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| 1 | Laparoscopic appendectomy for acute appendicitis: How to discourage surgeons using inadequate therapy显示文摘Acute appendicitis(AA) develops in a progressive and irreversible manner, even if the clinical course of AA can be temporarily modified by intentional medications. Reliable and real-time diagnosis of AA can be made based on findings of the white blood cell count and enhanced computed tomography. Emergent laparoscopic appendectomy(LA) is considered as the first therapeutic choice for AA. Interval/delayed appendectomy at 6-12 wk after disease onset is considered as unsafe with a high recurrent rate during the waiting time. However, this technique may have some advantages for avoiding unnecessary extended resection in patients with an appendiceal mass. Nonoperative management of AA may be tolerated only in children. Postoperative complications increase according to the patient's factors, and temporal avoidance of emergent general anesthesia may be beneficial for high-risk patients. The surgeon's skill and cooperation of the hospital are important for successful LA. Delaying appendectomy for less than 24 h from diagnosis is safe. Additionally, a semi-elective manner(i.e., LA within 24 h after onset of symptoms) may be paradoxically acceptable, according to the factors of the patient, physician, and institution. Prompt LA is mandatory for AA. Fortunately, the Japanese government uses a universal health insurance system, which covers LA. | tomohide hori takafumi machimoto yoshio kadokawa toshiyuki hata tatsuo ito shigeru kato daiki yasukawa yuki aisu yusuke kimura maho sasaki yuichi takamatsu taku kitano shigeo hisamori tsunehiro yoshimura | 2017 | World Journal of Gastroenterology2017，23，32： | 18 |
| 2 | Retroperitoneal fibrosis associated with immunoglobulin G4-related disease显示文摘Retroperitoneal fibrosis is a rare disease characterized by the development of inflammation and fibrosis in the soft tissues of the retroperitoneum and other abdominal organs.Retroperitoneal fibrosis can be of 2 types:idiopathic and secondary.The recently advocated concept and diagnostic criteria of immunoglobulin G4(IgG4)-related disease,derived from research on autoimmune pancreatitis(AIP),has led to widespread recognition of retroperitoneal fibrosis as a condition caused by IgG4-related disease.We now know that previously diagnosed idiopathic retroperitoneal fibrosis includes IgG4-related disease;however,the actual prevalence is unclear.Conversely,some reports on AIP suggest that retroperitoneal fibrosis is concurrently found in about 10% of IgG4-related disease.Because retroperitoneal fibrosis has no specific symptoms,diagnosis is primarily based on diagnostic imaging(computed tomography and magnetic resonance imaging),which is also useful in evaluating the effect of therapy.Idiopathic retroperitoneal fibrosis can occur at different times with other lesions of IgG4-related disease including AIP.Thus,the IgG4 assay is recommended to diagnose idiopathic retroperitoneal fibrosis.High serum IgG4 levels should be treated and monitored as a symptom of IgG4-related disease.The first line of treatment for retroperitoneal fibrosis is steroid therapy regardless of its cause.For patients with concurrent AIP,i.e.,IgG4-related retroperitoneal fibrosis,the starting dose of steroid is usually 30-40 mg/d.The response to steroid therapy is generally favorable.In most cases,the pancreatic lesion and retroperitoneal fibrosis improve after the initial treatment.However,the epidemiology,treatment for recurring retroperitoneal fibrosis,and long-term prognosis are still largely unknown.Further analysis of such cases and research are necessary. | Nao Fujimori Tetsuhide Ito Hisato Igarashi Takamasa Oono Taichi Nakamura Yusuke Niina Masayuki Hijioka Lingaku Lee Masahiko Uchida Ryoichi Takayanagi | 2013 | World Journal of Gastroenterology2013，19，1： | 14 |
