Curing of the Bacillus subtilis Plasmid Using Sodium Dodecyl Sulfate显示文摘 | Lou Kai Ban Kui Zhao Xueming | 2002 | Transactions of Tian jin Univenity2002，8，3： | 1 |
| 18 | Evolutionary engineering of Phaffia rhodozyma for astaxanthin-overproducing strain显示文摘进化工程是宽工程策略为紧张改进由自然进化启发了的新奇 wholegenome。Astaxanthin 广泛地由于它熄灭活跃的氧的能力在化妆品,药品和护理食物被使用了。Phaffia rhodozyma 的紧张改进,为自然 astaxanthin 的主要来源之一,具有为 astaxanthin 的商业兴趣生产。在这研究,一个选择过程为 P 的适应进化被开发。在由内部因素引起的选择压力下面的 rhodozyma 紧张在环境壁龛由添加剂导致了。六个代理人,能在房间导致活跃的氧,分别地被加到文化媒介在进化的过程生产选择压力。起始的紧张, P。rhodozyma AS2-1557,获得起始的紧张人口的 mutagenized,它是然后在选择压力为 550 h 被栽培,文化被转移每 48h。最后,六发展紧张在进化的 150 代以后被选择。发展紧张比起始的紧张生产了多达 48.2% 更多的 astaxanthin。我们的过程可以为 highproduction 紧张的改进提供一种有希望的选择。 | Jixian GONG Nan DUAN Xueming ZHAO | 2012 | Frontiers of Chemical Science and Engineering2012，6，2： | 1 |
| 19 | Preparation and structure of bulk nanostructured WC-Co alloy by high energy ball-milling显示文摘 | Ma Xueming Zhao Ling Ji Gang | 1997 | J Mater Sci Lett1997，16，12： | 1 |
| 20 | Multiplex detection of transgenic maize by microdroplet PCR combined with capillary gel electrophoresis显示文摘With tremendous progress in the commercialization of genetically modified(GM)organisms(GMOs),the safety of GM foods has become a heated topic of debate,and many countries or organizations have adopted the GMO labeling systems[1].GM foods were labeled at 0.9%threshold in the European Union,1%in Brazil,3%in Korea,and 5%in Japan[1,2].In China,all GMOs and GM products are required to be labeled according to the Department of Agriculture,and the main purpose of labeling is to protect consumers’right to know and choose[2]. | Xiao Zhao Qi Zhang Xueming Tang Yan Xu Yanan Du Binan Zhao Xiaori Fan Xiaoxia Zhang Wanjing Zhang Wenjing Wu Kai Zhao | 2019 | Acta Biochimica et Biophysica Sinica2019，51，5： | 1 |
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