|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Relation of atrophic gastritis with Helicobacter pylori-CagA^+ and interleukin-1 gene polymorphisms显示文摘AIM: To determine the association of Helicobacter pylori (H pylori) CagA+ infection and pro-inflammatory poly-morphisms of the genes interleukin (IL)-1RN and IL-1B with the risk of gastric atrophy and peptic ulcers in a dyspeptic population in Costa Rica, a country with high incidence and mortality of gastric cancer. METHODS: Seven biopsy specimens, a fasting blood sample and a questionnaire concerning nutritional and sociodemographic factors were obtained from 501 con-secutive patients who had undergone endoscopy for dyspeptic symptoms. A histopathological diagnosis was made. Pepsinogen concentrations were analyzed by enzyme linked immunosorbent assay (ELISA). Infection with H pylori CagA+ was determined by serology and polymerase chain reaction (PCR). IL-1B and IL-1RN polymorphisms genotyping was performed by PCR-restriction fragment length polymorphism (PCR-RFLP)and PCR respectively. RESULTS: In this dyspeptic population, 86% were H pylori positive and of these, 67.8% were positive for CagA. Atrophic antral gastritis (AAG) was associated with CagA+ status [odd ratio (OR) = 4.1; P < 0.000] and fruit consumption (OR = 0.3; P < 0.00). Atrophic body gastritis (ABG) was associated with pepsinogen PGI/PGII < 3.4 (OR = 4.9; P < 0.04) and alcohol consumption (OR = 7.3; P < 0.02). Duodenal ulcer was associated with CagA+ (OR = 2.9; P < 0.04) and smoking (OR = 2.4; P < 0.04). PGI < 60 μg/L as well as PGI/PGII < 3.4 were associated with CagA+. CONCLUSION: In a dyspeptic population in Costa Rica, H pylori CagA+ is not associated with ABG, but it is a risk factor for AAG. The pro-inflammatory cytokine poly-morphisms IL-1B + 3945 and IL-1RN are not associated with the atrophic lesions of this dyspeptic population. | Rafaela Sierra Clas Une Vanessa Ramírez Warner Alpízar-Alpízar María I González José A Ramírez Antoine de Mascarel Patricia Cuenca Guillermo Pérez-Pérez Francis Mégraud | 2008 | World Journal of Gastroenterology2008，14，42： | 2 |
| 2 | The role of probiotics in aquaculture显示文摘 | José Luis Balcázar Ignacio de Blas Imanol Ruiz-Zarzuela David Cunningham Daniel Vendrell José Luis Múzquiz | 2006 | Veterinary Microbiology2006，，3： | 2 |
| 3 | Uniqueness and boundary behaviour of large solutions to elliptic problems with singular weights显示文摘 | Chuaqui M Cortázar C Elgueta M | 2004 | CPAA2004，3，4： | 1 |
| 4 | GeneXpert polymerase chain reaction for spinal tuberculosis: an accurate and rapid diag- nostic test显示文摘 | Held M Laubscher M Zar H J | 2014 | Bone Joint J2014，96，10： | 1 |
| 5 | Structural and ultrastructural changes on muscle tissue of sea bass,Dicentrarchus labrax L,after cooking and freezing显示文摘 | Ayala M D Albors O L Alcázar A G | 2005 | Aquaculture2005，250，1： | 1 |
| 6 | Metabolomic approach with LC-MS reveals significant effect of pressure on diver’s plasma显示文摘 | Ciborowski M Javier Rupérez F Martínez-Alcázar MP | 2010 | J Proteome Res2010，9，8： | 1 |
| 7 | Food-specific serum IgG4 and lgE titers to common food antigens in irritable bowel syndrome 显示文摘 | Zar S Benson M J KumarD | 2005 | Am J Gastroenterol2005，100，7： | 1 |
| 8 | Food-specific IgG4 antibody-guided exclusion diet improves symptoms and rectal compliance in irritable bowel syndrome显示文摘 | Zar S Mincher L Benson M J | | 0，，07： | 1 |
| 9 | Relationship between microvascular density and expression of vascular endothelial growth factor in p atients with ovarian endometriosis显示文摘 | García-Manero M Santana GT Alcázar JL | 2008 | J Womens Health (Larchmt)2008，17，5： | 1 |
| 10 | Isolation ofVibrio alginolyticus and Vibrio splendidus fromcaptive-bred seahorses with disease symptoms 显示文摘 | Balcázar J L Gallo-Bueno A Planas M | 2010 | Antonie van Leeuwenhoek2010，97，2： | 1 |
| 11 | Psychometric aspects of the W-DEQ:a new questionnaire for the measurement of fear of childbirth显示文摘 | Wijma K Wijma B Zar M | 1998 | Psychosom Obstet Gynaecol1998，19，2： | 1 |
| 12 | Role of food hypersensitivity in irritable bow el syndrome显示文摘 | Zar S Ben son M J Kumar D | 2002 | Minerva Med2002，93，5： | 1 |
| 13 | Food-specific serum IgG4 and IgE titers to common food antigens in irritable bowel syndrome 显示文摘 | Zar S Benson M J Kumar D | 2005 | Am J Gastroenterol2005，100，7： | 1 |
| 14 | Food-specific serum lgG4 and IgE titers to common food antigens in irritable bowel syndrome显示文摘 | Zar S Benson M J Kumar D | 2005 | Am J Gastroenterol2005，100，7： | 1 |
| 15 | Differentiation of cotton-defoliating and nondefoliating pathotypes of Verticillium dahliae by RAPD and specific PCR analyses显示文摘 | Pérez-artés E García-Pedrajas M D Bejarano-Alcàzar J | 2000 | European Journal of Plant Pathology2000，106，： | 1 |
| 16 | Structure,spectroscopic,and magnetic properties of copper(Ⅱ) dinuclear complex with l-hydroxo and l-pyrazolato bridges显示文摘 | Zar B M Drabent K Ciunik Z | 2004 | Inorg Chem Commun2004，7，： | 1 |
| 17 | Evaluation of two different methods for vascular sampling by three-dimensional power Doppler angiography in solid and cystic-solid adnexal masses显示文摘 | Alca'zar JL Prka M | 2009 | Ultrasound Obstet Gynecol2009，33，： | 1 |
| 18 | The Reno-Protective Effect of Hydration With Sodium Bicarbonate Plus N-Acetylcysteine in Patients Undergoing Emergency Percutaneous Coronary Intervention显示文摘 | Alejandro Recio-Mayoral Marinela Chaparro Belén Prado Rocío Cózar Irene Méndez Debasish Banerjee Juan C. Kaski José Cubero Jose M. Cruz | 2007 | Journal of the American College of Cardiology2007，，12： | 1 |
| 19 | Regulation of carotenoid biosynthesis during fruit maturation in the red-fleshed orange mutant Cara Cara显示文摘 | ALQU(E)ZAR B RODRIGO M J ZACAR~AS L | | 0，，10： | 1 |
| 20 | Food - specific serum IgG4 and IgE titers to common food antigens in irritable bowel syndrom 显示文摘 | Zar S Benson M] Kumar D | 2009 | Am J Gastroenterol2009，100，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员