| 3 | Endoscopic approach through the minor papilla for the management of pancreatic diseases显示文摘AIM:To clarify the efficacy and safety of an endoscopic approach through the minor papilla for the management of pancreatic diseases.METHODS:This study included 44 endoscopic retrograde cholangiopancreatography(ERCP) procedures performed in 34 patients using a minor papilla approach between April 2007 and March 2012.We retrospectively evaluated the clinical profiles of the patients,the endoscopic interventions,short-term outcomes,and complications.RESULTS:Of 44 ERCPs,26 were diagnostic ERCP,and 18 were therapeutic ERCP.The most common cause of difficult access to the main pancreatic duct through the major papilla was pancreas divisum followed by distortion of Wirsung's duct.The overall success rate of minor papilla cannulation was 80%(35/44),which was significantly improved by wire-guided cannulation(P = 0.04).Endoscopic minor papillotomy(EMP) was performed in 17 of 34 patients(50%) using a needle-knife(13/17) or a pull-type papillotome(4/17).EMP with pancreatic stent placement,which was the main therapeutic option for patients with chronic pancreatitis,recurrent acute pancreatitis,and pancreatic pseudocyst,resulted in short-term clinical improvement in 83% of patients.Mild post-ERCP pancreatitis occurred as an early complication in 2 cases(4.5%).CONCLUSION:The endoscopic minor papilla approach is technically feasible,safe,and effective when the procedure is performed in a high-volume referral center by experienced endoscopists. | Nao Fujimori Hisato Igarashi Akira Asou Ken Kawabe Lingaku Lee Takamasa Oono Taichi Nakamura Yusuke Niina Masayuki Hijioka Masahiko Uchida Kazuhiro Kotoh Kazuhiko Nakamura Tetsuhide Ito Ryoichi Takayanagi | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，3： | 6 |
| 4 | Serum Mac-2 binding protein is a novel biomarker for chronic pancreatitis显示文摘AIM: To determine the efficacy of Mac-2 binding protein(Mac-2bp) for diagnosis of chronic pancreatitis.METHODS: Fifty-nine healthy volunteers(HV), 162 patients with chronic pancreatitis(CP), and 94 patients with pancreatic ductal adenocarcinoma(PDAC) were enrolled in this study. We measured serum Mac-2bp using our developed enzyme-linked immunosorbent assay kit. Additional biochemical variables were measured using an automated analyzer(including aminotransferase, alanine aminotransferase, γ-glutamyltransferase, alkaline phosphatase, triglyceride, C-reactive protein, and amylase levels) or chemiluminescent enzyme immunoassay(carbohydrate antigen 19-9 and carcinoembryonic antigen). The ability of Mac-2bp to predict CP diagnosis accurately was assessed using receiver operating characteristic(ROC) analyses.RESULTS: Serum Mac-2bp levels were significantly increased in CP patients compared to HV(P < 0.0001) and PDAC patients(P < 0.0001). Area under the ROC curve values of Mac-2bp for the discrimination of CP from HV and PDAC were 0.727 and 0.784, respectively. Multivariate analyses demonstrated that serum Mac-2bp levels were independent determinants for CP diagnosis from HV and PDAC patients. Immunohistological staining showed that Mac-2bp was expressed faintly in the pancreas tissues of both CP and PDAC patients. Serum aspartate aminotransferase, alanine aminotransferase, γ-glutamyltransferase, alkaline phosphatase, and triglyceride levels were significantly higher in patients with CP or PDAC. Serum Mac-2bp levels were highly correlated with protein levels of alanine aminotransferase, γ-glutamyltransferase, and C-reactive protein, but not amylase, suggesting that the damaged liver produces Mac-2bp. CONCLUSION: Measurement of serum Mac-2bp may be a novel and useful biomarker for CP diagnosis as well as liver fibrosis in the general population. | Tomohiro Maekawa Yoshihiro Kamada Yusuke Ebisutani Makiko Ueda Tomoki Hata Koichi Kawamoto Shinji Takamatsu Kayo Mizutani Mayuka Shimomura Tomoaki Sobajima Hironobu Fujii Kotarosumitomo Nakayama Kimihiro Nishino Makoto Yamada Takashi Kumada Toshifumi Ito Hidetoshi Eguchi Hiroaki Nagano Eiji Miyoshi | 2016 | World Journal of Gastroenterology2016，22，17： | 3 |
