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| 1 | Nutritional Composition and Assessment of Gracilaria lemaneiformis Bory显示文摘化学作文,矿物质元素,维生素,免费的丰满的酸和氨基酸可食的红水藻 Gracilaria lemaneiformis Bory 满足,在 Nan'ao 岛附近的海成年,广东省,在现在的学习被分析。Gracilaria lemaneiformis Bory 显示出 14.65% 的一个全部的糖内容。蛋白质内容是 21% ,哪个约 41% 决心是必要氨基酸(EAA ) 。主要氨基酸部件是 glutamic 酸,白氨酸,精氨酸,和丙氨酸。EAA assayed,蛋氨酸和半胱氨酸看起来与食物和联合国的农业组织提供的 EAA 模式相比是大多数限制氨基酸。全部的类脂化合物内容是 0.87% 并且包括了不饱和的丰满的酸(61%) 的一篇高作文,主要当罂酸的酸和油的酸,和一些多元不堡和总计丰满的酸;十六酸酸是浸透的酸的主要部件(39%) 。维生素 C,碘,磷,和锌相对高级也是在 G 的现在。lemaneiformis。在 G 之间的营养的作文。lemaneiformis 和 Nostoc flagelliforme,广泛地在中国社会被吃的稀罕水藻,被比较。结果建议那 N。flagelliforme 能被用代替由 G。lemaneiformis,不是仅仅因为他们的类似的形状,而且因为他们的近似营养的作文。Gracilaria lemaneiformis 以后可以可能在人的食谱用作潜在的健康食物。 | Xue Wen Changlian Peng Houcheng Zhou Zhifang Lin Guizhu Lin Shaowei Chen Ping Li | 2006 | Journal of Integrative Plant Biology2006，48，9： | 13 |
| 2 | Prescribed Performance Finite-Time Tracking Control for Uncertain Nonlinear Systems显示文摘This work investigates the finite-time tracking control problem for a class of uncertain strict-feedback nonlinear systems from a new perspective. First, a novel concept called finite-time performance function (FTPF) is defined. Further, a new sufficien t condition of finite-time st ability is derived and the tracking error can converge to a predefined region within a finite-time interval. The design process of the proposed technique is simpler. Finally, four simulation examples are carried out to illustrate the effectiveness of presented method. | JING Yuanwei LIU Yang ZHOU Shaowei | 2019 | Journal of Systems Science & Complexity2019，32，3： | 11 |
| 3 | Machine Learning for 5G and Beyond:From ModelBased to Data-Driven Mobile Wireless Networks显示文摘During the past few decades,mobile wireless communications have experienced four generations of technological revolution,namely from 1 G to 4 G,and the deployment of the latest 5 G networks is expected to take place in 2019.One fundamental question is how we can push forward the development of mobile wireless communications while it has become an extremely complex and sophisticated system.We believe that the answer lies in the huge volumes of data produced by the network itself,and machine learning may become a key to exploit such information.In this paper,we elaborate why the conventional model-based paradigm,which has been widely proved useful in pre-5 G networks,can be less efficient or even less practical in the future 5 G and beyond mobile networks.Then,we explain how the data-driven paradigm,using state-of-the-art machine learning techniques,can become a promising solution.At last,we provide a typical use case of the data-driven paradigm,i.e.,proactive load balancing,in which online learning is utilized to adjust cell configurations in advance to avoid burst congestion caused by rapid traffic changes. | Tianyu Wang Shaowei Wang Zhi-Hua Zhou | 2019 | China Communications2019，16，1： | 10 |
| 4 | Enhanced electrocatalytic activity of Co@N-doped carbon nanotubes by ultrasmall defect-rich TiO2 nanoparticles for hydrogen evolution reaction显示文摘尽管有是技术上可能的,切开水产生氢实际上是难实施的,主要因为为氢进化反应的持续、有效的地球丰富的催化剂的缺乏(她的) 。此处,我们报导一持久、高度活跃电气化学她基于充满缺点的 TiO 2 , nanoparticles 在公司做 nanoparticles@N 的碳 nanotubes 上装载了的催化剂(D-TiO 2/Co@NCT) 由静电的旋转和一个随后的锻烧过程综合了。ultrasmall TiO 2 nanoparticles 是在尺寸的 1.5 -2 nm 并且有氧空缺的充满缺点的结构。D-TiO 2/Co@NCT 展览优秀她在酸的电解质的催化活动(0.5 M H 2 那么有 57.5 mV 的一个低发作潜力的 4),( 是的 1 个 mAimmense 潜力由于他们的像三明治的分层的结构的 lithium/ 钠离子电极材料。优化他们的 lithium/sodium-storage 表演,二个问题应该被处理:根本上理解发生在 TMD 电极和发展中的新奇 TMD 的化学反应。在这研究, WSe 2 六角形的 nanoplates 是 sy? | Jiayuan Yu Weijia Zhou Tanli Xiong Aili Wang Shaowei Chen Benli Chu | 2017 | Nano Research2017，10，8： | 7 |
| 5 | Coupled Tamm plasmon polaritons induced narrow bandpass filter with ultra-wide stopband显示文摘Narrow bandpass filters(NBPFs)play important roles in optics,such as quantum communication,spectrometer,and wavelength division multiplexing.However,the stopband and restraint ability of traditional NBPFs is limited.In this article,a coupled Tamm plasmon polaritons(TPPs)induced transmission theory has been proposed to design high-efficiency NBPFs with ultra-wide deep stopbands.An NBPF at 1.55 μm has been experimentally demonstrated with full width at half maximum(FWHM)of 10 nm and stopband ranging from 0.2 to 25 μm which is 62 times wider than that of traditional ones.Furthermore,the restraint depth of the stopband reaches 0.03%,which is only 1/20 of a traditional filter with the same FWHM.Its advantage in restraining ambient light over traditional ones has also been demonstrated with an InGaAs infrared detector.It provides a very powerful way to capture specific narrowband optical signals from ultra-wide strong ambient light,especially useful for daytime quantum communications. | Qingquan Liu Xinchao Zhao Chenlu Li Xinglei Zhou Yu Chen Shaowei Wang Wei Lu | 2022 | Nano Research2022，15，5： | 2 |
