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| 1 | Epidural Analgesia in the Latent Phase of Labor and the Risk of Cesarean Delivery A Five-year Randomized Controlled Trial显示文摘 | Wang, F. Z. Shen, X. F. Guo, X. R. Peng, Y. Z. Gu, X.Q. | 2009 | 南京医科大学学报(自然科学版)2009，29，11： | 41 |
| 2 | Common Genetic Variants in Pre-MicroRNAs Were Associated With Increased Risk of Breast Cancer in Chinese Women显示文摘 | Hu, Z. B. Liang, J. Wang, Z. W. Tian, T. Zhou, X. Y. Chen, J. P. Miao, R. F. Wang, Y. Wang, X. R. Shen, H. B. | 2009 | 南京医科大学学报(自然科学版)2009，29，4： | 29 |
| 3 | HEAT TRANSFER BEHAVIOR OF SUPERALLOY DROPLETS DURING SPRAY FORMING显示文摘Based on the Newtonian heat transfer formulation and classical heterogeneous nucleation theory, a mathematical model has been established to predict the profile of flight velocity, heat transfer coefficient, temperature, solid fraction and cooling rate of atomizing droplets for a superalloy. The results indicated that above parameters change with different droplet size and flight distance. The changing trend as well as the mechanism for the change are described and discussed. | J.F. Sun, J. Shen, Z. Y. Li, J. Jia and Q.C. Li National Key Laboratory of Metal Precision Hot Processing, Harbin Institute of Technology, Harbin 150001, China | 2000 | Acta Metallurgica Sinica(English Letters)2000，13，2： | 11 |
| 4 | Polymorphisms of MTHFD,plasma homocysteine levels, and risk of gastric cancer in ahigh-risk Chinese population显示文摘Purpose:Accumulative evidence suggests that folate has a protective effect on gastric cancer. The methylenetetrahyd-rofolate dlehydrogenase(MTHFD) plays an important role in folate and homocysteine metabolisms, and polymorphisms of MTHFD may result in disturbance of the folate-mediated homocysteine pathway. The aim of this study is to test the hypothesis that genetic variants of MTHFD and plasma homocysteine levels are associated with risk of gastric cancer and modulated by genotypes of methylenetetrahydrofolate reductase(MTHFR). Experimental Design: We genotyped G1958A and T401C in MTHFD and C677T in MTHFR and detected total plasma homocysteine(tHcy) levels in a case-control study of 589 gastric cancer cases and 635 cancer-free controls in a high-risk Chinese population. Results:The variant genotypes of MTHFD 1958AA and 401CC were associated with a significantly increased risk of gastric canceradjusted odds ratio(OR), 2.05; 95% confidence interval(95% CI),1.34-3.13 for 1958AA; adjusted OR,1.43; 95% CI,1.14-1.80 for 401CC compared with 1958GG/GA and 401TT/TC genotypes, respectively. Both of the effects were more evident in the subjects carrying MTHFR 677CT/TT genotypes. The average tHcy level was significantly higher in gastric cancer cases than in controls(P < 0.01), and the upper quartile of tHcy (> 13.6 mu mol/L) was associated with an 82% significantly increased risk of gastric cancer, compared with the lowest quartile of tHcy(<= 8.0 pmol/L;adjusted OR,1.82; 95% CI,1.20-2.75). Conclusions:The strong associations between MTHFD variants and the plasma tHcy levels and gastric cancer risk suggest, for the first time, a possible gene-environment interaction between genetic variants of folate-metabolizing genes and high tHcy levels in gastric carcinogenesis. | Wang, L. N Ke, Q Chen, W. S Wang, J. M Tan, Y. F Zhou, Y Hua, Z. L Ding, W. L Niu, J. Y Shen, J Zhang, Z. F Wang, X. R Xu, Y. H Shen, H. B Yi Xing | 2007 | 南京医科大学学报(自然科学版)2007，27，7： | 10 |