| 5 | Major hepatectomy using the glissonean approach in cases of right umbilical portion显示文摘Right umbilical portion(RUP) is a rare congenital anomaly associated with anomalous ramifications of the hepatic vessels and biliary system. As such, major hepatectomy requires a careful approach. We describe the usefulness of the Glissonean approach in two patients with vessel anomalies, such as RUP. The first patient underwent a right anterior sectionectomy for intrahepatic cholangiocarcinoma. We encircled several Glissonean pedicles that entered the right anterior section along the right side of the RUP. We temporarily clamped each pedicle, confirmed the demarcation area, and finally cut them. The operation was performed safely and was successful. The second patient underwent a left trisectionectomy for perihilar cholangiocarcinoma. We secured the right posterior Glissonean pedicle. The vessels in the pedicle were preserved, and the other vessels and contents were resected. Identifying the vessels for preservation facilitated the safe lymphadenectomy and dissection of the vessels to be resected. We successfully performed the operation. | Yusuke Ome Kazuyuki Kawamoto Tae Bum Park Tadashi Ito | 2016 | World Journal of Hepatology2016，8，34： | 2 |
| 6 | Excitation Mechanism of Surface Plasmon Polaritons for Surface Plasmon Sensor With 1D Metal Grating Structure for High Refractive Index Medium显示文摘The excitation mechanism of surface plasmon polaritons(SPPs)in a surface plasmon sensor with a one-dimensional(1D)Au diffraction grating on a glass substrate is studied herein.The sensitivity of the sensor for application to a refractometer is also characterized.The SPPs are excited at the following two types of interface:one between the Au grating and the glass substrate and the other between the Au grating and the medium.The simulation data for the transmittance spectra and the transmittance mapping are consistent With the experimental data even when the refractive index of the solution medium is 1.700.Therefore,the excitation mechanism of the SPPs in a surface plasmon sensor is capable of detecting the medium(n=1.700),in which the sensor is used and clarified. | Atsushi MOTOGAITO Yusuke ITO | 2019 | Photonic Sensors2019，9，1： | 2 |
| 7 | Late-onset severe biliary bleeding after endoscopic pigtail plastic stent insertion显示文摘Here, we report our experience with a case of severe biliary bleeding due to a hepatic arterial pseudoaneurysm that had developed 1 year after endoscopic biliary plastic stent insertion. The patient, a 78-year-old woman, presented with hematemesis and obstructive jaundice. Ruptured hepatic arterial pseudoaneurysm was diagnosed, which was suspected to have been caused by long-term placement of an endoscopic retrograde biliary drainage(ERBD) stent. This episode of biliary bleeding was successfully treated by transarterial embolization(TAE). Pseudoaneurysm leading to hemobilia is a rare but potentially fatal complication in patients with long-term placement of ERBD. TAE is a minimally invasive procedure that offers effective treatment for biliary bleeding. | Muneji Yasuda Hideki Sato Yuki Koyama Tomoki Sakakida Takumi Kawakami Takeshi Nishimura Hideki Fujii Yoshikazu Nakatsugawa Shinya Yamada Naoya Tomatsuri Yusuke Okuyama Hiroyuki Kimura Takaaki Ito Hiroyuki Morishita Norimasa Yoshida | 2017 | World Journal of Gastroenterology2017，23，4： | 2 |
| 8 | Comprehensive analysis of rice DREB2-type genes that encode transcription factors involved in the expression of abiotic stress-responsive genes显示文摘 | Satoko Matsukura Junya Mizoi Takumi Yoshida Daisuke Todaka Yusuke Ito Kyonoshin Maruyama Kazuo Shinozaki Kazuko Yamaguchi-Shinozaki | 2010 | Molecular Genetics and Genomics2010，，2： | 1 |