| 6 | Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209显示文摘Dear Editor,Coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)and its variants is still a pandemic raging across the world(Supplementary information,Fig.S1a,b).A new variant,Omicron,was first detected in South Africa and got dominant in many regions.1 Omicron has been classified as a variant of concern by the World Health Organization(WHO),whose spike carried more than 30 mutations(Supplementary information,Fig.S1c).1,2 To make a comprehensive evaluation of the susceptibility of Omicron,we summarized plasma samples from 19 convalescent individuals infected with the wild-type(WT)virus,and measured their neutralizing activities against the WT,Beta,Delta,Mu,C.1.2,and Omicron(Supplementary information,Figs.S1d and S2).The Omicron showed more serious resistance to neutralizing antibodies(nAbs)than other variants including Beta and Mu(45.6-fold,9.6-fold,and 15.4-fold,respectively,compared with that against the WT)。 | Bin Ju Qingbing Zheng Huimin Guo Qing Fan Tingting Li Shuo Song Hui Sun Senlin Shen Xinrong Zhou Wenhui Xue Lingyan Cui Bing Zhou Shaowei Li Ningshao Xia Zheng Zhang | 2022 | Cell Research2022，32，5： | 1 |
| 7 | Truncated glycoprotein E of varicella-zoster virus is an ideal immunogen for Escherichia coli-based vaccine design显示文摘Varicella-zoster virus(VZV)is a highly infectious agent responsible for both varicella and herpes zoster disease.Despite high efficacy,there remain safety and accessibility concerns with the licensed vaccines.Here,we sought to produce a VZV g E immunogen using an E.coli expression system.We found that the soluble expression and yield of g E protein could be enhanced via C-terminal truncations to the protein,thereby facilitating a robust and scalable purification process for the purpose of vaccine manufacturing.The lead truncated g E(aa 31–358),hereafter referred to as tg E,was a homogenous monomer in solution and showed excellent antigenicity.Finally,we assessed and compared the immunogenicity of tg E with commercial v Oka LAV and Shingrix vaccine.We found that aluminum-adjuvanted tg E was immunogenic as compared with v Oka LAV.When adjuvanted with AS01B,a two-dose immunization of tg E showed comparable or better potency in antibody responses and cell-mediated immunity with those of the Shingrix vaccine at the same dosage,especially in terms of the proportion of IFN-γ-expressing CD4^(+)T cells.In conclusion,this method of E.coli-mediate tg E expression offers a cost-effective and scalable strategy to generate an ideal VZV g E immunogen for the development of both varicella and zoster vaccines. | Tingting Chen Jie Sun Sibo Zhang Tingting Li Liqin Liu Wenhui Xue Lizhi Zhou Siting Liang Zhili Yu Qingbing Zheng Hai Yu Tong Cheng Jun Zhang Ying Gu Shaowei Li Ningshao Xia | 2023 | Science China(Life Sciences)2023，66，4： | 1 |
| 8 | Resource Allocation for Heterogeneous Cognitive Radio Networks with Imperfect Spectrum Sensing显示文摘 | Wang Shaowei Zhou Zhihua Ge Mengyao | 2013 | IEEE Journal on Selected Areas in Communications2013，31，3： | 1 |
| 9 | Silver nanocubes monolayers as a SERS substrate for quantitative analysis显示文摘Surface-enhanced Raman scattering(SERS)is a powerful spectroscopic tool in quantitative analysis of molecules,where the substrate plays a critical role in determining the detection performance.Herein,a silver nanocubes/polyelectrolyte/gold film sandwich structure was prepared as a reproducible,highperformance SERS substrate by the wate r/oil inte rfacial assembly method.In addition to the hot spots on the nanocubes surface,the edge-to-edge interspace of the Ag nanocubes led to marked enhancement of the SERS intensity,with a limit of detection of 10~(11)mol/L and limit of quantitation of 10~(10)mol/L for crystal violet.When rhodamine 6 G and crystal violet were co-adsorbed on the Ag nanocube surfaces,the characteristic SERS peaks of the two molecules remained well resolved and separated,and the peak intensities varied with the respective concentration,which could be exploited for concurrent detection of dual molecules.Results from this work indicate that organized ensembles of Ag nanocubes can serve as effective SERS substrate can for sensitive analysis for complex molecular systems. | Ziang Zhou Xiuhui Bai Peishen Li Changzheng Wang Ming Guo Yang Zhang Peiren Ding Shaowei Chen Yunyun Wu Qiang Wang | 2021 | Chinese Chemical Letters2021，32，4： | 1 |