| 5 | Variant alleles of TGFB1 and TGFBR2 are associated with a decreased risk of gastric cancer in a Chinese population显示文摘 | Jin, G. F. Wang, L. N. Chen, W. S. Hu, Z. B. Zhou, Y. Tan, Y. F. Wang, J. M. Hua, Z. L. Ding, W. L. Shen, J. Zhang, Z. F. Wang, X. R. Xul, Y. C. Shen, H. B. | 2007 | 南京医科大学学报(自然科学版)2007，27，5： | 7 |
| 6 | Variant genotypes and haplotypes of the epidermal growth factor gene promoter are associated with a decreased risk of gastric cancer in a high-risk Chinese population显示文摘 | Jin, G. F. Miao, R. F. Deng, Y. M. Hu, Z. B. Zhou, Y. Tan, Y. F. Wang, J. M. Hua, Z. L. Ding, W. L. Wang, L. Chen, W. S. Shen, J. Wang, X. R. Xu, Y. C. Shen, H. B. | 2007 | 南京医科大学学报(自然科学版)2007，27，10： | 7 |
| 7 | Interfacial bonding mechanism in Al/coated steel dissimilar refill friction stir spot welds显示文摘Defect-free dissimilar Al/zinc coated steel and Al/AlSi coated steel welds were successfully fabricated by refill friction stir spot welding. However, Al alloy and uncoated steel could not be welded under the same welding condition. Al-Zn eutectic layer formed at the Al/zinc coated steel interface showed nonuniformity in thickness and nanoscale intermetallic(IMC) produced was discontinuous. The bonding formation between the Al-Zn layer and the surrounding materials was attributed to a liquid/solid reaction mechanism. Bonding formation at Al alloy and AlSi coated steel interface was attributed to a solid/solid reaction mechanism, as the joining process did not involve with melting of base metals or AlSi coating materials. Kissing bond formed at the weld boundary acted as a crack initiation and propagation site,and the present study showed that weld strength of Al 5754/AlSi coated steel was greatly influenced by properties of original IMC layer. | Z. Shen Y. Ding J. Chen B. Shalch Amirkhiz J.Z. Wen L. Fu A.P. Gerlich | 2019 | Journal of Materials Science & Technology2019，35，6： | 6 |
| 8 | Common non-synonymous polymorphisms in the BRCA1 Associated RING Domain (BARD1) gene are associated with breast cancer susceptibility:a case-control analysis显示文摘The BRCA1 Associated RING Domain(BARD1) gene has been identified as a high penetrance gene for breast cancer, whose germline and somatic mutations were reported in both non-BRCA1/2 hereditary site-specific and sporadic breast cancer cases. BARD1 plays a crucial role in tumor repression, along with its heterodimeric partner BRCA1. In the current study, we tested the hypothesis that common non-synonymous polymorphisms in BARD1 are associated with breast cancer susceptibility in a case-control study of 507 patients with incident breast cancer and 539 frequency-matched cancer-free controls in Chinese women. We genotyped all three common(minor allele frequency (MAF) > 0.10) non-synonymous polymorphisms(Pro24Ser, Arg378Ser, and Val507Met) in BARD1. We found that the BARD1 Pro24Ser variant genotypes(24Pro/Ser and 24Ser/Ser) and Arg378Ser variant homozygote 378Ser/Ser were associated with a significantly decreased breast cancer risk, compared with their wild-type homozygotes, respectively. Furthermore, a significant locus-locus interaction was evident between Pro24Ser and Arg378Ser (P-int = 0.032). Among the 378Ser variant allele carriers, the 24Pro/Pro wild-type homozygote was associated with a significantly increased breast cancer risk (adjusted OR = 1.81, 95% CI = 1.11-2.95), but the subjects having 24Pro/Ser or Ser/Ser variant genotypes had a significantly decreased risk(adjusted OR = 0.74, 95% CI = 0.56-0.99). In stratified analysis, this locus-locus interaction was more evident among subjects without family cancer history, those with positive estrogen receptor (ER) and individuals with negative progesterone receptor(PR). These findings indicate that the potentially functional polymorphisms Pro24Ser and Arg378Ser in BARD1 may jointly contribute to the susceptibility of breast cancer. | Huo, X Hu, Z. B Zhai, X. J Wang, Y Wang, S Wang, X. C Qin, J. W Chen, W. S Jin, G. F Liu, J. Y Gao, J Wei, Q. Y Wang, X. R Shen, H. B | 2007 | 南京医科大学学报(自然科学版)2007，27，7： | 3 |
| 9 | Comparative proteome profile of immature rat ovary during primordial follicle assembly and development显示文摘 | Wang, N. L. Zhang, P. Guo, X. J. Xie, J. Huo, R. Wang, F. Q. Chen, L. Shen, J. Zhou, Z. M. Shi, Q. H. Zhao, B. G. Sha, J. H. | 2009 | 南京医科大学学报(自然科学版)2009，29，11： | 3 |
| 10 | Partitioning and source diagnostics of polycyclic aromatic hydrocarbons in rivers in Tianjin, China显示文摘 | Z. Shi S. Tao B. Pan W.X. Liu W.R. Shen | 2006 | Environmental Pollution2006，，2： | 2 |
| 11 | ZnO Schottky ultraviolet photodetectors显示文摘 | S. Liang H. Sheng Y. Liu Z. Huo Y. Lu H. Shen | 2001 | Journal of Crystal Growth2001，，2： | 2 |
| 12 | Small-scale watershed extended method for non-point source pollution estimation in part of the Three Gorges Reservoir Region显示文摘 | Q. Hong Z. Sun L. Chen R. Liu Z. Shen | 2012 | International Journal of Environmental Science and Technology2012，，4： | 2 |
| 13 | Room temperature excitonic stimulated emission from zinc oxide epilayers grown by plasma-assisted MBE显示文摘 | D.M. Bagnall Y.F. Chen M.Y. Shen Z. Zhu T. Goto T. Yao | 1998 | Journal of Crystal Growth1998，，： | 2 |
| 14 | Genetic diversity and differentiation of indica and japonica rice detected by RFLP analysis显示文摘 | Qifa Zhang M. A. Saghai Maroof T. Y. Lu B. Z. Shen | 1992 | Theoretical and Applied Genetics1992，，4： | 2 |
| 15 | Multi-electron transitions in -Ne and -Ne collisions显示文摘 | X. Cai X. Chen Z. Liu Z. Shen D. Yu S. Wang X. Ma | 1999 | The European Physical Journal D1999，，1： | 1 |
| 16 | Characterization and Temporal Variation of Asian Dust Aerosol from a Site in the Northern Chinese Deserts显示文摘 | X. Y. Zhang S. L. Gong R. Arimoto Z. X. Shen F. M. Mei D. Wang Y. Cheng | 2003 | Journal of Atmospheric Chemistry2003，，3： | 1 |
| 17 | A Quaternion-based Geodetic Datum Transformation Algorithm显示文摘 | Y. -Z. Shen Y. Chen D. -H. Zheng | 2006 | Journal of Geodesy2006，，5： | 1 |
| 18 | The Double Star mission显示文摘 | Liu Z. X. Escoubet C. P Pu Z. Laakso H. Shi J. K. Shen C. Hapgood M | 2005 | Annales Geophysicae2005，，163： | 1 |
| 19 | Comparative mapping of QTLs for agronomic traits of rice across environments using a doubled haploid population显示文摘 | C. Lu L. Shen Z. Tan Y. Xu P. He Y. Chen L. Zhu | 1996 | Theoretical and Applied Genetics1996，，8： | 1 |
| 20 | Iterative inversion of global magnetospheric ion distributions using energetic neutral atom (ENA) images recorded by the NUADU/TC2 instrument显示文摘 | Lu L. McKenna-Lawlor S. Barabash S. Kudela K. Balaz J. Strharsky I. Liu Z. X. Shen C. Cao J. B. Brandt P. C. Tang C. L. Dandouras I | 2008 | Annales Geophysicae2008，，203： | 1 |
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