| 9 | Influence of learning curve on short-term results after laparoscopic resection for rectal cancer显示文摘 | Masaaki Ito Masanori Sugito Akihiro Kobayashi Yusuke Nishizawa Yoshiyuki Tsunoda Norio Saito | 2009 | Surgical Endoscopy2009，，2： | 1 |
| 10 | Short-term outcomes of laparoscopic intersphincteric resection from a phase II trial to evaluate laparoscopic surgery for stage 0/I rectal cancer: Japan Society of Laparoscopic Colorectal Surgery Lap RC显示文摘 | Shoichi Fujii Seiichiro Yamamoto Masaaki Ito Shigeki Yamaguchi Kazuhiro Sakamoto Yusuke Kinugasa Yukihito Kokuba Junji Okuda Kenichi Yoshimura Masahiko Watanabe | 2012 | Surgical Endoscopy2012，，11： | 1 |
| 11 | Comprehensive analysis of rice DREB2-type genes that encode transcription factors involved in the expression of abiotic stress-responsive genes显示文摘 | Satoko Matsukura Junya Mizoi Takumi Yoshida Daisuke Todaka Yusuke Ito Kyonoshin Maruyama Kazuo Shinozaki Kazuko Yamaguchi-Shinozaki | 2010 | Molecular Genetics and Genomics2010，，2： | 1 |
| 12 | OsDREB genes in rice, Oryza sativa L, encode transcription activators that function in grought - , high salt - , and cold - responsive gene expression显示文摘 | Dubouzet J G Yoh Sakuma Yusuke Ito | 2003 | Plant J2003，33，： | 1 |
| 13 | Pulmonary resection with chest wall removal and reconstruction for invasive pulmonary mucormycosis during antileukemia chemotherapy显示文摘 | Katsuyuki Asai MD Kazuya Suzuki MD Tsuyoshi Takahashi MD Yasushi Ito MD Teruhisa Kazui MD Yusuke Kita MD | 2003 | The Japanese Journal of Thoracic and Cardiovascular Surgery2003，，4： | 1 |
| 14 | Long-term Outcomes after Intersphincteric Resection for Low-Lying Rectal Cancer显示文摘 | Norio Saito Masaaki Ito Akihiro Kobayashi Yusuke Nishizawa Motohiro Kojima Yuji Nishizawa Masanori Sugito | 2014 | Annals of Surgical Oncology2014，，11： | 1 |
| 15 | Cytosolic Double-Stranded DNA as a Damage-Associated Molecular Pattern Induces the Inflammatory Response in Rat Pancreatic Stellate Cells: A Plausible Mechanism for Tissue Injury-Associated Pancreatitis显示文摘 | Taichi Nakamura Tetsuhide Ito Hisato Igarashi Masahiko Uchida Masayuki Hijioka Takamasa Oono Nao Fujimori Yusuke Niina Koichi Suzuki Robert T. Jensen Ryoichi Takayanagi Zoltan Rakonczay | 2012 | International Journal of Inflammation2012，，： | 1 |
| 16 | Insulin/Foxo Pathway Regulates Expression Levels of Adiponectin Receptors and Adiponectin Sensitivity显示文摘 | Atsushi Tsuchida Toshimasa Yamauchi Yusuke Ito | 2004 | Journal of Biological Chemistry2004，279，30： | 1 |
| 17 | Diagnostic imaging in the preoperative management of lung cancer显示文摘 | Kazuhiro Imai Yoshihiro Minamiya Hajime Saito Satoru Motoyama Yusuke Sato Aki Ito Kei Yoshino Satoshi Kudo Shinogu Takashima Yasushi Kawaharada Nobuyasu Kurihara Kimito Orino Jun-ichi Ogawa | 2014 | Surgery Today2014，，7： | 1 |
| 18 | The abiotic stress-responsive NAC-type transcription factor OsNAC5 regulates stress-inducible genes and stress tolerance in rice显示文摘 | Hironori Takasaki Kyonoshin Maruyama Satoshi Kidokoro Yusuke Ito Yasunari Fujita Kazuo Shinozaki Kazuko Yamaguchi-Shinozaki Kazuo Nakashima | 2010 | Molecular Genetics and Genomics2010，，3： | 1 |
| 19 | Airborne electromagnetic and magnetic surveys for long tunnel construction design显示文摘 | Kenji Okazaki Toru Mogi Mitsuru Utsugi Yoshihiko Ito Hideki Kunishima Takashi Yamazaki Yukitsugu Takahashi Takeshi Hashimoto Yusuke Ymamaya Hisatoshi Ito Hideshi Kaieda Kazuhiro Tsukuda Youichi Yuuki Akira Jomori | 2011 | Physics and Chemistry of the Earth2011，，16： | 1 |
| 20 | Comprehensive analysis of rice DREB2-type genes that encode transcription factors involved in the expression of abiotic stress-responsive genes显示文摘 | Satoko Matsukura Junya Mizoi Takumi Yoshida Daisuke Todaka Yusuke Ito Kyonoshin Maruyama Kazuo Shinozaki Kazuko Yamaguchi-Shinozaki | 2010 | Molecular Genetics and Genomics2010，，2： | 1 |
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