| 10 | A homologous and molecular dual-targeted biomimetic nanocarrier for EGFR-related non-small cell lung cancer therapy显示文摘The abnormal activation of epidermal growth factor receptor(EGFR)drives the development of non-small cell lung cancer(NSCLC).The EGFR-targeting tyrosine kinase inhibitor osimertinib is frequently used to clinically treat NSCLC and exhibits marked efficacy in patients with NSCLC who have an EGFR mutation.However,free osimertinib administration exhibits an inadequate response in vivo,with only~3%patients demonstrating a complete clinical response.Consequently,we designed a biomimetic nanoparticle(CMNP^(@Osi))comprising a polymeric nanoparticle core and tumor cell-derived membrane-coated shell that combines membrane-mediated homologous and molecular targeting for targeted drug delivery,thereby supporting a dual-target strategy for enhancing osimertinib efficacy.After intravenous injection,CMNP^(@Osi)accumulates at tumor sites and displays enhanced uptake into cancer cells based on homologous targeting.Osimertinib is subsequently released into the cytoplasm,where it suppresses the phosphorylation of upstream EGFR and the downstream AKT signaling pathway and inhibits the proliferation of NSCLC cells.Thus,this dual-targeting strategy using a biomimetic nanocarrier can enhance molecular-targeted drug delivery and improve clinical efficacy. | Bin Xu Fanjun Zeng Jialong Deng Lintong Yao Shengbo Liu Hengliang Hou Yucheng Huang Hongyuan Zhu Shaowei Wu Qiaxuan Li Weijie Zhan Hongrui Qiu Huili Wang Yundong Li Xianzhu Yang Ziyang Cao Yu Zhang Haiyu Zhou | 2023 | Bioactive Materials2023，，9： | 1 |
| 11 | Resource Allocation for Heterogeneous Cognitive Radio Networks with Imperfect Spectrum Sensing 显示文摘 | Shaowei Wang Zhihua Zhou Mengyao Ge Chonggang Wang | 2013 | Selected Areas in Communications2013，31，3： | 1 |
| 12 | Ion–Electron Coupling Enables Ionic Thermoelectric Material with New Operation Mode and High Energy Density显示文摘Ionic thermoelectrics(i-TE) possesses great potential in powering distributed electronics because it can generate thermopower up to tens of millivolts per Kelvin. However,as ions cannot enter external circuit, the utilization of i-TE is currently based on capacitive charge/discharge, which results in discontinuous working mode and low energy density. Here,we introduce an ion–electron thermoelectric synergistic(IETS)effect by utilizing an ion–electron conductor. Electrons/holes can drift under the electric field generated by thermodiffusion of ions, thus converting the ionic current into electrical current that can pass through the external circuit. Due to the IETS effect, i-TE is able to operate continuously for over 3000 min.Moreover, our i-TE exhibits a thermopower of 32.7 mV K^(-1) and an energy density of 553.9 J m^(-2), which is more than 6.9 times of the highest reported value. Consequently, direct powering of electronics is achieved with i-TE. This work provides a novel strategy for the design of high-performance i-TE materials. | Yongjie He Shaowei Li Rui Chen Xu Liu George Omololu Odunmbaku Wei Fang Xiaoxue Lin Zeping Ou Qianzhi Gou Jiacheng Wang Nabonswende Aida Nadege Ouedraogo Jing Li Meng Li Chen Li Yujie Zheng Shanshan Chen Yongli Zhou Kuan Sun | 2023 | Nano-Micro Letters2023，15，7： | 1 |
| 13 | Oxidation Behavior of Fe-Ni-Co Based Superalloys and Influence of Yttrium Addition显示文摘The oxidation behavior of three Fe-Co-Ni based superalloys with different yttrium additions were investigated at 650°C in air. The oxidation kinetics of the three alloys follows parabolic law initially, then follows linear law. The oxide scale formed on all three alloys consists mainly of Co dissolved Fe3O4 and partly of FeO and Fe2O3, in which Fe3O4 acts as a protective layer. An yttrium addition into the Fe-Co-Ni based superalloys improves their oxidation resistance by reducing the micro-defects in the scales. Thus, the weight gains of the alloys during the oxidation are reduced, and the transition of parabolic law to linear law is postponed. Pegging was observed on the cross section of alloy with 0.08 wt pct yttrium addition after the oxidation. | Jiansheng WU+, Laming ZHANG, Junbiao ZHOU and Yin XU (Open Laboratory for High Temperature Materials and Testing, School of Materials Science and Engineering, Shanghai Jiaotong University, Shanghai 200030, China) Shaowei ZHANG (Beijing Institute of Aerona | 2000 | Journal of Materials Science & Technology2000，16，5： | 0 |
| 14 | MiR-516a-3p is a Novel Mediator of Hepatocellular Carcinoma Oncogenic Activity and Cellular Metabolism显示文摘Hepatocellular carcinoma(HCC)remains one of the most lethal malignancies.We previously demonstrated that the chromosome 19 microRNA cluster(C19MC)was associated with tumor burden and prognosis in patients with HCC.In the current study,we aim to explore the role of miR-516a-3p-an identical mature microRNA(miRNA)co-spliced by four oncogenic pre-miRNAs of C19MC(i.e.,mir-516a-1,mir-516a-2,mir-516b-1,and mir-516b-2)-in HCC.In our cohort of HCC patients,miR-516a-3p was highly expressed in HCC tissues in comparison with adjacent non-tumor tissues.High expression of tumor miR-516a-3p significantly correlated with advanced tumor stages,distinguished high HCC recurrence and mortality,and independently predicted poor prognosis.We further found that miR-516a-3p enhanced the proliferation,migration,and invasiveness of HCC cells in vitro and promoted tumor growth and metastasis in vivo.Among cancer cells,miR-516a-3p could be delivered via exosomes or extracellular vesicles and increased the oncogenic activity of recipient cells.Moreover,we performed comprehensive transcriptomics,proteomics,and metabolomics analysis on the potential mechanism underlying miR-516a-3p-promoted oncogenicity.MixOmic DIABLO analysis showed a close correlation and strong cluster consistency between the proteomics and metabolomics datasets.We further confirmed six proteins(i.e.,LMBR1,CHST9,RBM3,SLC7A6,PTGFRN,and NOL12)as the direct targets of miR-516a-3p and as central players in miR-516a-3p-mediated metabolism regulation.The integrated multi-omics and co-enriched pathway analysis showed that miR-516a-3p regulates the metabolic pathways of HCC cells,particularly purine and pyrimidine metabolism.In conclusion,our findings suggest that miR-516a-3p promotes malignant behaviors in HCC cells by regulating cellular metabolism and affecting neighboring cells via the exosome delivery system.Thus,we suggest miR-516a-3p as a novel molecular target for HCC therapy. | Tao Rui Xueyou Zhang Shi Feng Haitao Huang Shaowei Zhan Haiyang Xie Lin Zhou Shusen Zheng Qi Ling | 2022 | Engineering2022，，9： | 0 |
| 15 | Oligomer-specific single chain variable fragment antibody attenuates memory deficits and brain amyloid burden in Alzheimer disease transgenic mice显示文摘 | Min Zhao Shaowei Wang Yajing Su Weiwei Zhou Xiaolin Yu Ruitian Liu | 2013 | 中国药理通讯2013，30，2： | 0 |
| 16 | Two antibodies show broad,synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD显示文摘Continual evolution of the severe acute respiratory syndrome coronavirus(SARS-CoV-2)virus has allowed for its gradual evasion of neutralizing antibodies(nAbs)produced in response to natural infection or vaccination.The rapid nature of these changes has incited a need for the development of superior broad nAbs(bnAbs)and/or the rational design of an antibody cocktail that can protect against the mutated virus strain.Here,we report two angiotensin-converting enzyme 2 competing nAbs—8H12 and 3E2—with synergistic neutralization but evaded by some Omicron subvariants.Cryo-electron microscopy reveals the two nAbs synergistic neutralizing virus through a rigorous pairing permitted by rearrangement of the 472-489 loop in the receptor-binding domain to avoid steric clashing.Bispecific antibodies based on these two nAbs tremendously extend the neutralizing breadth and restore neutralization against recent variants including currently dominant XBB.1.5.Together,these findings expand our understanding of the potential strategies for the neutralization of SARS-CoV-2 variants toward the design of broad-acting antibody therapeutics and vaccines. | Hui Sun Tingting Deng Yali Zhang Yanling Lin Yanan Jiang Yichao Jiang Yang Huang Shuo Song Lingyan Cui Tingting Li Hualong Xiong Miaolin Lan Liqin Liu Yu Li Qianjiao Fang Kunyu Yu Wenling Jiang Lizhi Zhou Yuqiong Que Tianying Zhang Quan Yuan Tong Cheng Zheng Zhang Hai Yu Jun Zhang Wenxin Luo Shaowei Li Qingbing Zheng Ying Gu Ningshao Xia | 2024 | Protein & Cell2024，15，2： | 0 |
| 17 | Constructing a Scientific and Multidimensional Quality Evaluation Mechanism for Ideological and Political Education in Colleges and Universities显示文摘The construction of curriculum ideological and political education mechanism in colleges and universities in China has begun to take effect.In view of the differences in the key points of different colleges and universities in the construction of curriculum ideological and political education mechanism,the quality evaluation of curriculum ideological and political education mechanism is particularly important.However,the quality evaluation mechanism is related to ability,fairness,and potential.It is essential to assume the effectiveness of moral education in college curriculum ideological and political education as the benchmark,adhere to positioning experts,teachers,and students as the key elements of the main body of the evaluation mechanism,as well as establish a diversified quality evaluation standard system based on the teaching management,infrastructure,and moral education effectiveness.Building a scientific and multi-dimensional quality evaluation mechanism for ideological and political education in colleges and universities would promote the connotative development of ideological and political education in courses. | Jingguan Qin Shaowei Zhou | 2021 | Journal of Contemporary Educational Research2021，5，11： | 0 |
| 18 | A data-driven model of drop size prediction based on artificial neural networks using small-scale data sets显示文摘An artificial neural network(ANN)method is introduced to predict drop size in two kinds of pulsed columns with small-scale data sets.After training,the deviation between calculate and experimental results are 3.8%and 9.3%,respectively.Through ANN model,the influence of interfacial tension and pulsation intensity on the droplet diameter has been developed.Droplet size gradually increases with the increase of interfacial tension,and decreases with the increase of pulse intensity.It can be seen that the accuracy of ANN model in predicting droplet size outside the training set range is reach the same level as the accuracy of correlation obtained based on experiments within this range.For two kinds of columns,the drop size prediction deviations of ANN model are 9.6%and 18.5%and the deviations in correlations are 11%and 15%. | Bo Wang Han Zhou Shan Jing Qiang Zheng Wenjie Lan Shaowei Li | 2024 | Chinese Journal of Chemical Engineering2024，66，2： | 0 |
| 19 | Determining axial dispersion coefficients of pilot-scale annular pulsed disc and doughnut columns显示文摘In this study,a computational fluid dynamics(CFD)method was adopted to calculate axial dispersion coefficients of annular pulsed disc and doughnut columns(APDDCs).Passive tracer was uniformly injected by pulse input at the continuous phase inlet,and its concentration governing equation was solved in liquid–liquidtwo-phase flow fields.The residence time distributions(RTDs)were obtained using the surface monitoring technique.The adopted RTD–CFD method was verified by comparing the axial dispersion coefficient between simulation and experimental results in the literature.However,in pilot-scale APDDCs,the axial dispersion coefficients predicted by the CFD–RTD method were approximately three times larger than experimental results determined by the steady-state concentration profile method.This experimental method was demonstrated to be insensitive to the variation of the axial dispersion coefficient.The CFD–RTD method was more recommended to determine the axial dispersion coefficient.It was found that the axial dispersion coefficient increased with an increase in pulsation intensity,column diameter,and plate spacing,but was little affected by the throughput. | Xiong Yu Han Zhou Qiang Zheng Shan Jing Wenjie Lan Shaowei Li | 2020 | Chinese Journal of Chemical Engineering2020，28，6： | 0 |
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